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Topic:Eyes

The study of equine eyes encompasses various anatomical, physiological, and pathological aspects of the horse's visual system. The equine eye is a complex organ adapted for a wide field of vision and low-light conditions, which is essential for the survival of prey animals. Key components include the cornea, lens, retina, and optic nerve, each playing a role in capturing and processing visual information. Common ocular conditions in horses include uveitis, cataracts, and corneal ulcers, which can affect vision and overall health. Diagnostic techniques such as ophthalmoscopy and ultrasonography are employed to assess eye health and detect abnormalities. This page compiles peer-reviewed research studies and scholarly articles that explore the anatomy, function, and diseases of the equine eye, as well as advancements in diagnostic and therapeutic approaches.
Ocular manifestations of systemic diseases.
The Veterinary clinics of North America. Equine practice    December 1, 1992   Volume 8, Issue 3 627-636 doi: 10.1016/s0749-0739(17)30445-5
Lavach JD.The diseases included in this article constitute a wide range of maladies that affect the horse. Certainly, the diseases that are known today to produce ocular lesions are just a few of what will be discovered if attending veterinarians always examine the eyes of patients with systemic diseases.
Eyelid and nasolacrimal disease.
The Veterinary clinics of North America. Equine practice    December 1, 1992   Volume 8, Issue 3 499-519 doi: 10.1016/s0749-0739(17)30438-8
Moore CP.An understanding of normal structure and function of the equine eyelid is essential to make an accurate diagnosis and appropriately treat equine eyelid diseases. Entropion, eyelid trauma, neoplasia, and nasolacrimal disorders are reviewed. Methods of diagnosis and treatment are presented.
Diagnosis and treatment of lens diseases.
The Veterinary clinics of North America. Equine practice    December 1, 1992   Volume 8, Issue 3 575-585 doi: 10.1016/s0749-0739(17)30442-x
McLaughlin SA, Whitley RD, Gilger BC.The lens represents a unique tissue in light of its embryologic development, retention of old cells and nuclear make-up, transparent nature, immune privileged status, and metabolic restrictions. Disorders of malformation and malposition occur, but cataract development is the most common and significant problem for owners and animals. Technologic and pharmacologic advances have allowed surgical removal of equine cataracts to become an acceptable alternative, capable of returning a visually impaired horse to a functional status. Uveal inflammation represents the greatest threat to successful sur...
Normal equine ocular anatomy and eye examination.
The Veterinary clinics of North America. Equine practice    December 1, 1992   Volume 8, Issue 3 427-449 doi: 10.1016/s0749-0739(17)30434-0
Cooley PL.When compared with small domestic animals, the horse has unique ocular characteristics (complete bony orbit, well-developed eyelid muscles, a nasal and temporal gray limbal line, granulae iridica, paurangiotic fundus). Knowledge of normal equine ocular anatomy is essential for ocular lesion interpretation. It is important to obtain a full history and general examination before sedation, nerve blocks, or other diagnostic ophthalmic tests are performed. All ocular examinations should include a systematic evaluation of both the anterior and posterior segments. Selection of other diagnostic tests ...
Principles of therapeutics.
The Veterinary clinics of North America. Equine practice    December 1, 1992   Volume 8, Issue 3 479-497 doi: 10.1016/s0749-0739(17)30437-6
Miller TR.Topical administration of drugs is the treatment of choice for diseases of the anterior segment. Drug levels attained by this means are usually of short duration, however, necessitating frequent therapy or continuous perfusion if prolonged drug levels are required. A drug-delivery device (collagen shield or contact lens) or subconjunctival injections can be used to augment topical therapy if frequent treatment is not possible. Subconjunctival injections are recommended for drugs that have low solubility and, hence, low corneal penetration. Retrobulbar injections are seldom indicated, except fo...
Medical evaluation of the eye relevant to purchase.
