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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Quantitation of serum phospholipase A2 by enzyme-diffusion in lecithin agar gels. A comparative study in man and animals.
Acta veterinaria Scandinavica    January 1, 1984   Volume 25, Issue 2 229-241 doi: 10.1186/BF03547267
Westermarck E, Lindberg LA, Sandholm M.A sensitive gel-diffusion assay for determination of phospholipase A was developed. PLA standards, serum, faecal and pancreas homogenate samples with PLA-activity were allowed to diffuse from wells into agar-gels containing lecithin-membranes. The turbidity cleared radially upon PLA-activity. The diameters of the cleared zones showed a linear relationship with the log of the enzyme concentration. Serum samples resulted in some turbidity within the cleared zones. This interference originating from serum lipoproteins could be abolished by hydrophobic absorption. The gel-diffusion method was comp...
Schistocoelia in a twin foal.
Equine veterinary journal    January 1, 1984   Volume 16, Issue 1 69-71 doi: 10.1111/j.2042-3306.1984.tb01858.x
Addo PB, Cook JE, Dennis SM.No abstract available
A giant congenital pigmented nevus in a horse.
The American Journal of dermatopathology    January 1, 1984   Volume 6 Suppl 325-330 
Calderwood Mays MB, Mayhew IG, Woodard JC.Pigmented nevi have not been widely recognized in domesticated animals. We describe, for the first time, a giant congenital pigmented nevus in a horse. Because of a prominent neuroid component within the lesion, neurofibromatosis was the major differential diagnosis.
[Surgical treatment of rectal prolapse in a 1-year-old mare resecting only the mucous membrane].
Tierarztliche Praxis    January 1, 1984   Volume 12, Issue 3 350-353 
Pfeil L, Zetner K.A mare with rectal prolaps was operated at Vienna University. The prolaps was corrected by mucosal resection only. The remaining vital layers of the corresponding intestinal section were saved. The advantage of a special tissue saving operating technique in the rectal area is seen in avoiding postoperative complications.
Studies of erythrocyte glyoxalase II in various domestic species: discovery of glyoxalase II deficiency in the horse.
Animal blood groups and biochemical genetics    January 1, 1984   Volume 15, Issue 1 67-70 doi: 10.1111/j.1365-2052.1984.tb01099.x
Agar NS, Board PG, Bell K.No abstract available
Determination of flunixin in equine plasma by reversed-phase liquid chromatography.
Journal of pharmaceutical and biomedical analysis    January 1, 1984   Volume 2, Issue 3-4 501-508 doi: 10.1016/0731-7085(84)80053-9
Johansson IM, Schubert B.Flunixin is determined in equine plasma by liquid chromatography on LiChrosorb RP-18 with 70% methanol in phosphate buffer pH 3.1 as the eluent, with detection at 284 nm. Plasma is deproteinized with methanol and the supernatant is then injected directly into the system. With a short pre-column (5 x 3 mm i.d.), which is replaced after 25-40 injections of sample, 420 plasma samples could be analysed on one analytical column. The detection limit in plasma is 0.30 micromol/l (89 ng/ml) and the method can be used in pharmacokinetic studies.
Hyaluronic acid concentration in synovial fluid from normal and arthritic joints of horses.
Australian veterinary journal    January 1, 1984   Volume 61, Issue 1 22-24 doi: 10.1111/j.1751-0813.1984.tb07125.x
Hilbert BJ, Rowley G, Antonas KN.A method previously described was used to determine the hyaluronic acid concentration in synovia from normal and arthritic horse joints. The concentration of hyaluronic acid in the synovia from arthritic joints was found to be significantly lower than the concentration in fluid from normal joints.
The mechanism of Na+-L-lactate cotransport by brush-border membrane vesicles from horse kidney. Analysis by isotopic exchange kinetics of a sequential model and stoichiometry.
The Journal of biological chemistry    December 25, 1983   Volume 258, Issue 24 15071-15078 
Mengual R, Leblanc G, Sudaka P.The present study determines the characteristics of isotopic Na and lactate exchange under equilibrium conditions in horse kidney brush-border membrane vesicles. The influence of one solute (Na+ or lactate) on the isotopic exchange of the co-transported species (lactate or Na) was analyzed in detail. Analysis of the data suggests that Na and lactate interact sequentially with the carrier. The observed apparent symmetry between the activating effect of low Na concentrations and the inhibiting effect of high Na concentrations on the lactate exchange process suggests that the carrier functions ac...
