Omneity® Pellets
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Topic:Horses
"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Oxygen radical production by horse and pig neutrophils induced by a range of crystals. The exposure of animal neutrophils to crystals implicated in joint inflammation induces superoxide and peroxide generation in a concentration and temperature dependent fashion. Active crystals were urate, hydroxyapatite, pyrophosphate and brushite; diamond and cholesterol were inactive. Cytochalasin B increased superoxide yield after addition of brushite, and inhibitors of the PMA induced respiratory burst blocked the crystal induced response. Addition of urate to anaerobic neutrophils causes the reduction of a b-type cytochrome, a likely component of the neutrophil superoxide generating syste...
Independence of exercise hypocapnia and limb movement frequency in ponies. The objective of this study was to determine whether changes in limb motion per se influence arterial CO2 partial pressure (PaCO2) during muscular exercise in ponies. Fifteen ponies were studied at rest and during 8 min of treadmill exercise when the work load was constant or when the work load was increased after the 4th min. Five different treadmill settings were selected to provide for a range of metabolic rate achieved with primary changes in either speed or grade (1.8 mph at 3, 8, and 15% grade; or 3 and 6 mph at 3% grade). The ponies exercised either on all four legs or on only the hindl...
Population distributions of phenylbutazone and oxyphenbutazone after oral and i.v. dosing in horses. Experiments to determine the residual plasma concentrations of phenylbutazone and its metabolites found in horses racing on a 'no-race day medication' or 24-h rule were carried out. One dosing schedule (oral-i.v.) consisted of 8.8 mg/kg (4 g/1000 lbs) orally for 3 days, followed by 4.4 mg/kg (2 g/1000 lbs) intravenously on day 4. A second schedule consisted of 4.4 mg/kg i.v. for 4 days. The experiments were carried out in Thoroughbred and Standardbred horses at pasture, half-bred horses at pasture, and in Thoroughbred horses in training. After administering the i.v. schedule for 4 days to Thor...
The primary structure of monomeric beta-lactoglobulin I from horse colostrum (Equus caballus, Perissodactyla). beta-Lactoglobulin-like proteins were detected in horse colostrum and normal milk using immunological techniques. In contrast to the beta-lactoglobulins sequenced so far these proteins are monomeric and genetically not homogenous. In this paper we report the first primary structure of a monomeric beta-lactoglobulin from horse colostrum. By means of an automatic liquid-phase sequenator the sequence of peptides obtained by tryptic digestion and by cyanogen bromide cleavage was determined. A limited tryptic digestion and hydrolysis with chymotrypsin provided the necessary overlapping peptides. Th...
An investigation of the effect of hesperidin complex and lemon bioflavonoid complex on growth and development of thoroughbred horses. The objective of this study was to determine the effect of Hesperidin Complex and Lemon Bioflavonoid Complex (HC/LBC) on the growth and development of thoroughbred horses. The trial involved twenty-four foals (12 colts, 12 fillies) allotted to treatment shortly after weaning. The study was conducted for a 342-d growing phase and a 153-d training phase, or a total of 495-d. The HC/LBC was included in the test diet at a level calculated to supply the compound at 55 mg X kg body weight-1 X d-1. During the growing phase, average daily gain of colts that received HC/LBC was higher (P less than .05)...
Experimental infection of mares with Haemophilus equigenitalis. Inoculation of Haemophilus equigenitalis into the uterus of 7 mares caused a disease clinically indistinguishable from contagious equine metritis. The duration of clinical signs varied from 4 to 11 days. The causative organism persisted for a relatively short time (2 to 10 weeks) in 5 mares, but in 2 others it established a carrier status and persisted until they were killed 6 and 10 months after infection. H. equigenitalis was recovered from the vestibule of the vagina and from a combined swab of the clitoral fossa and sinuses throughout the course of the infection. In some mares there were e...
Pharmacokinetics and bioavailability of theophylline in horses. The pharmacokinetics and bioavailability of theophylline in horses were investigated following both intravenous and intragastric administration of aminophylline solutions at doses corresponding to 15 and 10 mg/kg theophylline base. A rapid distributive phase with a half-life of approximately 15-30 min was followed by a slower elimination half-life averaging 15-17 h. The apparent volume of distribution averaged 850-900 ml/kg. Theophylline, administered as aminophylline solution, was both rapidly and completely absorbed from the equine digestive tract. Based on the bioavailability and dispositio...
Cadmium/zinc relationships in kidney cortex and metallothionein of horse and red deer: histopathological observations on horse kidneys. Cadmium and zinc were determined in kidney cortex of 63 horses and 51 red deer (Cervus elaphus). Cadmium and zinc were also determined in protein fractions obtained by Sephadex chromatography of kidney cortex from 10 horses and 4 red deer. Histopathological parameters in kidney cortex of horses were compared to cadmium content. The metal contents (on wet weight basis) in kidney cortex of the horses were 0.31 +/- 0.22 mmole Cd/kg (range 0.03-1.21) and 0.63 +/- 0.17 mmole Zn/kg (range 0.36-1.23). The Zn content increased with the Cd content, the Zn increase being less at higher concentrations. N...
