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Topic:Clinical Symptoms

Clinical symptoms in horses encompass a range of observable signs that may indicate underlying health issues, such as disease, injury, or physiological stress. These symptoms can vary widely depending on the condition and may include changes in behavior, appetite, respiratory patterns, or physical appearance. Common clinical symptoms in horses include lameness, colic, coughing, nasal discharge, and changes in body temperature or heart rate. Identifying and interpreting these symptoms is an essential aspect of equine veterinary practice, as they provide critical information for diagnosis and management of health conditions. This page compiles peer-reviewed research studies and scholarly articles that explore the identification, assessment, and implications of clinical symptoms in equine health management.
The pharmacokinetics and pharmacodynamics of the injectable anaesthetic alfaxalone in the horse.
Veterinary anaesthesia and analgesia    August 13, 2011   Volume 38, Issue 5 431-438 doi: 10.1111/j.1467-2995.2011.00634.x
Goodwin WA, Keates HL, Pasloske K, Pearson M, Sauer B, Ranasinghe MG.To determine the pharmacokinetics and pharmacodynamics of the neurosteroidal anaesthetic, alfaxalone, in horses after a single intravenous (IV) injection of alfaxalone, following premedication with acepromazine, xylazine and guaiphenesin. Methods: Prospective experimental study. Methods: Ten (five male and five female), adult, healthy, Standardbred horses. Methods: Horses were premedicated with acepromazine (0.03 mg kg(-1) IV). Twenty minutes later they received xylazine (1 mg kg(-1) IV), then after 5 minutes, guaiphenesin (35 mg kg(-1) IV) followed immediately by IV induction of anaesthesia w...
Use of acetaminophen (paracetamol) as a short-term adjunctive analgesic in a laminitic pony.
Veterinary anaesthesia and analgesia    August 13, 2011   Volume 38, Issue 5 521-522 doi: 10.1111/j.1467-2995.2011.00639.x
West E, Bardell D, Morgan R, Senior M.No abstract available
Clinical and diagnostic imaging findings in horses with subchondral bone trauma of the sagittal groove of the proximal phalanx. Dyson S, Nagy A, Murray R.Eight sports horses with unilateral (4) or bilateral (3) forelimb or unilateral hindlimb (1) lameness had subtle radiologic abnormalities of the subchondral bone of the sagittal groove of the proximal phalanx associated with moderate or intense increased radiopharmaceutical uptake. High-field or low-field magnetic resonance (MR) imaging confirmed the presence of a fissure fracture or subchondral and trabecular bone trauma. Seven of eight lesions were located approximately midway between the dorsal and palmar cortices of the proximal phalanx; the eighth was sited more dorsally. Two horses under...
Persistent penile erection (priapism) after acepromazine premedication in a gelding.
Veterinary anaesthesia and analgesia    August 13, 2011   Volume 38, Issue 5 523-525 doi: 10.1111/j.1467-2995.2011.00641.x
Taylor AH, Bolt DM.No abstract available
Ultrasound-guided cervical centesis to obtain cerebrospinal fluid in the standing horse. Pease A, Behan A, Bohart G.Horses with intracranial lesions and severe ataxia are not good anesthesia candidates; however, only one method to obtain cerebrospinal fluid (CSF) from the cervical region in a standing horse has been reported. This method is not performed routinely due to the difficulty for sample acquisition. Our hypothesis is that standing cervical centesis can be performed in horses without complication. Ultrasound-guided centesis of the CSF between C1 and C2 in 11 clinically normal horses and two horses with neurologic signs were performed. Horses were sedated and ultrasound was used to identify the suba...
Review of seven cases of granulosa cell tumour of the equine ovary.
The Veterinary record    August 10, 2011   Volume 169, Issue 10 251 doi: 10.1136/vr.d4635
Crabtree J.This paper reviews the equine granulosa cell tumour (GCT) and describes the clinicopathological features, treatment and outcome in seven cases of GCT in mares. Mares were presented with unilateral ovarian enlargement during the 2007 to 2010 breeding seasons. The mean (sd) age of the mares was 11.7 (5.96) years. Three mares were multiparous barren, three were nulliparous and one was primigravida. Behaviour at presentation was 57 per cent anoestrus, 28 per cent with stallion-like behaviour and 14 per cent with persistent oestrus. All mares had unilateral ovarian enlargement. Six non-pregnant mar...
The clinical presentation and surgical treatment of verrucous dermatitis lesions in a draught horse.
