Analyze Diet

Topic:Disease Treatment

Disease treatment in horses encompasses a range of medical interventions and management strategies aimed at addressing various health conditions affecting equine species. These treatments can include pharmacological approaches, such as the administration of antibiotics, anti-inflammatory drugs, and antiparasitic medications, as well as non-pharmacological methods like physical therapy, dietary adjustments, and surgical procedures. The selection of appropriate treatments depends on the specific disease, its severity, and the individual needs of the horse. This topic brings together peer-reviewed research studies and scholarly articles that explore the efficacy, safety, and advancements in therapeutic options for equine diseases, providing insights into best practices and emerging trends in equine veterinary medicine.
Helminths in horses: use of selective treatment for the control of strongyles.
Journal of the South African Veterinary Association    January 5, 2005   Volume 75, Issue 3 129-136 doi: 10.4102/jsava.v75i3.468
Matthee S, McGeoch MA.The current level of anthelmintic resistance in the horse-breeding industry is extremely high and therefore more emphasis is being placed on studies that focus on the judicious use of anthelmintic products. The aims of the study were to: 1) establish if there is variation in the egg excretion pattern of strongyles between the different age classes of Thoroughbred horses in the Western Cape Province (WCP), 2) test if a selective treatment approach successfully reduces the number of anthelmintic treatments and maintains acceptably low helminth burdens in adult Thoroughbred horses, and 3) evaluat...
Treatment of tracheal collapse with an intraluminal stent in a miniature horse.
Journal of the American Veterinary Medical Association    January 1, 2005   Volume 225, Issue 11 1727-1702 doi: 10.2460/javma.2004.225.1727
Couëtil LL, Gallatin LL, Blevins W, Khadra I.A 7-month-old miniature horse was referred for respiratory distress. Tracheal collapse at the level of the thoracic inlet was diagnosed. An intraluminal nitinol stent was placed with endoscopic guidance. Respiratory function was restored immediately after stent placement. The main complication observed during a 14-month follow-up period was growth of granulation tissue through the stent, which was controlled satisfactorily by electrocautery performed during endoscopy with the horse standing. Treatment of tracheal collapse with an intraluminal stent is an effective, practical, and minimally inv...
Effects of treatment with and without adjuvant radiation therapy on recurrence of ocular and adnexal squamous cell carcinoma in horses: 157 cases (1985-2002).
Journal of the American Veterinary Medical Association    January 1, 2005   Volume 225, Issue 11 1733-1738 doi: 10.2460/javma.2004.225.1733
Mosunic CB, Moore PA, Carmicheal KP, Chandler MJ, Vidyashankar A, Zhao Y, Roberts RE, Dietrich UM.To determine the effects of treatment with and without adjuvant radiation therapy on recurrence of ocular and adnexal squamous cell carcinoma (SCC) at specific anatomic locations in horses. Methods: Retrospective study. Methods: 91 horses. Methods: Medical records of horses with histologically confirmed ocular and adnexal SCC evaluated from 1985 to 2002 were reviewed. Sex, breed, age, type of treatment, location, and recurrence of SCC were recorded. Two treatment groups determined by recurrence of SCCs treated with and without adjuvant radiation therapy were established. Results: The anatomic ...
Back problems and lameness in horses.
The Veterinary record    December 30, 2004   Volume 155, Issue 23 751-752 
Verheyen K, Wood J.No abstract available
[Latex agglutination system for the rapid diagnosis of leptospirosis in Cuba].
Revista panamericana de salud publica = Pan American journal of public health    December 24, 2004   Volume 16, Issue 4 259-265 doi: 10.1590/s1020-49892004001000005
Obregón AM, Fernández C, Rodríguez I, Balbis Y, Martínez B, Rodríguez J.To assess the sensitivity, specificity, reproducibility, and stability of five latex agglutination systems for detecting antibodies against leptospira in human and animal sera, by using the Leptospira serotypes that are most widely prevalent in Cuba. Methods: We performed an analytic and descriptive study with 706 human sera (65 tested positive for antibodies against leptospira with microagglutination (MAT) and hemagglutination (HA) techniques; 156 sera that tested negative with MAT and HA); 485 sera from 424 patients who had clinical or epidemiologic signs of leptospirosis; and 29 animal sera...
