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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Thrombelastography in 26 healthy horses with and without activation by recombinant human tissue factor.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    August 21, 2009   Volume 19, Issue 1 96-101 doi: 10.1111/j.1476-4431.2008.00381.x
Epstein KL, Brainard BM, Lopes MA, Barton MH, Moore JN.To develop a standardized technique for thrombelastography (TEG) analysis in healthy adult horses, with and without the ex vivo addition of tissue factor (TF) as an activator. To determine reference intervals for TEG parameters in the horse, and to determine if traditional coagulation tests correlate with TEG. Methods: Prospective, observational. Methods: Veterinary teaching hospital. Methods: Twenty-six healthy adult horses. Methods: None. Results: Thrombelastography with (TF-TEG) and without (TEG) the addition of TF performed by 4 operators. Coagulation profiles (prothrombin time, activated ...
A technique for central venous pressure measurement in normal horses.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    August 21, 2009   Volume 19, Issue 3 241-246 doi: 10.1111/j.1476-4431.2009.00420.x
Wilsterman S, Hackett ES, Rao S, Hackett TB.To investigate a technique of central venous pressure (CVP) measurement using a newly developed catheter in healthy adult horses. Methods: Prospective experimental study. Methods: University research facility. Methods: Twenty healthy adult horses. Methods: An equine central venous catheter was inserted into the jugular vein to a length of approximately 80 cm from the mid-cervical region in an attempt to catheterize the pulmonary artery. Pulmonary arterial catheterization was confirmed by echocardiography. Insertion distance and pressure were measured at this location with a disposable manomete...
Evaluation of plasma fibrinogen concentration as an indicator of physeal or epiphyseal osteomyelitis in foals: 17 cases (2002-2007).
Journal of the American Veterinary Medical Association    August 18, 2009   Volume 235, Issue 4 415-419 doi: 10.2460/javma.235.4.415
Newquist JM, Baxter GM.To determine whether high plasma fibrinogen concentration (> or = 900 mg/dL) is a valid indicator of physeal or epiphyseal osteomyelitis in foals. Methods: Retrospective case series. Methods: 17 foals with physeal or epiphyseal osteomyelitis with or without septic arthritis, 17 foals with septic arthritis alone, 20 foals with non-Rhodococcus equi pneumonia, and 22 healthy foals. Methods: Medical records were reviewed for information regarding signalment and total WBC count, segmented neutrophil count, and plasma fibrinogen concentration measured when foals were initially evaluated at the ho...
A lateral approach to the repair of propagating fractures of the medial condyle of the third metacarpal and metatarsal bone in 18 racehorses.
Veterinary surgery : VS    August 14, 2009   Volume 38, Issue 6 689-695 doi: 10.1111/j.1532-950X.2009.00562.x
Wright IM, Smith MR.To report the technique, observations on fracture configurations and results of treatment by fixation lag screw following the fracture plane determined by an approach to the third metacarpal/metatarsal bone (MC3/MT3) that begins laterally over the metacarpo(metatarso)phalangeal joint and extends dorsally over the diaphysis of the bone. Methods: Case series. Methods: Thoroughbred horses (n=18) with propagating fractures of the medial condyle of MC3/MT3. Methods: Retrospective analysis of case records of horses with fractures of the medial condyle of MC3/MT3 that propagated sagittaly or in a spi...
Effect of transvenous electrical cardioversion on plasma cardiac troponin I concentrations in horses with atrial fibrillation.
Journal of veterinary internal medicine    August 11, 2009   Volume 23, Issue 5 1103-1107 doi: 10.1111/j.1939-1676.2009.0369.x
Jesty SA, Kraus MS, Gelzer AR, Rishniw M, Moise NS.Whether electrical cardioversion of cardiac arrhythmias results in cardiomyocyte damage is unknown. Objective: To describe effect of transvenous electrical cardioversion (TVEC) on plasma cardiac troponin I (cTnI) concentration in horses. Methods: All horses presented to the Cornell University Hospital for Animals for cardioversion of atrial fibrillation between May 2006 and October 2008 were eligible for inclusion in the study. Owners of 14 horses elected for TVEC and each horse was then enrolled (16 procedures). Methods: Prospective observational study measuring concentrations of plasma cTnI ...
