"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Hoffman AM, Viel L, Staempfli HR, Muckle CA, Yager JA.One indication for referral of horses to veterinary hospitals is for diagnosis of the microbiologic cause of pneumonia, particularly when the initial treatment fails. Although endoscopic methods have long been available for microbiologic sample collection, accuracy of these methods under these conditions have not been studied in detail. We compared the bacteria isolated from samples obtained by bronchoalveolar lavage (BAL) with those obtained by protected catheter brush (PCB) from foals with unilateral pneumonia induced by inoculation with Klebsiella pneumoniae. As part of previously described...
Epe C, Ising-Volmer S, Stoye M.The results of the coproscopical examinations in horses, dogs, cats and hedgehogs between 1984 and 1991 are presented. In 9192 samples from horses 55.5% stages of strongylids, 4.0% of Parascaris equorum, 2.2% of anoplocephalids, 1.6% Strongyloides westeri, 0.7% of Oxyuris equi, 0.6% of Eimeria leuckarti, 0.2% of Fasciola hepatica and 0.04% of Dictyocaulus arnfieldi were found. In 48.0% of the 46 samples from donkeys eggs from strongylids were detected, in 17.4% larvae from Dictyocaulus arnfieldi, in 2.2% eggs from Strongyloides westeri, Parascaris equorum and oocysts from Eimeria leuckarti, re...
Lopez-Plana C, Sautet JY, Ruberte J.Three adductor muscles of the larynx, the cricoarytenoideus lateralis (CAL), the arytenoideus transversus (AT) and the ventricularis (Ve), from 36 horses were examined histologically. The neurogenic changes seen in each muscle were evaluated qualitatively. In addition, in 6 horses with clinical and subclinical signs of neurogenic atrophy, measurements of muscle fibre area were performed. Neurogenic changes observed in the Ve were less than in CAL and AT. Measurements of muscle fibre area also demonstrated that CAL and AT showed a wider range of pathological changes than did Ve. The results sho...
Gillis CL, Meagher DM, Pool RR, Stover SM, Craychee TJ, Willits N.The forelimb superficial digital flexor (SDF) tendons of 6 Thoroughbreds were examined clinically and ultrasonographically during the first 4 months of race training. Sonograms were interpreted clinically and by use of computer-aided analysis. Tendon tissue from all horses was examined histologically at the end of the study. Computer-aided analysis of sonograms of the SDF tendons revealed trends toward an increase in mean cross-sectional area and a decrease in mean echogenicity over time with training. An inverse relation was found between increase in cross-sectional area and decrease in mean ...
Steffey EP, Giri SN, Dunlop CI, Cullen LK, Hodgson DS, Willits N.Six healthy horses were anaesthetised with halothane (1.2 times the horse minimal alveolar concentration) in oxygen for more than 12 hours. Serum bilirubin, aspartate aminotransferase, alkaline phosphatase and L-iditol dehydrogenase values were significantly (P < 0.05) increased for up to nine days after anaesthesia. These changes suggest an anaesthesia related liver dysfunction. Creatine kinase increased to an average of more than 1400 IU litre-1 24 hours after anaesthesia and this change is indicative of muscle cell disruption. Renal-associated biochemical results, (that is serum creatinine ...
Foerner JJ, Ringle MJ, Junkins DS, Fischer AT, MacHarg MA, Phillips TN.A 7-year-old Thoroughbred mare underwent exploratory celiotomy for diagnosis and treatment of colic. An irreducible herniation of the large colon through the epiploic foramen was found. To reduce the hernia, the pelvic flexure was transected and the ends of the large colon were closed. The intercolonic mesentery was divided, and unaffected left ventral colon was moved into the epiploic foramen, providing sufficient space so that affected left dorsal colon could be reduced. The affected left ventral colon was then reduced and the diseased portion of both colons was resected. The colons were res...