Responses to submaximal treadmill exercise and training in the horse: changes in haematology, arterial blood gas and acid base measurements, plasma biochemical values and heart rate.
The Veterinary record    December 24, 1983   Volume 113, Issue 26-27 612-618 
Rose RJ, Allen JR, Hodgson DR, Stewart JH, Chan W.Four standardbred horses with subcutaneously relocated carotid arteries were given a seven week training programme of treadmill exercise at a gradient of 19 per cent in order to assess if there were any effects of exercise and training on haematology, arterial blood gas and acid base measurements, plasma biochemistry and heart rate. The exercise consisted of one minute walking at 110 metres/minute followed by five minutes trotting at 200 metres/minute, twice daily in the first week. The period of trotting exercise was increased by one minute per week so that by the seventh week the horses were...
Miscellaneous: In praise of the Basuto pony.
British medical journal (Clinical research ed.)    December 24, 1983   Volume 287, Issue 6409 1985-1987 doi: 10.1136/bmj.287.6409.1985
Smith SR.No abstract available
Phenylbutazone inhibition of prostaglandin E2 production in equine acute inflammatory exudate.
The Veterinary record    December 24, 1983   Volume 113, Issue 26-27 622-623 
Higgins AJ, Lees P.No abstract available
Chyloabdomen and ultrasonographic detection of an intra-abdominal abscess in a foal.
Journal of the American Veterinary Medical Association    December 15, 1983   Volume 183, Issue 12 1465-1467 
Hanselaer JR, Nyland TG.No abstract available
Toxic hepatic failure in newborn foals.
Journal of the American Veterinary Medical Association    December 15, 1983   Volume 183, Issue 12 1407-1413 
Divers TJ, Warner A, Vaala WE, Whitlock RH, Acland HA, Mansmann RA, Palmer JE.Eight foals, 2 to 5 days of age, with similar clinical signs and laboratory and pathologic findings, died from hepatic failure. The predominant clinical signs were depression and icterus. Abnormally high values were found for plasma ammonia content, aromatic-to-branch-chain amino acid ratio, total serum bilirubin content, gamma glutamyl transferase activity, alkaline phosphatase activity, and PCV; partial thromboplastin time and prothrombin time were prolonged. Some foals had high sorbitol dehydrogenase activity. These laboratory findings were suggestive of subacute hepatic disease and failure...
Race horse helps scholarship fund, has hospital unit named for him.
Review - Federation of American Hospitals    December 12, 1983   Volume 17, Issue 1 110-111 
No abstract available
A distinct environment for iron (III) in the complex with horse spleen apoferritin observed by x-ray absorption spectroscopy.
The Journal of biological chemistry    December 10, 1983   Volume 258, Issue 23 14076-14079 
Sayers DE, Theil EC, Rennick FJ.Cell-specific variations in apoferritin structure correlate with variations in iron metabolism that suggest functional specificity of the protein shell. Using EPR spectroscopy, we previously showed that vanadyl binds to specific sites on apoferritin, and that VO2+ binding is reduced by Fe(II) and Fe(III) (the natural substrates) and by metals known to influence iron storage (Chasteen, N. D., and Theil, E. C. (1982) J. Biol. Chem. 257, 7672-7677). Such observations suggest that the metal-binding site is important to apoferritin function and may define a location where the influence of cell-spec...
[Heart auscultation in the horse (evaluation and description of a new stethoscope)].
DTW. Deutsche tierarztliche Wochenschrift    December 5, 1983   Volume 90, Issue 12 521-523 
Kaemmerer H.No abstract available
[“Organized” hematoma with metaplastic ossification on the flexion side of a horse’s hock].
DTW. Deutsche tierarztliche Wochenschrift    December 5, 1983   Volume 90, Issue 12 524-528 
Stanek C, Grundschober F, Girtler D.No abstract available
Blood lactate as a measure of work intensity in standardbred horses in training.
Australian veterinary journal    December 1, 1983   Volume 60, Issue 12 380-381 doi: 10.1111/j.1751-0813.1983.tb02855.x
Davies R, Pethick DW.No abstract available
Succinylcholine infusion associated with hyperthermia in ponies anesthetized with halothane.
