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Topic:Laryngeal Dysfunction

Laryngeal dysfunction in horses refers to a range of conditions affecting the larynx, which is a critical structure involved in breathing and vocalization. These conditions can impact the horse's performance and respiratory efficiency. Common types of laryngeal dysfunction include recurrent laryngeal neuropathy (RLN), arytenoid chondritis, and laryngeal hemiplegia. These disorders may result in abnormal respiratory noises and exercise intolerance. Diagnosis typically involves endoscopic examination to assess the structure and function of the larynx. This page compiles peer-reviewed research studies and scholarly articles that explore the etiology, diagnosis, and management of laryngeal dysfunction in horses.
Endoscopic observations on laryngeal symmetry and movements in young racing horses.
New Zealand veterinary journal    July 21, 2005   Volume 45, Issue 5 188-192 doi: 10.1080/00480169.1997.36024
Anderson BH, Kannegieter NJ, Goulden BE.An endoscopic survey of young race horses was performed to examine the prevalence and character of laryngeal movements during quiet respiration. The main aim was to determine whether those arytenoid movements which could possibly reflect the efficiency of left dorsal cricoarytenoid muscle function changed over a period of time. Of the 452 horses examined, 439 were Thoroughbreds and 23 were Standardbreds, 250 were less than 2 years of age (6-21 months), and 202 were 2 years old. One hundred and nine of these horses were examined again 16 months later. Arytenoid movements were given one of four ...
Thoracolaryngeal reflex latencies in Thoroughbred horses with recurrent laryngeal neuropathy.
Veterinary journal (London, England : 1997)    July 5, 2005   Volume 170, Issue 1 67-76 doi: 10.1016/j.tvjl.2004.03.020
Curtis RA, Hahn CN, Evans DL, Williams T, Begg L.Electrolaryngeography was used to study the latencies of the thoracolaryngeal adductor reflex in Thoroughbred horses with and without recurrent laryngeal neuropathy (RLN). Latencies were compared in horses with grades 1 and 2 RLN, diagnosed by endoscopy in resting horses. The reliability of the measurements, effect of sedation and correlations of latencies with age of the horse were also studied. There was no effect of sedation on reflex latency periods. The latency of the reflex period measured to a convolved peak of the electromyographic response was significantly different in horses with gr...
Diagnosis of dorsal displacement of the soft palate by sound spectrum analysis; the way ahead?
Equine veterinary journal    December 8, 2004   Volume 36, Issue 7 554-555 doi: 10.2746/0425164044864499
Dixon PM, Holcombe SJ.No abstract available
The displaced equine soft palate as a source of abnormal respiratory noise during expiration.
Equine veterinary journal    December 8, 2004   Volume 36, Issue 7 590-594 doi: 10.2746/0425164044864453
Franklin SH, Price C, Burn JF.To develop the technique of respiratory sound analysis for the diagnosis of dorsal displacement of the equine soft palate. Objective: To show that 1) the displaced soft palate can spontaneously vibrate in the presence of expiratory airflow; 2) the observed frequency of vibration can be detected in respiratory sound recordings; and 3) the frequency of vibrations measured in cadaveric specimens are similar to those obtained from audio spectra in exercising horses with DDSP. Methods: Palatal movements and respiratory sounds were recorded from artificially ventilated cadaveric heads. The fundament...
High-speed treadmill videoendoscopic examination of the upper respiratory tract in the horse: the results of 291 clinical cases.
Veterinary journal (London, England : 1997)    September 25, 2004   Volume 170, Issue 2 243-248 doi: 10.1016/j.tvjl.2004.06.011
Tan RH, Dowling BA, Dart AJ.The purpose of the study was to describe the prevalence of upper airway abnormalities and establish if any significant associations existed between study variables and the two most frequently identified disorders; axial deviation of the aryepiglottic folds and dorsal displacement of the soft palate. The clinical records and video-recordings of all horses referred for upper respiratory tract evaluation during high-speed treadmill videoendoscopy between November 1997 and September 2003 were reviewed. Of 291 horses included in the study, 265 underwent resting endoscopy and 42% (112/265) had a rec...
Effect of laryngoplasty on respiratory noise reduction in horses with laryngeal hemiplegia.