Repeated intraarticular injections of triamcinolone acetonide alter cartilage matrix metabolism measured by biomarkers in synovial fluid.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society    December 21, 2004   Volume 23, Issue 3 602-610 doi: 10.1016/j.orthres.2004.10.003
Céleste C, Ionescu M, Robin Poole A, Laverty S.Although intraarticular (IA) corticosteroids are frequently used to treat joint disease, the effects of their repeated use on articular cartilage remains controversial. The aim of our study was to determine the effects of a clinically recommended dose of IA triamcinolone acetonide (TA), on synovial fluid (SF) biomarkers of cartilage metabolism. Ten adult horses, free of osteoarthritis (OA) in their radiocarpal joints, were studied. One radiocarpal joint of each horse was randomly chosen for treatment and the contralateral anatomically paired joint acted as the control. Aseptic arthrocentesis w...
Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society    December 21, 2004   Volume 23, Issue 1 118-126 doi: 10.1016/j.orthres.2004.06.020
Haupt JL, Frisbie DD, McIlwraith CW, Robbins PD, Ghivizzani S, Evans CH, Nixon AJ.This study evaluated the potential of gene induced synoviocyte expression of a combination of insulin-like growth factor-I (AdIGF-I) and interleukin-1 receptor antagonist protein (AdIL-1Ra) to control articular cartilage degradation in vitro. Cartilage explants and synovial membrane were harvested from young mature horses. Synovial monolayers were established and either (1) maintained as untransduced controls; (2) transduced with AdIGF-I at 200 MOI in 500 microl serum-free medium; (3) transduced with AdIL-1Ra at 100 MOI; or (4) transduced with a combination of AdIGF-I (200 MOI) and AdIL-1Ra (1...
Local utilization of metacresolsulfonic acid combined with streptomycin in the treatment of actinomycosis.
Annals of the New York Academy of Sciences    December 18, 2004   Volume 1026 273-276 doi: 10.1196/annals.1307.042
Silva LA, Fioravanti MC, Oliveira KS, Atayde IB, Andrade MA, Jayme VS, Rabelo RE, Romani AF, Araújo EG.The effectiveness of combining metacresolsufonic acid with streptomycin in the treatment of actinomycosis, diagnosed either clinically or in the laboratory, was evaluated in 12 bovines and 2 equines. Eighty-seven percent of treated animals were considered clinically cured and did not show any signs of relapse after a six-month follow-up period. Therapeutic diagnosis by clinical observation was the procedure of choice when it was not possible to obtain laboratory diagnosis.
Specificity of serum neutralizing antibodies induced by transient immune suppression of inapparent carrier ponies infected with a neutralization-resistant equine infectious anemia virus envelope strain.
The Journal of general virology    December 18, 2004   Volume 86, Issue Pt 1 139-149 doi: 10.1099/vir.0.80374-0
Howe L, Craigo JK, Issel CJ, Montelaro RC.It has been previously reported that transient corticosteroid immune suppression of ponies experimentally infected with a highly neutralization resistant envelope variant of equine infectious anemia virus (EIAV), designated EIAV(DeltaPND), resulted in the appearance of type-specific serum antibodies to the infecting EIAV(DeltaPND) virus. The current study was designed to determine if this induction of serum neutralizing antibodies was associated with changes in the specificity of envelope determinants targeted by serum antibodies or caused by changes in the nature of the antibodies targeted to...
Eastern equine encephalitis: case report and literature review.
Medicine and health, Rhode Island    December 17, 2004   Volume 82, Issue 1 23-26 
Tabamo RE, Donahue JE.No abstract available
Reduction of twin pregnancy in the mare by transvaginal ultrasound-guided aspiration.
Reproduction in domestic animals = Zuchthygiene    December 16, 2004   Volume 39, Issue 6 434-437 doi: 10.1111/j.1439-0531.2004.00536.x
Mari G, Iacono E, Merlo B, Castagnetti C.Diagnosis and management of twin pregnancies in the mare are an ongoing challenge in equine reproduction. Early detection of twin and manual crush of one vesicle are the main steps in the management of twins. Few studies were carried out about the use of transvaginal ultrasound-guided aspiration (TUGA) for reduction of twins in the mare. In this study, the efficiency of TUGA for management of twin pregnancies was investigated. Reduction of unicornuate twins between 16 and 25 days of gestation gave a success rate of 70.0% (14 viable foals/20 twin pregnancies); when reduction was performed after...
Pemphigus foliaceus in the horse: a retrospective study of 20 cases.