Veterinary dermatology    August 9, 2011   Volume 23, Issue 1 71-e17 doi: 10.1111/j.1365-3164.2011.00997.x
Poore LA, Else RW, Licka TL.Verrucous pastern dermatitis is a progressive inflammatory skin disease commonly involving the palmar or plantar aspects of the pasterns of horses. There are no reports of successful surgical treatment for multifocal circumscribed verrucous masses in the chronic stages of verrucous pastern dermatitis. A combination of sharp dissection and electrocautery was used to resect numerous multifocal circumscribed verrucous masses from the distal hindlimb of an 11-year-old gelding draught horse. There was no evidence of significant regrowth or complications at a 24 month postoperative examination.
Amputation of finger by horse bite with complete avulsion of both flexor tendons.
Orthopedics    August 8, 2011   Volume 34, Issue 8 e421-e423 doi: 10.3928/01477447-20110627-26
Koren L, Stahl S, Rovitsky A, Peled E.Amputation of fingers with tendon avulsion occurs through a traction injury, and most occur through a ring avulsion mechanism. Usually the flexor digitorum profundus is torn out with the amputated finger. Replantation usually is recommended only when the amputation is distal to the flexor digitorum superficialis insertion. Animal bites are relatively common, with a decreasing order of frequency of dogs, cats, and humans. Horse bites are relatively infrequent but are associated with crush injuries and tissue loss when they occur. This article describes a 23-year-old man with amputation of his m...
Effect of general anesthesia on plasma cardiac troponin I concentrations in healthy horses.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology    August 6, 2011   Volume 13, Issue 3 163-169 doi: 10.1016/j.jvc.2011.04.005
Slack J, Boston R, Driessen B, Reef V.To evaluate the effect of general anesthesia on plasma cTnI concentrations in horses. Methods: Thirty-two horses undergoing general anesthesia and either elective surgery or MRI without surgery were prospectively studied. Twenty-nine horses (22 surgical, 7 imaging) completed the study. Plasma cTnI concentrations were determined prior to anesthesia and at 6, 12 and 24 h following discontinuation of the inhalant anesthetic. Results: All horses had cTnI values within the reference range at all time points. Six horses (21%) developed detectable cTnI 6 or 12 h following anesthesia. Risk factors f...
Nephrosplenic entrapment of the large colon in 142 horses (2000-2009): analysis of factors associated with decision of treatment and short-term survival.
Equine veterinary journal. Supplement    August 4, 2011   Issue 39 63-68 doi: 10.1111/j.2042-3306.2011.00376.x
Lindegaard C, Ekstrøm CT, Wulf SB, Vendelbo JM, Andersen PH.Previous studies indicate similar overall survival of horses with nephrosplenic entrapment of the large colon (NSE), regardless of treatment strategy. Short-term survival of a primarily conservative treatment strategy without rolling under general anaesthesia (GA) and a low proportion of surgical intervention as well as indicators of short-term nonsurvival has not been documented. Objective: To document short-term survival of horses with NSE treated in a university referral hospital with a low rate of surgical interventions and to determine factors associated with the decision of treatment and...
Ex vivo comparison of three hand sewn end-to-end anastomoses in normal equine jejunum.
Equine veterinary journal. Supplement    August 4, 2011   Issue 39 76-80 doi: 10.1111/j.2042-3306.2011.00423.x
Sherlock C, Lee W, Mueller PO, Eggleston R, Epstein K.Although single layer techniques are preferred in man and small animals for small intestinal end-to-end anastomoses, double layer techniques are more popular in equine surgery. This study was undertaken to evaluate the ex vivo characteristics of 2 single layer anastomoses in comparison to the traditionally performed double layer anastomosis in equine jejunum. Objective: To compare ex vivo: 1) construction time; 2) bursting pressure; and 3) lumen size reduction of 3 suture patterns (double layer simple continuous/Cushing pattern [2C]; single layer Lembert pattern [1L]; and single layer Cushing ...
In vitro validation of the lactose 13C-ureide breath test for equine orocaecal transit time measurement.
Equine veterinary journal. Supplement    August 4, 2011   Issue 39 42-48 doi: 10.1111/j.2042-3306.2011.00406.x
Sutton DG, Preston T, Love S.Validation of a reliable, noninvasive clinical test for quantification of equine orocaecal transit time (OCTT) is required. This would facilitate an evidence-based approach to investigation and treatment of equine small intestinal disorders. Objective: 1) Comparison of the lactose (13) C-ureide breath test (LUBT) with the hydrogen breath test (H(2) BT) for OCTT measurement. 2) Identification of the characteristics of gastrointestinal microbial glycosylureide hydrolase activity in vitro. 3) Production of an optimised protocol for the LUBT for in vivo measurement of equine OCTT. Objective: Signi...
