Fenbendazole is a dewormer used to treat certain gastrointestinal parasites in horses. Although it has long been part of equine parasite-control programs, widespread anthelmintic resistance has reduced its effectiveness against some common parasites. The drug disrupts microtubule formation in target...

Acepromazine is one of the most commonly used sedatives in equine veterinary medicine. It is valued for its ability to reduce anxiety and make horses easier and safer to handle during veterinary procedures, farrier care, transportation, and other potentially stressful...

Local anesthetics are among the most commonly used medications in equine veterinary medicine. These drugs temporarily block nerve conduction, preventing pain signals from traveling from a specific area of the body to the brain. By providing targeted pain relief without...

Lidocaine is best known as a local anesthetic used to numb tissues during medical procedures, but this versatile drug has applications beyond local pain control. In equine medicine, lidocaine is administered intravenously as a systemic therapy to manage pain, reduce...

SGLT2 inhibitors are emerging as a novel therapeutic option in equine medicine, particularly for horses and ponies affected by severe insulin resistance and endocrinopathic laminitis. Interest in these medications has increased rapidly in recent years as veterinarians look for additional...

Prednisone and prednisolone are corticosteroid medications used in veterinary medicine to reduce inflammation and suppress abnormal immune responses. Prednisolone is generally preferred in horses because it is the active form of the medication and is absorbed more reliably than prednisone....

Omeprazole is a cornerstone of managing gastric ulcers in horses, working to reduce stomach acid and promote healing. Equine Gastric Ulcer Syndrome (EGUS) is extremely common, particularly in performance horses exposed to intensive training, travel, and dietary challenges. In equine...

Diphenhydramine is an antihistamine commonly used in horses to manage allergic reactions, including hives, insect bite hypersensitivity, and other inflammatory skin conditions. While it is widely recognized under brand names like Benadryl®, its use in equine care is typically off-label...

Ketamine is a widely used medication in equine veterinary medicine, best known for its role as a fast-acting anesthetic. It is commonly administered during surgical procedures, diagnostic imaging, and emergency interventions, where it helps induce and maintain anesthesia while preserving...

Trimethoprim sulfadiazine, brand name Equisul-SDT®, is a combination antibiotic widely used in equine medicine for the treatment of bacterial infections. This medication combines two antimicrobial drugs that work together to stop bacteria from growing and multiplying, making it effective against...

Cisapride is a prokinetic medication used in horses to stimulate movement in the gastrointestinal tract, helping restore normal gut motility when digestion slows or stops. It is most commonly used in cases of postoperative ileus, severe gastrointestinal hypomotility, or other...

Methocarbamol is a centrally acting muscle relaxant commonly used in horses to treat skeletal muscle spasms. These spasms can occur during conditions that cause muscle inflammation or injury and are often associated with disorders such as exertional rhabdomyolysis, commonly known...

Dantrolene is a skeletal muscle relaxant used in horses to manage conditions involving excessive skeletal muscle contraction or muscle damage, most notably exertional rhabdomyolysis (tying-up). Exertional rhabdomyolysis occurs when muscle cells become damaged during or after exercise, leading to pain,...

Quinidine is an antiarrhythmic medication used in horses for the treatment of atrial fibrillation (AF), the most common type of cardiac arrhythmia that warrants medical intervention. Atrial fibrillation occurs when the upper chambers of the heart (the atria) beat in...