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The Veterinary clinics of North America. Equine practice2009; 25(2); 283-301; doi: 10.1016/j.cveq.2009.04.013

New perspectives in equine gastric ulcer syndrome.

Abstract: Equine gastric ulcer syndrome (EGUS) is common in horses. A history of mild intermitted recurrent colic signs after eating is noted in many horses. Management of horses with abdominal pain caused by gastric ulcers is especially difficult, because non-steroidal anti-inflammatory agents, typically used to control abdominal pain, may exacerbate this condition. Effective pharmacologic agents are available to treat EGUS and eliminate abdominal pain, but more comprehensive measures of environmental and dietary management are needed to manage horses with EGUS and prevent recurrence. This article focuses on the history, clinical signs, diagnosis, and management of horses with abdominal pain associated with gastric ulcers. The primary goal is to provide an understanding of EGUS and to review effective pain management and specific antiulcer treatments and management strategies in horses with EGUS.
Publication Date: 2009-07-08 PubMed ID: 19580940DOI: 10.1016/j.cveq.2009.04.013Google Scholar: Lookup
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  • Journal Article

Summary

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This research article focuses on the impact, diagnosis, and management strategies for Equine gastric ulcer syndrome (EGUS) frequently observed in horses. The study highlights the effectiveness of pharmacological agents to treat EGUS and suggests the need for broader management methods such as environmental and dietary adjustments for preventing recurrence of the syndrome.

Understanding EGUS

  • Equine gastric ulcer syndrome (EGUS) is a disease that’s prevalent amongst horses, often causing intermittent, recurrent colic signs post-feeding.
  • This condition can become challenging to manage as the non-steroidal anti-inflammatory agents (NSAIDs) commonly used to control the abdominal pain can actually worsen the condition.

Analysing Treatment Options

  • Whilst specific pharmacological agents have proven effective in treating EGUS and eliminating the resultant abdominal pain, the article stresses the importance of broader, more encompassing measures for managing this condition.
  • Such comprehensive strategies would include modifications in environmental and dietary management for the horses suffering from EGUS.

Highlighting the Importance of Multifaceted Care

  • It is not sufficient to merely treat the symptoms of EGUS, but to prevent its recurrence, it’s important to understand and address the underlying causes.
  • This understanding is essential in treating and managing horses with this syndrome and is needed to develop informed, efficacious strategies that address the disease’s root causes.

Diagnosis and Management

  • This research delves into the history, noticeable clinical signs, the diagnostic process, and management of horses dealing with the abdominal pain triggered by gastric ulcers.
  • The overall objective of this research is to advance the understanding of EGUS and explore pain relief methods, specific antiulcer treatments, and overall strategies to manage horses suffering from this syndrome.

Cite This Article

APA
Videla R, Andrews FM. (2009). New perspectives in equine gastric ulcer syndrome. Vet Clin North Am Equine Pract, 25(2), 283-301. https://doi.org/10.1016/j.cveq.2009.04.013

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 25
Issue: 2
Pages: 283-301

Researcher Affiliations

Videla, Ricardo
  • Department of Large Animal Clinical Sciences, The University of Tennessee College of Veterinary Medicine, 2407 River Drive, Knoxville, TN 37996, USA. fandrews@lsu.edu
Andrews, Frank M

    MeSH Terms

    • Animal Husbandry
    • Animals
    • Anti-Inflammatory Agents, Non-Steroidal / adverse effects
    • Bacterial Infections / complications
    • Bacterial Infections / veterinary
    • Diet / adverse effects
    • Horse Diseases / diagnosis
    • Horse Diseases / etiology
    • Horse Diseases / prevention & control
    • Horse Diseases / therapy
    • Horses
    • Stomach Ulcer / etiology
    • Stomach Ulcer / prevention & control
    • Stomach Ulcer / therapy
    • Stomach Ulcer / veterinary

