Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Losch K, Heinze W, Mieth K, Lender S.Pharmacokinetic data of sulphamerazine were recorded from eight heads each of calf, adult cattle, horse, and sheep, following intravenous application of Mebacid 200, and mathematical implications were discussed. Exponential excretion was recorded from all species, according to the following equation: c = B x e-k2 x t The most favourable pharmacokinetic parameters were recorded from calf.
Mattison DR, White NB, Nightingale MR.The polycyclic aromatic hydrocarbon (PAH) benzo(a)pyrene (BP) reduced the fertility of DBA/2N mice in a dose-dependent fashion. Control mice produced offspring at a rate of 0.91 pups/mouse per week. Treatment with BP at doses of 10, 100, 200, and 500 mg/kg decreased offspring production rates to 0.61, 0.20, zero and zero pups/mouse per week, respectively. BP also destroyed primordial oocytes in similarly treated mice. Treatment with BP at doses of 10, 50, 100, and 500 mg/kg destroyed 20%, 58%, 88%, and 100%, respectively, of the primordial oocytes in DBA/2N mouse ovaries. Dose-response curves ...
Mantovani A, Filippini I, Bergomi S.The present article completes the information already given in previous papers (Mantovani et al., 1976; Bellani et al., 1977; Mantovani, 1978) and is connected with the research on the infection of horses by Pampiglione et al. (1978). In September 1975 an epidemic of Trichinellosis involving at least 89 people was reported at Bagnolo in Piano (Reggio Emilia). This present article describes the epidemiological investigations. In the introductory part, the Trichinellosis outbreaks are summarized which were reported in Italy during this century along with research on domestic and wild animals. Th...
Mumford JA, Rossdale PD.Racehorses perform badly for many different reasons. Trainers often expect clinicians to determine the cause in individual cases and, more especially, where most of the immates of the stable are apparently affected by loss of form. Clinical examinations may reveal signs including fever, serous nasal discharge and the occasional cough. Haematology and blood biochemistry are commonly used aids to diagnosis in the field and may be helpful, but there is a need for facilities for virological investigations to be made readily available for use by clinicans as an adjunct to more commonplace laborator...
Booth LC, Oxender WD, Douglas RH, Woodley SL.A gonadotropin-releasing hormone (GnRH) was injected in mares given prostaglandin F2 alpha (PGF2 alpha) to induce luteolysis in an attempt to sunchronize ovulation. Pretreatment with estradiol-17 beta (E2-17 beta) was used to determine whether or not estradiol would enhance the release of luteinizing hormone (LH) after treatment with GnRH. Twelve mares were used in a balanced Latin square crossover design. Mares were injected with PGF2 alpha, treatment A; PGF2 alpha mgnRH, treatment B; or PGF2 alpha me2-17 beta mgnRH, treatment C. The interval +/- SEM from PGF2 alpha injection to estrus was 3....
Ferrante A, Thong YH.Results presented show that highly purified populations of mononuclear (MN) and polymorphonuclear (PMN) leucocytes can be obtained from horse blood by a procedure similar to that previously described for the separation of these leucocytes from human blood. This involved centrifugation of horse blood on a Ficoll-Hypaque medium with a density of 1.095 g/ml. The procedure required approximately 1 h for completion and resulted in the simultaneous preparation of MN (greater than 98% purity) and PMN (greater than 96% purity) leucocytes. Cell viability exceeded 95% and cells retained immunological fu...
Sentsui H, Kono Y.A seroepidemiological survey was performed on antibody against Getah virus in horses in Japan by the complement fixation test. The positive rate was 35 and 53% in two areas where an outbreak of the infectious disease was reported, whereas it was in a range of 3.3 to 24.2% in other areas, except in certain prefectures of the Kyushu district where a high positive rate was observed. In the Hokkaido district, the northernmost part of Japan, no reactors were found in horses under 6 years old, unlike in any other district. It was also suggested that Getah virus infection might have already been prev...
Lumsden JH, Rowe R, Mullen K.Reference hematology and biochemistry intervals are presented for a number of variables of clinical interest determined for blood samples obtained from 60 thoroughbred mares, 12 thoroughbred foals and 50 standardbred horses in training. The observations for each variable were examined for outliers and Gaussian distribution. Parametric analysis was used where the observations were Gaussian initially or after any of four transformations, otherwise nonparametric analysis was required for estimation of the 2.5 and 97.5 percentiles. Description of the sample collection procedures, laboratory method...
Tisserand JL, Ottin Pecchio M, Rollin G.The cellulolytic activity in the large intestine of the pony varies according to the form and the composition of the feed. This activity was measured on two caecal and ventral colon-cannulated ponies receiving the following 4 diets during four successive 6-week periods: --6 kg of hay, --4 kg of hay + 1 kg of oats, --6 kg of ground, pelleted hay. --5 kg of a ground, pelleted blend of 80 p. 100 hay and 20 p. 100 oats. Adding oats to a hay feed increased the cellulolytical activity in the caecum and the colon, whereas grinding and pelleting hay alone or hay enriched with oats diminished that acti...
