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Topic:Local Anaesthesia

Local anaesthesia in horses involves the administration of agents that temporarily block nerve conduction, resulting in a loss of sensation in a specific area of the body. This technique is employed in various veterinary procedures to facilitate pain management and allow for the performance of minor surgical interventions without the need for general anaesthesia. Common local anaesthetic agents used in equine medicine include lidocaine, mepivacaine, and bupivacaine. These agents are selected based on their duration of action and specific application requirements. The use of local anaesthesia can help minimize stress and recovery time for horses undergoing treatment. This page compiles peer-reviewed research studies and scholarly articles that explore the pharmacology, application methods, and clinical outcomes associated with local anaesthesia in equine practice.
Narcotics and local anesthetics.
The Veterinary clinics of North America. Equine practice    December 1, 1993   Volume 9, Issue 3 605-620 doi: 10.1016/s0749-0739(17)30388-7
Kamerling SG.The recognition and alleviation of animal pain is a growing veterinary and public concern. Pain can be of an acute or chronic nature with different behavioral manifestations. Physiologically, pain is a dynamic and complex phenomenon that produces changes in the central and autonomic nervous systems as well as in the endocrine system. Horses and other animals appear to possess an endogenous pain-suppressing system involving the brainstem and spinal cord. This system can modulate pain perception and the responses to it. The recently discovered endogenous opioid peptides (endorphins and enkephali...
A study of 118 cases of navicular disease: clinical features.
Equine veterinary journal    November 1, 1993   Volume 25, Issue 6 488-492 doi: 10.1111/j.2042-3306.1993.tb02999.x
Wright IM.The clinical features are reported from 118 horses (mean age 9.2 years) which were diagnosed as suffering from navicular disease using predetermined criteria. The animals were used for a variety of purposes and had been lame for periods between 1 and 72 months. The majority of cases (84.7%) had been treated using various techniques before evaluation. The severity of lameness was related to the duration of clinical signs: 78% of horses were bilaterally affected but there was no left:right limb predominance. Broken foot/pastern axes were recorded in 75% of horses while 45% also exhibited mediola...
An investigation of injection techniques for local analgesia of the equine distal tarsus and proximal metatarsus.
Equine veterinary journal    January 1, 1993   Volume 25, Issue 1 30-35 doi: 10.1111/j.2042-3306.1993.tb02897.x
Dyson SJ, Romero JM.A positive radiographic contrast agent was injected into the tarsometatarsal (TMT) joints of both hindlimbs of 10 horses. Lateromedial radiographic views were obtained at 5, 15 and 30 mins after injection. Injection was successful in 19 of 20 limbs. Communication between the centrodistal (CD) and TMT joints was identified in 7 limbs (35%). Contrast agent extended around the tendons of tibialis cranialis (TC) and fibularis tertius (FT) in 18 limbs, and in 7 limbs some contrast entered the tarsal sheath. Slight to moderate plantar and/or distal extension of contrast agent was identified in 13 li...
Septic arthritis in 15 standardbred racehorses after intra-articular injection.
Equine veterinary journal    November 1, 1992   Volume 24, Issue 6 430-434 doi: 10.1111/j.2042-3306.1992.tb02872.x
Lapointe JM, Laverty S, Lavoie JP.Case histories, results of synovial fluid analyses, treatment regimens and outcome are described for 15 adult Standardbred horses with confirmed post-injection septic arthritis. Joint sepsis followed injection of corticosteroids, hyaluronic acid, polysulphated glycosaminoglycan, or local anaesthetic. The median interval from injection to appearance of clinical signs was 2.5 days, and median interval from injection to referral was 9 days. The median initial synovial leucocyte count on admission was 57 x 10(9)/litre, but there was a wide range of values (18-258 x 10(9)/litre). The median synovia...
The pharmacology of local anesthetics.
The Veterinary clinics of North America. Equine practice    December 1, 1991   Volume 7, Issue 3 489-500 doi: 10.1016/s0749-0739(17)30482-0
Day TK, Skarda RT.Understanding of the pharmacology of local anesthesia is important for selection of a local anesthetic for use in equine standing surgery. In general, the action potential is inhibited by local anesthetics by preventing the influx of sodium ions across the axonal membrane. The physicochemical properties of each local anesthetic determine the onset of action, potency, and duration of action. Procaine, chlorprocaine, lidocaine, and mepivacaine are the local anesthetics still used clinically in horses; lidocaine is the most widely used. The future of equine local anesthesia may see the introducti...
