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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
The uterus as a source of oxytocin in cyclic mares.
Journal of reproduction and fertility. Supplement    January 1, 2000   Issue 56 281-287 
Stout TA, Lamming GE, Allen WR.In a recent study, continuous administration of oxytocin by subcutaneous minipump to mares from day 8 to 20 after ovulation prevented luteolysis in most of the treated but none of the control mares, indicating a role for oxytocin in cyclical luteolysis in mares. In the present study, measurement of oxytocin concentrations in uterine flushings recovered from nine mares during days 14-18 after ovulation gave values that were many times higher than those measured concurrently in peripheral plasma. Furthermore, intrauterine administration of oxytocin to four mares on day 14 after ovulation stimula...
T cell-rich B cell lymphosarcoma in the tongue of a horse.
The Veterinary record    December 28, 1999   Volume 145, Issue 19 554-555 doi: 10.1136/vr.145.19.554
Rhind SM, Dixon PM.No abstract available
Prevalence of antibodies to Neospora sp. in horses from Alabama and characterisation of an isolate recovered from a naturally infected horse [corrected].
International journal for parasitology    December 23, 1999   Volume 29, Issue 10 1537-1543 doi: 10.1016/s0020-7519(99)00140-x
Cheadle MA, Lindsay DS, Rowe S, Dykstra CC, Williams MA, Spencer JA, Toivio-Kinnucan MA, Lenz SD, Newton JC, Rolsma MD, Blagburn BL.An IFAT was used to determine the prevalence of Neospora-specific IgG antibodies in serum from Alabama horses. Serum samples (n = 536) were from asymptomatic horses routinely submitted for equine infectious anaemia virus infection testing. We also subjected a 13-year-old horse with CNS disease to necropsy examination for isolation and in vitro cultivation of protozoal organisms. In antemortem tests, this horse was positive for antibodies to Neospora sp. in the IFAT and western immunoblot. Results of the prevalence survey indicated that IgG antibodies to Neospora were present in 62 (11.5%) of t...
The use of scintigraphy in the diagnosis of aortic-iliac thrombosis in a horse.
Equine veterinary journal    December 22, 1999   Volume 31, Issue 6 537-541 doi: 10.1111/j.2042-3306.1999.tb03866.x
Boswell JC, Marr CM, Cauvin ER, Schramme MC.No abstract available
Review of equine laparoscopy and an analysis of 158 laparoscopies in the horse.
Equine veterinary journal    December 22, 1999   Volume 31, Issue 6 456-464 
Walmsley JP.No abstract available
[Rhinopneumonia or mycotoxin intoxication? Neurologic phenomena in horses from a riding school].
Tijdschrift voor diergeneeskunde    December 22, 1999   Volume 124, Issue 22 679-681 
Sloet van Oldruitenborgh-Oosterbaan MM, Schipper FC, Goehring LS, Gremmels JF.In the course of several days most of the 40 riding-school horses turned out in paddocks developed ataxia of variable severity. Five of these horses showed severe ataxia and tremors, became paralyzed and were euthanized. Eleven privately-owned horses which were stabled on the same premises showed no clinical signs. The most likely diagnosis seemed to be the 'neurological form of EHV1', although the signs were not entirely typical. A few weeks later a second outbreak occurred among the riding-school horses and one of the privately-owned horses also showed signs of ataxia. In the meantime it had...
Effect of prophylactic administration of hyperimmune plasma to prevent Rhodococcus equi infection on foals from endemically affected farms.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B    December 22, 1999   Volume 46, Issue 9 641-648 doi: 10.1046/j.1439-0450.1999.00284.x
Higuchi T, Arakawa T, Hashikura S, Inui T, Senba H, Takai S.The effect on foals of prophylactic administration of hyperimmune plasma to prevent R. equi infection was investigated on three farms at which R. equi infection was endemic. Sixteen foals between 10 and 39 days of age were intravenously given 1-21 of hyperimmune plasma. ELISA antibody titres against R. equi were significantly increased and maintained at high levels for over 30 days in most of the recipient foals. The prevalence of R. equi infection was 6.3% (1/16) in the foals that received the immune plasma, and 26.3% (5/19) in the control foals not given the immune plasma on the three farms....