American journal of veterinary research    December 1, 1983   Volume 44, Issue 12 2280-2284 
Hildebrand SV, Howitt GA.Succinylcholine was administered by infusion to halothane-anesthetized ponies to determine dosage requirements for surgical relaxation up to 3 hours' duration. This was not possible to do, since 4 of 6 ponies studied developed severe reactions characterized by prolonged muscle fasciculations after the initial succinylcholine dose, muscle rigidity, hyperthermia, hypercapnia, tachycardia, increasing pulse pressure, and metabolic acidosis. The reactions resembled those associated with malignant hyperthermia, a disease recognized in persons and swine. Two ponies showed signs of the phase II or des...
Isolation and partial characterization of equine alveolar macrophages.
American journal of veterinary research    December 1, 1983   Volume 44, Issue 12 2379-2384 
Dyer RM, Liggitt HD, Leid RW.A device was constructed from an equine nasogastric tube, polyethylene tubing, and a 3-way stopcock and used to lavage the lungs of anesthetized ponies. The technique was safe and atraumatic in that 6.4 to 19.7 X 10(7) purified alveolar macrophages were removed from the lungs without harm to the ponies or contamination of the samples with blood. Studies of these highly purified cell suspensions revealed a mean viability of 85% as assessed by eosin dye exclusion with a mean recovery (+/- SD) of 12.5 +/- 4.8 X 10(7) pulmonary alveolar macrophages/pony.
[Comparative anatomy of the mandible. Functional aspects].
Bulletin de l'Association des anatomistes    December 1, 1983   Volume 67, Issue 199 395-419 
Denoix JM.The structural morphology of the mandibula is presented and correlated to various types of mastication in several Mammalian species. The latter include: Carnivores (Dog, Cat, Cheetah, Lion); Omnivores (Man, Chimpanzee, Hog); Herbivores (Horse, Ox, Goat, Camel, Rabbit). While the mandibula is studied as a composite unit, a more analytical, segmental approach has been included, and both are illustrated by X-rays. The aspects presented underline the distribution as well as the local modifications of compact bone, and in addition, the arrangement and the development of spongy bone trabeculae. A pr...
Increased susceptibility of fibroblasts from horses with severe combined immunodeficiency to growth inhibition by 2′-deoxyadenosine.
Clinical immunology and immunopathology    December 1, 1983   Volume 29, Issue 3 391-402 doi: 10.1016/0090-1229(83)90042-9
Magnuson NS, Decker DM, Perryman LE.The effect of adenosine, deoxyadenosine, guanosine, and deoxyguanosine on the growth rate of fibroblasts derived from normal horses, horses heterozygous for the severe combined immunodeficiency (SCID) trait (heterozygotes), and horses with SCID was studied. All four purines were found to inhibit growth in a dose-dependent manner, but only adenosine and deoxyadenosine were inhibitory at concentrations of less than 100 microM. No statistical difference in sensitivity to adenosine was detected between normal and SCID fibroblasts. Fibroblasts from SCID horses were, however, more sensitive to the g...
Continuous caudal epidural and subarachnoid anesthesia in mares: a comparative study.
American journal of veterinary research    December 1, 1983   Volume 44, Issue 12 2290-2298 
Skarda RT, Muir WW.A new technique for producing continuous caudal epidural analgesia (CEA) and caudal subarachnoid analgesia (CSA) in adult horses (mares) without causing loss of pelvic limb function is described. A modified 17-gauge Huber-point directional needle was used to place a catheter with stylet into either the epidural or subarachnoid space at the lumbosacral intervertebral junction. The catheter was positioned at either the midsacral (S2-3) subarachnoid space or caudal portion of the sacral (S-3 to S-5) epidural space in 7 mares. The position of the catheter was confirmed radiographically. A 2% solut...
Myelopathy and vitamin E deficiency in six Mongolian wild horses.
