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Topic:Epidemiology

Epidemiology in horses involves the study of the distribution and determinants of health-related states and events in equine populations. It encompasses the investigation of patterns, causes, and effects of diseases and health conditions within horse populations. This field of study aims to identify risk factors for disease and targets for preventive healthcare. Key components of equine epidemiology include disease surveillance, outbreak investigation, and the study of disease dynamics within herds or regions. Research in this area often focuses on infectious diseases, zoonotic diseases, and the impact of environmental factors on equine health. This page compiles peer-reviewed research studies and scholarly articles that explore various aspects of epidemiology in horses, including disease prevalence, transmission pathways, and strategies for disease prevention and control.
Epitope-blocking enzyme-linked immunosorbent assay to differentiate west nile virus from Japanese encephalitis virus infections in equine sera.
Clinical and vaccine immunology : CVI    June 27, 2007   Volume 14, Issue 8 1024-1031 doi: 10.1128/CVI.00051-07
Kitai Y, Shoda M, Kondo T, Konishi E.West Nile virus (WNV) is now widely distributed worldwide, except in most areas of Asia where Japanese encephalitis virus (JEV) is distributed. Considering the movement and migration of reservoir birds, there is concern that WNV may be introduced in Asian countries. Although manuals and guidelines for serological tests have been created in Japan in preparedness for the introduction of WNV, differential diagnosis between WNV and JEV may be complicated by antigenic cross-reactivities between these flaviviruses. Here, we generated a monoclonal antibody specific for the nonstructural protein 1 (NS...
[Presence of west Nile virus in northeast Mexico].
Salud publica de Mexico    June 26, 2007   Volume 49, Issue 3 210-217 doi: 10.1590/s0036-36342007000300006
Fernández-Salas I, de Lourdes Garza-Rodríguez M, Beaty BJ, Jiménez JR, Rivas-Estilla AM.To investigate the presence of WNV in birds, horses and humans in northeast Mexico. Methods: Serum samples from 33 birds, 24 horses and 237 humans were screened by ELISA for Anti-WNV antibodies. Human serum samples were also screened for WNV RNA using an RT-PCR assay. Results: Positive sera were found in three birds and 15 horses. Forty percent of the human serum samples were positive for IgG antibodies and 0% for IgM antibodies and viral RNA. Conclusions: The results of this study show that WNV is present in northeast Mexico and it is a new emergent infectious agent that represents a challeng...
Equine rhinosporidiosis.
The Veterinary record    June 26, 2007   Volume 160, Issue 25 883 doi: 10.1136/vr.160.25.883-c
Peaty M.No abstract available
Are distributions of secondary osteon variants useful for interpreting load history in mammalian bones?
Cells, tissues, organs    June 26, 2007   Volume 185, Issue 4 285-307 doi: 10.1159/000102176
Skedros JG, Sorenson SM, Jenson NH.In cortical bone, basic multicellular units (BMUs) produce secondary osteons that mediate adaptations, including variations in their population densities and cross-sectional areas. Additional important BMU-related adaptations might include atypical secondary osteon morphologies (zoned, connected, drifting, elongated, multiple canal). These variants often reflect osteonal branching that enhances toughness by increasing interfacial (cement line) complexity. If these characteristics correlate with strain mode/magnitude-related parameters of habitual loading, then BMUs might produce adaptive diffe...
Population sub-structuring among Trypanosoma evansi stocks.
Parasitology research    June 22, 2007   Volume 101, Issue 5 1215-1224 doi: 10.1007/s00436-007-0603-y
Njiru ZK, Constantine CC.To investigate the population genetic structure of Trypanosoma evansi from domesticated animals, we have analysed 112 stocks from camels, buffaloes, cattle and horses using the tandemly repeated coding sequence (MORF2) and minisatellite markers 292 and cysteine-rich acidic integral membrane protein (CRAM). We recorded a total of six alleles at the MORF2 locus, seven at 292 and 12 at the CRAM loci. Nei's genetic distance showed reduced allelic diversity between buffaloes and cattle stocks (1.2) as compared to the diversity between camels and buffaloes (3.75) and camels and cattle stock (1.69). ...
Relationships between uterine culture, cytology and pregnancy rates in a Thoroughbred practice.
