Equine diseases encompass a wide range of health conditions that can affect horses, including infectious diseases, metabolic disorders, and genetic conditions. These diseases can impact the overall health, performance, and well-being of horses. Common equine diseases include equine influenza, equine herpesvirus, laminitis, and equine metabolic syndrome. Diagnosis and management of these diseases often require a combination of clinical evaluation, laboratory testing, and appropriate treatment strategies. This page gathers peer-reviewed research studies and scholarly articles that explore the etiology, pathophysiology, diagnosis, and treatment options for various equine diseases, providing valuable insights for veterinarians and researchers in the field.
Stanek KA, Nagle FJ, Bisgard GE, Byrnes WC.Published reports of oxygen consumption (VO2) during exercise in hyperoxia are equivocal. By and large, when measured at the lung using respiratory gas equations, VO2 is elevated in hyperoxia and, when measured at the blood-tissue level using the cardiovascular Fick (CVF) equation, it is unchanged. We sought to provide some insight into this problem by making through the use of both equations simultaneous determinations of VO2 during hyperoxia in exercising ponies. In normoxia, during treadmill exercise (115 m/min, 10% grade) of seven ponies, there was no difference in exercise VO2, whether it...
Lang G.Equine kidney cells disaggregated by treatment with 0.01% collagenase were used in the preparation of primary monolayer cell cultures. The primary cells could be stored for long periods in liquid nitrogen and subsequently subcultivated. These techniques provided a long-term supply of equine kidney cells, free of apparent contamination, from the kidneys of a single fetus.
Shupe JL, Leone NC, Olson AE, Gardner EJ.Investigation of hereditary multiple exostoses in horses under controlled research conditions for 10 years and epidemiologic studies that have spanned up to five generations of human families contain notable similarities. The present study demonstrated that a single dominant autosomal gene is responsible for hereditary multiple exostoses in horses and man. Affected individuals transmit this trait to approximately 50% of their progeny, whereas nonaffected individuals do not transmit the condition to their offspring. The tumors in affected horses are most often present at birth. They tend to be ...
Fujimiya Y, Perryman LE, Crawford TB.Antibody-dependent cellular cytotoxicity and direct cytotoxicity assays were performed with equine infectious anemia virus-infected target cells, equine leukocytes, and equine anti-equine infectious anemia virus antibody to determine whether these mechanisms play a role in controlling viral replication in equine infectious anemia. Direct cytotoxicity was observed by using peripheral blood mononuclear cells from 7 of 10 infected horses. Antibody-dependent cellular cytotoxicity was not observed. The antibody-dependent cellular cytotoxicity reaction in horses was then studied by using sheep eryth...
Valdez H, Taylor TS, McLaughlin SA, Martin MT.Removal of abdominal testes was accomplished in 32 horses ranging in age from 6 to 72 months. Twenty were unilateral and 12 were bilateral abdominal cryptorchids. An incision was made over the superficial inguinal ring, and the extension of the gubernaculum testis was identified and grasped with forceps. Traction was applied to this structure until the vaginal process was everted beyond the superficial inguinal ring. The vaginal process was incised and the protruding structure, usually the epididymis, was grasped. The testis was drawn out by gentle traction on the epididymis, and castration wa...
Liberatori J, Morisio Guidetti L, Conti A.By double diffusion in agarose gel, in well defined experimental conditions, cross reactions were observed between porcine beta-lactoglobulins and anti-bovine beta-lactoglobulin antisera. The immunological reactivity between these beta-lactoglobulins from a monogastric and the ruminant anti beta-lactoglobulin antiserum thus implies a certain degree of similarity between the monomeric beta-lactoglobulins examined and the dimeric of the ruminants. With the same antisera it also proved possible to demonstrate the presence of beta-lactoglobulins in the mammary secretions of another monogastric, na...
Moore JN, Garner HE, Berg JN, Sprouse RF.Cecal fluid from two adult horses was assayed by the limulus amebocyte lysate system for endotoxin before and after carbohydrate overload of the gastrointestinal tract. There were increases in cecal fluid endotoxin concentrations at the 3-, 6-, and 12-hour samplings when compared with base-line values. Concomitant cecal fluid lactate concentrations and pH values increased and decreased, respectively. Both horses subsequently developed clinical signs of acute laminitis.
Willett K, Blackmore DJ.A method is described for the measurement of haptoglobin in equine serum using the peroxidase activity of the haemoglobin-haptoglobin complex. The problems of interference with Fe2+ and Fe3+ ions are described. Normal values for haptoglobin in 629 blood samples from thoroughbreds in training are presented showing a log normal distribution with a 5 per cent to 95 per cent range of 0.42 to 1.7 g/litre. There was no consistent alteration in haptoglobin concentration throughout the season in spite of a change in red cell size and total bilirubin concentration. It is concluded that the measurement ...
Leid RW.The investigation of the mast cell-basophil products has progressed from studies directed solely at implicating histamine or serotonin in allergic diseases to molecular definitions of pathways to target cell activation and mediator release. In addition, within the last several years the detection and molecular characterization of the many other mediators of immediate hypersensitivity have begun. This area should continue to prove a fruitful arena in the future. Identification of the physiologic importance of these mediators in the heaves syndrome or other potential equine allergic syndromes ma...
Byars TD, Halley J.Ultrasound examination allows the diagnostician to examine peripheral soft tissues and many internal organs in a noninvasive manner. In most instances, ultrasound can be utilized to complement other diagnostic aids, but its increased use has revealed the unique advantages of this technique over more established diagnostic tools. The ease with which ultrasound interpretation can be learned and the increased availability of instruments make this approach to diagnosis a valuable asset in the diagnosis of many equine medical diseases.
Fennell C.Skin scrapings from clinical cases of equine skin disorder were examined by culture to determine the micro-organisms involved. In-vitro and in-vivo studies were then made to determine the efficacy of Trichloro-carbanilide as a topical treatment for these cases. The laboratory findings and results of treatment are described, and the value of Trichlorocarbanilide in cases of bacterial, actinomycete and fungal infection assessed.
Mayhew IG, Brewer BD, Reinhard MK, Greiner EC.A fifth stage Strongylus vulgaris migrated through the spinal cord of a 2-year-old, male donkey resulting in progressive paraparesis and then tetraplegia. A profound neutrophilic pleocytosis was detected on analysis of cerebrospinal fluid. The parasite appeared to have entered the mid-lumbar spinal cord, migrated to the cranial thoracic segments, exited, then re-entered the spinal cord a few segments craniad. It then traveled further cranially and was found in the third cervical spinal cord segment. Some parts of the lesion were remarkably free from tissue necrosis, hemorrhage and inflammation...
Yamout SZ, Magdesian KG, Tokarz DA, le Jeune SS.This is a report of a 12-year-old Swedish Warmblood gelding with a ruptured esophageal pulsion diverticulum associated with atypical clinical signs of colic and septic peritonitis on presentation. The location of this diverticulum at the hiatus was unique and was most likely responsible for the unusual presentation of this horse. Diverticule de Zenker intrathoracique chez un cheval. Ceci est un rapport d’un hongre de race Swedish Warmblood âgé de 12 ans présentant un diverticule de Zenker perforé associé à des signes cliniques atypiques de coliques et de péritonite septique à la pré...