    Citations

    This article has been cited 11 times.
    1. Frippiat T, Bonhomme M, Dyson S, Votion DM. Evaluation of Owner-Reported Clinical Signs and Fecal Occult Blood Tests as Predictors of Equine Gastric Ulcer Syndrome in Competition Dressage Horses. J Vet Intern Med 2025 Nov-Dec;39(6):e70248.
      doi: 10.1111/jvim.70248pubmed: 41055229google scholar: lookup
    2. Zhou K, Dong Z, Zhou X, Zhai B, Li B, Zhang J, Cheng F. The Prevalence of Gastric Ulcer Syndrome in 395 Horses in Jiangyin City, China, Jiangsu Province. Animals (Basel) 2024 Dec 17;14(24).
      doi: 10.3390/ani14243636pubmed: 39765539google scholar: lookup
    3. Vokes J, Lovett A, Sykes B. Equine Gastric Ulcer Syndrome: An Update on Current Knowledge. Animals (Basel) 2023 Apr 5;13(7).
      doi: 10.3390/ani13071261pubmed: 37048517google scholar: lookup
    4. Lo Feudo CM, Stucchi L, Conturba B, Stancari G, Zucca E, Ferrucci F. Equine Gastric Ulcer Syndrome affects fitness parameters in poorly performing Standardbred racehorses. Front Vet Sci 2022;9:1014619.
      doi: 10.3389/fvets.2022.1014619pubmed: 36504861google scholar: lookup
    5. Silva CJFL, Trindade KLG, Cruz RKS, Manso HECCC, Coelho CS, Filho JDR, Nogueira CEW, Aragona F, Fazio F, Manso Filho HC. Effects of the Ingestion of Ripe Mangoes on the Squamous Gastric Region in the Horse. Animals (Basel) 2022 Nov 9;12(22).
      doi: 10.3390/ani12223084pubmed: 36428312google scholar: lookup
    6. Hwang H, Dong HJ, Han J, Cho S, Kim Y, Lee I. Prevalence and treatment of gastric ulcers in Thoroughbred racehorses of Korea. J Vet Sci 2022 Mar;23(2):e19.
      doi: 10.4142/jvs.21247pubmed: 35187877google scholar: lookup
    7. Poltep K, Tesena P, Yingchutrakul Y, Taylor J, Wongtawan T. Optimisation of a serum albumin removal protocol for use in a proteomic study to identify the protein biomarkers for silent gastric ulceration in horses. J Equine Sci 2018 Sep;29(3):53-60.
      doi: 10.1294/jes.29.53pubmed: 30250392google scholar: lookup
    8. Lohmann KL, Allen AL. Chronic active interstitial pancreatitis as a cause of transverse colonic obstruction and colic in a horse. Can Vet J 2015 Nov;56(11):1177-80.
      pubmed: 26538675
    9. Sykes BW, Hewetson M, Hepburn RJ, Luthersson N, Tamzali Y. European College of Equine Internal Medicine Consensus Statement--Equine Gastric Ulcer Syndrome in Adult Horses. J Vet Intern Med 2015 Sep-Oct;29(5):1288-99.
      doi: 10.1111/jvim.13578pubmed: 26340142google scholar: lookup
    10. Birkmann K, Junge HK, Maischberger E, Wehrli Eser M, Schwarzwald CC. Efficacy of omeprazole powder paste or enteric-coated formulation in healing of gastric ulcers in horses. J Vet Intern Med 2014 May-Jun;28(3):925-33.
      doi: 10.1111/jvim.12341pubmed: 24628650google scholar: lookup
    11. Dakin SG, Dudhia J, Smith RK. Resolving an inflammatory concept: the importance of inflammation and resolution in tendinopathy. Vet Immunol Immunopathol 2014 Apr 15;158(3-4):121-7.
      doi: 10.1016/j.vetimm.2014.01.007pubmed: 24556326google scholar: lookup