Veterinary dermatology    December 9, 2004   Volume 15, Issue 6 381-388 doi: 10.1111/j.1365-3164.2004.00423.x
Vandenabeele SI, White SD, Affolter VK, Kass PH, Ihrke PJ.Twenty horses with pemphigus foliaceus were seen over a period of 15 years in a veterinary medical teaching hospital. Breeds seen were seven quarterhorses, five thoroughbreds, three cross-bred horses, two Arabians and one of each of the following: standardbred, Tennessee walker and warmblood. There was no breed, age or sex predisposition. Nine were mares, ten were geldings and one was a stallion. Ages ranged from 2.5 months to 25 years, with a mean of 8.6 years. Sixteen (80%) of the pemphigus foliaceus horses first exhibited signs between September and February. There was a statistically signi...
Ultrasonographic control of navicular bursa injection.
Equine veterinary journal    December 8, 2004   Volume 36, Issue 7 637-639 doi: 10.2746/0425164044864534
Spriet M, David F, Rossier Y.No abstract available
Diagnosis of dorsal displacement of the soft palate by sound spectrum analysis; the way ahead?
Equine veterinary journal    December 8, 2004   Volume 36, Issue 7 554-555 doi: 10.2746/0425164044864499
Dixon PM, Holcombe SJ.No abstract available
Equine dentistry–what do we really know?
Journal of veterinary dentistry    December 8, 2004   Volume 21, Issue 3 134-135 
Carmalt JL, Carmalt KP.No abstract available
Use of intravenous flecainide in horses with naturally-occurring atrial fibrillation.
Equine veterinary journal    December 8, 2004   Volume 36, Issue 7 609-614 doi: 10.2746/0425164044864516
van Loon G, Blissitt KJ, Keen JA, Young LE.It has been reported that i.v. flecainide has a high efficacy for the treatment of experimentally-induced acute atrial fibrillation (AF) in horses and that its use is associated with minimal toxic side effects. Objective: The objectives were to study the efficacy of i.v. flecainide as a treatment for atrial fibrillation in horses with naturally-occurring AF. Methods: Ten horses with naturally-occurring AF were treated with 2 mg/kg bwt flecainide i.v. at a rate of 0.2 mg/kg bwt/min. In 3 horses, the infusion was continued at 0.05-0.10 mg/kg bwt/min until a total dose of 3.0 mg/kg bwt had been a...
Surgical repair of rib fractures in 14 neonatal foals: case selection, surgical technique and results.
Equine veterinary journal    December 8, 2004   Volume 36, Issue 7 557-562 doi: 10.2746/0425164044864561
Bellezzo F, Hunt RJ, Provost R, Bain FT, Kirker-Head C.Fractured ribs are encountered quite frequently in newborn Thoroughbred foals, often with fatal outcome. Surgical repair of fractures therefore requires consideration as a means of reducing mortality. Objective: To evaluate the repair of rib fractures using internal fixation techniques in foals at 2 different equine hospitals following similar diagnostics and case selection. Methods: The records of 14 foals that underwent internal fixation of fracture ribs were reviewed. Subject details, clinical presentation, diagnosis, surgical technique, post operative care and complications were recorded. ...
Respiratory and metabolic effects of massive administration of isotonic saline solution in heaves-affected and control horses.
Equine veterinary journal    December 8, 2004   Volume 36, Issue 7 628-633 doi: 10.2746/0425164044864570
Jean D, Vrins A, Lavoie JP.It has been suggested that rapid administration of isotonic saline solution relieves airway obstruction in heaves-affected horses, but the efficacy and tolerability of this treatment is poorly documented. Objective: To determine the respiratory and metabolic effects of a rapid administration of isotonic saline solution in control horses and those with heaves. Methods: Thirty litres isotonic saline solution were administered i.v. to 5 control (Group C) and 9 heaves-affected horses (Group H). Pulmonary function testing and arterial blood gas analysis were performed prior to saline infusion, at 9...
Evaluation of cutaneous analgesia after non-focused extracorporeal shock wave application over the 3rd metacarpal bone in horses.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire    December 8, 2004   Volume 68, Issue 4 288-292 
Bolt DM, Burba DJ, Hubert JD, Pettifer GR, Hosgood GL.Extracorporeal shock wave therapy is becoming increasingly used in equine practice to treat musculoskeletal disorders. Although the exact effects of extracorporeal shock waves on tissues still need to be elucidated, transient cutaneous analgesia has been observed within treated areas in humans and horses. The purpose of this study was to determine the onset, magnitude, and duration of cutaneous analgesia after non-focused extracorporeal shock wave (ESW) application by comparing the limb withdrawal reflex latency (LWRL) in treated and untreated areas on the metacarpus of horses, using a focused...
