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Topic:Equine Health
Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Effect of age on sensory nerve conduction velocity in the horse. This study aimed to establish a clinically reproducible method of evaluation of sensory nerve conduction in the horse and to provide reference values in a group of normal horses. Age-related changes in the sensory nerve conduction velocity were of particular interest. Sensory nerve conduction was performed in the lateral palmar nerve. The results revealed an increase in velocity over the first year of life and a subsequent decrease in velocity in older horses. The effect of age must be considered if results from horses in which peripheral nerve disease is suspected are to be interpreted correc...
Arterial blood supply to the ileocaecal junction in the horse. The arteries supplying the ileocaecal junctions of 7 horses were injected with latex via the A. ileocolica and dissected macroscopically. The same basic pattern emerged whereby a single papillary artery arising from the R. ilei mesenterialis, supplied all aspects of the ileocaecal papilla. In one instance, the papillary artery arose directly from the ileocolic artery. No collateral arterial supply to the ileocaecal junction was present in any of the specimens dissected.
Superoxide production by stimulated equine polymorphonuclear leukocytes–inhibition by anti-inflammatory drugs. Polymorphonuclear leukocytes (PMNLs) were isolated from an inflammatory exudate induced in the intercarpal joints of horses by an administration of carrageenin. Their superoxide production at rest and following stimulation with either serum-treated zymosan (STZ) or phorbol myristate acetate (PMA) was measured by cytochrome-c reduction. Stimulation of the cells increased the cytochrome-c reduction 10-15 times that of resting cells. The maxima were 20 nmol of reduced cytochrome-c per 10(6) cells per ml at 120 min (STZ) and 35 nmol of reduced cytochrome-c per 10(6) cells per ml at 60 min (PMA). T...
Quantitative and qualitative morphology of equine peripheral nerve: teased fibre studies. Single teased fibre studies were made on samples of the lateral palmar nerve from 16 horses of mixed age and size which had no evidence of neuromuscular disease. Significant proportions of abnormal fibres indicative of axonal degeneration/regeneration and demyelination/remyelination were identified. Measurements of internodal length and fibre diameter were made. Internodal length was shown to be related to fibre diameter, changes in this relationship being mainly influenced by the incidence of abnormal fibres rather than by the age of the horse. Information about the incidence of abnormal fibr...
Arthroscopic approaches and intraarticular anatomy of the equine elbow. Periarticular anatomy and techniques for arthroscopic access to the equine elbow were studied in six joints from cadavers. Caudomedial and craniolateral approaches were evaluated subsequently in 11 anesthetized horses. The caudomedial approach was made between the flexor carpi radialis and flexor carpi ulnaris muscle bellies. Most of the caudal articular surfaces of the humeral condyles, the caudal perimeter of the radius, and the trochlear notch and portions of the anconeal process of the ulna could be identified. The voluminous caudal joint capsule cul-de-sac proximal to the anconeal process...
[The aberrant parasitism of horse botflies (Diptera: Gasterophilidae)]. Alongside with a high intensity of infection of horses with botfly larvae there was observed mass aberrant parasitism of horse botflies in farms of Astrakhan, Guryev and Uralsk Provinces, and in the Kalmyk ASSR in 1980-1981 and 1987. As a result of extremely high aggregation of horse botfly larvae in their usual localization places, Gasterophilus pecorum larvae remained, due to interspecific competition, in nonspecific places (oral cavity, pharynx), adapted to new habitats and normally developed. Their number varied from 260 to 750 specimens. Localization of G. pecorum larvae in the mentioned ...
