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Topic:Clinical Symptoms

Clinical symptoms in horses encompass a range of observable signs that may indicate underlying health issues, such as disease, injury, or physiological stress. These symptoms can vary widely depending on the condition and may include changes in behavior, appetite, respiratory patterns, or physical appearance. Common clinical symptoms in horses include lameness, colic, coughing, nasal discharge, and changes in body temperature or heart rate. Identifying and interpreting these symptoms is an essential aspect of equine veterinary practice, as they provide critical information for diagnosis and management of health conditions. This page compiles peer-reviewed research studies and scholarly articles that explore the identification, assessment, and implications of clinical symptoms in equine health management.
[Occurrance of antibodies against Leptospira in horses in Middle Germany].
Berliner und Munchener tierarztliche Wochenschrift    June 28, 2016   Volume 129, Issue 5-6 202-208 
Pikalo J, Sattler T, Eichinger M, Loitsch A, Sun H, Schmoll F, Schusser GF.Aim of the study was to detect antibodies and potential risk factors for an infec- tion with Leptospira in horses in Middle Germany. Serum samples of 314 horses were examined retrospectively by microscopic agglutination test for the presence of antibodies against eight Leptospira serovars. In total, 17.2% (n = 54) of the horses were positive for one or more of the serovars analyzed. The most prevalent serovar was lcterohaemorrhagiae (11.1%), followed by serovar Bratislava (9.6 %) and Grippotyphosa (1.9%). Mares showed a significantly higher occurrence of antibodies (p < 0.05) than geldings ...
Effects of repetition within trials and frequency of trial sessions on quantitative parameters of vertical force peak in horses with naturally occurring lameness.
American journal of veterinary research    June 28, 2016   Volume 77, Issue 7 756-765 doi: 10.2460/ajvr.77.7.756
Kaido M, Kilborne AH, Sizemore JL, Reisbig NA, Aarnes TK, Bertone AL.OBJECTIVE To analyze the effects of vertical force peak (VFP) of repition within trials and between trial sessions in horses with naturally occurring appendicular lameness. ANIMALS 20 lame horses acclimated to trotting over a force plate. PROCEDURES Kinetic gait data were collected by use of a force plate regarding affected and contralateral limbs of lame horses that completed 5 valid repetitions in each of 5 sessions performed at 0, 3, 6, 12, and 24 hours, constituting 1 trial/horse. Data were compared within and among repetitions and sessions, and factors influencing VFP values were identifi...
Pathology in Practice.
Journal of the American Veterinary Medical Association    June 17, 2016   Volume 249, Issue 1 59-62 doi: 10.2460/javma.249.1.59
Ernst ME, Weinstein N, Boes KM, Wilson KE, Gilsenan WF.No abstract available
Equine asthma: An appropriate, translational and comprehendible terminology?
Equine veterinary journal    June 14, 2016   Volume 48, Issue 4 403-405 doi: 10.1111/evj.12586
Pirie RS, Couëtil LL, Robinson NE, Lavoie JP.In their editorial in Equine Veterinary Journal (EVJ) almost a quarter of a century ago, Hall and Stark [1] referred to the inability of clinicians, both human and veterinary, to separate and recognise the different clinical entities responsible for chronic diseases of the airways, with the subsequent development of several different approaches to terminology, as well as treatment. In relation to equine nonseptic lower airway disease, and despite many attempts to identify the most appropriate nomenclature, this challenge remains as topical today as it did then. ‘Equine asthma’ has ...
Concurrent Equine Degenerative Myeloencephalopathy and Equine Motor Neuron Disease in Three Young Horses.
Journal of veterinary internal medicine    June 14, 2016   Volume 30, Issue 4 1344-1350 doi: 10.1111/jvim.13977
Finno CJ, Miller AD, Sisó S, Divers T, Gianino G, Barro MV, Valberg SJ.No abstract available
Analytical validation and establishment of reference intervals for a ‘high-sensitivity’ cardiac troponin-T assay in horses.
BMC veterinary research    June 13, 2016   Volume 12, Issue 1 104 doi: 10.1186/s12917-016-0737-1
Shields E, Seiden-Long I, Massie S, Passante S, Leguillette R.Cardiac troponin-I assays have been validated in horses.'High-sensitivity' cardiac troponin assays are now the standard in human cardiology. Objective: Appropriately validate the'high-sensitivity' cardiac Troponin-T (hscTnT) assay for clinical use in horses, establish reference intervals, determine the biological variation, and demonstrate assay utility in selected clinical cases. Methods: Analytical validation of the Roche hscTnT assay included within- and between-run precision, linear dose response, limit of quantitation (LoQ), stability, and comparison with cTn-I (iSTAT). Reference interval...