Tegaserod (HTF 919) stimulates gut motility in normal horses.
Equine veterinary journal    December 8, 2004   Volume 36, Issue 7 622-627 doi: 10.2746/0425164044864543
Lippold BS, Hildebrand J, Straub R.It has been shown that the selective 5-HT4 receptor agonist tegaserod induces an increase in frequency and amplitude of contractions in isolated muscle preparations of equine ileum and pelvic flexure. Objective: To investigate the effects of tegaserod on gut motility and transit of spheres in normal horses. Methods: Six mature Freiberger horses were kept under standardised conditions. Effects of tegaserod (0.02 mg/kg bwt i.v. b.i.d. for 2 days) or vehicle on intestinal transit of barium-filled spheres, defaecation and gut sounds were studied in a cross-over design. Spheres were given via stoma...
Anticomplementary activity of equine whole IgG antivenoms: comparison of three fractionation protocols.
Toxicon : official journal of the International Society on Toxinology    December 8, 2004   Volume 45, Issue 1 123-128 doi: 10.1016/j.toxicon.2004.07.025
León G, Lomonte B, Gutiérrez JM.Early adverse reactions occur in a number of patients treated with heterologous antivenoms and have been associated with anticomplementary activity (ACA). In order to reduce the ACA of equine whole IgG antivenoms produced by caprylic acid fractionation, three different fractionation protocols were compared: (a) routine caprylic acid fractionation; (b) caprylic acid fractionation followed by beta-propiolactone treatment; and (c) caprylic acid fractionation followed by ion-exchange chromatography using a quaternary ammonium membrane. The three protocols yielded products with similar physicochemi...
Testing for equine arteritis virus.
The Veterinary record    December 3, 2004   Volume 155, Issue 20 647-648 
Cullinane AA.No abstract available
A lag-screw technique for bridging of the medial aspect of the distal tibial physis in horses.
Journal of the American Veterinary Medical Association    December 1, 2004   Volume 225, Issue 10 1581-1548 doi: 10.2460/javma.2004.225.1581
Witte S, Thorpe PE, Hunt RJ, Spirito MA, Rodgerson DH.A lag-screw technique for transphyseal bridging of the medial aspect of the distal tibial physis in foals with tarsal valgus deformities and results of the technique in 11 foals (6 with bilateral tarsal valgus deformities and 5 with unilateral tarsal valgus deformities) are described. Briefly, horses were anesthetized, and a single stab incision was made through the skin to the underlying bone over the most distal aspect of the medial malleolus. A 20-gauge needle was placed in the incision to guide screw placement, and a lag screw was inserted parallel to the medial cortex of the tibia under r...
Perinatal asphyxia syndrome in the foal: review and a case report.
Irish veterinary journal    December 1, 2004   Volume 57, Issue 12 707-714 doi: 10.1186/2046-0481-57-12-707
Galvin N, Collins D.: This report presented a brief overview of the literature on the perinatal asphyxia syndrome (PAS) in foals as a prelude to a description of the investigation and treatment of acute onset seizures in a 24-hour-old Thoroughbred colt foal.PAS can cause a wide variety of clinical abnormalities, of which seizures due to encephalopathy are the most significant. The structural and biochemical components of CNS neurones are disrupted by the shift from oxidative to anaerobic metabolism, with a resultant deficit in cellular energy. The cells succumb to the combined effects of acidosis, neurotoxic acti...
Does the cytotoxic effect of transient amyloid oligomers from common equine lysozyme in vitro imply innate amyloid toxicity?
The Journal of biological chemistry    December 1, 2004   Volume 280, Issue 8 6269-6275 doi: 10.1074/jbc.M407273200
Malisauskas M, Ostman J, Darinskas A, Zamotin V, Liutkevicius E, Lundgren E, Morozova-Roche LA.In amyloid diseases, it is not evident which protein aggregates induce cell death via specific molecular mechanisms and which cause damage because of their mass accumulation and mechanical properties. We showed that equine lysozyme assembles into soluble amyloid oligomers and protofilaments at pH 2.0 and 4.5, 57 degrees C. They bind thioflavin-T and Congo red similar to common amyloid structures, and their morphology was monitored by atomic force microscopy. Molecular volume evaluation from microscopic measurements allowed us to identify distinct types of oligomers, ranging from tetramer to oc...