Perineural and spinal anesthesia.
The Veterinary clinics of North America. Equine practice    December 1, 1991   Volume 7, Issue 3 501-519 doi: 10.1016/s0749-0739(17)30483-2
Gaynor JS, Hubbell JA.Local and regional anesthetic techniques are useful tools for the equine practitioner. These techniques allow surgery to be performed without the risk and cost of general anesthesia. There are, however, risks associated with the local and regional techniques. Neurotoxicity, although rare, may occur when 200 mL or more of a local anesthetic are infiltrated in a short period of time to a 450-kg horse. More likely, horses may become ataxic after nerve blockade in the limbs. This ataxia may lead to self trauma because the horse may not know where the limbs are actually being placed. Although local...
Endoscopic examination of normal paranasal sinuses in horses.
Veterinary surgery : VS    November 1, 1991   Volume 20, Issue 6 418-423 doi: 10.1111/j.1532-950x.1991.tb00350.x
Ruggles AJ, Ross MW, Freeman DE.The frontal, caudal maxillary, and rostral maxillary sinuses of 10 equine cadavers were examined endoscopically, and the findings were confirmed by sinusotomy. Similar endoscopic examinations were performed in five conscious, adult horses by using sedation and local anesthesia. Useful portals of entry for the arthroscope in adult horses were: for the frontal sinus, 60% of the distance in a lateral direction from midline to the medial canthus and 0.5 cm caudal to the medial canthus; for the caudal maxillary sinus, 2 cm rostral and 2 cm ventral to the medial canthus; and for the rostral maxillar...
Repair of an open radial fracture in an adult horse.
Journal of the American Veterinary Medical Association    August 1, 1991   Volume 199, Issue 3 364-367 
Baxter GM, Moore JN, Budsberg SC.An open radial fracture in an adult horse (450 kg) was repaired by internal fixation, using two 18-hole 4.5-mm broad dynamic compression plates and 5.5- and 4.5-mm bone screws. The fracture healed completely, but when evaluated 9 months after surgery, the horse was lame on the fractured limb at a trot. Local infiltration of anesthesia along the distal half of the bone plates greatly ameliorated the lameness, suggesting that the plates were irritating the soft tissues and extensor tendons along the cranial and lateral aspects of the antebrachium. Both bone plates were removed simultaneously wit...
Anatomical and functional communications between the synovial sacs of the equine stifle joint.
Equine veterinary journal    May 1, 1991   Volume 23, Issue 3 215-218 doi: 10.1111/j.2042-3306.1991.tb02759.x
Reeves MJ, Trotter GW, Kainer RA.The anatomical and functional communications of the synovial sacs of the equine stifle joint were evaluated in 50 stifle joints of 25 horses. Femoropatellar joint (FPJ) sacs were injected with 50 ml of gelatin-based dye and horses were then walked for 50 m. Horses were subsequently killed, the stifle joints dissected and the location of the dye recorded. Twenty-three horses (46 joints) had clinically normal stifle joints and in this group, anatomical communications of the stifle joints were bilaterally symmetrical in each horse. In 15 of these 23 horses (65 per cent), direct anatomical communi...
Regional anesthesia.
The Veterinary clinics of North America. Equine practice    December 1, 1990   Volume 6, Issue 3 693-704 doi: 10.1016/s0749-0739(17)30538-2
LeBlanc PH.Organ toxicity from local anesthetic agents is rare. This makes these agents an attractive option in the high-risk patient. Complications associated with local anesthetics are related to overdosage. Overdosage with local anesthetic agents administered epidurally may cause motor paralysis and hind-limb weakness. Systemic signs of local anesthetic overdosage include changes in central nervous system activity (excitement or depression), muscle tremors, and hypotension. Because the dose required to produce these effects in the horse is high (12 mg/kg), this complication is uncommon. Few side effec...
Local anesthetic techniques for diagnosis of lameness.