Theriogenology    June 21, 2007   Volume 68, Issue 3 395-402 doi: 10.1016/j.theriogenology.2007.05.050
Riddle WT, LeBlanc MM, Stromberg AJ.Endometrial cytology and culture specimens (n=2123) were collected concurrently with a guarded uterine culture instrument from 970 mares (738 barren, 1230 foaling and 155 maiden mares) during three breeding seasons (2001-2004). Results were compared to the 28-d pregnancy rate for the cycle from which the samples were taken. Cytological smears were evaluated for inflammation at x100 and graded as: not inflammatory (0-2 neutrophils/field), moderate inflammation (2-5 neutrophils/field), severe inflammation (>5 neutrophils/field), or hypocellular (scant epithelial cells and no neutrophils). Ute...
Equine influenza in England.
The Veterinary record    June 19, 2007   Volume 160, Issue 24 851 doi: 10.1136/vr.160.24.851
Newton R, Elton D, Bryant N, Rash A, Hammond TA.No abstract available
Pathomorphological study on gastroduodenal ulceration in horses: localisation of lesions.
Acta veterinaria Hungarica    June 9, 2007   Volume 55, Issue 2 241-249 doi: 10.1556/AVet.55.2007.2.10
Bezdekova B, Jahn P, Vyskocil M.Gastroduodenal ulceration is a prevalent disease in foals and adult horses. Decreased performance as well as fatal complications relate to this syndrome. The objective of our study was to determine the prevalence of gastric ulceration in a mixed population of horses by postmortem examination and to evaluate a possible association between equine gastric ulcer syndrome (EGUS) and sex or age of the examined horses, to evaluate the localisation of lesions in the proximal part of the gastrointestinal tract and to determine the occurrence of gastric parasites. Postmortem examinations were performed ...
Possibility of selecting racehorses on jumping ability based on their steeplechase race results in France, the United Kingdom and Ireland.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie    June 7, 2007   Volume 124, Issue 3 124-132 doi: 10.1111/j.1439-0388.2007.00644.x
Bokor A, Blouin C, Langlois B.The aim of this study was to detect Thoroughbred mare families and sire lines, in France, in the United Kingdom and Ireland, whose offspring may be successful in steeplechase races and can be recommended therefore for sport horse breeding. Race results were collected from all steeplechase races in these countries between 1998 and 2003, which contained the results of 17,355 horses from 12,861 dams and 2452 sires. In France, non-Thoroughbred horses were also included in the analysis because they race and mate together with Thoroughbreds. Performance was measured with two criteria: earnings and r...
Is there a benefit from an early booster vaccination in the control of equine influenza?
Veterinary journal (London, England : 1997)    June 7, 2007   Volume 174, Issue 3 592-598 doi: 10.1016/j.tvjl.2007.03.004
Heldens JG, van Loon AA, van de Zande S.Conventional equine influenza vaccination schedules consist of a primary course of two vaccinations given 4-6 weeks apart followed by a third vaccination (booster) given approximately 5 months later. In between the primary course and the third vaccination, horses are generally considered not to be adequately protected against influenza. This study aimed to investigate whether Thoroughbred foals would benefit from a vaccination schedule in which the third vaccination was given earlier than in conventional vaccination schedules. The vaccines used were an inactivated whole virus equine influenza ...
Molecular characterization of the equine herpesvirus 1 strains RacL11 and Kentucky D.
The Journal of veterinary medical science    June 7, 2007   Volume 69, Issue 5 573-576 doi: 10.1292/jvms.69.573
Ghanem YM, Ibrahim el-SM, Yamada S, Matsumura T, Osterrieder N, Yamaguchi T, Fukushi H.The pathogenicities of RacL11 and Kentucky D strains of equine herpesvirus 1 in the hamster infection model are different from those of Ab4p and the Japanese isolates. Virus genome restriction fragment length polymorphism analysis and sequence comparison of an intergenic region, glycoproteins and tegument genes showed higher conservation but with some strain-specific differences. These results indicate that point nucleotide differences in RacL11 and Kentucky D might be responsible for their pathogenicity in rodent models.
Serological evidence for West Nile virus infection in horses in Croatia.
The Veterinary record    June 5, 2007   Volume 160, Issue 22 772-773 doi: 10.1136/vr.160.22.772
Madić J, Savini G, Di Gennaro A, Monaco F, Jukić B, Kovac S, Rudan N, Listes E.No abstract available
Serum antibodies in mares and foals to Actinobacillus equuli whole cells, outer membrane proteins, and Aqx toxin.