Maxson AD, Giger U, Sweeney CR, Tomasic M, Saik JE, Donawick WJ, Cothran EG.Anemia that was secondary to ovarian hemorrhage in a 4-year-old miniature horse mare was treated prior to laparotomy with polymerized ultrapurified bovine hemoglobin (PUBH). Two previous whole-blood transfusions had resulted in acute transfusion reaction, and a suitable blood donor could not be found among 9 horses, necessitating use of the blood substitute. Subsequent blood typing revealed the mare to be Aa-negative, with allo-antibodies against Aa in serum. Serious adverse reactions were not observed after infusion of PUBH, and the mare recovered. Although the safety and efficacy of using PU...
Magnarelli LA, Anderson JF.In a retrospective study, indirect fluorescent-antibody staining methods were used to detect immunoglobulins to Ehrlichia canis and Ehrlichia risticii in canine and equine sera that had originally been analyzed for antibodies to Borrelia burgdorferi. Analyses of 60 dog serum specimens collected in Connecticut and New York State during 1986 revealed antibodies to E. canis in 7 (11.7%) specimens; titration endpoints ranged from 1:40 to 1:320. Three of these dogs had anemia. Of the 187 equine serum specimens obtained in Connecticut during 1985 and analyzed by indirect fluorescent-antibody stainin...
Freeman KP, Roszel JF, McClure JM, Mannsman R, Patton PE, Naile S.Thirty-six transtracheal washing (TTW) and 12 bronchoalveolar lavage (BAL) specimens collected in clinical practice from horses with and without respiratory disease were reviewed. Cytological features were considered in accordance with the presenting complaint, clinical signs, clinical diagnoses, microbiological, radiographic and/or endoscopic findings, therapy, and response to therapy. The trichrome-stained TTW and BAL specimens were useful in interpreting the results of concurrent microbiological cultures, and determining whether a condition was present based on occurrence of typical cytolog...
Regodon S, Franco A, Lignereux Y, Redondo E.A technique is described for catheterisation of the ventricular recess within the olfactory bulb of the horse. Twelve adult horses were used. The olfactory recess is in the frontal region, 42 +/- 3 mm below the skin, on the line joining the supraorbital foramina, and approximately 18 +/- 2 mm from the midline. The approach is relatively easy under normal experimental conditions.
Yurdaydin N, Tekin N, Gülyüz F, Aksu A, Klug E.An Arab broodmare herd of 30 mares age ranging from 4 to 12 years was grouped into 3 groups (group A, B, C) with 10 mares each and exposed to three different methods of cycle synchronisation. Group A mares received two PGF2 alpha injections 14 days apart. Group B mares got additionally 2,500 IU of hCG 5 days after second prostaglandin application. Group C consisted of mares which had foaled in a synchrony of one week and got a PGF2 alpha injection 3 weeks after parturition. All the mares responding to synchronisation were inseminated closely to ovulation detected by serial rectal palpations wi...
Ruggles AJ, Ross MW, Freeman DE.Sixteen horses with suspected paranasal sinus disease had endoscopic examination of the paranasal sinuses with a 4.0 mm arthroscope either while standing and sedated (14 horses) or under general anesthesia (two horses). Endoscopic diagnosis included sinusitis (four horses), sinus cyst (three horses), hemorrhage (three horses), neoplasia (three horses), and tooth root abnormalities (two horses). No abnormalities were detected in one horse. Endoscopic findings concurred with the radiographic findings in 13 horses (81%). Samples of sinus contents for bacteriologic (eight horses) and histologic ex...
van den Belt AJ, Keg PR, Kik KJ, Barneveld A.An in vitro study was carried out to define the correlation between the dose and distribution of intratendinous fluid injections in the different flexor tendons/ligaments of the palmar/plantar, metacarpal/metatarsal region of the horse. Injection of 0.1-0.2 ml resulted in a local intratendinous fluid depot showing minimal abaxial spreading and more extensive proximodistal expansion. If 0.3-0.5 ml was injected the abaxial spreading remained minimal but the proximodistal expansion increased significantly, the depots in the axial proximal, mid and distal region flowing together. Also minimal peri...