The Veterinary clinics of North America. Equine practice    December 1, 1990   Volume 6, Issue 3 705-728 doi: 10.1016/s0749-0739(17)30539-4
Schmotzer WB, Timm KI.Successful diagnostic local anesthesia is dependent upon a thorough knowledge of appendicular anatomy, application of correct technique, and accurate interpretation. Use of cadaver specimens to review anatomy and practice needle placement is strongly recommended. A marker solution, such as new methylene blue, can be injected into cadaver limbs, which can be subsequently dissected to verify accuracy. Detailed interpretation of local anesthetic blocks in the lame horse reaches beyond the scope of this article. Interpretive difficulties, however, can be responsible for the failure of a block to p...
Local anesthetics and nuclear medical bone images of the equine fore limb.
Veterinary surgery : VS    March 1, 1990   Volume 19, Issue 2 131-135 doi: 10.1111/j.1532-950x.1990.tb01154.x
Gaughan EM, Wallace RJ, Kallfelz FA.The effects of two local anesthetic agents on the diagnostic quality of nuclear medical bone images (NMBIs) of distal parts of the equine fore limb were investigated. Local effects on bone uptake of technetium 99m methylene diphosphonate (99mTc-MDP) 4 and 24 hours after perineural and intraarticular injection of mepivacaine hydrochloride and bupivacaine hydrochloride were evaluated in the carpal and metacarpophalangeal regions of 12 horses and ponies. Neither mepivacaine hydrochloride nor bupivacaine hydrochloride significantly altered the diagnostic quality of the NMBIs. The injection and sub...
Changes in equine carpal joint synovial fluid in response to the injection of two local anesthetic agents.
The Cornell veterinarian    January 1, 1989   Volume 79, Issue 1 25-38 
White KK, Hodgson DR, Hancock D, Parry BW, Cordell C.The effects of repeated arthrocentesis and injection of local anesthetic agents, lidocaine HCl or mepivacaine HCl on the equine middle carpal joint were investigated. Synovial fluid samples were evaluated before, and 12, 24 and 48 hours following, treatment. The greatest changes from pretreatment values occurred in synovial fluid cellularity. Repeated arthrocentesis caused a moderate increase in cell counts, while injection of local anesthetics caused a greater increase. Alterations in mucin clot quality, hyaluronic acid content, fluid viscosity, total protein and immunoglobulin G were general...
Epidural injection of xylazine for perineal analgesia in horses.
Journal of the American Veterinary Medical Association    December 1, 1988   Volume 193, Issue 11 1405-1408 
LeBlanc PH, Caron JP, Patterson JS, Brown M, Matta MA.Local anesthetics given in the epidural space of a horse may cause hind limb weakness in addition to analgesia. Because alpha 2 agonists given by epidural injection cause sensory blockade without motor effects in human beings and other species, their use in veterinary anesthesia is appealing. This study was designed to examine the effectiveness of xylazine HCl, an alpha 2 agonist commonly used in horses. Xylazine, 0.9% NaCl, and lidocaine were given by epidural injection to horses subjected to perineal electrical stimulation. Administration of xylazine (0.17 mg/kg of body weight, diluted to a ...
Some observations on lameness associated with pain in the proximal metacarpal region.
Equine veterinary journal. Supplement    September 1, 1988   Issue 6 43-52 doi: 10.1111/j.2042-3306.1988.tb04647.x
Dyson S.The carpus and metacarpus of 40 horses which were free from lameness and 40 horses with lameness associated with the metacarpophalangeal joint or more distal limb were examined radiographically (Group A). The opacity of the proximal third of the third metacarpal bone was regular, with a uniform trabecular pattern. Osseous cyst-like lesions (OCLLs) were identified in the radial carpal bone (1), the ulnar carpal bone (2), the second carpal bone (15) and the fourth carpal bone (1). Thirty-one of 638 horses (4.8 percent) with forelimb lameness had pain localised to the proximal metacarpal region u...
Actions of BW540C in an equine model of acute inflammation: a preliminary study.
The veterinary quarterly    April 1, 1987   Volume 9, Issue 2 103-110 doi: 10.1080/01652176.1987.9694086
Higgins AJ, Lees P, Sedgwick AD.An equine model of acute non-immune inflammation has been developed to facilitate studies of the inflammatory process and the actions of novel anti-inflammatory drugs. Five polyester sponge strips soaked in sterile 2% carrageenin solution were placed in subcutaneous pouches prepared under local anaesthesia in the necks of conscious ponies. Serial removal of the strips and harvesting of the exudate enabled studies to be made of the cellular, biochemical and mediator aspects of the localised, acute inflammation, and the heat generated by the lesion was monitored by infra-red thermometry. Maximal...
