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EFSA journal. European Food Safety Authority2023; 21(4); e07974; doi: 10.2903/j.efsa.2023.7974

Safety and efficacy of a feed additive consisting of Lactiplantibacillus plantarum DSM 11520 for horses, dogs, cats and pet rabbits (Animal Probiotics Sweden AB).

Abstract: Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on DSM 11520 when used as a technological additive (acidity regulator) in feed for horses, dogs, cats and pet rabbits. The additive is intended to be incorporated into oat-derived products (ca. 55% moisture content), carrot root-derived products (≥ 90% moisture) and coconut flesh-derived products (≥ 90% moisture) at a minimum inclusion level of 8.0 × 10 CFU/kg of the feed material under scope. The bacterial species is considered by EFSA to be suitable for the qualified presumption of safety (QPS) approach to safety assessment. The identity of the strain has been clearly established and it did not show acquired resistance to antibiotics of human and veterinary importance. The FEEDAP Panel concluded that the use of this strain in animal nutrition is safe for the target species, consumers of horse meat and the environment. Regarding the user safety, the additive DSM 11520 is not irritant to skin or eyes in the product tested containing maltodextrin and oat bran as carriers, but owing to its proteinaceous nature, it should be considered a respiratory sensitiser. No conclusions can be drawn on the skin sensitisation potential of the additive. The FEEDAP Panel concluded that incorporation of DSM 11520 at a minimum concentration of 8.0 × 10 CFU/kg into oat-derived products (ca. 55% moisture content), carrot root-derived products (≥ 90% moisture) and coconut flesh-derived products (≥ 90% moisture) has the potential to reduce the pH of these feedingstuffs.
Publication Date: 2023-04-20 PubMed ID: 37089175PubMed Central: PMC10116392DOI: 10.2903/j.efsa.2023.7974Google Scholar: Lookup
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  • Journal Article

Summary

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The research paper discusses the safety and effectiveness of Lactiplantibacillus plantarum DSM 11520, a bacterial additive, in feed for pets such as horses, dogs, cats, and rabbits. The findings suggest that this additive has potential benefits in maintaining the pH level of various foods and does not pose a risk to the animals, the environment, or humans consuming horse meat.

Research Purpose and Methodology

  • The study was conducted to evaluate the safety and efficacy of DSM 11520, a bacterial strain of Lactiplantibacillus plantarum, as a technological additive in animal feed. The use of additive was focused on oat-derived, carrot root-derived, and coconut flesh-derived foods with specific moisture content.
  • The research was initiated upon request from the European Commission and conducted by the European Food Safety Authority (EFSA).
  • DSM 11520’s safety was assessed using the qualified presumption of safety (QPS) approach. This method is based on reasonable evidence showing a lack of pathogenic properties and the feasibility of establishing the strain’s identity.

Key Findings

  • DSM 11520 was found to be safe for the animals consuming the feed, the consumers of horse meat, and did not pose any environmental hazard.
  • No acquired resistance to antibiotics of human and veterinary importance was observed in the bacterial strain, confirming its safety.
  • While not irritating to the skin or eyes, due to its proteinaceous nature, it might potentially cause respiratory sensitization. No conclusions were made regarding its potential for skin sensitization.
  • The research concluded that the addition of DSM 11520 at a concentration of 8.0 x 10 CFU/kg can effectively reduce the pH of the foodstuff. This indicates its functionality as a acidity regulator, which can help maintain the freshness and quality of the feed.

Research Limitations and Future Scope

  • Despite positive findings, the research did not provide data on the potential of DSM 11520 additives to cause skin sensitization. Further research might be needed to investigate this aspect.
  • Although the research concludes that DSM 11520 is safe for human consumption through horse meat, it specifies no comment about other animal derivatives like those from dogs, cats, and rabbits. Further studies may be needed to confirm the safety in these contexts.

