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Topic:Clinical Pathology
Clinical pathology in horses involves the study and analysis of biological samples to diagnose and monitor diseases and health conditions. This discipline encompasses various laboratory tests and procedures that assess the physiological and biochemical status of equines. Common analyses include hematology, biochemistry, urinalysis, and cytology, each providing insights into different aspects of equine health. Hematology evaluates blood components, such as red and white blood cells and platelets, to identify conditions like anemia or infection. Biochemistry tests measure enzymes, electrolytes, and metabolites to assess organ function and metabolic status. Urinalysis examines urine samples for indicators of renal function and systemic diseases. Cytology involves the microscopic examination of cells from tissues or fluids to detect abnormalities. This page aggregates peer-reviewed research studies and scholarly articles that explore the methodologies, applications, and diagnostic value of clinical pathology in equine medicine.
Study of the one-step growth curve of equine infectious anemia virus by immunofluorescence. Primary horse leukocyte cultures were inoculated with 2 or 10 50% tissue culture infective doses (TCID(50)) of equine infectious anemia (EIA) virus per cell, and the titer of cell-associated and fluid-phase virus was determined from 1 to 72 hr postinoculation (PI). Cover slips were collected from 4 to 72 hr PI and stained for EIA viral antigen by the indirect immunofluorescent (FA) technique. Viral replication was detected after a latent period of approximately 18 to 24 hr and reached peak titers of approximately 10(4.5) to 10(6) TCID(50)/0.5 ml from 48 to 72 hr PI. The fluid phase contained 1...
Cardiac pathology in the horse. 2. Microscopic pathology. The normal histology of cardiac tissues has been described by many authors, for example Gross and Kugel (1931), Trautmann and Fiebiger (1952), Gould (1968), Bloom and Fawcett (1969) and Ham (1969). In the horse, a few reports have described microscopic valvular pathology in detail (Ackerknecht 1923, Imre 1933, Ubach and Cler 1944). Experimentally induced lesions have been reported by Wadsworth (1919), Wadsworth and Sickles (1927) and Miller (1944), and endocarditis was described by Winqvist (1945) and Dobin (1959, 1968).
In 1966, Smetzer, Bishop and Smith outlined the valvular pathology ass...
Comparison of the effects of xylazine and acetylpromazine maleate in the horse. A 3-way Latin square design was used to compare the sedative and preanesthetic effects of xylazine given intravenously (i.v.) (1.1 mg./kg.) and given intramuscularly (i.m.) (2.2 mg./kg.) and acetylpromazine maleate (0.66 mg./kg.) given i.v. in the horse. Physiologic responses were recorded and clinical observations were made. Intravenous administration of xylazine and atropine sulphate (0.011 mg./kg.) appeared to have superior sedative properties, without having adverse effects on cardiovascular and respiratory systems. Both the i.v. and the i.m. administrations of xylazine prior to induction ...