Effects of different postmenopausal hormone therapy regimens on cerebral blood flow and cognitive functions.
Advances in therapy    August 11, 2009   Volume 26, Issue 8 805-811 doi: 10.1007/s12325-009-0058-x
Guvenal T, Durna A, Erden O, Guvenal F, Cetin M, Cetin A.The purpose of this study was to compare the effects of different postmenopausal hormone therapy regimens, namely conjugated equine estrogens (CEE), CEE plus medroxyprogesterone acetate (MPA), tibolone, and raloxifene on cerebral blood flow and cognitive functions. Methods: A total of 64 healthy postmenopausal women admitted to the Department of Obstetrics and Gynecology, Cumhuriyet University, Turkey were included in this study. Patients were divided into five groups with respect to the treatment protocols: CEE 0.625 mg/day (n=13); CEE 0.625 mg/day + MPA 2.5 mg/day (n=14); tibolone 2.5 mg/day...
Cloprostenol in equine reproductive practice: something more than a luteolytic drug.
Reproduction in domestic animals = Zuchthygiene    August 5, 2009   Volume 45, Issue 5 e8-e11 doi: 10.1111/j.1439-0531.2009.01508.x
Cuervo-Arango J, Newcombe JR.Prostaglandin F(2α) and its analogues (PGF) are widely used in equine reproductive practice. The interval from PGF treatment to ovulation (ITO) varies greatly with a range from 2 to 16 days. Clinical observation suggests that mares mated and ovulated soon after PGF treatment may have poor fertility. Reproductive records of 329 cyclic Thoroughbred mares were analysed retrospectively. The following parameters were analysed: (i) use of cloprostenol; (ii) ITO and (iii) number of ovulations per cycle. According to these parameters, mares were classified into four groups. (i) mares with spontaneous...
Molecular evidence for persistence of Anaplasma phagocytophilum in the absence of clinical abnormalities in horses after recovery from acute experimental infection.
Journal of veterinary internal medicine    August 4, 2009   Volume 23, Issue 3 636-642 doi: 10.1111/j.1939-1676.2009.0317.x
Franzén P, Aspan A, Egenvall A, Gunnarsson A, Karlstam E, Pringle J.Anaplasma phagocytophilum infects several mammalian species, and can persist in sheep, dogs, and calves. However, whether this organism persists in horses or induces long-term clinical abnormalities is not known. Objective: To evaluate whether A. phagocytophilum can persist in horses and to document clinical findings for 3 months after complete recovery from acute disease. Methods: Five clinically normal adult horses that had recovered spontaneously from experimentally induced acute disease caused by a Swedish equine isolate of A. phagocytophilum. Methods: Horses were monitored for up to 129 d...
Methods and reliability of tissue Doppler imaging for assessment of left ventricular radial wall motion in horses.
Journal of veterinary internal medicine    August 4, 2009   Volume 23, Issue 3 643-652 doi: 10.1111/j.1939-1676.2009.0287.x
Schwarzwald CC, Schober KE, Bonagura JD.Noninvasive assessment of left ventricular (LV) function is incompletely studied in horses. Objective: The goals of this study were to investigate the feasibility, techniques, and reliability of tissue Doppler imaging (TDI) for characterization of LV radial wall motion in healthy horses. Methods: Three Standardbreds, 3 Thoroughbreds; age 8-14 years; body weight 517-606 kg. Methods: Repeated echocardiographic examinations were performed by 2 observers in unsedated horses using TDI. Test reliability was determined by estimating measurement variability, within-day interobserver variability, and b...
Surgical management of complete diaphyseal third metacarpal and metatarsal bone fractures: clinical outcome in 10 mature horses and 11 foals.