Wright IM.The clinical features are reported from 118 horses (mean age 9.2 years) which were diagnosed as suffering from navicular disease using predetermined criteria. The animals were used for a variety of purposes and had been lame for periods between 1 and 72 months. The majority of cases (84.7%) had been treated using various techniques before evaluation. The severity of lameness was related to the duration of clinical signs: 78% of horses were bilaterally affected but there was no left:right limb predominance. Broken foot/pastern axes were recorded in 75% of horses while 45% also exhibited mediola...
Bowker RM, Brewer AM, Vex KB, Guida LA, Linder KE, Sonea IM, Stinson AW.Two types of sensory receptors were located in the equine foot, using anatomic techniques. Histologic examination of stained hoof sections revealed lamellated corpuscles in the hoof dermis, which had many of the morphologic characteristics of Pacinian corpuscles. These sensory receptors were restricted to the palmar (caudal) aspects of the solar dermis of the heel. A second type of receptor was detected by use of immunocytochemistry, indicating apparently naked nerve endings containing the neuropeptide calcitonin gene-related peptide-like immunoreactivity in skin, solar dermal tubules, and the...
Wright IM.The 118 horses diagnosed as suffering from navicular disease by prospective criteria were treated by desmotomy of the ligamenta sesamoidea collateralia (navicular suspensory desmotomy). Three techniques were used and a standard post-operative programme was followed with clinical and radiological evaluations at 6-monthly intervals for periods of 6-36 months after surgery. At 6 and 36 months after treatment, 76% and 42.9% of horses were sound respectively. The clinical features of age, period of lameness, severity of lameness and angular limb deformities adversely affected response to surgery. T...
Salvioli G, Gaetti E, Panini R, Lugli R, Pradelli JM.To evaluate why hemolysis of red blood cells (RBC) by bile acids varies in different mammalian species, we determined the mean corpuscular volume (MCV), lipid content and the concentrations of the conjugates of deoxycholate and of NaCl inducing 50% hemolysis of RBC from healthy humans, pigs, horses, cows, sheep and jaundiced humans. A volume of 0.05 mL of washed RBC at 1% hematocrit, which has the same lipid content but different phospholipid composition and number of erythrocytes (owing to the variable MCV), was incubated in taurodeoxycholate (TDC) solution (0-5 mM) to determine the TDC conce...
López-Plana C, Sautet JY, Pons J, Navarro G.Quantitative measurements were made on cross-sectional preparations of the distal part of the recurrent laryngeal nerve (RLN) from nine young mixed-breed horses to establish reference values for the total number of myelinated fibres, mean fibre diameter and percentage of thickest fibres (over 9.5 microns) and to delineate diameter distribution curves. The total number of myelinated fibres, mean fibre diameter and percentage of thickest fibres for the left RLN were significantly lower than those of the right RLN (P < 0.005). The distribution of fibres was unimodal. The fibre diameter ranged ...
Baxter GM, Jackman BR, Eades SC, Tyler DE.Intra-abdominal adhesions were created by localized serosal trauma in 11 adult ponies at three locations on the small intestine. Six ponies received verapamil hydrochloride (0.2 mg/kg) subcutaneously every eight hours for three days, and five ponies received an equal volume of saline solution at the same intervals. The investigators were not informed which treatments the ponies received. Systolic, diastolic, and mean carotid arterial pressures and heart rates were measured six hours before surgery, and then 0.5, 1, 1.5, and 8 hours after the first treatment on each day for three days. One pony...
Leach DH.The future directions of navicular disease research are unclear. Often researchers investigate only one of the multitude of factors likely to be important in understanding the disease. Two exceptions to this is work done by Wright in this issue of EVJ and by MacGregor (1988) who compared a number of the treatment regimens (e.g. rest, warfarin, isoxsuprine, shoeing with egg bars) and found that approximately 75% of the horses improved in their performance. Perhaps this percentage of 'recovered' horses from this disease is what can be realistically expected, as often horses with navicular diseas...
Freeman DE, Staller GS, Maxson AD, Sweeney CR.A mare with hemorrhage caused by guttural pouch mycosis was treated by insertion of a balloon-tipped catheter into the left internal carotid artery. During recovery from general anesthesia, the mare had profuse epistaxis, and was anesthetized again to determine the site of hemorrhage. The affected guttural pouch was opened to confirm that hemorrhage was from the left internal carotid artery. The mare was euthanatized, and, at necropsy, the balloon catheter was found in an aberrant branch that arose from the internal carotid artery and joined the basilar artery. The mycotic plaque was on the le...