The Veterinary clinics of North America. Equine practice    August 1, 1992   Volume 8, Issue 2 365-375 doi: 10.1016/s0749-0739(17)30457-1
Lavach D.Performance and pleasure horses depend upon their ability to see and assess the environment. Thus, the veterinarian must be able to examine the eyes and recognize abnormalities so that the owner or purchaser can be informed about the visual status and prognosis for the horse's vision. If the veterinarian encounters suspicious or abnormal findings during the examination, a more detailed examination and/or referral to a veterinary ophthalmologist can be recommended to the owner or purchaser.
Comparison of applanation tonometers in dogs and horses.
Journal of the American Veterinary Medical Association    August 1, 1992   Volume 201, Issue 3 430-433 
Dziezyc J, Millichamp NJ, Smith WB.Two Mackay-Marg tonometers and 2 Tono-Pen tonometers were evaluated in eyes in which intraocular pressure (IOP) had been altered and measured by use of a manometer. Eyes of anesthetized dogs and enucleated horse eyes were used. Compared with the manometer, none of the tonometers accurately measured IOP over the range between 0 and 100 mm of Hg. However at manometer measurements from 0 to 30 mm of Hg, several of the tonometers accurately measured IOP. In addition, significant differences were observed when the measurement accuracy of one tonometer was compared with that of another, especially a...
[Two rare lens abnormalities in horses].
Tierarztliche Praxis    June 1, 1992   Volume 20, Issue 3 282-286 
Gerhards H, Werry H, Deegen E, Köstlin RG.Coloboma and ectopia of the crystalline lens are rarely encountered or diagnosed congenital defects of the equine eye. The clinical and ophthalmoscopic features of a congenital coloboma of the lens in a 3 year old Hanoverian stallion and of an ectopic lens in a 6-month old Hanoverian filly are described and depicted. In the stallion, the lens coloboma was associated with a partial coloboma of the zonules, and in the filly, the ectopic lens was small and spherical (microphakia, spherophakia) and associated with syneresis of and small floaters in the vitreous. Although it cannot be excluded that...
Biochemical analysis by SDS-PAGE and western blotting of the antigenic relationship between Leptospira and equine ocular tissues.
Veterinary immunology and immunopathology    June 1, 1992   Volume 33, Issue 1-2 179-185 doi: 10.1016/0165-2427(92)90045-r
Parma AE, Cerone SI, Sansinanea SA.The antigenic relationship between Leptospira interrogans, equine cornea and lens was previously noted in our studies. Serum antibodies from horses inoculated with serovars wolffi, pomona, icterohaemorrhagiae, and tarassovi, were able to bind to five antigenic fractions from both cornea and lens, as demonstrated by immunoblotting. These antigens seem to be made up of protein and carbohydrates. After treatment with periodate for cleavage of glycoside ring structures, those fractions kept their condition of target for anti-Leptospira antibodies. Nevertheless, all fractions lost that condition af...
Evaluation of zones of iris hypoplasia in horses and ponies.
Journal of the American Veterinary Medical Association    April 1, 1992   Volume 200, Issue 7 940-942 
Buyukmihci NC, MacMillan A, Scagliotti RH.Mass-like lesions of the iris were evaluated in 15 horses or ponies of various ages and breeds. Breed or gender predilection was not found. These lesions were most often found in blue irides at the 12 o'clock region. Because the lesions transilluminated and changed shape rapidly with changes in pupillary size, they were hypothesized to be zones of iris hypoplasia. Histologic evaluation of one specimen supported this interpretation. The lesions were not associated with any other ocular or systemic abnormality.
Repair of superior palpebral defect in a horse by use of silicone subdermal implant.
Journal of the American Veterinary Medical Association    March 15, 1992   Volume 200, Issue 6 821-824 
Wilkie DA.A silicone subdermal implant was used in the surgical repair of a superior palpebral defect in a horse. The right superior palpebra was missing from the lateral canthus superiorly to the 1 o'clock position, and a corneal ulcer, anterior uveitis, and right micropalpebral fissure also were observed. Lateral canthotomy and canthoplasty were performed to enlarge the palpebral fissure, and a silicone implant was inserted in the superior palpebra to replace the missing tarsal plate. These procedures resulted in a successful reconstruction, with improvement of palpebral function.