Equine veterinary journal    August 1, 2009   Volume 41, Issue 5 465-473 doi: 10.2746/042516409x389388
Bischofberger AS, Fürst A, Auer J, Lischer C.Osteosynthesis of third metacarpal (McIII) and third metatarsal (MtIII) bone fractures in horses is a surgical challenge and complications surrounding the repair are common. Retrospective studies evaluating surgical repair, complications and outcome are necessary to increase knowledge and improve success of long bone fracture repair in the horse. Objective: To evaluate clinical findings, surgical repair, post operative complications and outcome of 10 mature horses and 11 foals with McIII or MtIII fractures that were treated with open reduction and internal fixation (ORIF). Methods: Medical rec...
The range and prevalence of pathological abnormalities associated with lameness in working horses from developing countries.
Equine veterinary journal    August 1, 2009   Volume 41, Issue 5 474-481 doi: 10.2746/042516409x373907
Broster CE, Burn CC, Barr AR, Whay HR.Lameness is highly prevalent in working horses, but published reports on the associated pathological abnormalities are lacking. With over 42 million horses in developing countries and the majority used for work, lameness has major welfare implications. Objective: To describe the range and prevalence of pathological abnormalities associated with lameness in working horses. Methods: A standard lameness assessment was adapted for field use in working equids. Data on pathological abnormalities and pain responses in the feet, limbs and spine were collected through observation, palpation, manipulati...
Two- and three-dimensional computed tomographic anatomy of the enamel, infundibulae and pulp of 126 equine cheek teeth. Part 1: Findings in teeth without macroscopic occlusal or computed tomographic lesions.
Equine veterinary journal    August 1, 2009   Volume 41, Issue 5 433-440 doi: 10.2746/042516409x390214
Windley Z, Weller R, Tremaine WH, Perkins JD.Dental disorders are of major clinical importance in equine practice; however, the knowledge of normal dental anatomy, especially that of the pulp remains incomplete. Computed tomography (CT) is being used increasingly in the diagnosis of dental disease, although the normal 2- (2D) and 3-dimensional (3D) CT anatomy has not yet been fully described. Objective: To describe the 2D and 3D CT appearance of the enamel, infundibulae and pulp of normal equine cheek teeth. Methods: One-hundred-and-twenty-six cadaveric cheek teeth with eruption ages of 0.5-19 years were evaluated; CT scans of each tooth...
Initial investigation of mortality rates and prognostic indicators in horses with colic in Israel: a retrospective study.
Equine veterinary journal    August 1, 2009   Volume 41, Issue 5 482-486 doi: 10.2746/042516409x391060
Sutton GA, Ertzman-Ginsburg R, Steinman A, Milgram J.Initial assessment of the mortality rates and prognostic indicators in horses with colic presented to a referral hospital in Israel. Objective: To determine mortality rates and to identify potential prognostic indicators in horses undergoing treatment for colic. Methods: The medical records of 208 colic cases were reviewed and mortality rates calculated including 95% confidence intervals. Mortality rates in surgical cases were calculated separately for strangulating and nonstrangulating lesions as well as for lesions of the large and small intestines. Potential prognostic indicators were ident...
Two- and three-dimensional computed tomographic anatomy of the enamel, infundibulae and pulp of 126 equine cheek teeth. Part 2: Findings in teeth with macroscopic occlusal or computed tomographic lesions.
Equine veterinary journal    August 1, 2009   Volume 41, Issue 5 441-447 doi: 10.2746/042516409x391033
Windley Z, Weller R, Tremaine WH, Perkins JD.Dental disease often presents a diagnostic challenge in the horse. Computed tomography (CT) is increasingly used in the evaluation of head related disease in the horse, but the CT appearance of the most common dental diseases of horses has not yet been fully described. Objective: To describe the CT appearance of the peripheral enamel, pulp, infundibular enamel and cement in equine cheek teeth with macroscopic occlusal or CT lesions. Methods: In this study, 126 cadaveric cheek teeth with eruption ages of between 05 and 19 years were evaluated for lesions of their infundibulae, pulp and enamel u...