Isolation of Streptococcus pneumoniae type 3 from equine species. Streptococcus pneumoniae type 3 was isolated from seven tracheobronchial aspirates and one pleural tap of seven adult horses and one foal. There was no direct evidence in these horses that isolation of the pneumococcus was related to a specific disease syndrome. Presenting complaints included two horses with chronic cough, two horses with decreased exercise tolerance, one horse with exercise-induced pulmonary hemorrhage, and three horses with pneumonia. Antibiotic therapy resolved the primary clinical complaint. This is the first report of the isolation of S. pneumoniae type 3 from adult horse...
Specificity of pseudorabies virus serotests. Pigs experimentally inoculated with bovine herpesvirus-1 or equine herpesvirus-1 developed mild clinical disease signs. Regression of clinical disease was accompanied by development of specific virus-neutralizing antibodies. These antibodies did not react positively with pseudorabies antigens in the serum-virus neutralization test, an indirect radioimmunoassay, or a microimmunodiffusion test.
Nutritionally variant streptococci from corneal ulcers in horses. Of 24 isolates of nutritionally variant streptococci recovered from equine corneal ulcers, 22 were tested for growth requirements, physiological and biochemical reactions, and susceptibility to different antimicrobial agents. Satisfactory growth was obtained by supplementing blood agar and Todd-Hewitt broth with pyridoxal hydrochloride, and all of the media for the culture and the biochemical testing were supplemented with 0.002% of this substance. Biochemical patterns of 12 of the isolates resembled those of two viridans streptococcal species, Streptococcus intermedius and Streptococcus const...
Spavin: a proposed term for a non-fracture associated canine hock lesion. In accordance with macroscopic and microscopic features of the tarsal joint degeneration in the greyhound dog, the possibility of establishing a direct relation between this process and spavin or bone spavin is proposed. To date this has been considered limited to equine and occasionally bovine stock. This investigation has been carried out on three different levels: macroscopic, radiological and histological and has been completed with the corresponding graphic documentation.
“The grave yawns for the horseman.” Equestrian deaths in South Australia 1973-1983. The fatalities associated with the riding and handling of horses in South Australia over the 11-year period 1973-1983 are reviewed. There were 18 deaths, including two sudden natural deaths in the saddle and one drowning. The 15 cases of horse-related trauma represent a death rate of approximately one per million population per annum. Thirteen of the deaths were the result of a head injury after a fall. Nine persons were not wearing protective headgear. The two principal groups at risk were male professional riders with a mean age of 32 years and female amateurs with a mean age of 19 years.
Rapid screening and confirmation for drugs and metabolites in racing animals by tandem mass spectrometry. A screening and confirmation procedure for drugs and metabolites in the blood serum and urine of racing animals was developed. Equine blood serum was spiked with low concentrations of several drugs of interest. Canine blood serum and urine were collected following oral doses of diethylcarbamazine, procaine, and phenylbutazone. Serum, urine, and extracts of each were analyzed, using a triple quadrupole mass spectrometer. Simultaneous screening of up to 50 drugs was possible in a single sample, in less than 2 minutes. Detection limits for most compounds were in the ng/ml to microgram/ml range, u...
Equine cell-mediated immune response to Rhodococcus (Corynebacterium) equi. A lymphocyte blastogenic assay was developed to serve as an in vitro correlate of cell-mediated immunity to Rhodococcus (Corynebacterium) equi (R equi) in the equine species. Lymphocytes obtained from a group of experimental ponies showed no response in cell culture to R equi heat extract or lysozyme extract antigens. Ponies were assigned to groups for experimental inoculation. Three ponies were inoculated subcutaneously with live R equi, 3 were given live R equi by intranasal and intratracheal routes, and 4 ponies were left untreated. Lymphocytes from all inoculated ponies had a mitogenic res...
Importance of uniform cuff application for equine blood pressure measurement. Seventeen horses were used to determine the variances associated with blood pressure cuff application (Sp2) and with other inherent errors (So2). Systolic pressure values had Sp2 = 3.9 mmHg and So2 = 5.6 mmHg, while diastolic pressure values had Sp2 = 1.1 mmHg and So2 = 4.4 mmHg. Thus, to be considered different, two blood pressure means (in mmHg), each derived from three readings, had to differ by at least 3.9 for systolic pressure and 3.4 for diastolic pressure when all readings were made without cuff displacement; 6.8 for systolic pressure and 4.6 for diastolic pressure when the cuff was re...