[Adenoma of the pigmented epithelium of the iris with endothelialization and descemetization in the horse].
Zentralblatt fur Veterinarmedizin. Reihe A    November 1, 1991   Volume 38, Issue 9 652-659 
Daicker B, Gywat L, Keller M, Spiess B, Brückner R.The authors describe peculiar tumors with brown-white piebald anterior surface, which had grown bilaterally from the corpora nigra (C.N.) of an adult horse and occluded the pupils. The surgical procedure for removing the larger tumor and the postoperative treatment are described. The findings by light and electron microscopy suggest that the tumor represent a so-called adenoma of the iris pigment epithelium. The white patches on its surface consist of newly formed Descemet-like material produced by displaced corneal endothelial cells, which have probably grown on the tumor after contact with t...
Anterior uveal melanoma, with secondary keratitis, cataract, and glaucoma, in a horse.
Journal of the American Veterinary Medical Association    October 15, 1991   Volume 199, Issue 8 1049-1050 
Davidson HJ, Blanchard GL, Wheeler CA, Render JA.Intraocular melanoma was diagnosed in a 13-year-old horse. Secondary clinical findings included keratitis, cataract, and glaucoma. The eye was enucleated. Follow-up information did not give an indication of metastatic disease.
Detection of Toxoplasma gondii in equine eyes.
The Veterinary record    August 10, 1991   Volume 129, Issue 6 128 doi: 10.1136/vr.129.6.128-a
Turner CB, Savva D.No abstract available
Traumatology of the equine eye.
Tijdschrift voor diergeneeskunde    April 1, 1991   Volume 116 Suppl 1 43S-45S 
Van der Velden MA.No abstract available
Glaucoma in horses.
Veterinary pathology    January 1, 1991   Volume 28, Issue 1 74-78 doi: 10.1177/030098589102800110
Wilcock BP, Brooks DE, Latimer CA.No abstract available
[Immunotherapy of squamous cell carcinoma of the bovine eye and of equine sarcoid].
Tijdschrift voor diergeneeskunde    December 15, 1990   Volume 115, Issue 24 1149-1155 
Klein WR.Squamous cell carcinomas of the bovine eye and equine sarcoids are briefly reviewed. A single injection of BCG into the tumour results in permanent regression of the lesion in 37 per cent of the cattle, regression followed by recurrence of the tumour in 26 per cent and in progressive growth of the tumour in 37 per cent of the cases. Recurrence may be prevented by repeated injection into the lesion. From 50 to 60 per cent of the cows will remain free from tumours. Equine sarcoids show a complete regression in 70-80 per cent of the cases. Tumours on the limbs show a less satisfactory response (l...
Proliferative optic neuropathy in a horse caused by a granular cell tumour.
Equine veterinary journal. Supplement    September 1, 1990   Issue 10 69-72 doi: 10.1111/j.2042-3306.1990.tb04716.x
Riis RC, Rebhun WC.No abstract available
The equine fundus. III: Pathological variants.
Equine veterinary journal. Supplement    September 1, 1990   Issue 10 55-61 doi: 10.1111/j.2042-3306.1990.tb04713.x
Matthews AG, Crispin SM, Parker J.A wide range of ophthalmoscopic variants are encountered during routine examination of the horse. Some result from minor anatomical anomalies, cause no significant effect on vision and may be considered to lie within the limits of 'biological normality'. Others are a consequence of pathological disruption of the anatomical integrity of the fundus, and may directly or indirectly affect the neurosensory retina and produce some degree of visual deficit. This paper illustrates the ophthalmoscopic appearance of a number of pathological variants of the anatomic fundus, and discusses their possible e...
Bilateral colobomas involving the optic discs in a quarterhorse.
