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Topic:Dysphagia

Dysphagia in horses refers to the difficulty or inability to swallow, which can result from a variety of underlying conditions affecting the oral cavity, pharynx, esophagus, or nervous system. This condition can lead to complications such as aspiration pneumonia, malnutrition, and dehydration. Dysphagia may be caused by dental problems, neurological disorders, or structural abnormalities, among other factors. Diagnosis typically involves a thorough clinical examination, imaging, and endoscopic evaluation. This page compiles peer-reviewed research studies and scholarly articles that explore the causes, diagnostic approaches, and management strategies for dysphagia in equine patients.
When Changing the Hay Makes a Difference: A Series of Case Reports.
Journal of equine veterinary science    March 24, 2022   Volume 113 103940 doi: 10.1016/j.jevs.2022.103940
Cavallini D, Penazzi L, Valle E, Raspa F, Bergero D, Formigoni A, Fusaro I.Dry hay (composed of grass, legumes, or a mixture of the two) provides the primary source of alimentary fiber in stabled horses with limited access to fresh pasture. However, hay can also give rise to health problems in the horse, depending on the quality and quantity of its components. Pathologies may be rooted in biological problems, such as inadequate digestion disturbances, or reflect mechanical difficulties-for example, due to the presence of sharp plant parts that irritate the oral mucosa, or due to physical intake problems that inhibit consumption. Unwanted plants in the hay may cause s...
Management of postoperative dysphagia after prosthetic laryngoplasty or arytenoidectomy.
Veterinary surgery : VS    February 4, 2020   Volume 49, Issue 3 529-539 doi: 10.1111/vsu.13389
Luedke LK, Cheetham J, Mohammed HO, Ducharme NG.To evaluate the efficacy of various treatments for dysphagia after laryngeal surgery. Methods: Retrospective. Methods: Horses treated for dysphagia after laryngeal surgery. Methods: Medical records of horses treated for dysphagia after prosthetic laryngoplasty (PLP) or partial arytenoidectomy (PA) were reviewed. Signalment, prior surgery, preoperative videoendoscopic diagnosis, and surgical treatments were recorded. Short- and long-term follow-up were obtained. Chi-square and logistical regression were performed to correlate independent variables and outcomes. Results: Forty-four percent of ho...
Reversible dysphagia secondary to guttural pouch mycosis in a gelding treated medically with voriconazole and surgically with carotid occlusion and esophagostomy.
The Canadian veterinary journal = La revue veterinaire canadienne    February 2, 2018   Volume 59, Issue 2 165-170 
Whitehead AE, Whitty J, Scott M, Léguillette R.A gelding was diagnosed with dysphagia and left guttural pouch mycosis. Treatments included topical antifungal drugs, systemic voriconazole, and balloon occlusion of the internal carotid artery. Ongoing dysphagia of neurological origin necessitated extra-oral feeding through an esophagostomy tube. Complementary case management included acupuncture. Clinical remission occurred over 10 weeks. Dysphagie réversible secondaire à une mycose de la poche gutturale chez un hongre traité médicalement avec du voriconazole et chirurgicalement par l’occlusion de la carotide et l’œsophagostomie. Un...
[A case of leptomeningeal melanomatosis with acute paraplegia and multiple cranial nerve palsies].
Rinsho shinkeigaku = Clinical neurology    November 28, 2017   Volume 57, Issue 12 769-774 doi: 10.5692/clinicalneurol.cn-001092
Hattori K, Matsuda N, Murakami T, Ito E, Ugawa Y.A 62-year-old man with acute paraplegia was transferred to our hospital. He had flaccid paraplegia and multiple cranial nerve palsies, such as mydriasis of the left pupil, abduction palsy of the left eye, hoarseness and dysphagia, but no meningeal irritation signs. MRI of the spinal canal showed swellings of the conus medullaris and the cauda equine, and also contrast enhancement of the spinal meninges. The cerebrospinal fluid (CSF) showed pleocytosis and protein increment. The lymph node was swollen in his right axilla. The biopsy specimen from the right axillary lymph node revealed metastasi...