Assessment of the efficacy of a single dose of a recombinant vaccine against West Nile virus in response to natural challenge with West Nile virus-infected mosquitoes in horses.
American journal of veterinary research    November 30, 2004   Volume 65, Issue 11 1459-1462 doi: 10.2460/ajvr.2004.65.1459
Siger L, Bowen RA, Karaca K, Murray MJ, Gordy PW, Loosmore SM, Audonnet JC, Nordgren RM, Minke JM.To determine the onset of immunity after IM administration of a single dose of a recombinant canarypox virus vaccine against West Nile virus (WNV) in horses in a blind challenge trial. Methods: 20 mixed-breed horses. Methods: Horses with no prior exposure to WNV were randomly assigned to 1 of 2 groups (10 horses/group). In 1 group, a recombinant canarypox virus vaccine against WNV was administered to each horse once (day 0). The other 10 control horses were untreated. On day 26, 9 treated and 10 control horses were challenged via the bites of mosquitoes (Aedes albopictus) infected with WNV. Cl...
Pharmacokinetic-pharmacodynamic relationships and dose response to meloxicam in horses with induced arthritis in the right carpal joint.
American journal of veterinary research    November 30, 2004   Volume 65, Issue 11 1533-1541 doi: 10.2460/ajvr.2004.65.1533
Toutain PL, Cester CC.To determine pharmacokinetic-pharmacodynamic (PK-PD) relationships and dose effects for meloxicam in horses and to propose a suitable dosage for use in clinical studies. Methods: 6 adult horses. Methods: The study was conducted by use of a randomized, Latin-square design. Arthritis was induced in the right carpal joint of each horse by administration of Freund's complete adjuvant. Various dosages of meloxicam (0, 0.25, 0.5, 1.0, and 2.0 mg/kg, IV) were then administered. Validated endpoints including stride length and overall clinical lameness score (scale of 0 to 20) were used to assess the e...
Effects of phenylbutazone, indomethacin, prostaglandin E2, butyrate, and glutamine on restitution of oxidant-injured right dorsal colon of horses in vitro.
American journal of veterinary research    November 30, 2004   Volume 65, Issue 11 1589-1595 doi: 10.2460/ajvr.2004.65.1589
Rötting AK, Freeman DE, Constable PD, Eurell JA, Wallig MA.To study the effects of phenylbutazone, indomethacin, prostaglandin E2 (PGE2), glutamine, and butyrate on restitution of oxidant-injured right dorsal colon of horses in vitro. Methods: Right dorsal colon from 9 adult horses euthanatized for reasons other than gastrointestinal tract disease. Methods: Mucosal segments from the right dorsal colon were injured via exposure to HOCl and incubated in Ussing chambers in solutions containing phenylbutazone, indomethacin, indomethacin and PGE2, glutamine, and butyrate. Transepithelial resistance and mucosal permeability to mannitol were measured, and al...
Preferential and non-selective cyclooxygenase inhibitors reduce inflammation during lipopolysaccharide-induced synovitis.
Research in veterinary science    November 27, 2004   Volume 78, Issue 2 189-192 doi: 10.1016/j.rvsc.2004.07.006
Morton AJ, Campbell NB, Gayle JM, Redding WR, Blikslager AT.Synovitis in horses is frequently treated by administration of non-steroidal anti-inflammatory drugs (NSAIDs), which inhibit cyclooxygenase isoforms (COX-1 and COX-2). Constitutively expressed COX-1 is involved in physiologic functions such as maintenance of gastric mucosal integrity, whereas COX-2 is up-regulated at sites of inflammation. Thus, COX-2 inhibitors reduce inflammation with reduced gastrointestinal side effects as compared to non-selective COX inhibitors. The objective of the present study was to compare the anti-inflammatory effects of the preferential COX-2 inhibitor etodolac wi...
Carpal bursitis associated with Brucella abortus in a horse in Nigeria.
The Veterinary record    November 24, 2004   Volume 155, Issue 18 566-567 doi: 10.1136/vr.155.18.566
Ocholi RA, Bertu WJ, Kwaga JK, Ajogi I, Bale JO, Okpara J.No abstract available