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Topic:Disease

The study of diseases in horses encompasses a wide range of conditions affecting equine health, including infectious diseases, metabolic disorders, and genetic abnormalities. These diseases can impact various systems within the horse, such as respiratory, gastrointestinal, and musculoskeletal systems, and can lead to significant health challenges. Research in this area focuses on understanding the pathophysiology, diagnosis, prevention, and treatment of equine diseases. Common diseases studied include equine influenza, equine herpesvirus, and laminitis. This page provides access to peer-reviewed research studies and scholarly articles that explore the etiology, clinical presentation, and management strategies of diseases in horses, contributing to the advancement of equine veterinary medicine.
An investigation into alternative methods for the serodiagnosis of dourine.
The Onderstepoort journal of veterinary research    June 1, 1988   Volume 55, Issue 2 117-119 
Williamson CC, Stoltsz WH, Mattheus A, Schiele GJ.The complement fixation test (CFT), indirect fluorescent antibody test (IFAT), card agglutination test for trypanosomiasis (CATT) and enzyme-linked immunosorbent assay (ELISA) were compared in their application to the serological diagnosis of Trypanosoma equiperdum infection in 43 horses. The CFT remains a reliable test for dourine, especially in countries where other members of the subgenus Trypanozoon do not occur. The IFAT is a good 'back-up' test, but, requiring skilled operators it has the disadvantage of making it labour intensive, and interpretation of results subjective. This makes it ...
Immune-mediated polysynovitis in four foals.
Journal of the American Veterinary Medical Association    June 1, 1988   Volume 192, Issue 11 1581-1584 
Madison JB, Scarratt WK.The deposition of immune complexes in the synovial membrane resulted in polysynovitis in 4 foals. All 4 foals had an infection at a site other than the joints. The polysynovitis was characterized by marked effusions of affected joints and joint stiffness. Bacterial and mycoplasmal cultures of the joints did not yield growth. Staining of synovial membrane biopsy specimens with fluorescein-labeled anti-equine IgG revealed immune complexes in the synovial membrane. Immune-mediated polysynovitis might develop in foals with bacterial infections. We propose that deposition of immunoglobulin in the s...
Endotoxaemia in racehorses following exertion.
Journal of the South African Veterinary Association    June 1, 1988   Volume 59, Issue 2 63-66 
Baker B, Gaffin SL, Wells M, Wessels BC, Brock-Utne JG.Endotoxins (lipopolysaccharides-LPS) and anti-endotoxin IgG antibodies were measured in racehorses before and after races of 1,000, 2,000 and 2,800 m. Results show that the mean plasma concentration of endotoxin increased significantly (p less than 0.02) while the anti-LPS IgG concentration decreased significantly (p less than 0.005) in all horses following the races. Pre-race and post-race anti-LPS IgG levels in racing-fit racehorses were significantly higher than in untrained horses (p less than 0.05). The possibility therefore exists that training-induced stress leads to leakage of LPS into...
[Efficacy of pyrantel pamoate (Strongid) in the treatment of anoplocephalids in the horse].
Schweizer Archiv fur Tierheilkunde    June 1, 1988   Volume 130, Issue 6 321-328 
Gauderon H, Kipfer H, Hofer B, Pfister K.No abstract available
Protection against experimental infection with influenza virus A/equine/Miami/63 (H3N8) provided by inactivated whole virus vaccines containing homologous virus.
Epidemiology and infection    June 1, 1988   Volume 100, Issue 3 501-510 doi: 10.1017/s0950268800067236
Mumford JA, Wood JM, Folkers C, Schild GC.Thirty-one ponies immunized with inactivated virus vaccine containing A/equine/Miami/63 (H3N8) virus and six seronegative ponies were experimentally challenged with the homologous virus strain. All 6 unvaccinated ponies and 11 out of 31 vaccinated ponies became infected. A clear relationship between pre-challenge antibody, measured by single radial haemolysis (SRH), and protection was demonstrated as judged by virus excretion, febrile responses and antibody responses. Those ponies with SRH antibody levels greater than 74 mm2 were completely protected against challenge infection by the intranas...
Nonsurgical management of ruptured urinary bladder in a critically ill foal.