Diaphragmatic hernia in horses: 44 cases (1986-2006).
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    July 28, 2009   Volume 19, Issue 4 357-362 doi: 10.1111/j.1476-4431.2009.00439.x
Hart SK, Brown JA.To present a case series of horses diagnosed with diaphragmatic hernia, and to determine the significance of (1) historical information, examination findings, and laboratory data; and (2) exploratory laparotomy or necropsy findings on short- and long-term outcome. Methods: University Referral Hospital. Methods: Retrospective study. Methods: Forty-four horses/foals admitted between 1986 and 2006 with a diagnosis of diaphragmatic hernia made either at exploratory laparotomy or necropsy. Methods: None. Results: Information from the medical records included history, clinical examination findings a...
Equine pericardium collagen wound dressing in the treatment of the neuropathic diabetic foot wound: a pilot study.
Journal of the American Podiatric Medical Association    July 17, 2009   Volume 99, Issue 4 301-305 doi: 10.7547/0980301
Fleischli JG, Laughlin TJ, Fleischli JW.Treatment of diabetic foot wounds remains a major health-care issue, with diabetic foot ulcers representing the most common causal pathway to lower-extremity amputation. Although several investigations have examined topical collagen-based dressings, none have specifically looked at equine pericardium. We, therefore, evaluated the effect of the equine pericardium dressing on neuropathic foot wounds. Methods: Twenty-three consecutive patients with 34 neuropathic foot wounds were evaluated as part of a pilot study. An equine pericardium dressing was applied in a standard manner, and the patients ...
Extra-adrenal paraganglioma of the equine orbit: six cases.
Veterinary ophthalmology    July 17, 2009   Volume 12, Issue 4 263-268 doi: 10.1111/j.1463-5224.2009.00706.x
Miesner T, Wilkie D, Gemensky-Metzler A, Weisbrode S, Colitz C.At The Ohio State University from 1994-2006 six of seven horses evaluated for primary orbital disease were diagnosed with extra-adrenal paraganglioma (EAPG). The horses ranged in age from 14 to 24 years, with a mean of 16.8 years. Duration of clinical signs was 1.5 years to 5 years, with a mean of 2.8 years. Clinical signs varied, but all six had non-painful exophthalmus of the right eye. Five horses had complete ocular exams reported; three of five had decreased to absent vision, two of five had pale optic nerves, and in three of five, difficulty of retropulsion of the globe was noted. Diagno...
Factors predictive of abnormal results for computed tomography of the head in horses affected by neurologic disorders: 57 cases (2001-2007).
Journal of the American Veterinary Medical Association    July 16, 2009   Volume 235, Issue 2 176-183 doi: 10.2460/javma.235.2.176
Sogaro-Robinson C, Lacombe VA, Reed SM, Balkrishnan R.To determine neurologic indications associated with abnormal results for computed tomography (CT) imaging of the head of horses affected by neurologic disorders. Methods: Retrospective case series. Methods: 57 horses. Methods: Signalment, history, clinical abnormalities, and clinicopathologic findings were obtained from medical records of horses examined because of neurologic disorders, and precontrast and postcontrast CT images of the head were reviewed. Data were analyzed by use of univariate and multivariate logistic regression. Results: For a horse with abnormal mentation, odds of having a...
Evaluation of the cranial cruciate ligament repair system(®) in surgery for laryngeal hemiplegia in heavy draft horses.
Journal of equine science    July 15, 2009   Volume 20, Issue 2 19-22 doi: 10.1294/jes.20.19
Sasaki N, Morita Y, Moriyama T, Yamada H.The purpose of this study was to evaluate the effect of the canine cranial cruciate ligament repair system on laryngeal hemiplegia in heavy draft horses. Twenty-four heavy draft horses diagnosed with grade 4 laryngeal hemiplegia were allocated to either the prosthetic laryngoplasty (PL) group (n=14) or a canine cranial cruciate ligament repair system (CCCLRS) group (n=10). Right to left angle quotients (RLQs) of abductions of the arytenoid cartilages were endoscopically evaluated before and after surgery. Post-operative RLQs in the CCCLRS group were significantly lower than those of the PL gro...