Veterinary immunology and immunopathology    June 3, 2007   Volume 118, Issue 3-4 310-316 doi: 10.1016/j.vetimm.2007.05.013
Holyoak GR, Smith CM, Boyette R, Montelongo M, Wray JH, Ayalew S, Duggan VE, Confer AW.Actinobacillus equuli is carried in the alimentary tract of mares and can cause severe septicemia of neonatal foals. A hemolytic subspecies, A. equuli subsp. haemolyticus, and a non-hemolytic subspecies, A. equuli subsp. equuli, have been identified. Hemolytic strains produce the RTX toxin Aqx. The purpose of this study was to demonstrate sequentially in two sets of mare-foal pairs antibodies to A. equuli whole bacterial cells, outer membrane proteins, and recombinant Aqx and to compare the transfer of antibodies to these antigens between mares and their foals. Two mare/foal sets of sera were ...
Statistical approaches to uncertainty: P values and confidence intervals unpacked.
Equine veterinary journal    May 25, 2007   Volume 39, Issue 3 275-276 doi: 10.1111/j.2042-3306.2007.tb00999.x
Doll H, Carney S.No abstract available
Equine herpesvirus-1-specific interferon gamma (IFNgamma) synthesis by peripheral blood mononuclear cells in thoroughbred horses.
Equine veterinary journal    May 25, 2007   Volume 39, Issue 3 202-209 doi: 10.2746/042516407x174216
Luce R, Shepherd M, Paillot R, Blacklawst B, Wood JL, Kydd JH.An assay has been developed that measures EHV-1 specific interferon gamma synthesis (IFNgamma), a cytokine produced following the activation of memory T lymphocytes and therefore a measure of cell mediated immunity. The method requires validation in the field. Objective: To measure the frequency of EHV-1 specific, IFNgamma synthesising peripheral blood mononuclear cells (PBMC) in a population of Thoroughbred horses, and examine its relationship with age, gender, premises and history of vaccination or field infection with EHV-1. Methods: Lymphocytes from 200 Thoroughbred horses were stimulated ...
Seroprevalence of antibotulinum neurotoxin type C antibodies in horses in Israel.
Equine veterinary journal    May 25, 2007   Volume 39, Issue 3 232-235 doi: 10.2746/042516407x158368
Steinman A, Kachtan I, Levi O, Shpigel NY.Clostridium botulinum type C is prevalent in Israel and outbreaks recorded in many species, other than horses. Association between levels of anti-BoNT/C antibodies and equine grass sickness (EGS) have been demonstrated but seroprevalence of anti-BoNT/C antibodies in horses has not been reported nor has EGS been reported in Israel. Objective: To determine the seroprevalence of specific anti-BoNT/C antibodies in horses in Israel and to determine whether age, breed and gender, or geographical region of farms are potential risk factors for exposure to BoNT/C. Objective: Anti-BoNT/C antibodies are ...
Prevalence, distribution and characterisation of ceftiofur resistance in Salmonella enterica isolated from animals in the USA from 1999 to 2003.
International journal of antimicrobial agents    May 24, 2007   Volume 30, Issue 2 134-142 doi: 10.1016/j.ijantimicag.2007.03.013
Frye JG, Fedorka-Cray PJ.Third-generation cephalosporin (3GC) antimicrobials are the drugs of choice for treatment of salmonellosis in children. Salmonella isolated in the USA are assayed by the National Antimicrobial Resistance Monitoring System (NARMS) for resistance to antimicrobials including first-, second- and third-generation cephalosporins. From 1999 to 2003, 34,411 Salmonella were isolated from animals in the USA, of which 10.9% were found to be resistant to ceftiofur, a 3GC used in animals, whilst only 0.3% were resistant to ceftriaxone, a 3GC used in human medicine. Ceftiofur resistance rose from 4.0% in 19...
Career-ending injuries to professional jockeys in British horse racing (1991-2005).
British journal of sports medicine    May 17, 2007   Volume 42, Issue 1 22-24 doi: 10.1136/bjsm.2007.038950
Balendra G, Turner M, McCrory P.It has been previously shown that professional jump and flat racing jockeys suffer a high incidence of injury as a consequence of their profession. This paper specifically examines career-ending injuries to professional jockeys in Great Britain. Objective: To investigate career-ending injuries in professional jockeys. Methods: Analysis of prospectively collected injury database on professional jockeys. Results: The majority of injuries in this study occurred to the head, shoulder or torso. Fractures were the most common type of injury that led to a decision to end a career, followed by neurolo...