Equine veterinary journal    July 16, 2004   Volume 36, Issue 5 420-425 doi: 10.2746/0425164044868440
Brown JA, Derksen FJ, Stick JA, Hartmann WM, Robinson NE.Laryngoplasty is the technique of choice for treatment of laryngeal hemiplegia, with the aim of improving airway function and/or eliminating respiratory noise. However, there are no quantitative data in the literature describing the effect of laryngoplasty on upper airway noise or its relationship to upper airway mechanics in horses with laryngeal hemiplegia. Objective: To determine whether laryngoplasty reduces respiratory noise in exercising horses with laryngeal hemiplegia; and to establish whether the degree of upper airway obstruction can be predicted by upper airway noise, or the degree ...
Performance after partial arytenoidectomy without mucosal closure in 27 Thoroughbred racehorses.
Veterinary surgery : VS    July 3, 2004   Volume 33, Issue 4 398-403 doi: 10.1111/j.1532-950X.2004.04058.x
Barnes AJ, Slone DE, Lynch TM.To examine the effect of partial arytenoidectomy without mucosal closure on postoperative racing performance and long-term complications in Thoroughbred racehorses treated for laryngeal hemiplegia, arytenoid chondropathy, or failed laryngoplasty. Methods: Retrospective study. Methods: Twenty-seven Thoroughbred racehorses. Methods: Medical records of Thoroughbred racehorses that had partial arytenoidectomy without mucosal closure between 1992 and 2002 were reviewed. Horses were divided into groups: horses that had not raced (Group 1) and those that had raced (Group 2) before surgery. Lifetime r...
Effects of stylopharyngeus muscle dysfunction on the nasopharynx in exercising horses.
Equine veterinary journal    May 28, 2004   Volume 36, Issue 4 318-323 doi: 10.2746/0425164044890553
Tessier C, Holcombe SJ, Derksen FJ, Berney C, Boruta D.Nasopharyngeal collapse has been observed in horses as a potential cause of exercise intolerance and upper respiratory noise. No treatment is currently available and affected horses are often retired from performance. Objective: To determine the effect of bilateral glossopharyngeal nerve block and stylopharyngeus muscle dysfunction on nasopharyngeal function and airway pressures in exercising horses. Methods: Endoscopic examinations were performed on horses at rest and while running on a treadmill at speeds corresponding to HRmax50, HRmax75 and HRmax, with upper airway pressures measured with ...
Assessment of the efficacy of composite surgery for the treatment of dorsal displacement of the soft palate in a group of 53 racing Thoroughbreds (1990-1996).
Equine veterinary journal    March 25, 2004   Volume 36, Issue 2 175-179 doi: 10.2746/0425164044868701
Barakzai SZ, Johnson VS, Baird DH, Bladon B, Lane JG.There has been no objectively assessed case-control study of the efficacy of surgery to correct dorsal displacement of the soft palate (DDSP) previously reported. Objective: Composite surgery has a beneficial result on racing performance in horses affected with DDSP as compared to a matched control population. Methods: Race records were obtained for 53 racing Thoroughbreds which underwent composite staphylectomy, sternothyrohyoideus myectomy and ventriculectomy for correction of idiopathic DDSP at the University of Bristol between 1990 and 1996. Each surgical case was matched for age, sex and ...
Laryngoplasty with ventriculectomy or ventriculocordectomy in 104 draft horses (1992-2000).
Veterinary surgery : VS    December 3, 2003   Volume 32, Issue 6 530-538 doi: 10.1111/j.1532-950x.2003.00530.x
Kraus BM, Parente EJ, Tulleners EP.To evaluate efficacy and safety of laryngoplasty with vetriculectomy (VE) or ventriculocordectomy (VCE) for treatment of laryngeal hemiplegia (LH) in draft horses. Methods: Retrospective study. Methods: One hundred four draft horses used for competitive hitch competitions. Methods: Medical records and postoperative endoscopy for competitive hitch draft horses diagnosed with left LH and treated with laryngoplasty and VE or VCE between January 1992 and December 2000 were reviewed. Follow-up information was obtained from telephone interviews with owners and trainers, and performance scores of 1 t...