Troedsson MH, Liu IK, Ing M, Pascoe J, Thurmond M.The electrical myometrial activity of three mares with a documented increased susceptibility to chronic uterine infection (CUI) and three mares considered to be resistant to CUI was investigated. Electrodes were surgically implanted in the myometrium of the mares and electrical activity was monitored by a Grass polygraph. Oestrus was determined by transrectal ultrasonography of the reproductive tract and teasing of the mares with a stallion. Findings were confirmed by blood progesterone concentrations 35 mm was detected, the uterus was infused with a genital strain of 5 x 10(6) Streptococcus ...
Pösö AR, Essén-Gustavsson B, Persson SG.Plasma concentrations of lactate, amino acids, ammonia and products of purine catabolism were studied before, during and after a standardised incremental exercise test in 29 Standardbred trotters admitted to the clinic for exercise tolerance testing. According to their red cell volume the horses were divided into red cell normovolaemic and red cell hypervolaemic (polycythaemic) groups. The exercise-response curve for taurine differed significantly in the two groups, whereas all the other amino acids behaved similarly. The [branched-chain amino acid]/[alanine] ratio, a proposed indicator for th...
Perkins NR, Threlfall WR, Ottobre JS.Existence of ultradian variation in serum progesterone concentration and the relation between progesterone and luteinizing hormone (LH) secretory patterns were investigated in nonpregnant and pregnant mares. Blood samples were taken every 15 minutes for a 24-hour period on day 8 of the estrous cycle and day 18 of pregnancy, respectively. Progesterone and LH concentrations were determined by radioimmunoassay. Progesterone was secreted in pulsatile manner in nonpregnant and pregnant mares. Luteinizing hormone also was secreted in a pulsatile manner in both groups of mares. There was little tempo...
Wright IM.Dorsoproximal-palmarodistal oblique, lateromedial and palmaroproximal-palmarodistal oblique radiographic projections were used with standard techniques to examine 118 horses with clinical signs of navicular disease. All radiological features which have previously been reported as significant changes in the navicular bones of horses with navicular disease were recorded. Comparisons were made between these features in lame limbs and sound limbs in unilaterally lame horses and most lame limbs and least lame limbs in bilateral but asymmetrically lame animals. Their relationship to the degree of la...
Apt W, Aguilera X, Vega F, Alcaíno H, Zulantay I, Apt P, González V, Retamal C, Rodríguez J, Sandoval J.This study sought to estimate for the first time the prevalence of fascioliasis among the rural population in the Chilean provinces of Curico, Talca, and Linares, while also determining the disease's prevalence among horses and wild rabbits in Curico and Talca and among pigs in Talca. From January 1986 to December 1990 a randomly selected sample of 5,861 persons in the three provinces was given intradermal, complement-fixation, double-diffusion, and immunoelectrophoresis tests to detect antibody to Fasciola hepatica. In addition, the ELISA test was used in Talca and Linares. Fecal specimens fr...
Wagstaff KH, Dickson SL, Bailey A.The history of WEE surveillance in Utah is reviewed, beginning with the 1933 outbreak involving 3,958 horses. The step by step formation of the Utah Mosquito Abatement Associations surveillance program from 1957 to the present is discussed. Results of an enlarged sentinel chicken flock surveillance program in Utah during 1983 (3 sero-conversions in September), 1984 and 1985 (no sero-conversion) show the lack of WEE activity in the surveillance area.