Equine veterinary journal. Supplement    September 1, 1990   Issue 10 39-41 doi: 10.1111/j.2042-3306.1990.tb04710.x
Wheeler CA, Collier LL.THIS report describes bilateral colobomas of the optic discs with associated aberrations in ocular differentiation • and unusual hypopigmentation of the uveal tissues.
Tonometric and tonographic studies in the normal pony eye.
Equine veterinary journal. Supplement    September 1, 1990   Issue 10 36-38 doi: 10.1111/j.2042-3306.1990.tb04709.x
Smith PJ, Gum GG, Whitley RD, Samuelson DA, Brooks DE, Garcia-Sanchez GA.Tonometric and tonographic techniques were evaluated in the normal pony and compared to other species. Applanation tonometry was utilised to calculate the ocular ridigity of the normal equine eye. The mean intraocular pressure for the pony eye was established as 23.5 mm Hg (sd +/- 4.5). Comparing the non-anaesthetised and anaesthetised pony eye (xylazine-ketamine and glycerol guaiacolate) no significant change in intraocular pressure occurred (P < 0.49). Mean aqueous outflow facility was 0.88 microliter/min/mm Hg (sd +/- 0.65) which is significantly higher (P < 0.01) than the canine and ...
The equine fundus. II: Normal anatomical variants and colobomata.
Equine veterinary journal. Supplement    September 1, 1990   Issue 10 50-54 doi: 10.1111/j.2042-3306.1990.tb04712.x
Matthews AG, Crispin SM, Parker J.A wide range of fundic variants are encountered during routine ophthalmoscopic examination of visually normal horses, often causing the examiner difficulty in assessing their clinical significance. Many of these are anatomical variants having no significant effect on visual function, and lie within the limits of normality in the horse. This paper illustrates this range of variants and discusses their anatomical basis and physiological consequences. Colobomata are non-progressive discontinuities in the structure of the anatomic fundus, occasionally noted as incidental findings during ophthalmos...
Nutritionally variant streptococci associated with corneal ulcers in horses: 35 cases (1982-1988).
Journal of the American Veterinary Medical Association    September 1, 1990   Volume 197, Issue 5 624-626 
da Silva Curiel JM, Murphy CJ, Jang SS, Bellhorn RW.Nutritionally variant streptococci (NVS) are nutritionally deficient viridans streptococci that require pyridoxal for growth. Although NVS are pathogenic in human beings, they have not been considered to be pathogenic in domestic animals. In 1982 and 1983, 24 isolates of NVS were recovered from horses with ulcerative keratitis. A retrospective study was done to determine the incidence of NVS in horses with corneal disease. The medical records of 249 horses (259 eyes) examined for clinical signs of corneal disease were reviewed. Nutritionally variant streptococci were isolated from approximatel...
Peripheral corneal ulcers in the horse.
Equine veterinary journal. Supplement    September 1, 1990   Issue 10 18-21 doi: 10.1111/j.2042-3306.1990.tb04704.x
Dice PF, Cooley PL.This report involves a retrospective study of five horses with an unusual form of progressive peripheral corneal ulcers. These ulcers were located at the perilimbal region of the cornea and spread both centripetally to mid periphery and circumferentially. Lipping of the epithelial edge was observed often. The depth ranged from superficial to mid stroma. Patients ranged from two and a half to eight years, both sexes, and were referred after a variety of antibacterial therapy. Histories were similar in that all ulcers were initially located adjacent to the limbus in one or more quadrants. No tra...
Follow-up report of a case of surgical aphakia with an analysis of equine visual function.
Equine veterinary journal. Supplement    September 1, 1990   Issue 10 91-93 doi: 10.1111/j.2042-3306.1990.tb04721.x
Farrall H, Handscombe MC.More work is necessary to establish corneal dimensions and retinal structure and neural organisation in the equine eye. This paper reports a case of surgical management of bilateral cataracts in a pony and the results of a survey of refractive error in normal horses. Aspects of accommodation are discussed. It is suggested that a difference in retinal receptor organisation between horse and human eyes could explain the good visual performance of the aphakic pony; and that the degree of blurring of vision in the aphakic situation is less, both in absolute terms and in proportion to presumed norm...