Ventriculocordectomy reduces respiratory noise in horses with laryngeal hemiplegia.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 570-574 doi: 10.2746/042516403775467135
Brown JA, Derksen FJ, Stick JA, Hartmann WM, Robinson NE.Show and performance horse with laryngeal hemiplegia (LH) often present for excessive respiratory noise rather than significant exercise intolerance. Therefore, the goal of surgery in these horses is to reduce respiratory noise but there are no quantitative studies evaluating the effect of any upper-airway surgery in LH-affected horses. Objective: To determine whether bilateral ventriculocordectomy (VC) reduces respiratory noise in exercising horses with laryngeal hemiplegia. Methods: Six Standardbred horses with normal upper airways were used in this study. Respiratory sounds and inspiratory ...
Long-term survey of laryngoplasty and ventriculocordectomy in an older, mixed-breed population of 200 horses. Part 1: Maintenance of surgical arytenoid abduction and complications of surgery.
Equine veterinary journal    July 26, 2003   Volume 35, Issue 4 389-396 doi: 10.2746/042516403776014172
Dixon RM, McGorum BC, Railton DI, Hawe C, Tremaine WH, Dacre K, McCann J.Laryngoplasty (LP) is currently the most common surgical treatment for equine laryngeal paralysis, however, there have been no reports quantifying the degree of retention of arytenoid abduction following LP. Additionally, the complications of LP have been poorly documented. Objective: To record the degree of arytenoid abduction retention following LP and to accurately document all complications of surgery. Methods: A study (1986-1998) of 200 horses of mixed breed and workload, median age 6 years (prospective 136 cases and retrospective 64 cases) undergoing LP (using 2 stainless steel wires) an...
Long-term survey of laryngoplasty and ventriculocordectomy in an older, mixed-breed population of 200 horses. Part 2: Owners’ assessment of the value of surgery.
Equine veterinary journal    July 26, 2003   Volume 35, Issue 4 397-401 doi: 10.2746/042516403776014217
Dixon PM, McGorum BC, Railton DI, Hawe C, Tremaine WH, Dacre K, McCann J.There is continuing debate on the clinical benefit of laryngoplasty (LP) in the treatment of equine laryngeal paralysis. In particular, there is little information available on the clinical value of this surgery in older horses, in non-Thoroughbreds or in sports or pleasure horses; nor on the relationship between the degree of LP abduction achieved and the clinical value of LP. Objective: To evaluate the owner's assessment of the value of LP (and combined ventriculocordectomy) in an older, mixed breed and mixed workload population of horses and to also assess the relationship between the degre...
Spectral analysis of respiratory noise in horses with upper airway disorders.
Equine veterinary journal    May 21, 2003   Volume 35, Issue 3 264-268 doi: 10.2746/042516403776148228
Franklin SH, Usmar SG, Lane JG, Shuttleworth J, Burn JF.It has long been recognised that the production of abnormal respiratory sounds by horses during exercise is frequently associated with upper airway obstructions. Respiratory acoustic measurements have shown promise in investigation of upper airway disorders in man and, more recently, in horses with experimentally-induced obstructions. Objective: To evaluate sounds from exercising horses with naturally occurring dynamic obstructions of the upper respiratory tract and to compare these with those from normal horses in order to determine whether different obstructions produce characteristic spectr...
Laryngeal reinnervation in the horse.
The Veterinary clinics of North America. Equine practice    May 16, 2003   Volume 19, Issue 1 189-viii doi: 10.1016/s0749-0739(02)00073-1
Fulton IC, Stick JA, Derksen FJ.Left laryngeal hemiplegia is a frustrating condition for the equine athlete and equine veterinarian. Treatment for the past 30 years has centered on the prosthetic laryngoplasty ("tie-back") with or without ventriculectomy. Laryngeal reinnervation has been used successfully in people and has been shown experimentally to benefit affected horses. This article reviews equine laryngeal reinnervation using the nerve muscle pedicle graft and describes the surgical technique, its complications, and the follow-up in 146 cases treated over the past 10 years. Also discussed is ongoing research into stim...
Unilateral thyroidectomy in 6 horses.