Copper salicylate and copper phenylbutazone as topically applied anti-inflammatory agents in the rat and horse. Topically applied copper phenylbutazone, phenylbutazone, copper salicylate, salicylate and dimethylsulfoxide glycerol (80:20) were investigated as anti-inflammatory agents in rats and horses. Dimethylsulfoxide and glycerol (80:20) or dimethylsulfoxide, ethanol and glycerol (60:20:20) were used as the drug solvents. Subcutaneously administered carrageenin was used to induce inflammatory oedema, either in the paws of rats or the alar fold of the horse. The severity of the oedema and the anti-inflammatory effect of the drugs were assessed by measuring changes in the paw or alar-fold diameters. Co...
Liquid flow and capacity of the caecum and colon of the horse. The rate of flow of fluid from the caecum and from the large colon was measured in four Shetland-type ponies fed a hay diet. In two ponies with cannulas in the caecum and at the origin of the right ventral colon, a continuous intracaecal infusion of a solution of chromium EDTA was used and samples were obtained from the cannula at the origin of the right ventral colon. Based on four determinations, the liquid flow from the caecum was 54.2 +/- 1.89 litres d-1. In the other two ponies with cannulas in the origin of the right ventral colon and near the end of the right dorsal colon, a continuous ...
Mechanical properties of four suture patterns for transected equine tendon repair. Thirty-six superficial digital flexor tendons from nine fresh equine cadavers were transected and sutured with size 2 monofilament nylon. Nine tendons were repaired with each of four suture patterns: single-locking loop, double-locking loop, triple-locking loop, or three-loop pulley. The times required for application, tensile strengths, resistance to distraction (gap), and modes of failure were analyzed. The mean times required were: single-locking loop, 3 mins, 15 secs; double-locking loop, 4 mins, 15 secs; triple-locking loop, 10 mins, 50 secs; and three-loop pulley, 4 mins. The double-lock...
Respiratory muscle electromyogram responses to acute hypoxia in awake ponies. We determined the effect of acute hypoxia on the ventilatory (VE) and electromyogram (EMG) responses of inspiratory (diaphragm) and expiratory (transversus abdominis) muscles in awake spontaneously breathing ponies. Eleven carotid body-intact (CBI) and six chronic carotid body-denervated (CBD) ponies were studied during normoxia (fractional inspired O2 concn [FIO2] = 0.21) and two levels of hypoxia (FIO2 approximately 0.15 and 0.12; 6-10 min/period). Four CBI and five CBD ponies were also hilar nerve (pulmonary vagal) denervated. Mean VE responses to hypoxia were greater in CBI ponies (delta a...
Ultrasound as an aid to diagnosis of granulosa cell tumour in the mare. The ultrasonic appearance of seven cases of granulosa cell tumour is described, and compared with an ovarian haematoma and an ovarian serous cystadenoma. The granulosa cell tumours varied from being uniformly dense to having one or several large fluid filled cysts. Some tumours resembled the haematoma or cystadenoma and also, in some aspects, normal ovarian structures such as corpora haemorrhagica or follicles in early pregnancy. There was no typical ultrasonographic appearance of the granulosa cell tumours which enabled definitive diagnosis. However, ultrasound may be a diagnostic aid when us...
Use of gonadotropin-releasing hormone for hastening ovulation in transitional mares. Natural GnRH and its analog have potential for hastening ovulation in mares. A study was conducted to evaluate the efficacy of a GnRH agonist given either as an injectable or s.c. implant for induction of ovulation in mares. Forty-five seasonally anestrous mares (March) were assigned to one of three groups (n = 15/group): 1) untreated controls; 2) i.m. injection of the GnRH agonist buserelin at 12-h intervals (40 micrograms/injection for 28 d or until ovulation) and 3) GnRH agonist administered as a s.c. implant (approximately 100 micrograms/24 h for 28 d). Six mares per group were bled on d 0...
Induction of immune response and protection from equine viral arteritis (EVA) by formalin inactivated-virus vaccine for EVA in horses. Thirty-nine horses included 3 pregnant mares were examined by inoculating with formalin inactivated-virus vaccine for EVA. Antibody response of horses after one dose vaccination was somewhat poor and 50% effective inoculum dose of the vaccine should be included 10(8.4) pfu of virus before inactivation. After 2 doses given at an interval of 4 weeks, the horses developed such high titer of SN antibody as up to 1:5,120. The SN titer declined rather rapidly, but supplemental administration of the vaccine at an interval of more than 2 months elicited a prompt antibody response and SN titers persist...