Aryepiglottic fold augmentation as treatment for late-onset dysphagia following surgical treatment of recurrent laryngeal neuropathy.
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    July 26, 2017   Volume 45, Issue 4 219-225 doi: 10.15653/TPG-160712
Vidovic A, Delling U.Coughing and dysphagia have been described following prosthetic laryngoplasty (LP) with or without ventriculectomy/ventriculocordectomy (VE/VCE) for the treatment of recurrent laryngeal neuropathy. All previous case descriptions include patients with acute onset of clinical signs after surgery that persisted. The authors observed a late-onset of dysphagia and coughing months to years after LP ± VE/VCE. The condition was always associated with an abnormality of the aryepiglottic fold (AEF). Treatment options for those patients are limited. We suggest augmentation of the AEF as treatment for ...
Sarcocystis fayeri in skeletal muscle of horses with neuromuscular disease.
Neuromuscular disorders : NMD    October 1, 2015   Volume 26, Issue 1 85-93 doi: 10.1016/j.nmd.2015.09.014
Aleman M, Shapiro K, Sisó S, Williams DC, Rejmanek D, Aguilar B, Conrad PA.Recent reports of Sarcocystis fayeri-induced toxicity in people consuming horse meat warrant investigation on the prevalence and molecular characterization of Sarcocystis spp. infection in horses. Sarcocysts in skeletal muscle of horses have been commonly regarded as an incidental finding. In this study, we investigated the prevalence of sarcocysts in skeletal muscle of horses with neuromuscular disease. Our findings indicated that S. fayeri infection was common in young mature horses with neuromuscular disease and could be associated with myopathic and neurogenic processes. The number of in...
Laryngeal advancement surgery improves swallowing function in a reversible equine dysphagia model.
Equine veterinary journal    May 13, 2015   Volume 48, Issue 3 362-367 doi: 10.1111/evj.12430
Virgin JE, Holcombe SJ, Caron JP, Cheetham J, Kurtz KA, Roessner HA, Ducharme NG, Hauptman JG, Nelson NC.Pharyngeal dysphagia is a debilitating, sometimes fatal condition in horses, with multiple aetiologies. The pathophysiology is complex and not fully understood. Treatment is largely supportive. Laryngeal advancement surgery may diminish symptoms of dysphagia and improve swallowing in affected horses. Objective: 1) to induce reversible moderate and marked pharyngeal dysphagia by regional anaesthesia of branches of the glossopharyngeal (IX), vagus (X) and hypoglossal (XII) nerves; 2) to characterise the dysphagia produced by each model; and 3) to determine whether laryngeal advancement surgery i...
Evaluation of a technique for percutaneous endoscopic gastrostomy tube placement in horses.
American journal of veterinary research    March 29, 2014   Volume 75, Issue 4 354-360 doi: 10.2460/ajvr.75.4.354
Toth B, Bertin FR, Miller MA, Charney VA, Kritchevsky JE.To develop and assess the short-term feasibility, maintenance, and complications associated with percutaneous endoscopic gastrostomy (PEG) tube placement in standing horses. Methods: 6 adult horses. Methods: Feasibility of the technique was evaluated in 2 horses. In each of 4 other horses, a PEG tube was maintained for 14 days and used to provide fluid requirements during the latter 7 days, before removal. Following air inflation of the stomach, each PEG tube was placed via a left intercostal approach; proper tube location was ascertained by percutaneous ultrasonography and gastroscopy. The ho...
Adenocarcinoma involving the tongue and the epiglottis in a horse.
