Use of Biologics and Stem Cells for Wound Healing in the Horse.

Abstract: Treatment of skin wounds is a high priority in veterinary medicine because healthy uncompromised skin is essential for the well-being of horses. Stem cells and other biologic therapies offer benefits by reducing the need for surgical procedures and conventional antibiotics. Evidence from in vitro studies and small in vivo trials supports the use of equine stem cells and biologics for the treatment of acute and chronic cutaneous wounds. Larger clinical trials are warranted to better evaluate the regenerative and immunological responses to these treatments. Additionally, delivery methods and treatment schedules should be optimized to improve efficacy of these novel therapies.
Publication Date: 2023-07-11 PubMed ID: 37442731DOI: 10.1016/j.cveq.2023.06.003Google Scholar: Lookup
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Summary

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The research study explores how biologics and stem cells can be effectively used for wound healing in horses. The study emphasizes the treatment’s potential above conventional methods due to lesser need for surgical procedures and antibiotics.

Overview of the Study

  • The research paper focuses on improving treatments for skin wounds in horses, which is considered a significant priority in veterinary medicine.
  • Uncompromised, healthy skin is crucial for a horse’s well-being, making any wounds on its skin a concern for veterinarians.
  • The study posits that the use of stem cells and other biologic therapies could present a revolutionary method of treatment. These therapies could reduce the need for surgical procedures and the excessive use of conventional antibiotics.

In-depth Findings

  • The research provides evidence from preliminary in vitro studies and small-scale in vivo trials.
  • Findings from these studies suggest the potential benefits of equine stem cells and biologics for treating both acute and chronic cutaneous wounds in horses.
  • Although the results are promising, the study calls for larger clinical trials to better evaluate the regenerative and immunological responses prompted by these novel treatments.

Recommendations and Future Directions

  • The researchers recommend further investigations to determine the optimal delivery methods and treatment schedules for these therapies to improve their effectiveness.
  • With the current standard treatments having severe drawbacks such as the necessity of surgical procedures and overreliance on traditional antibiotics, the development of these novel therapies could revolutionize veterinary medicine.
  • More rigorous and in-depth study are needed to fully assess the potential benefits and any possible drawbacks of these innovative treatments.

Cite This Article

APA
Harman RM, Rajesh A, Van de Walle GR. (2023). Use of Biologics and Stem Cells for Wound Healing in the Horse. Vet Clin North Am Equine Pract. https://doi.org/10.1016/j.cveq.2023.06.003

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English

Researcher Affiliations

Harman, Rebecca M
  • Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
Rajesh, Aarthi
  • Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
Van de Walle, Gerlinde R
  • Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA. Electronic address: grv23@cornell.edu.

Citations

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