Pathology in Practice.
Journal of the American Veterinary Medical Association    June 9, 2016   Volume 248, Issue 12 1355-1357 doi: 10.2460/javma.248.12.1355
Froment R, Allano M, Chiasson A, Doré M, Gara-Boivin C.No abstract available
Pulmonary atresia with intact ventricular septum and hypoplastic right ventricle in an Arabian foal.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology    June 6, 2016   Volume 18, Issue 3 284-289 doi: 10.1016/j.jvc.2016.04.002
Krüger MU, Wünschmann A, Ward C, Stauthammer CD.Pulmonary atresia with intact ventricular septum, rudimentary tricuspid valve, hypoplastic right ventricle, and right-to-left atrial shunting were identified in a four-day-old, male Arabian foal with clinical signs of cyanotic heart disease. Pulmonary blood flow was apparently derived from a ductus arteriosus. Echocardiographic evaluation revealed the majority of cardiac abnormalities and also findings compatible with right-sided congestive heart failure. Congenital cardiac defects have a high incidence in this breed, and this is the first description of this combination of congenital cardiac ...
Bacteraemia before, during and after tooth extraction in horses in the absence of antimicrobial administration.
Equine veterinary journal    June 4, 2016   Volume 49, Issue 2 178-182 doi: 10.1111/evj.12581
Kern I, Bartmann CP, Verspohl J, Rohde J, Bienert-Zeit A.Transient bacteraemia can occur during tooth extraction in humans, and dogs and can lead to severe infectious sequelae. Several case reports describe distant site infections following equine tooth extraction, but the occurrence of bacteraemia during dental surgery has not been evaluated in the horse. Objective: To determine if transient bacteraemia occurs during tooth extraction in horses, describe isolated organisms and compare these with those found in the diseased teeth. Methods: Prospective, observational study. Methods: Blood was collected aseptically for blood culture before, during and ...
Equid herpesvirus 1 and rhodococcus equi coinfection in a foal with bronchointerstitial pneumonia.
The Journal of veterinary medical science    June 3, 2016   Volume 78, Issue 9 1511-1513 doi: 10.1292/jvms.16-0024
Perez-Ecija A, Mendoza FJ, Estepa JC, Bautista MJ, Pérez J.A 2-month-old foal with septic shock and severe respiratory distress was referred to the Veterinary Teaching Hospital. Due to poor prognosis, the foal was euthanized. Histopathology showed lesions suggestive of Rhodococcus equi infection associated with a diffuse interstitial infiltrate of foamy macrophages and syncytial cells presenting large acidophilic intranuclear inclusion bodies, fibrin exudates and hyaline membranes. Bacteriological examination from lung and respiratory exudates confirmed R. equi infection, whilst immunohistochemistry and PCR yielded a positive result for Equid herpesvi...
Removal of sialoliths using the intraoral approach in 15 horses.
The Canadian veterinary journal = La revue veterinaire canadienne    June 2, 2016   Volume 57, Issue 6 647-650 
Oreff GL, Shiraki R, Kelmer G.This study describes the use of an intraoral approach for sialolith removal in horses. All horses resumed their previous activity after surgery. Sialoliths were composed mainly of calcium carbonate, containing a nidus of plant material. The removal of sialoliths via an intraoral approach results in a high success rate with minimal complications. Cette étude décrit l’utilisation d’une approche intra-orale pour l’enlèvement des sialolithes chez les chevaux. Tous les chevaux ont repris leurs activités antérieures après la chirurgie. Les sialolithes étaient principalement composés d...
Confirmation of Elsey virus infection in a Queensland horse with mild neurologic signs. Agnihotri K, Pease B, Oakey J, Campbell G.In 2011, a 2-year-old horse in northern Queensland, Australia, was reported to have developed mild neurologic signs, and a blood sample was submitted for laboratory investigation. Virus isolation was performed using the blood sample, and an orbivirus was isolated. This was confirmed to be a strain of Elsey virus (ELSV) after transmission electron microscopy and nucleotide sequencing. The nucleotide sequence was compared with those in GenBank, and had 100% identity with ELSV previously reported from the Northern Territory, Australia. ELSV is taxonomically closely related to Peruvian horse sickn...
Effects of regional limb perfusion volume on concentrations of amikacin sulfate in synovial and interstitial fluid samples from anesthetized horses.