Journal of the American Veterinary Medical Association    June 1, 1988   Volume 192, Issue 11 1577-1580 
Lavoie JP, Harnagel SH.A small tear in the urinary bladder of a severely debilitated 4-day-old foal was managed with an indwelling urinary catheter connected to a urine collecting system. Fluid therapy, parenteral nutrition, and antimicrobial agents were used during the initial management of the ruptured bladder. Aseptic technique for catheter care and systemic administration of antimicrobial agents prevented the development of bacterial cystitis. Catheter management required constant monitoring, but the bladder defect was sealed within 5 days. Fungal arthritis caused by Candida tropicalis, immune-mediated anemia, d...
Osteoma of paranasal sinuses of a horse.
Journal of the American Veterinary Medical Association    May 15, 1988   Volume 192, Issue 10 1449-1450 
Schumacher J, Smith BL, Morgan SJ.A 2-year-old Quarter Horse gelding was examined for torticollis, facial protuberances over the frontal and maxillary sinuses, and persistent nasal discharge unresponsive to antibiotics. Radiograph revealed an osseous mass in the right paranasal sinuses. Histologic examination of the biopsied mass led to a diagnosis of osteoma. The mass was removed surgically in sections from the right frontal and maxillary sinuses through separate bone flaps, and sinuses were irrigated with saline solution for 8 days after surgery. Two weeks after surgery, radiography revealed small osseous opacities in the ri...
Cyclical accumulation of uterine fluid in mares with lowered resistance to endometritis.
The Veterinary record    May 14, 1988   Volume 122, Issue 20 489-490 doi: 10.1136/vr.122.20.489
Allen WE, Pycock JF.No abstract available
Rectal prolapse in a foaling mare.
The Veterinary record    May 7, 1988   Volume 122, Issue 19 471-472 doi: 10.1136/vr.122.19.471
Blythman WG.No abstract available
Lipoprotein (a) and plasminogen are immunochemically related.
Biochimica et biophysica acta    May 2, 1988   Volume 960, Issue 1 91-97 doi: 10.1016/0005-2760(88)90013-6
Karàdi I, Kostner GM, Gries A, Nimpf J, Romics L, Malle E.Earlier studies demonstrated that lipoprotein (a), a lipoprotein of high atherogenicity, possesses proteolytic activity. In this report, we provide evidence that the lipoprotein (a)-specific antigen, apoprotein (a) is immunochemically related to plasminogen. This was demonstrated by polyclonal antisera from rabbit, sheep and horse, and with three monoclonal antibodies from mouse. Using immunospecific adsorbers against lipoprotein (a), all plasminogen could be adsorbed from lipoprotein (a)-positive and apparently lipoprotein (a)-negative plasma. As an additional similarity to plasminogen, lipop...
Clearance of bromosulphthalein from plasma as a measure of hepatic function in normal horses and in horses with liver disease.
Research in veterinary science    May 1, 1988   Volume 44, Issue 3 343-348 
West HJ.Single intravenous injections of bromosulphthalein (BSP) were given to horses and the change in plasma concentration of BSP with time was analysed by computer to obtain the proportionality transfer constants 'a', 'h' and 'b'. No age, weight or sex differences in BSP clearance were found in normal horses. The technique was non-invasive, repeatable and suitable for conscious animals. The measurement of the transfer constants 'a', 'h' and 'b', helped to provide an accurate guide to diagnosis and prognosis of liver disease.
Isolation of Brucella suis biotype 1 from a horse.
Australian veterinary journal    May 1, 1988   Volume 65, Issue 5 162-163 doi: 10.1111/j.1751-0813.1988.tb14452.x
Cook DR, Kingston GC.No abstract available
Prevalence of piroplasmosis in equines in the Colombian province of Cordoba.
Tropical animal health and production    May 1, 1988   Volume 20, Issue 2 93-98 doi: 10.1007/BF02242234
Tenter AM, Otte MJ, Gonzalez CA, Abuabara Y.Eighty-two equine sera from 13 farms in northern Colombia were examined for antibodies to Babesia caballi and B. equi using the complement fixation (CF) and the indirect fluorescent antibody (IFA) test. Seroreactors to both piroplasms were present on all farms. The IFA test indicated a prevalence of 90% for B. caballi and 94% for B. equi. The CF test detected antibodies to B. caballi in 41% and to B. equi in 65% of the animals. The prevalence of seroreactors in different age groups revealed a significant decline in CF antibodies to B. caballi in animals older than three years. IFA titres for b...