Arighi M, Miller CR, Pennock PW.Scapulohumeral arthrodesis was performed successfully as treatment for severe degenerative arthritis in a 62-kg miniature horse. Using an approach similar to that used for a dog, this horse's scapulohumeral joint was opened, the cartilage was removed, and the site was stabilized, using an 11-hole narrow dynamic compression plate. Fusion was uncomplicated. The stallion became a successful pasture-breeding animal.
van Buiten A, Westers P, Colenbrander B.The "effect" of stallion, mare and management-related factors on the odds of pregnancy per cycle in the horse were identified and quantified from the breeding records of Dutch Warmblood (n=4491), Friesian (n=1467) and Shetland-pony mares (n=3267) mated either naturally or by artificial insemination to one of the 88 stallions between 1992 and 1996. A mare was considered to be pregnant when she did not return to oestrous within 28 days of the last insemination. For Dutch Warmblood horses, the percentage of mares that did not return for service within 28 days (NR28) varied between studfarms and r...
Todhunter KH, Cawdell-Smith AJ, Bryden WL, Perkins NR, Begg AP.Pregnant mares were experimentally exposed to whole caterpillar or exoskeleton of the Processionary caterpillar (Ochrogaster lunifer) via gavage. Tissues were collected from resulting abortions and near or full-term pregnancies consisting of 13 aborted fetuses, 3 fetuses from treated euthanized mares, membranes of 5 foals, and organs from 3 foals. Three control membranes and 1 control fetus and membranes were examined. Caterpillar setal fragments were present in the allantochorion of the 3 fetuses from the euthanized mares and 11 of 12 aborted fetuses (92%) embedded in the chorion (villi or st...
Hazard GH, Hughes KL, Penson PJ.Contagious equine metritis (CEM) was first diagnosed in Australia in August 1977 and it has since been found on 6 farms in 3 states, having been isolated from about 24 mares and 2 stallions. Details are given of the epidemiology and control procedures used to combat CEM on one farm. Difficulty was experience in successfully treating one infected stallion; this was thought to be associated with inadequate cleaning and treating of the diverticulum of the urethral fossa. Introduction of the disease has had far-reaching consequences and may well result in the adoption of routine bacteriological te...
Campbell ML, England GC.Uterine contractions may play an important role in the transportation of spermatozoa towards the site of fertilisation in the oviduct of mares. M-mode ultrasound was used to measure the number, amplitude and duration of uterine contractions in each uterine horn and the uterine body of oestrous mares for four minutes before and four minutes after either coitus, or the artificial insemination of either 80.0 ml of fresh semen or 10.0 ml of fresh semen. The direction of the uterine contractions in each uterine horn and the uterine body was measured before and after coitus. Coitus and the inseminat...
Hogan PM, Embertson RM, Hunt RJ.A 4-month-old Thoroughbred foal was examined because of a history of exercise intolerance and lack of airflow from the right nostril since birth. Endoscopy of the airways revealed complete membranous obstruction of the right nasal passage at the level of the nasopharynx and marked narrowing of the caudal aspect of the right ventral meatus. Unilateral choanal atresia was diagnosed. Laser ablation of the obstructing tissues was attempted through a videoendoscope. Scar tissue occluded the right nasal passage at follow-up examination 7 weeks later. Intranasal resection, using laparoscopic instrume...
Wenzinger B, Kähn W, Bleul U.The aim of this study was to investigate the effect of a GnRH vaccine (Equity) on behavior and gonadal function in horses with unwanted behavior. The reason for the treatment was asked using a questionnaire and the findings of physical examination, rectal palpation as well as rectal ultrasonography, were recorded. The results of these examinations and the behavior of 21 mares and 10 stallions before the first and after the second administration of the GnRH vaccine were compared. In 84 % of all cases a decrease of the unwanted behavior could be observed. In the mares the ovaries were significan...
Hinchcliff KW, McKeever KH, Muir WW, Sams RA.The effect of premedication with phenylbutazone on systemic hemodynamic and diuretic effects of furosemide was examined in 6 healthy, conscious, mares. Mares were instrumented for measurement of systemic hemodynamics, including cardiac output and pulmonary arterial, systemic arterial, and intracardiac pressures, and urine flow. Each of 3 treatments was administered in a randomized, blinded study; furosemide (1 mg/kg of body weight, IV) only, phenylbutazone (8.8 mg/kg, PO, at 24 hours and 4.4 mg/kg, IV, 30 minutes before furosemide) and furosemide, or 0.9% NaCl. Phenylbutazone administration si...