Diagnostic techniques in the investigation of shoulder lameness.
Equine veterinary journal    January 1, 1986   Volume 18, Issue 1 25-28 doi: 10.1111/j.2042-3306.1986.tb03530.x
Dyson S.Methods of investigating horses with suspected shoulder lameness are described and discussed. The gait of shoulder lameness is characterised and compared with that of lower forelimb lameness. If lameness is slight, differentiation may be difficult, but if moderate, upper forelimb lameness usually results in shortening of the cranial phase of the stride and a low limb flight. Clinically, it may not be possible to differentiate between shoulder and elbow lameness without intra-articular anaesthesia. Practical aspects of intra-articular anaesthesia of the shoulder joint are reviewed. Synovial flu...
Neodymium (Nd):YAG laser surgery in the equine larynx: a pilot study.
Lasers in surgery and medicine    January 1, 1986   Volume 6, Issue 5 473-476 doi: 10.1002/lsm.1900060511
Tate LP, Newman HC, Cullen JM, Sweeney C.Laryngeal surgery in the equine is customarily and routinely performed by means of a ventral laryngotomy incision. Such procedures are usually performed under deep general anesthesia with the horse in dorsal recumbency. The objective of this work was to determine the efficacy of an endoscopic approach coupled to a Nd:YAG laser fiber in performing arytenoidectomy. Arytenoidectomy is commonly indicated in the treatment of arytenoid chondritis and in the failure of prosthetic implantation for left laryngeal hemiplegia. This preliminary study was undertaken to determine the feasibility of the endo...
Pudendal and caudal rectal nerve blocks in the horse – An anesthetic procedure for reproductive surgery.
Theriogenology    October 1, 1985   Volume 24, Issue 4 457-464 doi: 10.1016/0093-691x(85)90052-4
Schumacher J, Bratton GR, Williams JW.The pudendal and caudal rectal nerves in four male and five female adult crossbred horses were anesthetized with a local solution. The injection site was located at the foramen for the caudal gluteal artery and vein in the sacrosciatic ligament. Twenty milliliters of local anesthetic solution were injected via a 15-cm, 18-gauge needle. Quantitative data on anesthesia were determined from these injections. Dye was injected with the anesthetic in four additional horses so that accurate placement of the solution could be determined at postmortem examination. Satisfactory anesthesia of the anus, p...
Intra-articular anaesthesia of the equine hock.
In practice    May 1, 1985   Volume 7, Issue 3 92-96 doi: 10.1136/inpract.7.3.92
Dyson S.No abstract available
Spinal fluid concentrations of mepivacaine in horses and procaine in cows after thoracolumbar subarachnoid analgesia.
American journal of veterinary research    May 1, 1985   Volume 46, Issue 5 1020-1024 
Skarda RT, Muir WW, Ibrahim AI.The CSF concentrations of mepivacaine in 10 Standardbred horses and of procaine in 10 Holstein cows given the drugs by thoracolumbar subarachnoid injection were determined. Mepivacaine hydrochloride was injected into the horses (502 +/- 60.5 kg) at an average dosage of 30 mg (1.5 ml of 20 mg/ml solution). Analgesia was produced 7.5 +/- 4.3 minutes after injection, extended between spinal cord segments T13 and L3 on both sides of the spinal column, and lasted 47 +/- 18.7 minutes at the T18 dermatome. Procaine hydrochloride was injected into cows (614 +/- 51.5 kg) at a dosage ranging between 75 ...
Differential effects of phenylbutazone and local anesthetics on nociception in the equine.
European journal of pharmacology    December 15, 1984   Volume 107, Issue 1 35-41 doi: 10.1016/0014-2999(84)90088-8
Kamerling SG, Dequick DJ, Weckman TJ, Sprinkle FP, Tobin T.The effects of procaine, mepivacaine and phenylbutazone on pain perception in the equine were studied using two behavioral assays of nociception; the thermal evoked hoof withdrawal reflex and skin twitch reflex. Pain perception threshold was measured as the latency from onset of thermal stimuli to reflex withdrawal of the forelimb or contraction of the cutaneous musculature. Procaine 2% and mepivacaine 2% prolonged the hoof withdrawal reflex latency when administered locally by producing a block of the palmar and metacarpal nerves. Significant analgesia lasted 90 min and 210 min for procaine a...