Surgical treatment of acquired inguinal hernia in the horse: a review of 51 cases.
Equine veterinary journal    May 1, 1988   Volume 20, Issue 3 173-177 doi: 10.1111/j.2042-3306.1988.tb01491.x
van der Velden MA.During a seven year period, 51 cases of acquired inguinal herniation in 50 stallions were treated surgically. In 25 cases the herniated loop was ileal, in the other 26 it was jejunal. In cases of strangulation, the vaginal ring was enlarged by incising the peritoneum and transverse fascia. Closure of the superficial inguinal ring was advisable to prevent the hernia recurring. In all cases unilateral castration was performed. Laparotomy was carried out in 33 cases; 22 required intestinal resection and in four cases a bypass was made. Follow-up at least six months postoperatively indicated that ...
A case of atlanto-occipital arthropathy following guttural pouch mycosis in a horse. The use of radioisotope bone scanning as an aid to diagnosis.
Equine veterinary journal    May 1, 1988   Volume 20, Issue 3 219-220 doi: 10.1111/j.2042-3306.1988.tb01504.x
Walmsley JP.No abstract available
Kinetics of gentamicin elimination in two horses with acute renal failure.
Equine veterinary journal    May 1, 1988   Volume 20, Issue 3 182-184 doi: 10.1111/j.2042-3306.1988.tb01494.x
Sweeney RW, MacDonald M, Hall J, Divers TJ, Sweeney CR.No abstract available
Electrohydraulic lithotripsy for the treatment of cystic calculus in two geldings.
Equine veterinary journal    May 1, 1988   Volume 20, Issue 3 221-223 doi: 10.1111/j.2042-3306.1988.tb01505.x
Eustace RA, Hunt JM, Brearley MJ.No abstract available
ADCC and complement-dependent lysis as immune mechanisms against EHV-1 infection in the horse.
Research in veterinary science    May 1, 1988   Volume 44, Issue 3 295-302 
Stokes A, Wardley RC.Immunity to equine herpesvirus type 1 (EHV-1) was evaluated using sera collected from yearling horses involved in a trial of a commercial vaccine. Measurement of the ability of these sera to mediate antibody-dependent cellular cytotoxicity and complement-dependent lysis revealed that these mechanisms, although potentially important in recovery from EHV-1 infection, do not play a role in protection following vaccination.
Respiratory disease of horses associated with Mycoplasma infection.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B    May 1, 1988   Volume 35, Issue 4 264-270 doi: 10.1111/j.1439-0450.1988.tb00496.x
Antal T, Szabó I, Antal V, Vajda G, Polner A, Totth B, Szołlár I, Stipkovits L.No abstract available
Ruptured inguinal hernia in new-born colt foals: a review of 14 cases.
Equine veterinary journal    May 1, 1988   Volume 20, Issue 3 178-181 doi: 10.1111/j.2042-3306.1988.tb01492.x
van der Velden MA.Over a six year period, 14 new-born colt foals were treated surgically because of ruptured inguinal hernia. In all cases, the prolapsed intestines, which were jejunal loops, were situated subcutaneously and protruded through a rent in the parietal vaginal tunic at the level of the inguinal canal. After herniorrhaphy and unilateral castration, the prolapsed loops were replaced into the abdomen, and the superficial inguinal ring closed. Seven foals survived.
Ovarian strangulation as a cause of small colon obstruction in a foal.
Equine veterinary journal    May 1, 1988   Volume 20, Issue 3 217-218 doi: 10.1111/j.2042-3306.1988.tb01503.x
Evard JH, Fischer AT, Greenwood LD.No abstract available
Angular limb deformities in foals.
Equine veterinary journal    May 1, 1988   Volume 20, Issue 3 225-228 doi: 10.1111/j.2042-3306.1988.tb01508.x
Caron JP.No abstract available
Increased local IgA production in chronic obstructive pulmonary disease.