American journal of veterinary research    May 27, 2016   Volume 77, Issue 6 582-588 doi: 10.2460/ajvr.77.6.582
Godfrey JL, Hardy J, Cohen ND.OBJECTIVE To evaluate the effect of volume of IV regional limb perfusion (IVRLP) on amikacin concentrations in synovial and interstitial fluid of horses. ANIMALS 8 healthy adult horses. PROCEDURES Each forelimb was randomly assigned to receive IVRLP with 4 mL of amikacin sulfate solution (250 mg/mL) plus 56 mL (total volume, 60 mL) or 6 mL (total volume, 10 mL) of lactated Ringer solution. Horses were anesthetized, and baseline synovial and interstitial fluid samples were collected. A tourniquet was placed, and the assigned treatment was administered via the lateral palmar digital vein. Venous...
Extrinsic innervation of ileum and pelvic flexure of foals with ileocolonic aganglionosis.
Cell and tissue research    May 26, 2016   Volume 366, Issue 1 13-22 doi: 10.1007/s00441-016-2422-x
Giancola F, Gentilini F, Romagnoli N, Spadari A, Turba ME, Giunta M, Sadeghinezhad J, Sorteni C, Chiocchetti R.Equine ileocolonic aganglionosis, which is also called lethal white foal syndrome (LWFS), is a severe congenital condition characterized by the unsuccessful colonization of neural crest progenitors in the caudal part of the small intestine and the entire large intestine. LWFS, which is attributable to a mutation in the endothelin receptor B gene, is the horse equivalent of Hirschsprung's disease in humans. Affected foals suffer from aganglionosis or hypoganglionosis of the enteric ganglia resulting in intestinal akinesia and colic. In other species with aganglionosis, fibers of extrinsic origi...
Association of Presence of Band Cells and Toxic Neutrophils with Systemic Inflammatory Response Syndrome and Outcome in Horses with Acute Disease.
Journal of veterinary internal medicine    May 23, 2016   Volume 30, Issue 4 1284-1292 doi: 10.1111/jvim.13968
Lambert JL, Fernandez NJ, Roy MF.Band cells and toxic neutrophils are thought to indicate acute and severe systemic illness but no studies have investigated their importance in adult equine emergency admissions. Objective: The objective of this study was to evaluate the association of band cells and toxic neutrophils with systemic inflammatory response syndrome (SIRS) and outcome in horses. Methods: One hundred and five adult horses admitted on emergency basis to a private primary referral practice. Methods: Prospective observational study with sample collection. All horses admitted on emergency basis over the study period we...
Epidemiological and clinical aspects on West Nile virus, a globally emerging pathogen.
Infectious diseases (London, England)    May 20, 2016   Volume 48, Issue 8 571-586 doi: 10.3109/23744235.2016.1164890
David S, Abraham AM.Since the isolation of West Nile virus (WNV) in 1937, in Uganda, it has spread globally, causing significant morbidity and mortality. While birds serve as amplifier hosts, mosquitoes of the Culex genus function as vectors. Humans and horses are dead end hosts. The clinical manifestations of West Nile infection in humans range from asymptomatic illness to West Nile encephalitis. Methods: The laboratory offers an array of tests, the preferred method being detection of RNA and serum IgM for WNV, which, if detected, confirms the clinical diagnosis. Although no definitive antiviral therapy and vacc...
Reactive mesothelial hyperplasia associated with chronic peritonitis in a 20-year-old Quarter horse.
The Canadian veterinary journal = La revue veterinaire canadienne    May 7, 2016   Volume 57, Issue 5 492-496 
Hoon-Hanks LL, Rout ED, Vap LM, Aboellail TA, Hassel DM, Nout-Lomas YS.A 20-year-old gelding was diagnosed with peritonitis and severe reactive mesothelial hyperplasia. Exploratory laparotomy findings were suggestive of a neoplastic etiology; however, additional diagnostics ruled this out and the horse made a full recovery. This report demonstrates the difficulty and value of differentiating between reactive and neoplastic mesothelial processes. Une péritonite et l’hyperplasie mésothéliale réactive grave ont été diagnostiquées chez un hongre âgé de 20 ans. Les résultats d’une laparatomie exploratoire ont suggéré une étiologie néoplasique. Cepen...