Monensin poisoning in Brazilian horses.
Veterinary and human toxicology    December 11, 1999   Volume 41, Issue 6 383-385 
Bezerra PS, Driemeier D, Loretti AP, Riet-Correa F, Kamphues J, de Barros CS.Three outbreaks of monensin poisoning caused 12 deaths in 16 horses. The illnesses were associated with the ingestion of the same batch of a commercial ration labeled for feeder calves which contained 180 +/- 20 ppm sodium monensin. The morbidity rate was 100% and lethality was 60%, 75%, and 100%. Clinical signs were tachycardia and cardiac arrythmia, groaning, incoordination, sudoresis, recumbency, and paddling movements with the limbs before death. Two horses had dark discolored urine (myoglobinuria). Serum levels of creatine phosphokinase activity were increased. Main necropsy findings were...
Sulfidoleukotriene generation from peripheral blood leukocytes of horses affected with insect bite dermal hypersensitivity.
Veterinary immunology and immunopathology    December 10, 1999   Volume 71, Issue 3-4 307-320 doi: 10.1016/s0165-2427(99)00107-5
Marti E, Urwyler A, Neuenschwander M, Eicher R, Meier D, de Weck AL, Gerber H, Lazary S, Dahinden CA.Sulfidoleukotrienes (sLT) generated in vitro after incubation of equine peripheral blood leukocytes (PBL) with different inducing agents were determined in 18 healthy and 16 insect bite dermal hypersensitivity (IDH)-affected horses. PBL from these 32 horses were stimulated with Concanavalin A, Parascaris equorum, Culicoides nubeculosus and Simulium extracts, and with a six-Grass mix. The cells of all but four horses generated sLT after incubation with Concanavalin A; these four horses did also not produce sLT with the other inducing agents. Of the 28 remaining horses (12 affected with IDH and ...
Thoracoabdominal aortic aneurysm in two ponies.
The Veterinary record    December 4, 1999   Volume 145, Issue 23 675-676 
Simoens P, Vercruysse J, De Jonghe S, Ducatelle R.No abstract available
Inhaled carbon monoxide concentration during halothane or isoflurane anesthesia in horses.
Veterinary surgery : VS    December 3, 1999   Volume 28, Issue 6 506-512 doi: 10.1111/j.1532-950x.1999.00506.x
Dodam JR, Branson KR, Gross ME, Petroski GF.The purpose of this study was to assess carbon monoxide (CO) exposure during equine anesthesia with either halothane (H) or isoflurane (I) delivered in a circle rebreathing system. Methods: Prospective clinical investigation. Methods: Fifty client-owned horses. Methods: Horses were randomly assigned for anesthetic maintenance with H (n = 26) or I (n = 24). Two large animal anesthetic machines were used and assigned to a single agent for 2-4 weeks at a time. Machines were disassembled and soda lime changed prior to switching anesthetic agents. Inhalant anesthetic concentration and CO concentrat...
Intestinal adenocarcinoma causing recurrent colic in the horse.
The Canadian veterinary journal = La revue veterinaire canadienne    November 26, 1999   Volume 40, Issue 10 729-730 
Harvey-Micay J.An 8-year-old, Thoroughbred-cross mare presented with recurrent colic. Exploratory laparotomy revealed a large mass near the right dorsal colon; white, raised foci on the liver; and enlarged mesenteric lymph nodes. Cytological examination of biopsies revealed neoplastic cells. The diagnosis of adenocarcinoma was confirmed by histological examination.
Outbreak of acute colitis on a horse farm associated with tetracycline-contaminated sweet feed.
The Canadian veterinary journal = La revue veterinaire canadienne    November 26, 1999   Volume 40, Issue 10 718-720 
Keir AA, Stämpfli HR, Crawford J.Exposure of a group of horses to tetracycline-contaminated feed resulted in acute colitis and subsequent death in one horse and milder diarrhea in 3 others. The most severely affected animal demonstrated clinical and pathological findings typical of colitis X. The other herdmates responded well to administration of zinc bacitracin.