Journal of the American Veterinary Medical Association    December 1, 1983   Volume 183, Issue 11 1266-1268 
Liu SK, Dolensek EP, Adams CR, Tappe JP.Degenerative myelopathy was diagnosed in six Mongolian wild horses. Three of the horses had a history of ataxia dating from birth to 3 months of age. The clinical signs were uncoordinated movement of the hindlimbs and an abnormally wide-based gait and stance. The other 3 horses had mild ataxia. There were no gross lesions in the brain, vertebrae, or spinal cord. Histologic examination revealed degeneration of the neural processes in the ventral and lateral funiculi of all 6 horses. Myelin sheaths were dilated and vacuolated, and there were swollen, fragmented, or lysed axons. Neuronal degenera...
Differential sensitivity of human, avian, and equine influenza A viruses to a glycoprotein inhibitor of infection: selection of receptor specific variants.
Virology    December 1, 1983   Volume 131, Issue 2 394-408 doi: 10.1016/0042-6822(83)90507-x
Rogers GN, Pritchett TJ, Lane JL, Paulson JC.Human and animal (avian and equine) influenza A virus isolates of the H3 serotype exhibit marked differences in their ability to bind specific sialyloligosaccharide sequences that serve as cell surface receptor determinants (G. Rogers and J. Paulson, 1983, Virology 127, 361-373). Whereas human isolates of this subtype strongly agglutinate enzymatically modified human erythrocytes containing the terminal SA alpha 2,6Gal sequence, avian and equine isolates preferentially agglutinate erythrocytes bearing the SA alpha 2, 3Gal sequence. As shown in this report, a glycoprotein found in horse serum, ...
Assessment of the sexual behavior of pregnant mares.
Hormones and behavior    December 1, 1983   Volume 17, Issue 4 405-413 doi: 10.1016/0018-506x(83)90049-1
Asa CS, Goldfoot DA, Ginther OJ.Pregnant mares (N = 12) were observed with a stallion from early gestation until parturition for sexual behavior. Observations were conducted for 20 min per day for 5 days each month from September until July. No mares exhibited full estrus and no intromissions or ejaculations occurred at any time during the study. Social interactions such as male approach and female/female mutual grooming occurred with greater mean frequency or duration in some months of spring and fall than in winter months. (P less than 0.05). None of the recorded behaviors differed by month of gestation. In a comparison of...
Reduction of the red blood cell mass of horses: toxic effect of heparin anticoagulant therapy.
American journal of veterinary research    December 1, 1983   Volume 44, Issue 12 2271-2276 
Duncan SG, Meyers KM, Reed SM.This study was designed to test the efficacy of heparin anticoagulant therapy in the horse and its effect on the formed elements of blood. Nine clinically normal, nontraumatized adult horses were subjected to 4 different heparin maintenance regimens (dosages of 320, 240, 160, and 40 U/kg of body weight). Porcine intestinal mucosa heparin (20,000 U/ml) was injected subcutaneously every 12 hours for 96 hours (total 9 times). A loading dose of one-third the maintenance dose was given IV just before the first heparin injection. Three control horses were given an equivalent volume of 0.9% saline so...
Mycotic abortions in equines.
Mykosen    December 1, 1983   Volume 26, Issue 12 612-614 
Monga DP, Tiwari SC, Prasad S.No abstract available
Effects of toxic doses of phenylbutazone in ponies.
American journal of veterinary research    December 1, 1983   Volume 44, Issue 12 2277-2279 
MacAllister CG.Toxic doses of phenylbutazone (10 mg/kg of body weight) were administered to 10 ponies once daily for 14 days. Clinical signs of toxicosis similar to those seen in other species included CNS depression, anorexia, oral ulcers, and soft feces. Six ponies died in 7 to 20 days; 1 pony was euthanatized during an acute abdominal crisis; and 3 ponies survived the study. At necropsy, the major lesions were oral and gastrointestinal ulcerations and renal changes.
Cerebrovascular response to acute decreases in arterial PO2. Wagerle LC, Orr JA, Shirer HW, Kiorpes AL, Fraser DB, DeSoignie RC.The purpose of these studies was to examine the time course of the cerebrovascular response to acute hypoxia in unanesthetized ponies. An electromagnetic flow transducer chronically placed on the internal carotid artery of the pony allowed continuous recording of internal carotid artery blood flow (ICBF) which has been shown to be representative of cerebral blood flow (CBF). The ponies were subjected to three levels of acute isocapnic hypoxia (PaO2 = 62, 44, and 39 mm Hg for hypoxia level I, II, and III, respectively), and the temporal and steady-state cerebrovascular response was examined. IC...