Cite This Article

APA
Bampidis V, Azimonti G, Bastos ML, Christensen H, Dusemund B, Durjava M, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Sanz Y, Villa RE, Woutersen R, Anguita M, Brozzi R, Galobart J, Innocenti M, García-Cazorla Y. (2023). Safety and efficacy of a feed additive consisting of Lactiplantibacillus plantarum DSM 11520 for horses, dogs, cats and pet rabbits (Animal Probiotics Sweden AB). EFSA J, 21(4), e07974. https://doi.org/10.2903/j.efsa.2023.7974

Publication

ISSN: 1831-4732
NlmUniqueID: 101642076
Country: United States
Language: English
Volume: 21
Issue: 4
Pages: e07974
PII: e07974

Researcher Affiliations

Bampidis, Vasileios
    Azimonti, Giovanna
      Bastos, Maria de Lourdes
        Christensen, Henrik
          Dusemund, Birgit
            Durjava, Mojca
              Kouba, Maryline
                López-Alonso, Marta
                  López Puente, Secundino
                    Marcon, Francesca
                      Mayo, Baltasar
                        Pechová, Alena
                          Petkova, Mariana
                            Ramos, Fernando
                              Sanz, Yolanda
                                Villa, Roberto Edoardo
                                  Woutersen, Ruud
                                    Anguita, Montserrat
                                      Brozzi, Rosella
                                        Galobart, Jaume
                                          Innocenti, Matteo
                                            García-Cazorla, Yolanda