Testicular endocrine function, seasonality and semen quality of the stallion.
Animal reproduction science    November 24, 1999   Volume 57, Issue 1-2 89-98 doi: 10.1016/s0378-4320(99)00050-0
Hoffmann B, Landeck A.To gain further information on gonadal function of the stallion, concentrations of testicular steroids in blood plasma (bpl) and seminal plasma (spl) and their distribution in the ejaculate were determined. Blood and semen samples from a total of 11 stallions were collected from November to July. Estrone (E1), estrone sulfate (E1S), estradiol-17beta (E2beta) and testosterone (T) were determined in bpl and spl, and in addition androstenedione (A), dehydroepiandrosterone (DHEA) and 5alpha-dihydrotestosterone (5alpha-DHT) were measured in spl. At certain points of time, aliquots of an ejaculate w...
Clinical, biochemical, and hygiene assessment of stabled horses provided continuous or intermittent access to drinking water.
American journal of veterinary research    November 24, 1999   Volume 60, Issue 11 1445-1450 
Freeman DA, Cymbaluk NF, Schott HC, Hinchcliff K, McDonnell SM, Kyle B.To compare health, hydration status, and management of stabled pregnant mares provided drinking water continuously or via 1 of 3 intermittent delivery systems. Methods: 22 Quarter Horse (QH) or QH-crossbred mares and 18 Belgian or Belgian-crossbred mares (study 1); 24 QH or QH-crossbred mares and 18 Belgian or Belgian-crossbred mares (study 2). Methods: Stabled horses were provided water continuously or via 1 of 3 intermittent water delivery systems in 2 study periods during a 2-year period. Body temperature, attitude, appetite, water intake, and urine output were recorded daily. Hygiene of ea...
Monthly, daily, and circadian variations of measurements of pulmonary mechanics in horses with chronic obstructive pulmonary disease.
American journal of veterinary research    November 24, 1999   Volume 60, Issue 11 1341-1346 
Jean D, Vrins A, Lavoie JP.To determine temporal variations of pulmonary function in horses without respiratory tract disease (controls) and horses with chronic obstructive pulmonary disease (COPD) and determine whether reversibility of airway obstruction after environmental control can be predicted by response to atropine administration. Methods: 7 COPD-affected and 5 control horses. Methods: Pulmonary function testing was performed monthly during 3 consecutive months, daily for 5 consecutive days, and at 6-hour intervals for 24 hours before and after administration of atropine (0.02 mg/kg of body weight, i.v.) and aft...
Hemodynamic effects of ionized calcium in horses anesthetized with halothane or isoflurane.
American journal of veterinary research    November 24, 1999   Volume 60, Issue 11 1430-1435 
Grubb TL, Benson GJ, Foreman JH, Constable PD, Thurmon JC, Olson WO, Tranquilli WJ, Davis LE.To evaluate the effects of halothane and isoflurane on cardiovascular function and serum total and ionized calcium concentrations in horses, and to determine whether administration of calcium gluconate would attenuate these effects. Methods: 6 clinically normal adult Thoroughbreds. Methods: Catheters were inserted for measurement of arterial blood pressures, pulmonary arterial blood pressures, right ventricular pressure (for determination of myocardial contractility), right atrial pressure, and cardiac output and for collection of arterial blood samples. Anesthesia was then induced with xylazi...
Cardiopulmonary and sedative effects of intravenous administration of low doses of medetomidine and xylazine to adult horses.
American journal of veterinary research    November 24, 1999   Volume 60, Issue 11 1371-1376 
Bueno AC, Cornick-Seahorn J, Seahorn TL, Hosgood G, Moore RM.To determine the cardiopulmonary and sedative effects of medetomidine hydrochloride in adult horses and to compare those effects with effects of an equipotent dose of xylazine hydrochloride. Methods: 10 healthy adult female horses. Methods: 5 horses were given medetomidine (4 microg/kg of body weight, i.v.), and the other 5 were given xylazine (0.4 mg/kg, i.v.). Heart rate, respiratory rate, arterial blood pressures, pulmonary arterial blood pressures, and cardiac output were recorded, and sedation and ataxia scores were assigned before and every 5 minutes after drug administration for 60 minu...