A comparison between chromium-mordanted hay and acid-insoluble ash to determine apparent digestibility of a chaffed, molassed hay/straw mixture. The apparent digestibility of a molassed, chaffed grass hay/straw mixture was determined using four mature horses (mean weight 606 kg). Animals were stalled individually and kept on rubber mats. A preliminary feeding period of 18 days was followed by a 10 day collection period. Chromium-mordanted hay was given before the first feed at 08.00 h and subsequent meals were at 12.00, 16.00 and 20.00 h. On Days 3 and 10 of the collection, all faeces were sampled over a 24 h period. In addition, throughout the 10 day collection, faecal material was sampled at 10.00 and 16.00 h. The mean (+/- se) chrom...
Upper airway function during maximal exercise in horses with obstructive upper airway lesions. Effect of surgical treatment. Upper airway pressure was measured during maximal exercise in 10 Thoroughbred racehorses with naturally occurring upper airway obstruction. Left laryngeal hemiplegia and arytenoid chondropathy resulted in substantial increases (30-40 cm H2O) in inspiratory upper airway pressure (Pl), whereas complicated aryepiglottic entrapment and subepiglottic cysts produced only modest increases (15 cm H2O) in Pl. Uncomplicated aryepiglottic entrapment and grade IV pharyngeal lymphoid hyperplasia produced only slight increases (3-5 cm H2O). In general, surgical procedures restored airway pressures to within...
Intracellular proteins of feline immunodeficiency virus and their antigenic relationship with equine infectious anaemia virus proteins. Feline immunodeficiency virus (FIV) grown in cat lymphocyte and thymocyte cultures was labelled with L-[35S]methionine or [3H]glucosamine and virus-coded proteins were identified using immunoprecipitation. Polypeptides with apparent Mr values of 15K, 24K, 43K, 50K, 120K and 160K were detected. An additional polypeptide of 10K was detected by Western blot analysis. The two highest Mr species sometimes appeared as one band, of which only the 120K polypeptide was glycosylated. In the presence of tunicamycin gp120 was no longer detectable and a non-glycosylated precursor of 75K was found instead. ...
Synchronization of locomotion and respiration in trotting ponies. The aim of the present experiment was to investigate the hypothesis that there is a respiration-locomotion coupling in trotting equines. Therefore the respiratory airflow (V), the gastric pressure (Pga) and pleural pressure (Ppl) changes and the step frequency (SF) were simultaneously recorded in 5 trotting ponies (body weight: 255 +/- 15 kg; age: 3.5 +/- 0.4 years). Airflow was measured using a Fleisch pneumotachograph fixed on a face mask. Esophageal and gastric balloon catheters coupled to pressure transducers allowed the recording of Ppl and Pga. The exercise was performed on a treadmill a...
Epidemiology of equine protozoal myeloencephalitis in North America based on histologically confirmed cases. A report. Following a workshop on equine protozoal myeloencephalitis (EPM) convened at the Veterinary Medical Forum of the American College of Veterinary Internal Medicine in 1988, this survey of EPM in North America was developed. It is based upon 364 histologically confirmed case records from California, Florida, Illinois, Kentucky, New York, Ohio, Oklahoma, Ontario, Pennsylvania, and Texas up to 1988. The highest rate of infection was found in young Thoroughbred, Standardbred, and quarter horses. Differences in geographic location, sex, and month (season) of infection were not discernible. This repor...
