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Topic:Equine Diseases
Equine diseases encompass a wide range of health conditions that can affect horses, including infectious diseases, metabolic disorders, and genetic conditions. These diseases can impact the overall health, performance, and well-being of horses. Common equine diseases include equine influenza, equine herpesvirus, laminitis, and equine metabolic syndrome. Diagnosis and management of these diseases often require a combination of clinical evaluation, laboratory testing, and appropriate treatment strategies. This page gathers peer-reviewed research studies and scholarly articles that explore the etiology, pathophysiology, diagnosis, and treatment options for various equine diseases, providing valuable insights for veterinarians and researchers in the field.
Lesions of contagious equine metritis in mares. Twenty-three mares were infected with contagious equine metritis organism by intrauterine inoculation, and necropsied after intervals of two to 116 days. Severe diffuse subacute salpingitis was seen in one mare, and mild multifocal subacute salpingitis was common. Severe diffuse endometritis and cervicitis initially were acute and became more severe, subacute and predominantly plasmacytic by 14 days, then declined but persisted as mild diffuse or multifocal inflammation for the rest of the experimental period. Vaginitis arose in parallel but resolved after 70 days. There were no lesions in the...
Experimental and clinical investigations of the use of carbon fiber sutures in equine tendon repair. Braided carbon fiber sutures were used to repair surgically transected or lacerated digital flexor tendons of 20 mature horses (10 experimental and 10 clinical cases). In addition, 4 experimental horses had tenectomies that were not surgically repaired; these served as controls for the horses with carbon-implanted tendons. Six of the 10 clinically affected horses were returned to their intended use; 2 were euthanatized because of complications and 2 were still recuperating. The experimental horses were euthanatized at 12 days and 1, 2, 4, 8, and 12 months. Tendon scars were structurally and fu...
Hyperventilation in ponies at the onset of and during steady-state exercise. We studied blood gases in ponies to assess the relationship of alveolar ventilation (VA) to pulmonary CO2 delivery during moderate treadmill exercise. In normal ponies for 1.8, 3, or 6 mph, respectively, partial pressure of CO2 in arterial blood (PaCO2) decreased maximally by 3.1, 4.4, and 5.7 Torr at 30-90 s of exercise and remained below rest by 1.4, 2.3, and 4.5 Torr during steady-state (4-8 min) exercise (P less than 0.01). Partial pressure of O2 in arterial blood (PaO2) and arterial pH, (pHa) also reflected hyperventilation. Mixed venus CO2 partial pressure (PVCO2) decreased 2.3 and 2.9 T...
Electromechanical activity of the equine small intestine and its correlation with transit of fluid through Thiry-Vella loops. Motility patterns in the equine small intestine were investigated in eight ponies. Muscular activity was assessed by means of extramural strain gauge transducers, bi-polar electrodes and in three of the animals, fitted with Thiry-Vella loops, the transit of fluid. Circular muscle contractions were preceded by spiking superimposed on the slow wave and fluid transit in the loops correlated with both these events.
Antibody responses of ponies to initial and challenge infections of Strongylus vulgaris. An indirect fluorescent antibody assay (IFA) was developed using Strongylus vulgaris third stage larvae (L3) as antigens. Observations using the IFA indicate that a species-specific antibody response to S. vulgaris L3 develops in S. vulgaris-infected ponies and that some surface L3 antigens are shared by adult worms. Sequential antibody levels against S. vulgaris were measured in strongyle-naive and in immune ponies following initial and challenge infections using the IFA and an indirect hemagglutination assay (IHA). Antibody levels measured by IFA increased faster following initial infections...
Use of schizont and piroplasm antigens of Babesia equi in the indirect fluorescent antibody and complement fixation tests. Eight ponies infected with Babesia equi were investigated for their serological response to B. equi schizont and piroplasm antigen with the indirect fluorescent antibody test (IFAT) and complement fixation test (CFT). Piroplasm antigen was prepared from an infected splenectomized pony, while schizont antigen was produced from cultured lymphoid cells which contained B. equi macroschizonts. The IFAT detected a rise in antibody titres to schizont antigen as well as to piroplasm antigen, but differences were obtained in the duration of antibody detection. Significant antibody titres to piroplasm a...