McClure SR, Watkins JP, Ashman RB.Breaking strength (torque at failure) of equine third metacarpal bones, with transfixation pins placed parallel in the frontal plane and 30 degrees divergent from the frontal plane, was determined in vitro. Two transfixation pins were placed through the distal metaphysis, using a jig designed to drill the holes in the assigned configuration. Paired metacarpal bones II through IV from 12 horses were tested in torsion. The torsional moment of the force applied through the transfixation pins at failure was compared for each limb. Metacarpal bones with divergent pins were significantly (P = 0.030)...
Knight DA, Tyznik WJ.Fourteen Quarter Horse foals were used to evaluate the effects of artificial rearing on growth. Seven foals were removed from their dams at 3 d of age and fed a reconstituted 26% crude protein (CP) milk replacer free choice for 1 mo, at which time ad libitum solid feeding began. Controls were weaned from their dams at 2 mo of age and fed a 21% CP concentrate ad libitum until the end of the trial. Variables measured during the 26-wk trial were live body weight, height at the withers and length of body from point of shoulder to point of hip. No significant differences were found between the two ...
Cao XZ, Lin YZ, Li L, Jiang CG, Zhao LP, Lv XL, Zhou JH.The threshold hypothesis of attenuated lentiviral vaccine considers that the type of host response to infections of lentiviruses depends on the viral load. To evaluate the correlation between viral loads of the attenuated vaccine strain of equine infectious anemia virus (EIAV) and their effects to induce protective immunity, longitudinal plasma viral loads in groups of horses inoculated with either an attenuated EIAV vaccine strain (EIAV(DLV125)) or sub-lethal dose of an EIAV virulent strain (EIAV(LN40)) were compared. Similar levels of plasma viral loads ranging from 10(3)-10(5) copies/mL wer...
Brock BA, Greer HR, Honnas CM, Gilleland BE, Barrett MF, Moore JN, Cohen ND.Podotrochlear syndrome is a common cause of lameness in Quarter Horses involving both soft tissue and bony structures within the heel region. Current surgical treatment of podotrochlear syndrome addresses pathological changes affecting the soft tissue structures of the navicular region but does not address either edema or cyst-like lesions of the navicular bone. Unassigned: The objective of this randomized, self-controlled case series was to determine whether core osteostixis improved lameness in Quarter Horses with podotrochlear syndrome characterized by bilateral magnetic resonance imaging (...
Vörös K, Felkai C, Szilágyi Z, Papp A.Two-dimensional echocardiographic (2DE) examination was performed on a horse with clinical signs of pericardial effusion. Thickening of the pericardium, excess amount of pericardial fluid, elevation of the cardiac apex, and right ventricular compression, characteristic of cardiac tamponade, could be seen on 2DE recordings. Fibrinous pericarditis was suspected by observation of fibrinous strands in the pericardial fluid and epicardial fibrin deposits. Echocardiographically guided pericardiocentesis was performed, and 4 L of fluid was removed from the pericardial sac. Streptococcus zooepidemicus...
Borgsteede FH, van Beek G.The prevalence of tapeworm infestations was investigated in 70 horses slaughtered in the period February 1994-July 1994. Most horses were half-breed, young (1.5-3 years), and in good condition. They were bought for slaughter by dealers on local markets, and their treatment history was therefore unknown. Tapeworm infestations were seen in 16 horses (23%). Fifteen (21%) had an infection with Anoplocephala perfoliata. One horse had a single specimen of Paranoplocephala mamillana. The average number of A. perfoliata was 45 and the highest number was 508.
Wagner B, Siebenkotten G, Leibold W, Radbruch A.Due to characteristic clinical signs, immunoglobulins of isotype E (IgE) are believed to be involved in several allergic diseases of the horse. To date, closer investigations have been hampered by the fact that neither purified equine IgE nor anti-equine IgE monoclonal antibodies were available for IgE isotype determination. As an approach to solve this problem, we constructed a stable cell line (EqE6) that expresses recombinant equi-murine IgE specific for 4-(hydroxy-3-nitro-phenyl) acetyl (NP). Biochemical analysis of the purified protein revealed a highly glycosilated IgE monomer of approxi...