Genetic evaluation of performance traits in Brazilian Quarter Horse.
Journal of applied genetics    May 15, 2007   Volume 48, Issue 2 145-151 doi: 10.1007/BF03194672
Corrêa MJ, da Mota MD.The aim of this study was to estimate genetic parameters for racing performance traits in Quarter Horses in Brazil. The data (provided by the Sorocaba Jockey Club) came from 3 Brazilian hippodromes in 1994-2003, with 11 875 observations of race time and 7775 of the speed index (SI), distributed in 2403 and 2169 races, respectively. The variance components were estimated by the MTGSAM program, under animal models including the random additive genetic effect, random permanent environmental effect, and the fixed effects of sex, age and race. Heritabilities for race time and the SI, for the 3 dist...
Injuries in the Victorian thoroughbred racing industry.
British journal of sports medicine    May 14, 2007   Volume 41, Issue 10 639-643 doi: 10.1136/bjsm.2006.032888
Cowley S, Bowman B, Lawrance M.There is increasing concern in Australia about safety in the thoroughbred racing industry, but there has been no reported analysis of injury data. This review analyses injury and workers' compensation data recorded in Victoria. On the basis of the results, it is recommended that the injury and incident data collection systems are improved such that they are not only more complete but also accumulate more detailed information about the location of an incident or injury event, the activity at the time of the incident or injury event, and factors that may have influenced the occurrence.
Real-time quantitative RT-PCR and PCR assays for a novel European field isolate of equine infectious anaemia virus based on sequence determination of the gag gene.
The Veterinary record    May 8, 2007   Volume 160, Issue 18 611-618 doi: 10.1136/vr.160.18.611
Quinlivan M, Cook RF, Cullinane A.In 2006, an outbreak of equine infectious anaemia (EIA) occurred in Ireland. The initial source of the outbreak is believed to have been contaminated plasma imported from Italy. This paper presents the nucleotide sequence of the gag gene of the virus identified in Ireland (EIAV(Ire)), the first for a European strain of EIAV. Comparison of the gag gene with North American and Asian strains of the virus showed that the gag gene is less well conserved than previously believed, and that EIAV strains can have similar phenotypes despite considerable variations in genotype. On the basis of the deduce...
Methicillin-resistant Staphylococcus aureus ST398 in humans and animals, Central Europe.
Emerging infectious diseases    May 8, 2007   Volume 13, Issue 2 255-258 doi: 10.3201/eid1302.060924
Witte W, Strommenger B, Stanek C, Cuny C.Methicillin-resistant Staphylococcus aureus of clonal lineage ST398 that exhibits related spa types and contains SCCmec elements of types IVa or V has been isolated from colonized and infected humans and companion animals (e.g., dog, pig, horse) in Germany and Austria. Of particular concern is the association of these cases with cases of nosocomial ventilator-associated pneumonia.
Combinatorial selection of a RNA thioaptamer that binds to Venezuelan equine encephalitis virus capsid protein.
FEBS letters    May 4, 2007   Volume 581, Issue 13 2497-2502 doi: 10.1016/j.febslet.2007.04.072
Kang J, Lee MS, Watowich SJ, Gorenstein DG.A phosphorothioate RNA aptamer (thioaptamer) targeting the capsid protein of Venezuelan equine encephalitis virus (VEEV) was isolated by in vitro combinatorial selection. The selected thioaptamer had a strong binding affinity (approximately 7nM) and high specificity for the target protein. For the binding to the protein, the overall tertiary structure of the thioaptamer is required. We introduce two theoretical methods to examine the effect of phosphorothioate modification on the enhancement of binding affinity and one experimental method to examine the nature of the multiple bands of thioapta...
Phenotypical assays and partial sequencing of the hsp60 gene for identification of Streptococcus equi.
Current microbiology    May 4, 2007   Volume 54, Issue 5 331-334 doi: 10.1007/s00284-005-0458-3
Sá e Silva M, da Costa MM, de Avila Botton S, Barretta C, Groff AC, de Vargas AC.Strangles is an acute and contagious disease characterized by inflammation of the upper respiratory tract of horses. The etiological agent of strangles is the bacteria S. equi subsp. equi, which belongs to the Lancefield group C. Opportunistic agents from the same group are frequently isolated from horses with strangles and may induce mistaken diagnoses. Among the subspecies of S. equi, the phenotypic features are almost undistinguishable; however, the pathogenic potential is widely differentiated. The aim of this study was to characterize S. equi isolates obtained from clinical samples of str...