The Journal of veterinary medical science    November 27, 2013   Volume 76, Issue 3 467-470 doi: 10.1292/jvms.13-0417
Laus F, Rossi G, Paggi E, Bordicchia M, Fratini M, Tesei B.Tumors involving the oral cavity of the horse are uncommon. No cases of equine adenocarcinoma on the dorsum of the tongue have been reported in the literature. We report a case of adenocarcinoma located on the dorsum of the posterior one-third of the tongue in a 29-year-old gelding with severe dysphagia. Endoscopy revealed an epiglottis involvement, and histology was consistent with adenocarcinoma arising from minor salivary glands, which was associated with a severe fungal colonization of affected tissues. The goals of this report are to present an uncommon case of dorsum of the tongue-associ...
Dysphagia caused by focal guttural pouch mycosis: mononeuropathy of the pharyngeal ramus of the vagal nerve in a 20-year-old pony mare.
Irish veterinary journal    July 11, 2013   Volume 66, Issue 1 13 doi: 10.1186/2046-0481-66-13
Eichentopf A, Snyder A, Recknagel S, Uhlig A, Waltl V, Schusser GF.A 20-year-old pony mare was presented to the equine hospital with a ten-day history of dysphagia, regurgitation and coughing. An obstruction of the oesophagus was excluded via endoscopy, but the proximal oesophagus appeared to be distended and circular contractions were missing. A guttural pouch endoscopy revealed a single, black-mottled plaque on the pharyngeal ramus of the vagus nerve in the left guttural pouch, causing a local swelling of this nerve. The pharyngeal ramus seemed to be atrophic distal to the lesion. A biopsy was taken from the lesion and histopathological findings proved the ...
Guttural pouch mycosis in horses: a retrospective study of 28 cases.
The Veterinary record    October 31, 2012   Volume 171, Issue 22 561 doi: 10.1136/vr.100700
Dobesova O, Schwarz B, Velde K, Jahn P, Zert Z, Bezdekova B.The medical records of 28 horses with guttural pouch mycosis were reviewed. The most commonly observed clinical signs were nasal discharge, epistaxis, dysphagia and/or cough. All 28 horses had the disease unilaterally, however, in five of them, it had spread into the contralateral pouch via the mesial septum. Three horses were treated medically, 11 horses underwent surgery and seven horses were treated both medically and surgically. Fifty percent of horses (14/28) were euthanased or died, fifty percent of horses (14/28) survived. There was no significant correlation between treatment method (m...
Dysphagia associated with presumed pharyngeal dysfunction in 16 neonatal foals.
Equine veterinary journal. Supplement    May 19, 2012   Issue 41 105-108 doi: 10.1111/j.2042-3306.2011.00451.x
Holcombe SJ, Hurcombe SD, Barr BS, Schott HC.Dysphagia due to pharyngeal dysfunction occurs in human neonates and is associated with prematurity and hypoxic episodes. This syndrome probably occurs in neonatal foals but has not been reported. Objective: The objectives of this study were to describe 1) a series of neonatal foals with dysphagia due to pharyngeal dysfunction; 2) the progression, treatment and resolution of the dysphagia; 3) the comorbidities; and 4) the prognosis for life and athleticism for affected foals. Methods: Records from 3 referral equine hospitals were reviewed from neonatal foals with dysphagia of pharyngeal origin...
Effects of intravenously administered esomeprazole sodium on gastric juice pH in adult female horses.
Journal of veterinary internal medicine    April 1, 2011   Volume 25, Issue 3 558-562 doi: 10.1111/j.1939-1676.2011.0716.x
Videla R, Sommardahl CS, Elliott SB, Vasili A, Andrews FM.Gastric ulcers are common in horses and treatment of horses that cannot be administered oral medication can be problematic. Objective: To evaluate the efficacy of esomeprazole sodium administered intravenously on gastric juice pH and gastric ulcer scores in horses. Methods: Twelve adult female Quarter Horses. Methods: Esomeprazole sodium (0.5 mg/kg IV) was administered once daily to 8 horses (treatment group) and saline (5 mL IV) was administered to 4 horses (control group) for 13 consecutive days. Gastroscopy was performed and gastric juice pH and gastric ulcer score were recorded before and ...