Fernandez C, Möller G.After a primary immune response to the alpha 1-6 epitope of dextran B512, dextran high responder strains exhibit a specific inability to produce IgM and IgG antibodies against this epitope, although they gave an expected secondary response to horse erythrocytes. Spleen cells from dextran-primed and-suppressed mice responded well to dextran after transfer to lethally irradiated previously untreated mice, indicating that tolerance or exhaustive proliferation of dextran reactive B cells is not responsible. Thymus-dependent dextran-protein conjugates also induced specific suppression. Suppression ...
Tåmová B, Stumpa A, Zakopal J, Vĕzníková D, Mensík J.Equine influenza occurred in Czechoslovakia 14 years after the last epizootic in horses that had returned from abroad. Six strains A (Heq1Neq1) antigenically related to, but not identical with, strain A/eq/Praha/56 were isolated from 10 washings. Seroconversion was demonstrated with paired sera, but the antibody increase was more marked against the newly isolated strain.
Jemmerson R, Margoliash E.Seven populations of site-specific antibodies were isolated from each of three sera of rabbits immunized against glutaraldehyde-polymerized horse cytochrome c. The antibodies were separated using an immunoadsorption scheme which employed the following cytochromes c: horse, beef, guanaco, rabbit, mouse testicular, pigeon, and the cyanogen-bromide cleaved fragment of the rabbit protein containing residues 1 to 65. The monovalent, antigen-binding fragments of the antibodies (Fab') gave 1:1 stoichiometries with native horse cytochrome c in fluorescence quenching assays. Cross-reactivities with het...
van der Mey GJ.Horse-breeding in the Netherlands is briefly reviewed. Particular attention is paid to the number of foals of various breeds. Some effects of inbreeding in Friesian horses are discussed. As regards methods selection, attention is mainly paid to saddle horses. The role of veterinarians (from the point of view of selection for soundness) is described. Selection is based on the results of studies in the Faculty of Veterinary Medicine in Utrecht. A number of these results are reviewed.
Nakao T, Ohno-Fujitani T, Nakao M.Approximate molecular weights and the subunit structures of Na,K-ATPase from horse kidney were estimated by means of the combination of porous silica gel chromatography, laser light scattering (LS) and refractive index (RI) measurements in C12E8. When the enzymes were eluted with NaCl- or KCl-containing solution, 3 or 4 protein peaks, respectively were detected except that of low molecular weight range. These peaks were tentatively named Na-1, Na-2, Na-2', Na-3 (NaCl-containing eluents), K-1, K-2, K-3 (KCl-containing eluents), respectively. Na,K-ATPase and K-p-nitrophenylphosphatase activities...
Weigand K, Gerhards H, Köstlin R.The transmission of the laser beam trough flexible fibers enables an endoscopic application. Since this technique is minimal invasive and often does not require general anaesthesia there is an increasing interest in the use of laser techniques-for example in equine upper respiratory tract surgery. This paper gives a review about reported laser application in the different fields of veterinary surgery with emphasis on laser practice in dermatology, ophthalmology and endoscopic laser application.
Wilsher S, Ousey J, Allen WR.Abnormal cord attachment can be a manifestation of an inappropriate fixation position of the conceptus in the uterus, or it may result from disorientation of the conceptus post fixation. The potential for this resulting in fetal and neonatal compromise is reviewed in the light of previous reports and to which 3 cases within the authors' experience are added.
Riley CB, Jenvey CJ, Baker FJ, Corripio A. To determine if an ELISA for measurement of IgA in equine serum could be used to measure concentrations of IgA in foal faeces and to determine correlations with concentrations in the milk of the dam. Faeces from 20 Welsh Cob and Welsh Pony foals and milk from their dams were collected within 12 hours (Day 0) and at 6 days after parturition (Day 6). On Day 6, faeces could not be collected from 2/20 foals, and milk samples could not be collected from 3/20 mares. An equine IgA ELISA validated for serum and plasma was used to measure concentrations of IgA in all samples in triplicate. The preci...
Boyle AG.Respiratory distress in the horse and foal is an emergency. Managing equine respiratory distress in the field starts with appropriate assessment of the patient to determine whether the breathing obstruction stems from the upper or lower respiratory tract or is nonrespiratory in origin. From a thorough, but efficient, physical examination to point-of-care ultrasound and endoscopy, the veterinarian has many tools in the field to help diagnose the patient.
Gehlen H, Bubeck K, Stadler P.In 12 healthy warmblood horses (six trained and six untrained) the pulmonary wedge pressure and heart frequency was measured at rest and during a standardised exercise test on a treadmill. The mean pulmonary wedge pressure at rest was 14.53 +/- 2.36 mmHg. There was no significant difference in pulmonary wedge pressure either at rest or during exercise between trained and untrained horses. During walking (1.8 m/s) the mean pulmonary wedge pressure was 19.62 +/- 4.03 mmHg, during trotting (4 und 5 m/s) it was between 22.38 +/- 3.92 mmHg and 25.28 +/- 3.7 mmHg. During canter (6 m/s) and gallop (8...