Effects of left recurrent laryngeal neurectomy, prosthetic laryngoplasty, and subtotal arytenoidectomy on upper airway pressure during maximal exertion. Upper airway pressure was measured with a nasotracheal catheter system and a portable pressure transducer in 10 normal horses during maximal exercise before and after left recurrent laryngeal neurectomy. Measurements were repeated 16 weeks after prosthetic laryngoplasty (5 horses) or subtotal arytenoidectomy (5 horses). During maximal exertion, prosthetic laryngoplasty was more effective than subtotal arytenoidectomy in reversing the increases in upper airway pressure that followed left recurrent laryngeal neurectomy.
Scanning electron and light microscopy of the mucosa of the equine ileocaecal junction. The ileocaecal junction mucosal surface morphology of 5 horses and 1 donkey was examined using scanning electron microscopy and light microscopy. Based on differences in surface morphology, the junction could be divided into 4 distinct regions. The distal extremity of the ileum was characterized by the presence of typical finger-like villi followed by a narrow zone displaying short, stubby villi which gradually merged into a 3rd region representing the true transitional zone between the small and large intestine. In this region the villi fused, forming low ridges arranged in circular, semi-cir...
The transovarial transmission of Babesia caballi by Hyalomma truncatum. Babesia caballi, isolated from a horse that originated from South West Africa/Namibia, was transmitted transovarially by adult Hyalomma truncatum. B. caballi proved to be highly infective for adult H. truncatum. Forty-five per cent of ticks feeding on a reacting animal with an extremely low parasitaemia became infected. In spite of a low parasitaemia, the ticks were severely affected by the parasite. Seventy per cent of the infected ticks either died during oviposition or after laying only a few eggs. The features of the infection in horses were: a prepatent period of 10 days, very low parasit...
Infertility of autoimmune origin in a stallion. THE immunogenicity of mammalian sperm has been recognised since the beginning of this century. In 1909, Adler induced autoantibodies in the serum of guinea pigs by injecting them with their own spermatozoa. Nowadays, the concept of
immunologically privileged sites is well understood and any disruption which allows antigenic contact with the immune system may give rise to an immune response. For example, failure
of the blood/testes barrier following infection, trauma or surgery can lead to the production of antisperm antibodies as a result of spermatozoa coming in contact with the immune syst...
Evaluation of an interfragmentary compression system for the repair of equine femoral capital physeal fractures. Femoral neck and proximal epiphyseal lengths were measured in 37 femurs from 19 cadaver foals that were 1 day to 12 months old to determine the applicability of a human interfragmentary compression system to equine femoral capital physeal fractures. Because components of the implant system are available only in fixed sizes, its use was possible in foals older than 5 weeks of age, but not in younger foals. The 135 degree angle plate conformed best to the equine femur. Femoral capital physeal fractures were created surgically and repaired with the implant system in three foals. Fracture stabilit...
Endotoxin-induced tumor necrosis factor activity production by equine peritoneal macrophages. A study was performed to determine whether equine macrophages produce tumor necrosis factor (TNF) activity in vitro in response to endotoxin and to study the effects of endotoxin concentration and incubation time on the amount of TNF produced. Equine peritoneal macrophages were isolated and cultured in vitro for 2, 6, 12, or 24 hr in tissue culture media containing 1) no additive (nonstimulated control), 2) endotoxin (0.5 ng/ml, 5 ng/ml, or 5 micrograms/ml), or 3) the calcium ionophore A23187 (0.95 microM). The supernatant media concentrations of TNF activity were determined by an in vitro cyt...
Arthrography of the equine shoulder joint. Techniques and normal radiographic anatomy for positive and double contrast shoulder arthrography in horses were evaluated. General anaesthesia was used for most radiographic projections of the shoulder. The mediolateral projection provided the most information during arthrography, although the supinated mediolateral view occasionally allowed better definition of the cartilage surfaces on the medial aspects of the humeral head. The craniocaudal mediolateral oblique and caudocranial projections provided limited additional information. Water soluble non-ionic contrast agents, such as metrizamide...