The morphology of the equine iridocorneal angle: a light and scanning electron microscopic study.
Equine veterinary journal. Supplement    September 1, 1990   Issue 10 30-35 doi: 10.1111/j.2042-3306.1990.tb04708.x
De Geest JP, Lauwers H, Simoens P, De Schaepdrijver L.The present investigation of 20 equine eyes shows that the iridocorneal angle of the horse is characterised by a very distinct pectinate ligament and a large ciliary cleft. The pectinate ligament consists of long and broad pigmented trabeculae which form a firm, flat and dense network that encircles the eye. On meridional sections, the ciliary cleft is visible as a wide triangular space comprising the trabecular meshwork which consists of two parts. The inner part is the larger and forms a three-dimensional network of large pigmented trabeculae with very wide intertrabecular spaces. The outer ...
Treatment of advanced squamous cell carcinomas involving the equine cornea.
Veterinary surgery : VS    July 1, 1990   Volume 19, Issue 4 297-302 doi: 10.1111/j.1532-950x.1990.tb01191.x
Rebhun WC.Corneal squamous cell carcinomas with surface areas of more than 2.0 cm were diagnosed in 26 eyes of 25 horses. The depth of the lesion into the corneal stroma and involvement of the ocular adnexa were important determinants for surgical treatment. Corneal tumors that extended into adjacent palpebral conjunctiva, eyelid, or orbit were not amenable to complete excision, while those that involved only cornea and bulbar conjunctiva were treated surgically by keratectomy and beta radiation. Initial treatment was keratectomy followed by beta radiation on 24 eyes and enucleation of two eyes. Twenty ...
Nonulcerative keratouveitis in five horses.
Journal of the American Veterinary Medical Association    June 15, 1990   Volume 196, Issue 12 1985-1991 
Brooks DE, Millichamp NJ, Peterson MG, Laratta LJ, Morgan RV, Dziezyc J.Five horses with severe nonulcerative keratouveitis had corneal lesions characterized by a pink stromal infiltrate that initially appeared in the stroma near the limbus. Unremitting iridocyclitis also was evident. In 3 horses, microscopic lesions consisted of marked corneal stromal fibrosis, with mild to severe inflammatory cellular infiltration. Corticosteroids and mydriatic/cycloplegics applied topically and corticosteroids and nonsteroidal anti-inflammatory medications administered parenterally were used with varying degrees of success to control pain and retain vision.
Evaluation of two applanation tonometers in horses.
American journal of veterinary research    June 1, 1990   Volume 51, Issue 6 935-937 
Miller PE, Pickett JP, Majors LJ.Comparisons were made of measurements obtained in horses, using 2 applanation tonometers in vivo and in vitro. In vitro comparisons indicated that although neither instrument accurately recorded intraocular pressure (IOP), compared with manometric measurements, results of both instruments indicated linear digression from manometric IOP values that could readily be corrected, thereby accurately estimating IOP in horses. For tonometer 1 (MacKay-Marg), calculated actual IOP = 1.48 - 0.9 mm of Hg; and for tonometer 2 (Tono-Pen), calculated actual IOP = 1.38 + 2.3 mm of Hg. The coefficients of dete...
Combined treatment of ocular squamous cell carcinoma in a horse, using radiofrequency hyperthermia and interstitial 198Au implants.
Journal of the American Veterinary Medical Association    June 1, 1990   Volume 196, Issue 11 1831-1833 
Wilkie DA, Burt JK.Unilateral ocular squamous cell carcinoma in a horse was treated effectively with a combination of repeated radiofrequency hyperthermia and interstitial radiotherapy. These 2 modalities of treatment are synergistic. Interstitial irradiation was achieved, using 198Au implants to deliver a total dose of approximately 5,000 rads/implant over an area of 1 cm2. Radio frequency hyperthermia was repeated 3 times, and radiotherapy was used twice. Treatment resulted in complete regression of the tumor, and ocular complications have not been seen.
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