Extrinsic and intrinsic veins of the equine hoof wall. The extrinsic and intrinsic venous drainage of the equine hoof have previously been poorly described. There is also an absence of information about the venous organisation of both primary and secondary dermal lamellae of the hoof wall. The purpose of this study was to describe the normal venous pattern of the horse hoof, especially that associated with the dermal lamellae of the wall. The venous organisation of 46 pairs of hooves from clinically healthy horses was studied using standard plastic vascular corrosion casts and histological sections. A consistent pattern of venous organisation was ...
Caecal rupture in parturient mares. The pathology of 4 cases of caecal rupture in foaling mares is described. One of these animals died suddenly, probably when rupture occurred, and 3 survived for 5 to 8 h and died from acute peritonitis.
The pathogenesis of this type of injury is discussed and it is suggested that rupture may arise from the pressure of a foetal hind foot against the caecum when distended by local tympany.
Mobility of the early equine conceptus. Movement of the conceptus within the uterine lumen of barren mares was studied by daily ultrasound examinations on days 11-20 and by rectal palpation on days 15-48 (Experiment 1) and by ultrasound examinations 3 or 4 times per day at 2-4 hour intervals on days 11-16 (Experiment 2). In addition, broodfarm records were analyzed to compare side of ovulation with side of embryo attachment (Experiment 3). The vesicle was found in opposite uterine horns for 43% of the successive, daily, ultrasound examinations on days 11 and 12, 12 and 13, 13 and 14, and 14 and 15; 24% of the successive examinations...
Treadmill for equine locomotion analysis. A treadmill for equine locomotion analysis is described and its potential considered for locomotive research and clinical investigation. The treadmill comprised an endless belt driven by a hydraulic motor at various speeds up to 14 m/sec and the direction of belt movement was reversible. The carrying side of the belt ran over a steel-concrete table which acted as a flat support. The belt itself consisted of a steel base on to which was glued a rubber belt and the surface was covered with a layer of coir matting which permitted some forward sliding of the landing hooves simulating the condition...
A study on the possible role of chymotrypsin in the aetiology of equine chronic obstructive pulmonary disease (COPD). The chymotrypsin activity of seven batches of Micropolyspora faeni and of five batches of Aspergillus fumigatus culture extracts, prepared for inhalation challenge in horses, was assayed and was found to range between 0.29 and 1.45 units/mg protein and 0.02 and 0.20 units/mg protein respectively. Horses affected with chronic obstructive pulmonary disease (COPD) were challenged with two batches of each antigen which had different chymotrypsin activities and no significant correlations were found between the degree of response to challenge and the chymotrypsin activity of the antigens. Inhalatio...
Fixation and orientation of the early equine conceptus. Fixation and orientation of the conceptus within the uterine lumen of 40 barren mares were examined by ultrasound daily on days 11-21 and at three-day intervals thereafter until day 48. The growth curve of the in situ conceptus had a distinct plateau between days 17-24, as determined by measurements of the width and area of conceptuses on the ultrasound images. The vesicle expanded at an average daily rate of 3-4 mm before the plateau and 2-3 mm after the plateau. Dramatic changes occurred in the shape of conceptus. The predominant shapes were approximately as follows: days 11-16, spherical; d...
A review of research on equine locomotion and biomechanics. A review of the literature about equine locomotion and biomechanics is presented to summarise available knowledge and provide perspective to current and proposed research programmes. It is evident that much past research has failed to provide sufficient information on basic principles of these two disciplines and that information is now required before progress can be made on more applied research topics. However, useful contributions have been made in gait typology, analysis of racetrack surface and design and limb kinetics, kinematics and coordination.
Cell-mediated immune response to Babesia equi-transformed lymphoblastoid cells in vitro. The capacity of equine peripheral blood lymphocytes (PBL) to proliferate in the presence of Babesia equi-transformed lymphoblastoid stimulator cells was tested in an autologous as well as in an allogenic one way mixed lymphocyte reaction (MLR). It was found that both autologous and allogeneic responder lymphocytes incorporated high amounts of 3H-thymidine. The incorporation of 3H-thymidine was lower in MLR using as stimulator cells lymphocytes from which the cell line had previously been established, than when using parasitized culture cells as stimulator. Proliferation of PBL was achieved onl...
