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The Veterinary clinics of North America. Equine practice1987; 3(2); 429-436; doi: 10.1016/s0749-0739(17)30685-5

Medical management of spinal cord disease.

Abstract: In spinal cord disease of horses, a complete history, neurologic examination, and adjunctive diagnostic procedures are very helpful in establishing a tentative diagnosis; however, a definitive diagnosis may be difficult or impossible to establish antemortem. Medical management should be initiated with full consideration of possible etiologies and knowledge of the effects and consequences of medical therapies. This article discusses the drugs commonly used in the management of spinal cord disease and the rationale for their use.
Publication Date: 1987-08-01 PubMed ID: 3113696DOI: 10.1016/s0749-0739(17)30685-5Google Scholar: Lookup
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Summary

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The research article focuses on the medical management of spinal cord diseases in horses, highlighting the crucial role of a full history, neurologic evaluation and further diagnostics in making an initial diagnosis, and the challenges in reaching a definitive diagnosis. The paper also explores various drugs currently used in the management of such diseases, explaining their effects and implications.

Importance of Comprehensive History and Neurologic Examination

  • The study points out that for horses with spinal cord disease, taking a complete history and conducting a rigorous neurologic examination are vital first steps for making a preliminary diagnosis. A detailed history can provide initial insight into the nature of the disease, including its onset, duration, progression, and any associated symptoms.
    The neurologic examination can highlight abnormalities in the horse’s nervous system, pointing the clinician towards potential underlying problems in the spinal cord.

Role of Adjunctive Diagnostic Procedures

  • Additional diagnostic procedures are also crucial in making an initial diagnosis. These could include imaging modalities such as radiography or magnetic resonance imaging (MRI), which can reveal structural abnormalities in the spinal cord. Other tests could involve cerebrospinal fluid analysis or nerve conduction studies to evaluate the functional state of the spinal cord.

Challenges in Reaching a Definitive Diagnosis

  • Finding a definitive diagnosis for spinal cord diseases in horses can be challenging and in some cases, may not be feasible while the animal is still alive. The complexity of the spinal cord, the wide range of potential diseases and their overlapping symptoms, and limitations in available diagnostic tools can all contribute to these challenges.

Medical Therapies for Spinal Cord Disease

  • The article also delves into the medical therapies used to manage these conditions in horses, emphasizing that treatment must be based on a comprehensive understanding of possible causes and the effects and consequences of each therapy. Drugs commonly used in treating spinal cord diseases are discussed, providing insight into their role in managing the symptoms and progression of these diseases.

Rationale for Drug Use

  • Finally, the researchers explore the rationale behind the use of these drugs. This helps to illustrate the thought process and evidence-based decision making that goes into selecting appropriate therapies for spinal cord diseases, increasing the chances of successful treatment and management.

Cite This Article

APA
Stewart RH, Griffiths JP. (1987). Medical management of spinal cord disease. Vet Clin North Am Equine Pract, 3(2), 429-436. https://doi.org/10.1016/s0749-0739(17)30685-5

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 3
Issue: 2
Pages: 429-436

Researcher Affiliations

Stewart, R H
    Griffiths, J P

      MeSH Terms

      • Adrenal Cortex Hormones / therapeutic use
      • Animals
      • Dimethyl Sulfoxide / therapeutic use
      • Folic Acid Antagonists / therapeutic use
      • Horse Diseases / drug therapy
      • Horses
      • Mannitol / therapeutic use
      • Spinal Cord Diseases / drug therapy
      • Spinal Cord Diseases / veterinary
      • Vitamin E / therapeutic use

      Citations

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