Equine grass sickness: epidemiology, diagnosis, and global distribution.
The Veterinary clinics of North America. Equine practice    July 8, 2009   Volume 25, Issue 2 381-399 doi: 10.1016/j.cveq.2009.04.006
Wylie CE, Proudman CJ.Equine grass sickness (EGS) is recognized as a debilitating and predominantly fatal neurodegenerative disease affecting grazing equids. The gastrointestinal tract is the most severely affected body system, resulting in the main clinical signs of colic (acute grass sickness), weight loss, or dysphagia (chronic grass sickness). EGS predominantly occurs within Great Britain, although it is also recognized in regions of mainland Europe, and mainly affects young horses with access to pasture in the springtime. There is strong evidence of an association between EGS and the type C toxins produced by ...
Fibrosis of the masseter leading to trismus and dysphagia in a mare.
The Veterinary record    May 12, 2009   Volume 164, Issue 19 597-598 doi: 10.1136/vr.164.19.597
Aharonson-Raz K, Milgram J, Chai O, Sutton GA.No abstract available
Progression of mycosis of the auditory tube diverticulum (guttural pouch) after arterial occlusion in a horse with contralateral temporohyoid osteoarthropathy.
Journal of the American Veterinary Medical Association    December 19, 2006   Volume 229, Issue 12 1945-1948 doi: 10.2460/javma.229.12.1945
Ernst NS, Freeman DE, Mackay RJ.A 6-year-old Appaloosa mare was examined because of inappetance, difficulty eating, and swelling and mucopurulent discharge in the right eye. Results: Results of a CBC and serum bio-chemical analysis revealed no important findings. Ophthalmologic examination revealed scarring and ulceration of the superficial layers of the cornea. Endoscopic examination of the upper portion of the respiratory tract and auditory tube diverticula (guttural pouches) revealed abnormal thickness of the right stylohyoid bone and a plaque suggestive of mycotic growth on the left internal carotid artery. Radiographic ...
Changes of blood biochemical values in ponies recovering from hyperlipemia in Japan.
The Journal of veterinary medical science    May 9, 2006   Volume 68, Issue 4 353-359 doi: 10.1292/jvms.68.353
Oikawa S, McGuirk S, Nishibe K, Higuchi T, Kurosawa T, Watanuki M, Satoh H.Hyperlipemia in horses is a disorder of lipid metabolism peculiar to ponies. This study reports changes of blood biochemical values from the acute to the postconvalescent phases in 3 Shetland ponies with hyperlipemia in Japan. Diseased ponies (all 7 to 9 years old, in late pregnancy, and obese) were fed in the same farm. The periods of their hospitalizations ranged from 30 to 45 days. Twelve well-conditioned ponies (3 to 13 years old) around parturition were used to establish baseline values for blood test results. Main clinical findings in the affected ponies were depression, dysphagia, anore...
The effect of bilateral glossopharyngeal nerve anaesthesia on swallowing in horses.
Equine veterinary journal    January 18, 2005   Volume 37, Issue 1 65-69 doi: 10.2746/0425164054406900
Klebe EA, Holcombe SJ, Rosenstein D, Boruta D, Bartner LR, Tessier C.Dysfunction of the glossopharyngeal nerve has been implicated as a cause of dysphagia in horses. However, recent studies have indicated that this is not the case. Objective: To determine whether bilateral glossopharyngeal nerve anaesthesia would cause dysphagia in horses or result in measurable alterations in the timing, function, or sequence of swallowing. Methods: Swallowing was evaluated in 6 normal horses with and without bilateral glossopharyngeal nerve anaesthesia. Swallowing dynamics were assessed subjectively and objectively based on time from prehension of food until swallowing, numbe...
Recurrent esophageal obstruction and dysphagia due to a brainstem melanoma in a horse.