Exercise-induced haemorrhagic lesions in the dorsocaudal extremities of the caudal lobes of the lungs of young thoroughbred horses.
Journal of comparative pathology    November 5, 1999   Volume 121, Issue 4 339-347 doi: 10.1053/jcpa.1999.0331
Oikawa M.The dorsocaudal extremities of the caudal lobes of the lungs of racehorses are vulnerable to exercise-induced pulmonary haemorrhage (EIPH). The morphology of the lungs at these sites was studied in 13 Thoroughbred horses aged 18 to 22 months. These animals, which had been performing low-intensity exercise on a track at maximum running speeds of approximately 5-8.5 metres/second (m/s), were withdrawn from the racehorse training programme for reasons of unsuitability. Lung lesions observed in the dorsocaudal lung extremities in 10 of the 13 horses were not found in the craniodorsal or craniovent...
CT examination of the guttural pouch (auditory tube diverticulum) in Przewalski’s Horse (Equus przewalskii).
The Journal of veterinary medical science    October 27, 1999   Volume 61, Issue 9 1019-1022 doi: 10.1292/jvms.61.1019
Sasaki M, Hayashi Y, Koie H, Yamaya Y, Kimura J, Manglai D, Kawashima S, Endo H, Yamamoto M.The domestic horse (Equus caballus) have the large symmetrical guttural pouches (the auditory tube diverticulum) formed by saccate bulge of the auditory tube. In this study, CT examination was carried out in the head of Przewalski's horse (Equus przewalskii), the only true wild horse living at present. As results of the examination, Przewalski's horse possessed the large symmetrical guttural pouches divided into medial and lateral compartments by the stylohyoid bone. Moreover, the right and left guttural pouches meet each other at the median part to form a thin septum. As CT sections get close...
What is your diagnosis? Femoral and tibial subchondral bone cysts in a horse.
Journal of the American Veterinary Medical Association    October 26, 1999   Volume 215, Issue 8 1097-1098 
Bueno AC, Kaneps AJ, Watrous BJ.No abstract available
Isolates of fungi from symptomatic carthorses in Awassa, Ethiopia.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B    October 21, 1999   Volume 46, Issue 7 443-451 doi: 10.1046/j.1439-0450.1999.00251.x
Etana D.Samples were collected from clinically infected carthorses in Awassa. Fungus species affecting the carthorses were identified. Eight genera of fungal groups were isolated from swabs and skin scrapes taken from symptomatic horses. These included Aspergillus spp., Histoplasma spp., Penicillium spp., Microsporum spp., Trichophyton spp., yeast cells of Candida spp., Cryptococcus spp. and Geotrichum spp. The most frequent isolates were from the genera Aspergillus (48%), Penicillium (39.2%) and Trichophyton (31.6%). Clinical findings are reported, the economic, zoonotic and pathogenetic importance o...
Evaluation of different projections for radiographic detection of tarsal degenerative joint disease in Icelandic horses. Eksell P, Uhlhorn H, Carlsten J.Radiographs from 196 tarsi in 98 Icelandic horses were evaluated to compare the accuracy of four different projections in detecting radiographic signs of degenerative joint disease in the distal tarsus. The extent and localization of tarsal degenerative joint disease found in one projection when reading all four projections of the same tarsus together was compared with the combined findings from all four projections. The results of reading individual radiographic projections without knowledge of the other three projections was also evaluated. Degenerative joint disease was detected most freque...
Computed tomographic evaluation of Finnhorse cadaver forefeet with radiographically problematic findings on the flexor aspect of the navicular bone. Ruohoniemi M, Tervahartiala P.Computed tomography (CT) was performed on 12 Finnhorse cadaver forefeet with known radiographic changes in the navicular bone (poor corticomedullary junction, irregular appearance of the flexor central eminence, uneven or unequal thickness of the flexor cortex, and/or irregular outline of the proximal or distal flexor margin). The purpose was to confirm the radiographic findings and to investigate if further information of the flexor aspect of the bone could be gained with CT. In CT, the midsagittal outline as well as the internal structure of the bones varied greatly. Different combinations o...