Equine veterinary journal    May 1, 1988   Volume 20, Issue 3 214-216 doi: 10.1111/j.2042-3306.1988.tb01502.x
Mair TS, Stokes CR, Bourne FJ.The immunoglobulin (Ig) content of serum and tracheal lavage fluid was measured in 50 horses suffering from chronic obstructive pulmonary disease (COPD) and 40 control horses. The mean immunoglobulin: albumin ratios of the lavage fluids of both groups were significantly higher than the corresponding values for serum, which indicates significant local production of immunoglobulins in the lower respiratory tract. The IgA: albumin ratio of lavage fluid was significantly higher in diseased compared with normal horses, which implies increased local production of IgA in this disease. The IgG: albumi...
Effect of exogenous ovarian steroids on the uterine luminal prostaglandins in ovariectomised mares with experimental endometritis.
Research in veterinary science    May 1, 1988   Volume 44, Issue 3 361-365 
Watson ED, Stokes CR, Bourne FJ.Prostaglandins (PGs) F and E2 were measured in lavage fluid from the uterus of ovariectomised mares after experimental induction of uterine inflammation. Treatment with progesterone alone, or progesterone followed by oestradiol, significantly increased the concentrations of these PGs in the lavage compared with mares treated with oestradiol or control mares. Ovarian steroids, therefore, influenced uterine PG synthesis in response to an inflammatory stimulus. To determine whether the uterine lavage procedure might contribute to the concentrations of prostaglandins in the lavage, the procedure w...
Procoagulant activity in respiratory tract secretions from horses with chronic pulmonary disease.
American journal of veterinary research    May 1, 1988   Volume 49, Issue 5 705-709 
Grünig G, Hermann M, Winder C, Von Fellenberg R.Cell-free supernatants (sol phases), obtained after centrifugation (50,000 x g for 45 minutes) of respiratory tract secretions from horses with chronic pulmonary disease, were assayed for procoagulant activity (PCA) in a one-stage clotting assay. Of the 103 specimens tested, 59% (61) contained PCA. Procoagulant activity was detected most often in respiratory tract secretions of severely affected horses and was correlated with the quantity of neutrophils in the respiratory tract secretions. In 12 of the 17 secretions tested, the clotting time was decreased in a dose-dependent manner. However, i...
Adverse reactions to equine vaccinations: a preliminary survey.
The Veterinary record    April 16, 1988   Volume 122, Issue 16 396 doi: 10.1136/vr.122.16.396
Mair TS.No abstract available
Exercise-induced pulmonary hemorrhage in horses.
Journal of the American Veterinary Medical Association    April 15, 1988   Volume 192, Issue 8 1012 
Brewer NR.No abstract available
Embryonic loss in pony mares induced by intrauterine infusion of Candida parapsilosis.
Theriogenology    April 1, 1988   Volume 29, Issue 4 835-847 doi: 10.1016/0093-691x(88)90220-8
Ball BA, Shin SJ, Patten VH, Garcia MC, Woods GL.Pony mares which were detected pregnant by transrectal ultrasonography received a single intrauterine infusion of either sterile saline (control, n = 12 mares) or 10(6)Candida parapsilosis (treated, n = 12 mares) between Days 11 to 14 postovulation. Subsequent embryonic loss was studied by daily ultrasonography of the mare's uterus, by serum progesterone levels, by endometrial swabs for cytologic and microbiologic examination and by endometrial biopsies that were taken after embryonic loss was detected. Significantly fewer (P<0.01) embryonic losses occurred in control than in treated mares (4 ...
High-frequency jet ventilation in a neonatal foal.
Journal of the American Veterinary Medical Association    April 1, 1988   Volume 192, Issue 7 920-922 
Bain FT, Brock KA, Koterba AM.High-frequency jet ventilation was performed on a premature foal for respiratory difficulty attributable to in utero-acquired pneumonia. The procedure involves delivery of compressed gas through a small-bore cannula at frequencies up to 400 cycles/min. Ventilation settings of drive pressure, frequency, and FIO2 were varied to optimize PaO2 and PaCO2 values. The foal was ventilated with this equipment for 14 hours. Evidence of a favorable response to this method of ventilation was observed in the form of improvement in arterial blood gas values as well as the foal's attitude and degree of respi...
British Columbia. Lyme Disease in horses.
The Canadian veterinary journal = La revue veterinaire canadienne    April 1, 1988   Volume 29, Issue 4 393-394 
Burgess B.No abstract available