Seren E, Tamanini C, Gaiani R, Bono G.Plasma concentrations of progesterone and 17 alpha-hydroxyprogesterone were high in the 2nd and 3rd months of gestation, but 20 alpha-dihydroprogesterone increased from a level of 2 ng/ml, during the first 3 months, to 10-15 ng/ml during months 5-10, to reach 80-120 ng/ml during the last 30 days before foaling.
McKinnon AO, Belden JO.A surgical technique involving reconstruction of the caudal vaginal vault was used to correct vesicovaginal reflux in 32 of 34 mares. After surgery, 22 of 24 mares became pregnant, and embryos were harvested for transfer from 6 of the other 10 mares. It was concluded that the procedure was safe and efficacious.
Meyer PK.The article reviews German anatomical terms applied to longer limb bones and their joints of the horse. The listed terms have been used in German veterinary and special veterinary anatomical hand- and textbooks since 1774; etymological remarks are made on some unusual words.
Brandstetter J, Stanek C, Hinterhofer C.The use of handmade particulate reinforced alloy horseshoes (MMC metal matrix composites) was tested in a field study on 15 riding and draught horses. All horseshoes have been tempered after having been manually forged and tested concerning their surface imperfection. Forging temperature ranged between 350 degrees and 420 degrees C. Horseshoes in series A consisted of particulate reinforced wrought alloy (22% Al2O3 in alloy matrix). 11 shoeing periods with a duration of mean = 49.7 days (sd = 13.6) were evaluated. Horseshoes in series B consisted of particulate reinforced foundry alloy (20% Si...
Levine RA, Hart AH, Wardlaw SC.Using quantitative buffy coat analysis (QBCA), rapid and accurate measurements can be made of the erythrocyte PCV, total WBC count, and platelet count, and the leukocyte population can be differentiated into total granulocytes (including quantitation of eosinophils), and lymphocytes and monocytes. The QBCA is performed by placing a blood sample (50 to 111 microliters) into a high-precision-bore microhematocrit tube that contains a freely moving, closely fitting, cylindrical plastic float. After centrifugation for 5 minutes, the buffy coat components separate by density. The plastic cylinder fl...
Wright IM, Smith MR.To report the technique, observations on fracture configurations and results of treatment by fixation lag screw following the fracture plane determined by an approach to the third metacarpal/metatarsal bone (MC3/MT3) that begins laterally over the metacarpo(metatarso)phalangeal joint and extends dorsally over the diaphysis of the bone. Methods: Case series. Methods: Thoroughbred horses (n=18) with propagating fractures of the medial condyle of MC3/MT3. Methods: Retrospective analysis of case records of horses with fractures of the medial condyle of MC3/MT3 that propagated sagittaly or in a spi...
Greiner EC.Potential methods of incriminating insects as the cause of insect hypersensitivity are presented. A listing of the biting midges known to attack horses in North America is presented also. An example of how species may be determined to be the cause of the hypersensitivity is given using data from a recent study in Florida. Light trap collections indicated the temporal and geographic distribution of potential contributing species and collections made by vacuuming horses further delineated species by proving they feed on horses and the correct locations on the horses to match lesion distribution....
Laan TT, Butler CM, Daha TJ, van Doorn DC, van Duijkeren E, Goehring LS, Houwers DJ, van Maanen C, Picavet T, Sloet van Oldruitenborgh-Oosterbaan MM.No abstract available
Dyson S.Methods of investigating horses with suspected shoulder lameness are described and discussed. The gait of shoulder lameness is characterised and compared with that of lower forelimb lameness. If lameness is slight, differentiation may be difficult, but if moderate, upper forelimb lameness usually results in shortening of the cranial phase of the stride and a low limb flight. Clinically, it may not be possible to differentiate between shoulder and elbow lameness without intra-articular anaesthesia. Practical aspects of intra-articular anaesthesia of the shoulder joint are reviewed. Synovial flu...
Divers TJ, Radcliffe RM, Cook VL, Bookbinder LC, Hurcombe SDA.Blood products, crystalloids, and colloid fluids are used in the medical treatment of severe hemorrhage in horses with a goal of providing sufficient blood flow and oxygen delivery to vital organs. The fluid treatments for hemorrhage will vary depending upon severity and duration and whether hemorrhage is controlled or uncontrolled. Methods: With acute and severe controlled hemorrhage, treatment is focused on rapidly increasing perfusion pressure and blood flow to vital organs. This can most easily be accomplished in field cases by the administration of hypertonic saline. If isotonic crystallo...
Reilly CA, Aust SD.An intracellular, membrane-bound enzyme exhibiting both p-phenylenediamine oxidase activity and ferrous iron oxidase activity was isolated with the plasma membrane fraction of horse heart and studied for its ability to load iron into ferritin. The ferroxidase activity of the tissue oxidase was stimulated approximately twofold by horse spleen apoferritin, and the iron was loaded into ferritin. The loading of iron into ferritin by the tissue oxidase was inhibited by anti-horse serum ceruloplasmin antibody. The stoichiometry of iron oxidation and oxygen consumption during iron loading into ferrit...