Parasitism and colic.
The Veterinary clinics of North America. Equine practice    July 8, 2009   Volume 25, Issue 2 233-245 doi: 10.1016/j.cveq.2009.04.003
Reinemeyer CR, Nielsen MK.Equids are hosts to dozens of species of internal parasites that infect no other domestic animals. Virtually all horses, especially those exposed to pasture, experience some level of parasitism continuously. Despite pathologic evidence of parasitic damage in various organs and tissues, few parasitisms are manifested systemically in well-managed horses. Contrary to conventional wisdom, only three common parasitisms of horses are likely to be manifested as colic: Strongylus vulgaris, Parascaris equorum, and Anoplocephala perfoliata. This article discusses the life cycles, pathophysiology, manife...
Laparoscopic mesh incisional hernioplasty in five horses.
Veterinary surgery : VS    July 4, 2009   Volume 38, Issue 3 318-325 doi: 10.1111/j.1532-950X.2009.00511.x
Caron JP, Mehler SJ.To report a technique for incisional hernioplasty in horses using laparoscopic placement of a prosthetic mesh. Methods: Case series. Methods: Horses (n=5) with ventral median abdominal incisional hernia. Methods: A telescope and 2 instrument portals were established bilaterally, lateral to and distant from the hernia margins. After exposure of the internal rectus sheath by removal of retroperitoneal fat with endoscopic scissors and monopolar cautery, a prosthetic mesh was introduced into the abdomen and secured intraperitoneally using transfascial sutures with or without supplemental endoscopi...
A description of the Tufts Cummings School of Veterinary Medicine-Massachusetts Equine Clinic combined equine medicine internship program.
Journal of the American Veterinary Medical Association    July 2, 2009   Volume 235, Issue 1 38-40 doi: 10.2460/javma.235.1.38
Mazan MR, Merriam J.No abstract available
Impaired intestinal absorption of glucose in 4 foals with Lawsonia intracellularis infection.
Journal of veterinary internal medicine    July 2, 2009   Volume 23, Issue 4 940-944 doi: 10.1111/j.1939-1676.2009.0334.x
Wong DM, Alcott CJ, Sponseller BA, Young JL, Sponseller BT.No abstract available
Peritoneal D-dimer concentration for assessing peritoneal fibrinolytic activity in horses with colic.
Journal of veterinary internal medicine    July 2, 2009   Volume 23, Issue 4 882-889 doi: 10.1111/j.1939-1676.2009.0344.x
Delgado MA, Monreal L, Armengou L, Ríos J, Segura D.Plasma D-dimer concentration is a useful marker to assess systemic coagulation and fibrinolytic activities in humans, dogs, and horses. Peritoneal fibrinolytic activity increases in horses with colic, especially in horses with endotoxin in the peritoneal fluid. Objective: Peritoneal D-dimer concentration can be used to assess peritoneal fibrinolytic activity in horses with severe gastrointestinal (GI) disorders and altered peritoneal fluid. Methods: Two hundred and twenty-one colic horses and 15 control horses. Methods: Prospective observational clinical study. Blood and peritoneal fluid were ...
Comparison of ultrasonography versus radiography for the diagnosis of dorsal fragmentation of the metacarpophalangeal or metatarsophalangeal joint in horses.
Journal of the American Veterinary Medical Association    July 2, 2009   Volume 235, Issue 1 70-75 doi: 10.2460/javma.235.1.70
Vanderperren K, Martens AM, Declercq J, Duchateau L, Saunders JH.To compare clinical usefulness of ultrasonography versus radiography for detection of fragmentation of the dorsal aspect of the metacarpophalangeal (MCP) and metatarsophalangeal (MTP) joints in horses. Methods: Cross-sectional study. Methods: 36 horses with fragmentation of the MCP (n = 19) and MTP (29) joints. Methods: In all joints, radiography (4 standard projections) and ultrasonography were performed prior to arthroscopic examination and fragment removal. Number and location of fragments identified radiographically and ultrasonographically were compared with arthroscopic findings. Results...