Journal of veterinary internal medicine    April 3, 2004   Volume 18, Issue 2 245-247 doi: 10.1892/0891-6640(2004)182.0.co;2
Covington AL, Magdesian KG, Madigan JE, Maleski K, Gray LC, Smith PA, Wisner ER.No abstract available
Botulism in foals less than 6 months of age: 30 cases (1989-2002).
Journal of veterinary internal medicine    October 8, 2003   Volume 17, Issue 5 702-707 doi: 10.1111/j.1939-1676.2003.tb02503.x
Wilkins PA, Palmer JE.Botulism has been recognized as a clinical entity in foals since the 1960s. Also known as "Shaker foal" disease, the toxicoinfectious form of botulism affects foals, with the highest incidence in the United States seen in Kentucky and the mid-Atlantic region. The disease is characterized by progressive muscular weakness caused by the action of botulism neurotoxin at cholinergic neuromuscular junctions. Increased number of episodes and duration of recumbency, muscular trembling, and dysphagia are seen in affected foals. Left untreated, the disease can be rapidly fatal, with death occuring secon...
Long-term survey of laryngoplasty and ventriculocordectomy in an older, mixed-breed population of 200 horses. Part 1: Maintenance of surgical arytenoid abduction and complications of surgery.
Equine veterinary journal    July 26, 2003   Volume 35, Issue 4 389-396 doi: 10.2746/042516403776014172
Dixon RM, McGorum BC, Railton DI, Hawe C, Tremaine WH, Dacre K, McCann J.Laryngoplasty (LP) is currently the most common surgical treatment for equine laryngeal paralysis, however, there have been no reports quantifying the degree of retention of arytenoid abduction following LP. Additionally, the complications of LP have been poorly documented. Objective: To record the degree of arytenoid abduction retention following LP and to accurately document all complications of surgery. Methods: A study (1986-1998) of 200 horses of mixed breed and workload, median age 6 years (prospective 136 cases and retrospective 64 cases) undergoing LP (using 2 stainless steel wires) an...
Disorders of the pharynx.
The Veterinary clinics of North America. Equine practice    May 16, 2003   Volume 19, Issue 1 159-viii doi: 10.1016/s0749-0739(02)00071-8
Sullivan EK, Parente EJ.Pharyngeal disorders are complex and difficult to treat. Disorders that lead to anatomic derangement, such as trauma and neoplasia, can significantly affect the function of this organ. Pharyngeal dysfunction can manifest as dysphagia, persistent palatal displacement, or exercise intolerance. Secondary complications are serious and life threatening and include aspiration pneumonia, weight loss, and death. Pharyngeal disorders that are only recognizable during strenuous exercise are difficult to diagnose and are treated with limited success, even though they are responsible for significant econo...
Extramedullary plasmacytoma in a horse with ptyalism and dysphagia. McConkey S, López A, Pringle J.A Clydesdale mare was examined for weight loss, inappetence, ptyalism, and dysphagia. The main abnormality revealed by serum biochemistry was a marked hyperglobulinemia, and protein electrophoresis revealed a monoclonal gammopathy in the gamma region. The urine was positive for Bence Jones proteins. These findings suggested a plasma cell tumor. The neoplasm could not be located with extensive antemortem examination. At postmortem, neoplastic cells morphologically compatible with plasma cells and positive for equine IgG with imunoperoxidase staining infiltrated the pericardium, mediastinal stro...
The neurology and enterology of equine grass sickness: a review of basic mechanisms.
Neurogastroenterology and motility    May 13, 1999   Volume 11, Issue 2 79-92 doi: 10.1046/j.1365-2982.1999.00140.x
Cottrell DF, McGorum BC, Pearson GT.Autonomic dysfunction constitutes a prominent clinical feature of equine grass sickness (EGS). Significant injury to the nervous control of the alimentary system is life threatening, partly because of dysphagia but also because of the failure of the unique regulatory mechanisms in equine digestion involving water and electrolyte balance. The neuropathology also indicates the presence of a somatic polyneuropathy. The morphological features of EGS are similar to those of excitotoxic neuronal degeneration, which resembles neuronal apoptosis. It is difficult to ascertain from published accounts th...