IMAGING DIAGNOSIS-IDIOPATHIC HYOID MALFORMATION IN AN 8-YEAR-OLD WELSH SECTION D HORSE. Dixon J, Biggi M, O'Brien EJ, Farr R, Witte TH.An 8-year-old gelding was evaluated for intermittent dorsal displacement of the soft palate (DDSP) at exercise. Standing laterolateral radiographs demonstrated an abnormal crossed appearance of the stylohyoid bones. Computed tomography (CT) confirmed abnormal positioning of the left stylohyoid bone and articulations with both the left thyrohyoid and ceratohyoid bones. Surgical treatment consisted of combined left ceratohyoidectomy and thyrohyoidectomy. Postoperatively the patient's presenting complaint resolved completely, with the horse returning to full work. Standing laterolateral radiograp...
Pathology in Practice.
Journal of the American Veterinary Medical Association    May 3, 2016   Volume 248, Issue 10 1131-1133 doi: 10.2460/javma.248.10.1131
Tirosh-Levy S, Brener O, Aloisio F, Tatz AJ, Kelmer G.No abstract available
Double plate fixation for the management of proximal interphalangeal joint instability in 30 horses (1987-2015).
Equine veterinary journal    April 29, 2016   Volume 49, Issue 2 211-215 doi: 10.1111/evj.12578
McCormick JD, Watkins JP.Double plate fixation has been reported in a small number of horses with comminuted fractures of the middle phalanx. There are no published reports using this technique in the management of other injuries that destabilise the proximal interphalangeal joint (PIJ), including biaxial palmar/plantar eminence fractures and disruption of the palmar/plantar soft tissue support structures of the PIJ. Furthermore, there is a paucity of information on the long-term prognosis for horses undergoing double plate fixation to manage destabilising injuries of the PIJ. Objective: To document further the clinic...
Imiquimod treatment for Equus caballus papillomavirus infection in equine aural plaques.
Veterinary dermatology    April 24, 2016   Volume 27, Issue 3 175-e44 doi: 10.1111/vde.12305
Zakia LS, Olivo G, Basso RM, Mira J, Herman M, Araujo JP, Borges AS, Oliveira-Filho JP.Aural plaques are a dermatopathy associated with Equus caballus papillomavirus (EcPV). This disease affects horses of all ages, genders and breeds, and causes sensitivity of the ears. Objective: The aim of this study was to evaluate the clinical efficacy of 5% imiquimod cream for the treatment of aural plaques and to compare the PCR detection of EcPV 3, 4, 5 and 6 before and after treatment. Methods: Eight horses diagnosed with aural plaques (14 ears) were used. Three mares with unilateral aural plaques were used as untreated controls. Methods: Imiquimod cream was applied every 48 h until comp...
Malignant Glomus Tumour (Glomangiosarcoma) with Additional Neuroendocrine Differentiation in a Horse.
Journal of comparative pathology    April 18, 2016   Volume 154, Issue 4 309-313 doi: 10.1016/j.jcpa.2016.03.002
Peters M, Grafen J, Kuhnen C, Wohlsein P.A 13-year-old Icelandic crossbred horse was presented with headshaking and progressive impairment of chewing. A slowly growing mass was identified in the anterior maxilla. This was associated with lysis of the alveolar bone and the roots of the incisors and there were nodular proliferations affecting the nasal septum and conchae. There was no response to chemotherapy and so the horse was humanely destroyed. Based on morphological, immunohistochemical and ultrastructural findings the mass was classified as a malignant glomus tumour with multifocal vascular spaces and additional neuroendocrine d...
Cardiorespiratory and anesthetic effects of combined alfaxalone, butorphanol, and medetomidine in Thoroughbred horses.
Journal of equine science    April 12, 2016   Volume 27, Issue 1 7-11 doi: 10.1294/jes.27.7
Ohmura H, Okano A, Mukai K, Fukuda K, Takahashi T.This study evaluated induction of anesthesia and cardiorespiratory and anesthetic effects during maintained anesthesia with the combination of alfaxalone, medetomidine, and butorphanol. Alfaxalone (1.0 mg/kg) was administered to induce anesthesia after premedication with medetomidine (7.0 µg/kg), butorphanol (25 µg/kg), and midazolam (50 µg/kg) in six Thoroughbred horses. Intravenous general anesthesia was maintained with alfaxalone (2.0 mg/(kg∙hr)), medetomidine (5.0 µg/(kg∙hr)), and butorphanol (30 µg/(kg∙hr)) for 60 min. Electrical stimulation of the upper oral mucosa was used to...