                                              References

                                              This article includes 11 references
                                              1. EFSA. Opinion of the Scientific Committee on a request from EFSA on the introduction of a Qualified Presumption of Safety (QPS) approach for assessment of selected microorganisms referred to EFSA. EFSA Journal 2007;5(12):587, 16 pp.
                                                doi: 10.2903/j.efsa.2007.587google scholar: lookup
                                              2. . EFSA statement on the requirements for whole genome sequence analysis of microorganisms intentionally used in the food chain.. EFSA J 2021 Jul;19(7):e06506.
                                                doi: 10.2903/j.efsa.2021.6506pmc: PMC8317053pubmed: 34335919google scholar: lookup
                                              3. EFSA BIOHAZ Panel, Koutsoumanis K, Allende A, Álvarez‐Ordóñez A, Bolton D, Bover‐Cid S, Chemaly M, De Cesare A, Hilbert F, Lindqvist R, Nauta M, Peixe L, Ru G, Simmons M, Skandamis P, Suffredini E, Cocconcelli PS, Fernández Escámez PS, Prieto Maradona M, Querol A, Sijtsma L, Suarez JE, Sundh I, Vlak JM, Barizzone F, Hempen M, Correia S, Herman L. Scientific Opinion on the ‘Update of the list of Qualified Presumption of Safety (QPS) recommended microorganisms intentionally added to food or feed as notified to EFSA’. EFSA Journal 2023;21(1):7747, 27 pp.
                                                doi: 10.2903/j.efsa.2023.7747google scholar: lookup
                                              4. EFSA FEEDAP Panel. Guidance on studies concerning the safety of use of the additive for users/workers. EFSA Journal 2012;10(1):2539, 5 pp.
                                                doi: 10.2903/j.efsa.2012.2539google scholar: lookup
                                              5. EFSA FEEDAP Panel, Rychen G, Aquilina G, Azimonti G, Bampidis V, Bastos ML, Bories G, Chesson A, Cocconcelli PS, Flachowsky G, Gropp J, Kolar B, Kouba M, López‐Alonso M, López Puente S, Mantovani A, Mayo B, Ramos F, Saarela M, Villa RE, Wallace RJ, Wester P, Anguita M, Dujardin B, Galobart J, Innocenti ML. Guidance on the assessment of the safety of feed additives for the consumer. EFSA Journal 2017;15(10):5022, 17 pp.
                                                doi: 10.2903/j.efsa.2017.5022google scholar: lookup
                                              6. Rychen G, Aquilina G, Azimonti G, Bampidis V, Bastos ML, Bories G, Chesson A, Cocconcelli PS, Flachowsky G, Gropp J, Kolar B, Kouba M, López-Alonso M, López Puente S, Mantovani A, Mayo B, Ramos F, Saarela M, Villa RE, Wallace RJ, Wester P, Anguita M, Galobart J, Innocenti ML. Guidance on the identity, characterisation and conditions of use of feed additives.. EFSA J 2017 Oct;15(10):e05023.
                                                doi: 10.2903/j.efsa.2017.5023pmc: PMC7010039pubmed: 32625313google scholar: lookup
                                              7. Rychen G, Aquilina G, Azimonti G, Bampidis V, Bastos ML, Bories G, Chesson A, Cocconcelli PS, Flachowsky G, Gropp J, Kolar B, Kouba M, López-Alonso M, López Puente S, Mantovani A, Mayo B, Ramos F, Saarela M, Villa RE, Wallace RJ, Wester P, Anguita M, Galobart J, Innocenti ML, Martino L. Guidance on the assessment of the safety of feed additives for the target species.. EFSA J 2017 Oct;15(10):e05021.
                                                doi: 10.2903/j.efsa.2017.5021pmc: PMC7009839pubmed: 32625311google scholar: lookup
                                              8. Rychen G, Aquilina G, Azimonti G, Bampidis V, Bastos ML, Bories G, Chesson A, Cocconcelli PS, Flachowsky G, Gropp J, Kolar B, Kouba M, López-Alonso M, López Puente S, Mantovani A, Mayo B, Ramos F, Saarela M, Villa RE, Wallace RJ, Wester P, Anguita M, Galobart J, Innocenti ML, Martino L. Guidance on the assessment of the efficacy of feed additives.. EFSA J 2018 May;16(5):e05274.
                                                doi: 10.2903/j.efsa.2018.5274pmc: PMC7009555pubmed: 32625911google scholar: lookup
                                              9. Rychen G, Aquilina G, Azimonti G, Bampidis V, Bastos ML, Bories G, Chesson A, Cocconcelli PS, Flachowsky G, Gropp J, Kolar B, Kouba M, López-Alonso M, López Puente S, Mantovani A, Mayo B, Ramos F, Saarela M, Villa RE, Wallace RJ, Wester P, Glandorf B, Herman L, Kärenlampi S, Aguilera J, Anguita M, Brozzi R, Galobart J. Guidance on the characterisation of microorganisms used as feed additives or as production organisms.. EFSA J 2018 Mar;16(3):e05206.
                                                doi: 10.2903/j.efsa.2018.5206pmc: PMC7009341pubmed: 32625840google scholar: lookup
                                              10. EFSA FEEDAP Panel, Bampidis V, Bastos M, Christensen H, Dusemund B, Kouba M, Kos Durjava M, López‐Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Sanz Y, Villa RE, Woutersen R, Brock T, de Knecht J, Kolar B, van Beelen P, Padovani L, Tarres‐Call J, Vettori MV, Azimonti G. Guidance on the assessment of the safety of feed additives for the environment. EFSA Journal 2019;17(4):5648, 78 pp.
                                                doi: 10.2903/j.efsa.2019.5648google scholar: lookup
                                              11. EFSA FEEDAP Panel, Bampidis V, Azimonti G, Bastos ML, Christensen H, Dusemund B, Kos Durjava M, Kouba M, López‐Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Sanz Y, Villa RE, Woutersen R, Herman L, Glandorf B, Prieto MM, Saarela M, Brozzi R. ScientificOpinion on the safety and efficacy of ProEquo® (Lactobacillus plantarum DSM 11520) as a feedadditive for horses. EFSA Journal 2020;18(5):6143, 9 pp.
                                                doi: 10.2903/j.efsa.2020.6143google scholar: lookup

                                              Citations

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