Omneity® Pellets
All-In-One Vitamin & Mineral Pellet
Topic:Clinical Study
Clinical studies in equine research involve the systematic investigation of health and disease in horses through structured scientific methods. These studies aim to evaluate the safety and efficacy of treatments, understand disease mechanisms, and improve veterinary care practices. Clinical studies can include randomized controlled trials, observational studies, and case-control studies. They may focus on various aspects such as pharmacokinetics, therapeutic interventions, and diagnostic techniques. This page compiles peer-reviewed research studies and scholarly articles that explore the design, implementation, and findings of clinical studies in equine medicine, providing insights into their impact on horse health and veterinary practices.
Effect of prostaglandin analogue on progesterone-treated pony mares during early pregnancy. Seven Welsh pony mares (9 pregnancies) received either 50 mg, 100 mg or 150 mg progesterone on alternate days, starting on day 21 of gestation. All but 2 pregnancies failed following prostaglandin administration on day 27. Although both mares were receiving the 150 mg progesterone dose rate, this treatment was not consistently successful in preventing pregnancy failure after prostaglandin administration.
Arteriography in ponies with Strongylus vulgaris arteritis. Radiographs of the aorta and abdominal arteries were obtained from a normal anesthetized pony following catheterization of a femoral artery for nonselective, semiselective or selective arteriography. The arteries had smooth borders and regular diameters and the branches of the cranial mesenteric artery could be followed distally on the angiogram through to the smaller branches proximal to the bowel wall. Following arteriography, the pony walked normally and there were minimal alterations of the levels of serum muscle enzymes and blood lactate. The procedures for arteriography were repeated in ...
Dysphagia resulting from unilateral rupture of the rectus capitis ventralis muscles in a horse. Dysphagia developed in a 2-year-old Quarter Horse filly following an incident in which it fell over backward while exercising on a mechanical horse walker. Hyperextension of the neck at this time apparently caused unilateral rupture of the longus capitis (rectus capitis ventralis major) and the rectus capitis ventralis minor muscles at their insertion. An existing mycotic lesion involving the dorsomedial wall of the left guttural pouch may have weakened the area of insertion of the involved muscles. Tearing of the tendinous insertion of these muscles caused damage to the IX, X, and XI cranial ...
Exercise studies in horses: 2. The cardiac response to exercise in normal horses and in horses with chronic obstructive pulmonary disease. The relationship of velocity (v) to heart rate (HR)and of kinetic energy (KE) to heart rate, were investigated in 6 normal horses and in 6 horses with chronic obstructive pulmonary, disease (COPD). Radiotelemetry was used to determine the heart rate while subjects were ridden on a 400m track. Velocity was measured by stop-watch between 2 markers 50 m apart at the end of the track. Kinetic energy was calculated from the formula KE =1/2 Mv2, where M = mass of horse, rider, saddle and bridle (KG) and V = velocity (metres per second). In all subjects, the relationship of velocity to heart rate was...
Laminitis in the horse. Much has been written on laminitis and its treatment over the past 200 years. This article makes a brief review of the practical essentials of the disease and considers some of the recent trends in therapy. Knowledge of the pathogenesis and aetiology of equine laminitis is still very incomplete but recent work in the United States by Coffman and his colleagues has been particularly productive.
Chromatographic determination of some corticosteroids, with special reference to horse doping. Some chromatographic procedures, which can be used to detect and determine certain corticosteroids in samples from race horses, are described. These procedures include thin-layer, gas and high pressure liquid chromatography.
Body position and mode of ventilation influences arterial pH, oxygen, and carbon dioxide tensions in halothane-anesthetized horses. Effects of body position and type of ventilation were determined on arterial blood gases (PaO2, PaCO2) and pH during and immediately following clinical halothane anesthesia in 36 young, physically conditioned horses. Horses in dorsal recumbency had a lower PaO2 than did similarly breathing horses in a lateral position. Predictably controlled positive-pressure ventilation inproved arterial oxygenation and permitted maintenance of a normal PaCO2. Most horses, regardless of type of ventilation and operative body positioning, were hypoxemic in the immediate postanesthetic period.
Corynebacterium equi enteritis in foals. Corynebacterium equi is a pathogen associated with respiratory disease in the foal. This paper discusses two cases of Corynebacterium equi infection, one acute and one chronic, in which the major damage was intestinal. Necrosis of Peyer's patches was the only lesion seen in the small intestine of both foals. The foal with acute disease had distinct green-tan focal necrosis and thickened mucosa of the large intestine. In the foal with chronic disease, the mucosa of the large intestine was thickened, rugose, and mottled red-tan. Histologically, the predominant lesions were villous atrophy, mucos...
An evaluation of ethyl-6-ethoxybenzothiazole-2-carbamate (Sch 18099) for anthelmintic activity in domestic animals. Ethyl-6-ethoxybenzothiazole-2-carbamate (Sch 18099) was evaluated for efficacy against natural helminth infections in ponies, pigs, lambs and chickens. Sixteen critical trials were conducted in ponies at dosages of 15 to 150 mg/kg. At 15 mg/kg, efficacy against adult and larval Oxyuris equi was 100% and 91% and against small strongyles it was 98%. Efficacy levels were 95% against Strongylus vulgaris and S. edentatus at the 20 mg/kg dosage. In two trials at 100 mg/kg efficacy against Parascaris equorum was 77%. No efficacy was observed against Gastrophilus spp. or Anoplocephala spp. In swine si...
Globidium leuckarti infection in a horse with diarrhoea. The history, clinical signs and post mortem findings in a case of Globidium leuckarti infection in a horse with chronic diarrhoea are described. The limited literature concerning this infection is reviewed, with particular reference to pathogenicity.
Guanidination of horse methemoglobin. Reaction of horse methemoglobin with O-methylisourea at pH 10.2 results in 95% conversion of lysine residues to homoarginine. Analysis of the chymotryptic peptides showed that no single ϵ-amino group was unreactive. Guanidination decreases the dependence of the sedimentation coefficient on hydrogen ion concentration in the range of pH 8 to 11 and did not affect the dependence on protein concentration at pH 7. These results support the conclusion that the lysine side chains involved in subunit contacts have sufficient freedom to accommodate the small changes in bulk and geometry associated wit...
Observations on small metacarpal and metatarsal fractures with or without associated suspensory desmitis in Standardbred horses. ALTHOUGH METACARPAL TI-IV and metatarsal II-IV (MC II-IV, MT II-IV) fractures are frequent in horses and surgical intervention routine, a review of the current literature revealed little information about this subject. The authors have found only two complete accounts of this problem (1, 6). The incidence of suspensory desmitis has been previously reported (3), but we find no previous correla-tion of MC II-IV, MT II-IV fractures with suspensory, desmitis. On these bases, a re-trospective study was conducted. At Purdue University from 1967 through 1974, 50 Standardbred horses underwent sur-gery...