Recio P, Prieto D, Martínez MP, García P, Rivera L, Benedito S, Martínez AC, Sacristán AG, Orensanz LM, Hernández M.Our aim was to study the presence of noradrenergic nerves and to characterize the alpha-adrenergic receptors involved in the contractions to electrical field stimulation and to alpha-adrenergic agonists of the horse penile deep dorsal vein. Noradrenergic fibres were visualized by immunohistochemistry using an antibody against dopamine-beta-hydroxylase (DBH). For functional studies, the responses of the venous rings to electrical field stimulation and to alpha-adrenergic agonists (noradrenaline, phenylephrine and BHT 920) were studied in the absence and the presence of noradrenergic transmissio...
Hill FW, Knottenbelt DC, van Laeren K.One month after falling heavily a four-year-old horse developed acute colic while being exercised. A tentative diagnosis of diaphragmatic hernia was reached on the basis of the clinical findings and confirmed at laparotomy. The defect was repaired and the horse made an uneventful recovery.
Horohov DW, Loynachan AT, Page AE, Hughes K, Timoney JF, Fettinger M, Hatch T, Spaulding JG, McMichael J.Rhodococcus equi is a soil borne bacterium that causes severe morbidity and death in young foals. The economic costs of the disease include loss of life, treatment expenses, veterinary monitoring expenses and, perhaps most importantly, potential reduction in future athletic performance in horses that suffer severe lung abscessations caused by R. equi. Current standard of care for pneumonia caused by R. equi is treatment with a macrolide antimicrobial and rifampicin. However, the hallmark of pneumonia caused by R. equi is severe formation of pyogranulomas and a walling off effect that can preve...
Maede Y, Inaba M, Amano Y, Murase T, Goto I, Itakura C.Cryoglobulin was isolated from a horse which had glomerulo-nephritis and a history of swelling and skin ulcers of the limbs in the winter. The isolated cryoglobulin showed a single peak on a gel permeation chromatography column with an apparent molecular mass (Mr) of 180,000 which could be divided into two gamma bands by cellulose acetate electrophoresis. Immunoelectrophoretic analysis revealed that the cryoglobulin formed two precipitation lines with anti-horse IgG. Spur formation was observed when the cryoglobulin and the IgG purified from a normal healthy horse were cross-reacted with anti-...
Bertone AL, Cockerell GL, Lee RE, Stashak TS.Light microscopy, morphometry and scanning electron microscopy (SEM) were used to examine the mucosal morphology of seven intestinal specimens (three from the small intestine and four from the large intestine) from two horses not subjected to surgery and three horses one year after sham-operation for colon resection. Qualitative and quantitative evaluation revealed similar morphology for all horses except that the unoperated horses had significantly (P < 0.05) fewer goblet cells in the crypts of the large intestine. In the small intestine, SEM demonstrated that villus shape varied and range...
Iametti BS, Tedeschi G, Oungre E, Bonomi F.In this work the purification and the complete primary structure of kappa-casein from equine milk are reported for the first time. Mares' milk casein was separated by RP-HPLC into four fractions. Complete primary sequence was obtained by sequence analysis of the protein in the fastest eluting peak isolated by chromatography. This sequence was 95% identical to that reported for the C-terminal portion of the zebras' kappa-casein and showed high similarity with kappa-caseins from sources other than Equidae, confirming that this protein was indeed kappa-casein in equine milk. The presence of post-...
Steiss JE, Forsyth G.The effect of needle electromyography (EMG) on serum creatine kinase (CK) activity was determined, using clinically normal dogs (males and females; n = 8) and horses (females; n = 8). All animals appeared normal on EMG evaluation. Serum CK was measured before and 4, 24, and 48 hours after EMG. Except for a single 24-hour sample in a dog, the animals did not have abnormally increased serum CK activity after EMG. For dogs and horses, mean values were increased, but within normal range at 4 and 24 hours and returned to base-line values by 48 hours after EMG. For dogs, but not for horses, these CK...