Ultrasonographic evidence of colonic mesenteric vessels as an indicator of right dorsal displacement of the large colon in 13 horses.
Equine veterinary journal. Supplement    August 4, 2011   Issue 39 153-155 doi: 10.1111/j.2042-3306.2011.00418.x
Grenager NS, Durham MG.This report describes the use of ultrasound to diagnose right dorsal displacement of the large colon (RDDLC) in 13 horses prior to surgery. Horses had ultrasonographic examinations performed of the right lateroventral aspect of the abdomen upon admission to the hospital with a 2-5 MHz broadband curvilinear sector scanning transducer after alcohol was used to wet the hair. First, the caecal vessels were identified in the right flank and followed medially and cranially. Next, each intercostal space, from caudal to cranial, was scanned from dorsal to ventral evaluating for abnormally-located mese...
Equine paranasal sinus disease: a long-term study of 200 cases (1997-2009): ancillary diagnostic findings and involvement of the various sinus compartments.
Equine veterinary journal    August 4, 2011   Volume 44, Issue 3 267-271 doi: 10.1111/j.2042-3306.2011.00420.x
Dixon PM, Parkin TD, Collins N, Hawkes C, Townsend N, Tremaine WH, Fisher G, Ealey R, Barakzai SZ.There is a lack of objective information on the value of ancillary diagnostic techniques used to investigate equine sinus disease, and also on which sinus compartments are commonly affected in this disorder. Objective: To record the ancillary diagnostic findings used to investigate equine sinus disease and to document which compartments are affected. Methods: The clinical case records of 200 consecutive cases of sinus disease, including subacute (2 months' duration) primary (n = 37); dental (n = 40); traumatic (n = 13); sinus cyst (n = 26); sinus neoplasia (n = 10); dental related oromaxillary...
Ultrastructural changes in the equine colonic mucosa after ischaemia and reperfusion.
Equine veterinary journal. Supplement    August 4, 2011   Issue 39 8-15 doi: 10.1111/j.2042-3306.2011.00402.x
Grosche A, Morton AJ, Graham AS, Sanchez LC, Blikslager AT, Polyak MM, Freeman DE.Ultrastructural changes in the epithelium can provide information on early changes in barrier properties, repair and inflammation in equine colon after ischaemia and reperfusion (I/R). Objective: To describe the morphology and ultrastructure of the epithelium in equine large colonic mucosa after I/R, and the response of inflammatory cells to injury. Methods: Ischaemia was induced for 1 h followed by 4 h of reperfusion in a 40 cm segment of the pelvic flexure in 6 horses. Mucosal biopsies before and after ischaemia, and after 1, 2 and 4 h of reperfusion were fixed in glutaraldehyde/paraformalde...
Evaluation of a commercially available modified-live Streptococcus equi subsp equi vaccine in ponies.
American journal of veterinary research    August 2, 2011   Volume 72, Issue 8 1130-1138 doi: 10.2460/ajvr.72.8.1130
Borst LB, Patterson SK, Lanka S, Barger AM, Fredrickson RL, Maddox CW.To evaluate a commercially available modified-live Streptococcus equi subsp equi vaccine for safety and persistence in vaccinated ponies and to detect recombination or reversion events in the vaccine strain. Methods: 5 ponies that were 1.5 to 8 years old (group 1) and 4 ponies that were 6 months old (group 2). Methods: Ponies were vaccinated, with a subsequent booster vaccination 2 to 3 weeks later, and monitored for 50 days. At booster vaccination, an equal amount of a tetracycline-resistant wild-type strain of S equiwas administered. Recovery of all strains was performed by use of bacteriolo...
Endovascular aortic stent graft infection with Streptococcus equi: the first documented case.
Vascular    July 29, 2011   Volume 21, Issue 1 14-16 doi: 10.1258/vasc.2010.cr0258
Parmar J, Winterbottom A, Cooke F, Lever AM, Gaunt M.Streptococcus equi is a common equine infectious disease, but transmission to man is rare and confined to those who commonly come into close contact with horses. Similarly, prosthetic stent graft infection is a rare complication of endovascular aortic aneurysm repair. We describe the first reported case of aortic stent graft with S. equi occurring in a professional racehorse trainer. Clinical presentation, investigations, imaging and management of this case are described. In conclusion, clinicians should consider infection with rare organisms in patients with prosthetic implants who regularly ...
