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Topic:Equine Diseases
Equine diseases encompass a wide range of health conditions that can affect horses, including infectious diseases, metabolic disorders, and genetic conditions. These diseases can impact the overall health, performance, and well-being of horses. Common equine diseases include equine influenza, equine herpesvirus, laminitis, and equine metabolic syndrome. Diagnosis and management of these diseases often require a combination of clinical evaluation, laboratory testing, and appropriate treatment strategies. This page gathers peer-reviewed research studies and scholarly articles that explore the etiology, pathophysiology, diagnosis, and treatment options for various equine diseases, providing valuable insights for veterinarians and researchers in the field.
A field study of persistence of antibodies in California horses vaccinated against western, eastern, and Venezuelan equine encephalomyelitis. As a result of the continuing threat of Venezuelan equine encephalomyelitis (VEE), a study was made to determine if revaccination against VEE (TC-83 vaccine) was feasible and if revaccination could be incorporated into other routine vaccination practices. Of the horses given annual vaccination with bivalent western equine encephalomyelitis (WEE) and eastern equine encephalomyelitis (EEE) vaccine, 57% retained detectable serum-neutralizing (SN) antiboyd titers for VEE 18 months after the initial VEE vaccination was given. Of horses with no record of WEE-EEE vacinnation, 100% retained detectable...
Efficacy studies with three formulations of cambendazole in horses. Treatment with 3 formulations of cambendazole (paste, pellets, and suspension) was compared with thiabendazole treatment in 181 Quarter Horses (females and intact and altered males) of different ages in 2 experiments. The mean output of strongyle eggs, as measured by eggs per gram of feces (epg), was reduced by at least 95% by the 3 formulations of cambendazole compared with pretreatment epg and epg in simultaneously nonmedicated horses. Eggs of Parascaris equorum were seen in 19 of the younger horses in experiment I. Parascaris eggs were not seen in postmedication fecal samples from 14 horses...
Comparative electrophysiology and pharmacology of mammalian (including one marsupial) intercostal muscle biopsy preparations. Characteristics of minature end-plate potentials (MEPP) of isolated external intercostal muscle preparations of 7 mammalian species (dog, cat, pig, horse, cow, and goat) including 1 marsupial (opossum, Didelphis marsupialis) were determined with intracellular microelectrodes. Mean amplitude (+/- standard error of MEPP for all species was 0.60 +/- 0.06 mV, and the range was 0.28 mV (opossum) to 1.07 mV (pig). Amplitude was inversely correlated (P less than 0.01) with muscle fiber diameter which ranged from 93 mum (opossum) to 51 mum (pig). Mean values for rise time, half-decay time, and frequen...
The equine practice laboratory. The authors discuss the value of a practice laboratory to the equine clinician and its priorities. Laboratory examinations of particular value are described in relation to their clinical application. The need to establish normal values according to laboratory and horse population is stressed. Tables of normal parameters related to age groups of horses in the authors' practice are presented.
Empyema of the equine paranasal sinuses. A survey of 28 cases of chronic purulent infection of the sinuses in the horse showed a relationship between incidence and age, and a probable relationship with breed. Dental disease was apparently the cause of half the cases. The conventional treatment of trephination followed by irrigation with antiseptic solutions resulted in freedom from recurrence of the disease for over 1 year in 17 of the 28 horses. Antibiotic therapy appears to be useless in chronic empyema. The prognosis is adversely affected by the development of facial swelling, a sign seen usually only in long-standing cases.
Gonadal dysgenesis in the mare. Five phenotypically normal but infertile mares were studied; four had karyotypes of 63XO, and one was a 25,64XX/13,63XO mosaic. The mares exhibited small uteri and has small ovaries that lacked germ cells and consisted primarily of undifferentiated ovarian stroma. These cases demonstrate that chromosome analysis is an important technique for the diagnosis of some forms of equine infertility.
Abnormalities of mating behaviour in domestic stallions. Experimental and clinical observations were made to treat abnormal sexual behaviour. The most common cause of abnormality was mismanagement of the animal; over-use and rough treatment at service and too-frequent ejaculation during winter had a detrimental effect on the behaviour of young stallions. Pain due to injury incurred at copulation or when associated with mounting attempts was also a common cause of impotence. Most impotent stallions responded well to re-training and recovery can be achieved without pharmacological treatment in most cases.