Veterinary surgery : VS    April 15, 2003   Volume 32, Issue 2 187-190 doi: 10.1053/jvet.2003.50017
Elce YA, Ross MW, Davidson EJ, Tulleners EP.To describe the surgical technique, complications, and outcome of thyroidectomy in 6 horses. Methods: Retrospective study. Methods: Six horses, 10 to 22 years of age, with unilateral, rapidly enlarging thyroid masses. Methods: Medical records between 1985 and 2000 were reviewed for horses that had unilateral thyroidectomy. Retrieved data included signalment, physical, clinical, and ultrasonographic examination findings, surgical technique, complications, and outcome. A minimum of 6 months follow-up was obtained. Results: Six horses were identified. Three horses had tracheal compression and 2 o...
Sound signature for identification and quantification of upper airway disease in horses.
American journal of veterinary research    December 21, 2002   Volume 63, Issue 12 1707-1713 doi: 10.2460/ajvr.2002.63.1707
Cable CS, Ducharme NG, Hackett RP, Erb HN, Mitchell LM, Soderholm LV.To investigate whether upper airway sounds of horses exercising with laryngeal hemiplegia and alar fold paralysis have distinct sound characteristics, compared with unaffected horses. Methods: 6 mature horses. Methods: Upper airway sounds were recorded in horses exercising on a high-speed treadmill at maximum heart rate (HR(MAX)) under 3 treatment conditions (ie, normal upper airway function [control condition], and after induction of left laryngeal hemiplegia or bilateral alar fold paralysis) in a randomized crossover design. Fundamental frequency, spectrograms using Gabor transform, and inte...
Dorsal displacement of the soft palate in 92 horses during high-speed treadmill examination (1993-1998).
Veterinary surgery : VS    November 5, 2002   Volume 31, Issue 6 507-512 doi: 10.1053/jvet.2002.36009
Parente EJ, Martin BB, Tulleners EP, Ross MW.To evaluate the occurrence of dorsal displacement of the soft palate (DDSP) during high-speed treadmill (HSTM) exercise in racehorses, and determine treatment efficacy relative to the endoscopic findings observed during resting and HSTM endoscopic examination. Methods: Retrospective study. Animals-Ninety-two racehorses (74 Thoroughbreds, 18 Standardbreds). Methods: The signalment, history (clinical and race), treatments, and video recordings made during resting and HSTM endoscopy were reviewed in 92 racehorses that developed DDSP during HSTM exercise. Only horses that completed 3 starts before...
Effect of dorsal displacement of the soft palate on ventilation and airflow during high-intensity exercise.
Equine veterinary journal. Supplement    October 31, 2002   Issue 34 379-383 doi: 10.1111/j.2042-3306.2002.tb05452.x
Franklin SH, Naylor JR, Lane JG.Dorsal displacement of the soft palate (DDSP) is one of the most common obstructive conditions of the upper respiratory tract in the racehorse. The present study was conducted to determine the effects of intermittent dorsal displacement of the soft palate (DDSP) on ventilation and respiratory airflow during high intensity exercise. Videoendoscopic recordings were made of the nasopharynx and larynx simultaneously with measurements of airflow and respiratory gas exchange, during high-speed treadmill exercise in 9 horses with confirmed intermittent DDSP admitted for clinical investigation of poor...
Xylazine-induced attenuation of dorsal displacement of the soft palate associated with epiglottic dysfunction in a horse.
Journal of the American Veterinary Medical Association    August 8, 2002   Volume 221, Issue 3 399-368 doi: 10.2460/javma.2002.221.399
Duggan VE, MacAllister CG, Davis MS.An 18-month-old Quarter Horse filly was evaluated because of dorsal displacement of the soft palate associated with epiglottic dysfunction that caused exercise intolerance and an abnormal respiratory noise. The abnormality of the epiglottis was corrected by use of a sedative dose of xylazine hydrochloride. There was no familial predisposition to hyperkalemic periodic paralysis, which may cause similar laryngopharyngeal signs, and the horse did not respond to administration of acetazolamide. There was no known history of trauma that could have caused neuritis, which has also been suggested as a...
Treatment of laryngeal hemiplegia in horses by prosthetic laryngoplasty, ventriculectomy and vocal cordectomy.