Arthrodesis of the equine centrodistal and tarsometatarsal joints using a single modified kerf-cut cylinder.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    April 12, 2016   Volume 29, Issue 3 227-231 doi: 10.3415/VCOT-15-10-0167
Biedrzycki AH, Grant BD, Nemke B, Markel MD, Morello SL.To describe a technique for surgical placement of a modified kerf-cut cylinder for the purpose of arthrodesis across the equine centrodistal and tarsometatarsal joints. Methods: Each horse (n = 4) underwent unilateral placement of a single kerf-cut cylinder spanning the centrodistal and tarsometatarsal joints with the placement of an autologous cancellous bone graft. Horses were evaluated via lameness examination and radiography postoperatively and euthanatization of each horse was performed at four different time points up to 12 weeks post-surgery to evaluate for lameness, implant stability a...
Peri-anaesthetic complications in an equine referral hospital: Risk factors for post anaesthetic colic.
Equine veterinary journal    April 12, 2016   Volume 48, Issue 3 394 doi: 10.1111/evj.12567
Hughes KJ.No abstract available
Clinicopathological findings in horses with a bi- or tripartite navicular bone.
BMC veterinary research    April 9, 2016   Volume 12 74 doi: 10.1186/s12917-016-0698-4
van der Zaag EJ, Weerts EA, van den Belt AJ, Back W.Navicular bone partition is a rare condition reported in horses, which is during the evaluation of a lameness or prepurchase examination often misinterpreted for a parasagittal fracture. In this report, the clinicopathological findings of three cases of navicular bone partition are evaluated. The possible pathomechanisms underlying the condition are hypothesised, focusing on a potential origin of foetal vascular disturbance. This study is furthermore aiming at a clearer and earlier recognition of navicular bone partition, since this condition would finally predispose for a clinical lameness wi...
Phaeohyphomycosis due to Pyrenophora phaeocomes and Drechslera nobleae in an Appaloosa mare.
The Canadian veterinary journal = La revue veterinaire canadienne    April 5, 2016   Volume 57, Issue 4 431-433 
Jennings JE.A 21-year-old Appaloosa mare was presented with a pigmented cutaneous mass at the base of the right side of the neck. The diagnosis of phaeohyphomycosis due to pigmented fungi, known as Pyrenophora phaeocomes and Drechslera nobleae, was made based on a histopathology report followed by polymerase chain reaction (PCR) and 18S rRNA gene sequencing. The mass was surgically excised with clean margins, which is usually curative. Une jument Appaloosa âgée de 21 ans a été présentée avec une masse cutanée pigmentée à la base du côté droit du cou. Le diagnostic de phæohyphomycose causée p...
Magnetic resonance imaging features of progressive ethmoid hematoma in 2 horses.
Veterinaria italiana    April 2, 2016   Volume 52, Issue 1 31-35 doi: 10.12834/VetIt.259.889.2
Careddu GM, Evangelisti MA, Columbano N, Masala G, Manunta ML, Passino ES.Progressive ethmoid hematoma is frequently reported among the pathologies of the upper airways in horses. While several hypotheses have been proposed such as repeated trauma, inflammatory processes and/or chronic infections, congenital phenomena, complication of hemangiomas, and neoplastic processes, the aetiology of this condition is yet unknown. Clinical symptoms are non-specific and includes haemorrhagic nasal discharge, respiratory noise not related to physical exercise and, in most severe cases, phenomena of coughing. The purpose of this case report is to contribute to a correct diagnosti...
Nutritional management of the foal with diarrhoea.
Equine veterinary education    March 30, 2016   Volume 30, Issue 2 100-105 doi: 10.1111/eve.12564
Barr B.Diarrhoea is a common problem in the neonatal and suckling foal. In certain circumstances supplemental nutrition is necessary depending on the age of foal, severity of diarrhoea and presence of other systemic manifestations. Nutritional supplementation can be provided either enterally or parenterally. Enteral nutrition is superior to parenteral nutrition because it is the most natural and physiologically sound means to provide nutritional support. Parenteral nutrition may be warranted if the foal is unable to receive or tolerate enteral nutrition. Dextrose alone or with amino acids and lipids ...
Pain: Its Diagnosis and Management in the Rehabilitation of Horses.
The Veterinary clinics of North America. Equine practice    March 26, 2016   Volume 32, Issue 1 13-29 doi: 10.1016/j.cveq.2015.12.005
Daglish J, Mama KR.This article provides a brief overview of pain physiology and its relevance to equine patients. Objective and subjective techniques for assessing pain in the horse are described in depth. Pharmacologic and interventional pain modulation treatments are discussed with a focus on the rehabilitating horse.
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