What is your diagnosis? Bilateral separation of the proximal femoral epiphysis from the metaphysis (type-I Salter-Harris fracture).
Journal of the American Veterinary Medical Association    October 8, 1999   Volume 215, Issue 7 933-934 
Blaik MA, Hudson JA.No abstract available
Factors associated with prognosis for survival and athletic use in foals with septic arthritis: 93 cases (1987-1994).
Journal of the American Veterinary Medical Association    October 8, 1999   Volume 215, Issue 7 973-977 
Steel CM, Hunt AR, Adams PL, Robertson ID, Chicken C, Yovich JV, Stick JA.To identify factors affecting the prognosis for survival and athletic use in foals with septic arthritis. Methods: Retrospective study. Methods: 93 foals with septic arthritis. Methods: Medical records were reviewed to obtain clinical findings, laboratory test results, radiographic findings, treatment method, and outcome. Race records for Thoroughbreds and Standardbreds were evaluated to determine whether foals subsequently raced and whether they raced successfully. Results: 43 foals had 1 affected joint, 44 foals had multiple affected joints, and number of affected joints was not recorded for...
Equine vision.
Equine veterinary journal    October 3, 1999   Volume 31, Issue 5 354-355 doi: 10.1111/j.2042-3306.1999.tb03832.x
Farrall H, Handscombe M.No abstract available
Clinical, haematological and biochemical findings in foals with neonatal Equine herpesvirus-1 infection compared with septic and premature foals.
Equine veterinary journal    October 3, 1999   Volume 31, Issue 5 422-426 doi: 10.1111/j.2042-3306.1999.tb03843.x
Perkins G, Ainsworth DM, Erb HN, Del Piero F, Miller M, Wilkins PA, Palmer J, Frazer M.A retrospective multicentre study comparing historical, clinical, haematological, acid-base and biochemical findings of foals with Equine herpesvirus-1 (EHV-1) infection, septicaemia or prematurity was performed to determine if early diagnosis of EHV-1 foals was possible. Fifty-three foals were studied and were assigned to one of 2 groups: herpes positive (n = 14) or herpes negative (n = 39). The latter group included 20 septic, 11 premature, and 8 premature and septic foals. The presence of herpes antigen was confirmed by immunoperoxidase histochemical staining of tissues from necropsied foal...
Supporting forelimb lameness: clinical judgement vs. computerised symmetry measurement.
Equine veterinary journal    October 3, 1999   Volume 31, Issue 5 417-421 doi: 10.1111/j.2042-3306.1999.tb03842.x
Peham C, Licka T, Girtler D, Scheidl M.The aim of this study was to compare supporting forelimb lameness determined by a motion analysis system with the subjective grading of a trained equine orthopaedic surgeon. Trotting on a treadmill, 29 individuals with a supporting forelimb lameness were measured with the SELSPOT II system and judged by the clinician. The vertical motion of the head was measured, analysed using Fourier transform, and the percentages of symmetry determined. The veterinarian evaluated the lameness and graded it according to a clinical routine. Veterinarian and system for motion analysis assigned the lameness to ...
Small intestine strangulation by components of the spermatic cord in two geldings.
Journal of the American Veterinary Medical Association    September 25, 1999   Volume 215, Issue 6 824-796 
Moll HD, Howard RD, May KA, Cheramie HS.Two adult Quarter Horse geldings were evaluated for signs of abdominal pain. Both horses had signs of depression and distended small intestines on abdominal palpation per rectum. Abdominal exploratory surgery was performed on both horses. In each instance, small intestine was found to be strangulated by components of the spermatic cord. Both horses were euthanatized because of a poor prognosis. Although not commonly observed, incarceration of intestine by components of the spermatic cord should be considered as a cause of small intestine strangulation in male horses. Early recognition of this ...