The Veterinary record    May 9, 2002   Volume 150, Issue 15 481-484 doi: 10.1136/vr.150.15.481
Kidd JA, Slone DE.The medical records of 80 horses treated for left laryngeal hemiplegia by prosthetic laryngoplasty, ventriculectomy and vocal cordectomy were examined, first to compare the subjective and objective success rates for groups of horses of different ages and used for different purposes, and secondly, to compare the efficacy of including vocal cordectomy in the surgical protocol with published success rates for laryngoplasty and ventriculectomy alone. Subjectively, 70 per cent of the horses were said to have had a successful surgical outcome. The success rate for thoroughbred racehorses (66 per cen...
Clinical and endoscopic evidence of progression in 152 cases of equine recurrent laryngeal neuropathy (RLN).
Equine veterinary journal    January 31, 2002   Volume 34, Issue 1 29-34 doi: 10.2746/042516402776181169
Dixon PM, McGorum BC, Railton DI, Hawe C, Tremaine WH, Pickles K, McCann J.Examination of the long-term histories and clinical findings was performed in 351 horses suffering from recurrent laryngeal neuropathy (RLN) to examine for possible evidence of progression of this disorder. Fifty-two out of 351 cases (15%) had evidence of progression of the degree of laryngeal dysfunction over a median period of 12 months (range 1.5-48 months) with the onset of progression occurring at median age 7 years. In 30 cases, there was both endoscopic (median deterioration of 3 endoscopic grades; range 1-5 grades) and clinical evidence, with 29 (97%) of these horses concurrently devel...
The equine larynx.
New Zealand veterinary journal    January 1, 2002   Volume 50, Issue sup3 117 doi: 10.1080/00480169.2002.36286
Goulden B.Abstract Extract A series of landmark studies on the function of the equine larynx was conducted by a group of researchers at Massey University between 1970 and 1987. These studies commenced with investigations on the normal laryngeal anatomy and physiology (Goulden et al 1976a; Anderson et al 1980; Quinlan et al 1982), and progressed to a clinical appraisal of laryngeal hemiplegia, the most important clinical disease affecting the horse's larynx (Goulden and Anderson 198 lab, 1982). The studies concluded with a series of in-depth cytological and pathological studies of the intrinsic laryngeal...
Endoscopic assessment of airway function as a predictor of racing performance in Thoroughbred yearlings: 427 cases (1997-2000).
Journal of the American Veterinary Medical Association    October 17, 2001   Volume 219, Issue 7 962-967 doi: 10.2460/javma.2001.219.962
Stick JA, Peloso JG, Morehead JP, Lloyd J, Eberhart S, Padungtod P, Derksen FJ.To compare endoscopic findings of the upper portion of the respiratory tract in Thoroughbred yearlings with their subsequent race records to determine whether subjective assessment of airway function may be used as a predictor of future racing performance. Methods: Retrospective study. Methods: 427 Thoroughbred yearlings. Methods: Endoscopic examination findings were obtained from the medical records and the videoendoscopic repository of the Keeneland 1996 September yearling sales. Racing records were requested for the yearlings through the end of their 4-year-old racing season (1997-2000). Tw...
Laryngeal paralysis: a study of 375 cases in a mixed-breed population of horses.
Equine veterinary journal    September 18, 2001   Volume 33, Issue 5 452-458 doi: 10.2746/042516401776254790
Dixon PM, McGorum BC, Railton DI, Hawe C, Tremaine WH, Pickles K, McCann J.Referred cases (n = 375) of laryngeal paralysis (1985-1998) from a mixed-breed equine population included 351 (94%) cases of recurrent laryngeal neuropathy (RLN) (idiopathic laryngeal hemiplegia) and 24 cases (6%) of laryngeal paralysis from causes other than RLN. Laryngeal movements were classified endoscopically into one of 6 grades, in contrast to the usual 4 grades. The RLN cases had a median grade 4 laryngeal paralysis, of which 96% were left-sided, 2% right-sided and 2% bilaterally affected. RLN cases included 204 (58%) Thoroughbred, 96 (27%) Thoroughbred-cross, 23 (7%) draught, 16 (5%) ...
A study of an electrodiagnostic technique for the evaluation of equine recurrent laryngeal neuropathy.