Magnetic resonance imaging findings of the lumbar spine in elite horseback riders: correlations with back pain, body mass index, trunk/leg-length coefficient, and riding discipline.
The American journal of sports medicine    July 2, 2009   Volume 37, Issue 11 2205-2213 doi: 10.1177/0363546509336927
Kraft CN, Pennekamp PH, Becker U, Young M, Diedrich O, Lüring C, von Falkenhausen M.Most orthopaedic problems experienced by competitive horseback riders are related to pain in the lower back, hip joint, and hamstring muscles. Riders-especially, show jumpers-are frequently hampered in their performance because of lumbar pain. To date, there has been no research into lumbar disk degeneration in elite competitive riders. Objective: Competitive horseback riding accelerates lumbar disk degeneration. Methods: Cross-sectional study; Level of evidence, 3. Methods: Fifty-eight elite riders (18 men, 40 women; mean age, 32.4 years) and a control group of 30 nonriding volunteers (17 men...
Case reports versus evidence-based medicine (EBM).
Equine veterinary journal    July 1, 2009   Volume 41, Issue 4 322-323 doi: 10.2746/042516409x429185
Rossdale PD.No abstract available
Clinical dental examinations of 357 donkeys in the UK. Part 1: prevalence of dental disorders.
Equine veterinary journal    July 1, 2009   Volume 41, Issue 4 390-394 doi: 10.2746/042516409x368912
du Toit N, Burden FA, Dixon PM.Dental disorders have a high prevalence in older donkeys and horses, but the nature and pathogenesis of many of these disorders have yet to be established. Objective: The identification and determination of the prevalence of important dental disorders in different age groups in a large single population of donkeys, to establish a better understanding of the nature and pathogenesis of these disorders. Methods: A prospective cross-sectional study was performed on the donkey population at The Donkey Sanctuary with detailed oral examinations of 357 donkeys within 7 different age groups (age range ...
Effect of magnitude and direction of force on laryngeal abduction: implications for the nerve-muscle pedicle graft technique.
Equine veterinary journal    July 1, 2009   Volume 41, Issue 4 328-333 doi: 10.2746/042516409x388208
Cramp P, Derksen FJ, Stick JA, de Feijter-Rupp H, Elvin NG, Hauptman J, Robinson NE.The nerve-muscle pedicle graft technique is a treatment for recurrent laryngeal neuropathy (RLN), but the optimal placement of the pedicles within the cricoarytenoideus dorsalis (CAD) muscle is unknown. Objective: The magnitude and direction of force placed on the muscular process of the left arytenoid cartilage affects the magnitude of laryngeal abduction. Methods: Five larynges were harvested from cadavers. Using increments of 0.98 N, a dead-weight force generator applied a force of 0-14.7 N for 1 min each to the left muscular process at 0, 10, 20, 30, 40, 50, 60 and 70 degrees angles. The r...
Clinical dental examinations of 357 donkeys in the UK. Part 2: epidemiological studies on the potential relationships between different dental disorders, and between dental disease and systemic disorders.
Equine veterinary journal    July 1, 2009   Volume 41, Issue 4 395-400 doi: 10.2746/042516409x368903
du Toit N, Burden FA, Dixon PM.Dental disease has been shown to be a risk factor for weight loss and colic in horses. No extensive clinical studies in donkeys have investigated the potential relationship between different dental disorders, or between dental disease and systemic disorders. Objective: To determine possible associations between dental disease and body condition score, weight loss, the need for supplemental feeding and prevalence of colic in donkeys of all ages, and to gain a better understanding of the pathogenesis of dental disease by the determination of associations between different dental disorders. Metho...
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