Hyperkalaemic periodic paralysis in homozygous and heterozygous horses: a co-dominant genetic condition.
Equine veterinary journal    April 23, 1999   Volume 31, Issue 2 153-159 doi: 10.1111/j.2042-3306.1999.tb03809.x
Naylor JM, Nickel DD, Trimino G, Card C, Lightfoot K, Adams G.Historical, clinical and experimental data were collected from 9 horses homozygous for HYPP (H/H). All showed episodes of respiratory stertor, described as a rattling or honking sound, usually within the first week post partum. Five horses had one or more episodes of dysphagia, in 3 horses this was accompanied by drooling and in 3 by weight loss. In comparison, only one of 35 contemporaneous half siblings (of which approximately half would be expected to be of the H/N genotype and half N/N) was observed to have respiratory stertor prior to weaning and none had problems with dysphagia. One matu...
Persistent right aortic arch in a yearling horse.
The Canadian veterinary journal = La revue veterinaire canadienne    November 18, 1998   Volume 39, Issue 11 714-715 
Butt TD, MacDonald DG, Crawford WH, Dechant JE.A 14-month-old filly with chronic pharyngitis was diagnosed with incomplete esophageal constriction and megaesophagus due to a persistent right aortic arch. This report is unusual because clinical signs of respiratory dysfunction secondary to chronic regurgitation occurred prior to the recognition of dysphagia.
Equine botulism.
The Veterinary record    July 12, 1997   Volume 141, Issue 2 56 
Dyson S, Marr CM, Barr TJ.No abstract available
Laryngospasm, dysphagia, and emaciation associated with hyperkalemic periodic paralysis in a horse.
Journal of the American Veterinary Medical Association    July 1, 1996   Volume 209, Issue 1 115-117 
Guglick MA, MacAllister CG, Breazile JE.An 18-month-old Quarter Horse gelding was examined because of weight loss and dysphagia of 1 month's duration. Clinical signs included lethargy, dehydration, ptyalism, and probable aspiration pneumonia. Severe dyspnea and cyanosis were evident after mild exercise. Endoscopy revealed laryngospasm and pharyngospasm. Because clinical signs and endoscopic findings were suggestive of hyperkalemic periodic paralysis (HPP), acetazolamide treatment was instituted. Marked improvement was observed within 48 hours. The horse was determined to be homozygous for HPP. It is likely that this horse's dysphagi...
Electrolyte and acid-base disturbances in the horse.
The Veterinary clinics of North America. Equine practice    December 1, 1995   Volume 11, Issue 3 491-514 doi: 10.1016/s0749-0739(17)30312-7
Johnson PJ.Laboratory electrolyte and acid-base analyses are important for the characterization and assessment of the severity of disorders of fluid balance, and they enable the veterinarian to institute appropriate corrective therapeutic interventions. Abnormalities of electrolytes or acid-base rarely define the diagnosis, but certain diseases are characterized by predictable trends in these parameters. Important clinical situations in which assessment of electrolyte and acid-base status should be regarded as important to the equine practitioner include diarrhea, severe colic, peritonitis, pleuritis, dy...
Use of clinical measurements to predict the outcome in chronic cases of grass sickness (equine dysautonomia).
The Veterinary record    April 23, 1994   Volume 134, Issue 17 438-440 doi: 10.1136/vr.134.17.438
Milne EM, Woodman MP, Doxey DL.Forty-five cases of chronic grass sickness were given scores for selected clinical measurements when they were first examined, to assess their value in predicting survival. Sixteen cases survived. The clinical scores for the degree of dysphagia, appetite, colic and the degree of reduction in gut sounds were significantly lower in the survivors than in the non-survivors. In addition, only the non-survivors had severe rhinitis. Ponies were significantly less likely to survive than cob types.