Germ cell development and the meiotic prophase in the fetal horse ovary. A histological study of the developing germinal epithelium in the fetal horse ovary shows an enormous wastage of oocytes during the meiotic phase, between Days 73 and 150 of pregnancy. The first groups of oocytes to enter this phage undergo mass degeneration and eventually disappear; few, if any, oocytes develop to primordial follicles. Peripheral oogonia, dividing by mitosis, give rise to more oocytes which pass through the same changes and are also reduced by degeneration, but by Day 150 primordial follicles are fairly common.
Recent observations concerning Klebsiella infections in stallions. A high incidence of Klebsiella contamination in German 'Warmblut' and Thoroughbred stallions is reported. The organism was recovered from the nostrils, prepuce, pre-ejacultory secretion and, in some cases, on the body surface, in the faeces and on the ground of the covering (mating) yard. Fertility was not affected. However, differences of virulence were observed and Type 5 proved to be the most pathogenic.
Early pregnancy testing and its relationship to abortion. A total of 487 Standardbred and Thoroughbred mares at two studs were manually tested for pregnancy at 20 to 24, 30 to 34, and greater than 42 days after service and the abortion rate compared to that obtained in previous years when only the greater than 42-day test was performed. The results indicated that early manual pregnancy testing does not increase the abortion rate if undertaken carefully and enables non-pregnant mares to be re-mated earlier in the same season.
The transfer of passive immunity to the foal and its relation to immune status after birth. The mechanism of transfer of maternal immunity to the foal is reviewed. Maximal efficiency of macromolecular absorption by specialized cells of the small intestine exists soon after birth. The absorptive cells are progressively replaced by more mature-looking cells incapable of taking up large molecules and the rate of absorption is reduced in a linear decline and ceases completely within 24 hr. Passive antibody levels fall rapidly in the first 4 weeks of life to less than half their original values and have usually completely disappeared by 6 months of age. The foal shows immunological compet...
Pelviscopy in the mare. A method of endoscopic examination of the internal genital (pelvic) organs of the mare is described. Special emphasis is placed on the induction of artificial pneumoperitoneum and the installation of an endoscopic peritoneal fistula device for prolonged observation. The potential of pelviscopy in the mare as a diagnostic aid, a new device for research in equine reproduction and as an auxillary aid to teaching is discussed.
Endometrial biopsy as a guide to diagnosis of endometrial pathology in the mare. A safe and simple technique of endometrial biopsy is described which the results suggest is a useful adjunct to the diagnosis of suspected pathological conditions of the uterus. In conjunction with other clinical data and a knowledge of the breeding history, histopathological findings form a basis for prognosis and treatment of the subfertile mare. A system of classification is presented as a basis for continuing work on the correlation of endometrial histopathology with fertility and breeding potential.
Carbonic anhydrase isozymes in American ponies and riding horses: a new polymorphic high-activity type isozyme. A study of the erythrocyte carbonic anhydrases of 219 American ponies and 76 riding horses has revealed the presence of five variants of the low-activity CA B isozyme and two variants of the high-activity CA C isozyme. The previously undetected variant of CA C was found only in the pony population and had an allele frequency of 8.9%. A family study of animals possessing the CA B variant A2 showed an unexpected high frequency of inheritance.
The frequency of infertility in thoroughbred mares. In a group of 852 Thoroughbred mares, 69-7% had foals which survived beyond 6 weeks, 7-1% had dead, premature or full-term foals and 1-1% had foals which died within 6 weeks after birth. Possible factors which may have influenced these data are mentioned.
The gnotobiotic foal in the study of infectious diseases. A method of rearing germ-free gnotobiotic foals is described. To date, four foals have been infected with rhinopneumonitis and the only clinical signs of infection have been a transient fever and leukopaenia; no detailed results are, as yet, available.
Results of insemination of mares with fresh and frozen stallion semen. Artificial insemination using deep-frozen semen was performed on 116 mares in 1973 using twelve ejaculates from eight stallions of the Hanoverian breed. Despite the fact that the quality of the semen used was poor, the majority of the mares inseminated were subfertile and some mares were inseminated during one oestrus only, 44% nevertheless conceived and gave birth to live foals. Of a small group of ten mares inseminated in the same year with fresh semen, seven conceived.