Experimental infections with West Nile virus.
Current opinion in infectious diseases    May 2, 2007   Volume 20, Issue 3 293-297 doi: 10.1097/QCO.0b013e32816b5cad
Bowen RA, Nemeth NM.West Nile virus emerged recently in North America as a serious human and animal pathogen. This review summarizes the use of experimental infections with West Nile virus in diverse vertebrate species that have been used to answer fundamental questions about the host response, pathogenesis of West Nile virus infection and virus evolution. Results: West Nile virus has an extremely broad vertebrate host range. Infection of common species of birds has defined those with high vs. low potential to serve as amplifying hosts for the virus. In general, mammals (primates, horses, companion animals) are d...
Internal abdominal abscesses caused by Streptococcus equi subspecies equi in 10 horses in California between 1989 and 2004.
The Veterinary record    May 1, 2007   Volume 160, Issue 17 589-592 doi: 10.1136/vr.160.17.589
Pusterla N, Whitcomb MB, Wilson WD.No abstract available
Isolation and characterization of Campylobacter spp. from domestic animals and poultry in south of Iran.
Pakistan journal of biological sciences : PJBS    May 1, 2007   Volume 10, Issue 9 1519-1524 doi: 10.3923/pjbs.2007.1519.1524
Baserisalehi M, Bahador N, Kapadnis BP.A total of 455 domestic animals (cow, horse and camel) and poultry from south of Iran were surveyed for fecal carriage of Campylobacter spp. Out of all collected fecal samples, the highest isolation rate of Campylobacter was recorded among poultry (35%), followed by horse (27%) and cow (21%) while, lowest isolation rate was recorded among camel. Of the 85 Campylobacter strains isolated, 76 were classified as catalase positive Campylobacter. Out of them, high frequency of occurrence was belonged to Campy. jejuni. Furthermore, catalase positive Campylobacter spp. were isolated from all the sourc...
[Prevalence of hereditary diseases in three-year-old Swiss Warmblood horses].
Schweizer Archiv fur Tierheilkunde    April 28, 2007   Volume 149, Issue 4 161-171 doi: 10.1024/0036-7281.149.4.161
Studer S, Gerber V, Straub R, Brehm W, Gaillard C, Lüth A, Burger D.The objective of this study was to investigate clinical signs indicating hereditary diseases like equine sarcoid, osteochondrosis (OC) and the idiopathic laryngeal hemiplegia (ILH), and to demonstrate relationships between environment, feeding habits and conformation ("exterieur" evaluation) of the horses. For this purpose, we analyzed veterinary examinations of 403 stallions at the approvals since 1994 examined 493 three-year-old Swiss Warmblood horses, which were shown at the Swiss-Field-Tests in 2005. With the help of the owners a questionnaire on health, environment and feeding habits of t...
Descriptive study of an outbreak of equine sarcoid in a population of Cape mountain zebra (Equus zebra zebra) in the Gariep Nature Reserve.
Journal of the South African Veterinary Association    April 27, 2007   Volume 77, Issue 4 184-190 doi: 10.4102/jsava.v77i4.375
Nel PJ, Bertschinger H, Williams J, Thompson PN.An outbreak of equine sarcoid occurred in a population of Cape mountain zebra (Equus zebra zebra) at the Gariep Nature Reserve located in the southern Free State Province of South Africa in 1996. The course of the outbreak during 1996 to 2003 is described. During this period the average population size was 69 animals. Initially (1996) all affected animals were removed from the population. New cases continued to manifest and the incidence varied between 4.6% and 17.6%. Prevalence reached 24.7% in 2002. No sexual predilection was noticed in the 39 recorded cases. Of the affected individuals, 64%...
Investigation of the molecular detection of vaccine-derived equine herpesvirus type 1 in blood and nasal secretions from horses following intramuscular vaccination. Pusterla N, Chaney KP, Maes R, Wise AG, Holland R, Schott HC.The objective of this study was to investigate whether intramuscular vaccination of healthy adult horses with a killed or a modified live equine herpesvirus type 1 (EHV-1) vaccine could induce transient positive PCR results in either blood or secretions collected on a nasopharyngeal swab. Four horses in each group received either a single killed or a modified-live vaccine intramuscularly. Two local commingled and 2 distant nonvaccinated controls were included for each group. All horses were observed daily for evidence of clinical abnormalities throughout the study periods. Blood and nasopharyn...