Survey of positive results from racecourse antidoping samples received at Racecourse Security Services’ Laboratories.
Equine veterinary journal    January 1, 1984   Volume 16, Issue 1 39-42 doi: 10.1111/j.2042-3306.1984.tb01846.x
Moss M S..A review of positive Jockey Club "dope tests" during the 12 years from 1970 to 1981 inclusive is presented and a comparison made with certain overseas racing authorities for varying periods between 1975 and 1981. Urinary pH of post race urine samples is predominantly acidic (although varying in a significant manner throughout the year) and thus favours excretion of the generally more potent basic drugs. The proportion of positive results was about the same in winners and non-winners, ie, one in 400 horses sampled. Drugs found fell mainly into four categories: methylxanthines; non-steroidal ant...
Fractures of the central and third tarsal bones in horses.
Journal of the American Veterinary Medical Association    June 1, 1983   Volume 182, Issue 11 1234-1238 
Tulamo RM, Bramlage LR, Gabel AA.The case histories and follow-up data for 11 horses with slab fractures of the central or 3rd tarsal bones were examined for information pertaining to the diagnosis, which was difficult to identify, treatment, which was proven ineffective, and the prognosis, which was shown to be poor for return to racing. The purpose of the study was to define the results that could be obtained by nonoperative methods, in an attempt to determine whether surgical treatment was advisable. Nine of the horses were Standardbreds and 2 were Thoroughbreds; all horses were 2 to 4 years old and were being exercised at...
Percutaneous lung biopsy in the horse.
The Cornell veterinarian    October 1, 1981   Volume 71, Issue 4 439-448 
Raphel CF, Gunson DE.Percutaneous lung biopsies with a cutting needle (Vim Tru Cut) were obtained from 20 horses. The procedure was performed in standing horses under a local anesthesia without sedation. All lung tissue specimens were suitable for histologic examinations and contained both pulmonary parenchyma and large airways. The only complication was hemoptysis in 2 (10%) horses which required no therapy. All horses were subsequently killed, and no gross abnormalities were present at the biopsy site.
Detection of some local anesthetics in horse urine and plasma by gas-liquid chromatography.
Journal of chromatography    February 27, 1981   Volume 206, Issue 3 594-599 doi: 10.1016/s0021-9673(00)88931-1
Delbeke FT, Debackere M, Desmet N.No abstract available
Avulsion fractures of the origin of the suspensory ligament of the horse.
Journal of the American Veterinary Medical Association    May 15, 1980   Volume 176, Issue 10 Pt 1 1004-1010 
Bramlage LR, Gabel AA, Hackett RP.Five horses with avulsion fractures of the proximal origin of the suspensory ligament were examined for lameness. The horses in the series each had lameness of acute onset; four were severely lame, and one was moderately lame. The condition was difficult to diagnose because commonly used local anesthetic blocks did not result in improvement during the routine examination. Local infiltration of the area with local anesthetic returned the horses to soundness. After a period of rest, varying from a few weeks in the acute injury to 6 months in the chronic injuries, the horses were returned to raci...
Diagnosis, relative incidence, and probable cause of cunean tendon bursitis-tarsitis of Standardbred horses.
Journal of the American Veterinary Medical Association    November 15, 1979   Volume 175, Issue 10 1079-1085 
Gabel AA.A prospective study of the diagnostic results on 25 previously untreated, slightly lame Standardbred horses showed that manipulative tests are of some help in diagnosis. The lameness of each horse was diminished or the horse went lame on the opposite limb after being given an injection of anesthetic in the cunean bursa, and lameness improved more when local anesthetic was injected in the distal intertarsal and tarsometatarsal articulations. In four horses, lesions of the distal articulation of the hock were evident on radiography.
[Local anesthesia in the examination for lameness].
Berliner und Munchener tierarztliche Wochenschrift    May 1, 1978   Volume 91, Issue 9 166-171 
Zeller R.No abstract available
[Studies on diffusion of local anesthetic solutions from the hoof-joint in the bursa podotrochlearis in the horse].
Schweizer Archiv fur Tierheilkunde    June 1, 1976   Volume 118, Issue 6 233-238 
Wintzer HJ, Frey HH, Fitzek A.No abstract available