Equine veterinary journal    September 18, 2001   Volume 33, Issue 5 459-465 doi: 10.2746/042516401776254826
Hawe C, Dixon PM, Mayhew IG.The electrodiagnostic measurement of the thoracolaryngeal reflex (TLR) ('slap test') latency was compared to 5 other diagnostic techniques used for evaluation of laryngeal function, namely laryngeal muscle palpation, resting and immediately postexercise endoscopic examinations, and palpable and endoscopic responses to the TLR. Compared to resting endoscopy, the electrodiagnostic measurement of TLR latency was not found to be an accurate test for the evaluation of recurrent laryngeal neuropathy (RLN), nor was laryngeal muscle palpation or the endoscopic response to the TLR. Twenty-five (71%) of...
The effect of recurrent laryngeal neurectomy in conjunction with laryngoplasty and unilateral ventriculocordectomy in thoroughbred racehorses.
Veterinary surgery : VS    September 14, 2001   Volume 30, Issue 5 417-421 doi: 10.1053/jvet.2001.25865
Davenport CL, Tulleners EP, Parente EJ.To investigate the effects of recurrent laryngeal neurectomy (RLN) in combination with laryngoplasty and ventriculocordectomy on the postoperative performance of Thoroughbred racehorses treated for grade III left laryngeal hemiparesis (LLH). Methods: Retrospective study. Methods: Fifty-five Thoroughbred racehorses. Methods: Medical records for Thoroughbred racehorses treated surgically by laryngoplasty and laser ventriculocordectomy with or without RLN between June 1993 and December 1996 were reviewed. Outcome was evaluated subjectively by assessment of performance obtained from telephone inte...
Spectrum analysis of respiratory sounds in exercising horses with experimentally induced laryngeal hemiplegia or dorsal displacement of the soft palate.
American journal of veterinary research    May 9, 2001   Volume 62, Issue 5 659-664 doi: 10.2460/ajvr.2001.62.659
Derksen FJ, Holcombe SJ, Hartmann W, Robinson NE, Stick JA.To record respiratory sounds in exercising horses and determine whether spectrum analysis could be use to identify sounds specific for laryngeal hemiplegia (LH) and dorsal displacement of the soft palate (DDSP). Methods: 5 Standardbred horses. Methods: Respiratory sounds were recorded and pharyngeal pressure and stride frequency were measured while horses exercised at speeds corresponding to maximum heart rate, before and after induction of LH and DDSP. Results: When airway function was normal, expiratory sounds predominated and lasted throughout exhalation. After induction of LH, expiratory s...
Evaluation of high-speed treadmill videoendoscopy for diagnosis of upper respiratory tract dysfunction in horses.
Australian veterinary journal    March 21, 2001   Volume 79, Issue 2 109-112 doi: 10.1111/j.1751-0813.2001.tb10713.x
Dart AJ, Dowling BA, Hodgson DR, Rose RJ.To evaluate high-speed treadmill videoendoscopy as a diagnostic technique and document the abnormalities found in Australian horses referred for poor performance associated with abnormal upper respiratory tract noise but where a definitive diagnosis could not be made at rest. Methods: A retrospective clinical study using client-owned horses. Methods: The clinical records and videorecordings of all horses referred to the University of Sydney for poor performance associated with abnormal upper respiratory tract noise during a 13-month period were examined. Only horses with a normal physical exam...
Transendoscopic laser treatment of rostral displacement of the palatopharyngeal arch in four horses.
Journal of clinical laser medicine & surgery    February 24, 2001   Volume 17, Issue 2 49-52 doi: 10.1089/clm.1999.17.49
Blikslager AT, Tate LP, Tudor R.To document the use and clinical outcome of transendoscopic laser techniques for treatment of rostral displacement of the palatopharyngeal arch (RDPA) in horses. Background: Rostral displacement of the palatopharyngeal arch is a rare cause of upper respiratory noise and exercise intolerance in horses, and may be associated with abnormal laryngeal anatomy. There are few reports of successful treatment of this condition, and no reports of the treatment of RDPA using laser techniques. Methods: The diagnosis of RDPA was based on the presence of palatal tissue covering the dorsal aspect of the aryt...
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