Distal border fragments and shape of the navicular bone: radiological evaluation in lame horses and horses free from lameness.
Equine veterinary journal    July 27, 2011   Volume 44, Issue 3 325-331 doi: 10.1111/j.2042-3306.2011.00429.x
Biggi M, Dyson S.The significance of distal border fragments of the navicular bone is not well understood. There are also no objective data about changes in thickness and proximal/distal extension of the palmar cortex of the navicular bone. Objective: To describe the distribution of distal border fragments and their association with other radiological abnormalities of the navicular bone and describe the shape of the navicular bone in sound horses and horses with foot-related lameness, including navicular pathology. Methods: Sound horses had radiographs acquired as part of a prepurchase examination. Lame horses...
Clinical evaluation of total intravenous anesthesia using a combination of propofol and medetomidine following anesthesia induction with medetomidine, guaifenesin and propofol for castration in Thoroughbred horses.
The Journal of veterinary medical science    July 26, 2011   Volume 73, Issue 12 1639-1643 doi: 10.1292/jvms.11-0153
Oku K, Kakizaki M, Ono K, Ohta M.Seven Thoroughbred horses were castrated under total intravenous anesthesia (TIVA) using propofol and medetomidine. After premedication with medetomidine (5.0 µg/kg, intravenously), anesthesia was induced with guaifenesin (100 mg/kg, intravenously) and propofol (3.0 mg/kg, intravenously) and maintained with constant rate infusions of medetomidine (0.05 µg/kg/min) and propofol (0.1 mg/kg/min). Quality of induction was judged excellent to good. Three horses showed insufficient anesthesia and received additional anesthetic. Arterial blood pressure changed within an acceptable range in all horse...
Systemic effects of a prolonged continuous infusion of ketamine in healthy horses.
Journal of veterinary internal medicine    July 22, 2011   Volume 25, Issue 5 1134-1137 doi: 10.1111/j.1939-1676.2011.0761.x
Elfenbein JR, Robertson SA, Corser AA, Urion RJ, Sanchez LC.Ketamine as continuous rate infusion (CRI) provides analgesia in hospitalized horses. Objective: Determine effects of prolonged CRI of ketamine on gastrointestinal transit time, fecal weight, vital parameters, gastrointestinal borborygmi, and behavior scores in healthy adult horses. Methods: Seven adult Thoroughbred or Thoroughbred cross horses, with permanently implanted gastric cannulae. Methods: Nonblinded trial. Random assignment to 1 of 2 crossover designed treatments. Ketamine (0.55 mg/kg IV over 15 minutes followed by 1.2 mg/kg/h) or lactated Ringer's solution (50 mL IV over 15 minutes ...
Hogweed suspected of causing primary photosensitisation in a horse.
The Veterinary record    July 19, 2011   Volume 169, Issue 3 81-82 doi: 10.1136/vr.d4472
Ivens P.No abstract available
Congenital bilateral choanal stenosis in a warmblood foal.
The Veterinary record    July 16, 2011   Volume 169, Issue 9 232b doi: 10.1136/vr.d4202
Bienert-Zeit A, Ohnesorge B.No abstract available
Clinical signs of equine influenza in a closed population of horses at a 3-day event in southern Queensland, Australia.
Australian veterinary journal    July 8, 2011   Volume 89 Suppl 1 17-18 doi: 10.1111/j.1751-0813.2011.00729.x
Dups JN, Morton JM, Anthony ND, Dwyer JF.This report describes the clinical signs of equine influenza (EI) during an epidemic in a closed, predominantly immunologically naïve population of horses. It included 254 study horses, few of which exhibited all three signs of pyrexia, nasal discharge and cough simultaneously. We conclude that although the majority of affected horses exhibit temperature patterns resembling those most often described in the published literature, clinicians should be aware that other profiles are quite common.
Clinical evaluation of an end-tidal target-controlled infusion closed-loop system for isoflurane administration in horses undergoing surgical procedures.
Veterinary journal (London, England : 1997)    July 8, 2011   Volume 192, Issue 2 206-211 doi: 10.1016/j.tvjl.2011.06.001
Franci P, Bertamini A, Bertamini O, Pilla T, Busetto R.A new volatile anaesthetic agent delivery system was tested in 15 horses undergoing scheduled surgical procedures. The delivery system consisted of a laptop computer (with dedicated software), a computer-controlled syringe driver (loaded with liquid isoflurane) connected to the inspiratory arm of a large-animal circle breathing system and a respiratory gas monitor, providing isoflurane end-tidal concentrations (ET(measured)) every 20 s to the computer. Following induction and connection to the breathing system, mechanical ventilation was started. The bodyweight (BW), fresh gas flow, breathing ...
Diagnosis of equine influenza virus infections in quarantine stations in Australia, 2007.
Australian veterinary journal    July 8, 2011   Volume 89 Suppl 1 4-6 doi: 10.1111/j.1751-0813.2011.00722.x
Watson J, Selleck P, Axell A, Bruce K, Taylor T, Heine H, Daniels P, Jeggo M.In August 2007, several horses showed pyrexia and respiratory signs while in post-arrival quarantine in Australia. Subsequent investigations diagnosed equine influenza by serology and PCR in two quarantine stations. A common origin in a shipment of horses from Japan was indicated.
Severe combined immunodeficiency in a Caspian filly.
Journal of veterinary internal medicine    July 7, 2011   Volume 25, Issue 4 954-958 doi: 10.1111/j.1939-1676.2011.0746.x
Larson J, Buechner-Maxwell V, Crisman MV, LeRoith T, Witonsky S.No abstract available
Premature lactation and retention of a mummified fetus with live birth of the co-twin in a primiparous Morgan mare.
The Canadian veterinary journal = La revue veterinaire canadienne    July 7, 2011   Volume 52, Issue 4 423-425 
Robinson KA, Manning ST.This report describes a primiparous 8-year-old Morgan mare, which displayed premature lactation that began at approximately 240 d of gestation and lasted approximately 4 wk. The premature lactation resolved spontaneously, and the pregnancy was subsequently carried to full term with the delivery of a live foal and a mummified fetus. Lactation prématurée et rétention d’un fœtus momifié avec naissance vivante du jumeau chez une jument Morgan primipare. Ce rapport décrit une jument Morgan primipare âgée de 8 ans, qui a manifesté une lactation prématurée qui a commencé vers 240 jours ...
Chronic intestinal pseudo-obstruction in a horse: a case of myenteric ganglionitis.
The Canadian veterinary journal = La revue veterinaire canadienne    July 7, 2011   Volume 52, Issue 4 419-422 
Chénier S, Macieira SM, Sylvestre D, Jean D.An 11-year-old Quarter horse mare was presented for recurrent episodes of colic. A chronic intestinal pseudo-obstruction was diagnosed. Medical treatment and surgical resection of the colon were performed but the condition did not improve and the horse was euthanized. Histopathological examination revealed a myenteric ganglionitis of the small intestine and ascending colon. Une jument Quarter Horse âgée de 11 ans a été présentée pour coliques récurrentes. Une pseudo-obstruction intestinale chronique a été diagnostiquée. Le traitement médical et la résection chirurgicale du côlon ...
Lumbar ligamentum flavum hematoma treated with endoscopy.
Orthopedics    July 7, 2011   Volume 34, Issue 7 e324-e327 doi: 10.3928/01477447-20110526-27
Ohba T, Ebata S, Ando T, Ichikawa J, Clinton D, Haro H.Hematoma of the ligamentum flavum is a rare cause of neural compression, for which treatment has consisted of excising the hematoma via open surgical approaches, including total laminectomy or bilateral partial laminectomy. This article presents the first report of a microscope-assisted endoscopic decompression to resect a hematoma of the ligamentum flavum.A 52-year-old man presented with back and leg pain, as well as difficulty initiating micturation. Magnetic resonance imaging demonstrated an epidural mass at L5/S1 that was continuous with the facet joint. Visualization was obtained via an e...
Assessment of a bone biopsy technique for measuring tiludronate in horses: a preliminary study. Delguste C, Doucet M, Gabriel A, Guyonnet J, Lepage OM, Amory H.This study assessed the feasibility of measuring tiludronate in horses using a minimally invasive bone biopsy technique. Eight horses were treated with intravenous (IV) tiludronate [1 mg/kg bodyweight (BW)], either once (n = 4) or twice, 28 d apart (n = 4). The horses that were treated once were euthanized on days 1, 43, 57, or 92 and those that were treated twice, were euthanized on days 112, 154, 194, or 364. Bone samples were taken bilaterally from each horse at 4 sites: the third metacarpal bone (MCIII), the 13th rib (R13), the tuber coxae (TC), and the cuboid bone (CB). Test samples were ...
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