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Topic:Parasites

Parasites are organisms that live on or within a host, deriving nutrients at the host's expense. In horses, parasitic infections can affect various systems, including the gastrointestinal tract, skin, and respiratory system. Common equine parasites include strongyles, ascarids, tapeworms, and bots. These parasites can lead to a range of health issues, from mild discomfort to severe disease, depending on the type and burden of the infestation. This page compiles peer-reviewed research studies and scholarly articles that explore the biology, life cycle, and impact of parasites on equine health, as well as strategies for diagnosis, treatment, and prevention of parasitic infections in horses.
Plasma thromboxane B2 levels in horses experimentally infected with Strongylus vulgaris.
Equine veterinary journal. Supplement    June 1, 1989   Issue 7 14-18 doi: 10.1111/j.2042-3306.1989.tb05647.x
Cambridge H, Reynoldson JA, Dunsmore JD.Plasma thromboxane B2 (TXB2) the stable inactive metabolite of thromboxane A2 (TXA2), was measured daily by specific radioimmunoassay in three groups of animals before and after experimental infection with Strongylus vulgaris. Infection of four 'parasite naive' foals produced a typical acute syndrome with intermittent but statistically insignificant rises in TXB2 levels. Interpretation of results was complicated by the presence of a non-septic peritonitis associated with implantation of the foals with electrodes for recording myoelectrical activity. In two foals of similar age, with some natur...
Critical and controlled tests of activity of a macrocyclic lactone (compound F28249-alpha) against natural infections in internal parasites of equids.
American journal of veterinary research    June 1, 1989   Volume 50, Issue 6 970-974 
Lyons ET, Drudge JH, Tolliver SC.Thirteen critical tests (n = 11 horses and 2 ponies) and 4 controlled tests (n = 4 donkeys and 6 horses) were performed to evaluate the activity of the experimental macrocyclic lactone compound F28249-alpha against internal parasites of equids. In the critical tests, activity was determined mainly against the large parasites, but 1 critical test also included benzimidazole-resistant small strongyles. In the controlled tests, evaluation of drug activity included large parasites and stomach worms in all 4 tests, and lungworms in 2 tests. The period between treatment and euthanasia was 6 to 9 day...
Protection of yearling ponies against Strongylus vulgaris by foalhood vaccination.
Equine veterinary journal. Supplement    June 1, 1989   Issue 7 2-7 doi: 10.1111/j.2042-3306.1989.tb05645.x
Klei TR, French DD, Chapman MR, McClure JR, Dennis VA, Taylor HW, Hutchinson GW.The long-term efficacy of an irradiation attenuated larval (L3) vaccine against Strongylus vulgaris was tested in ponies which were reared on pasture. Prior to foaling, mares were divided into two groups. One group of mares and foals received regular (eight weekly) treatment with ivermectin and the second group remained untreated. Half the foals in each pasture group were vaccinated at eight to ten weeks of age. Foals were weaned at three to four months of age and maintained on separate pastures. At eight to ten months of age, ponies were placed in box stalls and half of each treatment group w...
Benzimidazole resistance in a herd of horses.
The Veterinary record    May 27, 1989   Volume 124, Issue 21 560-561 doi: 10.1136/vr.124.21.560
Love S, McKellar QA, Duncan JL.No abstract available
Effect of repeated oxfendazole treatments on small strongyle infections in Shetland ponies.
Research in veterinary science    May 1, 1989   Volume 46, Issue 3 409-412 
Eysker M, Boersema JH, Kooyman FN.Overwintering of horse cyathostomes as inhibited third stage larvae (L3) and the effect of repeated oxfendazole (OFZ) treatment on strongyle infections were studied in an experiment with two groups of three Shetland ponies. Both groups were grazed together from May 28 to November 11, 1986 and subsequently housed. Treatments with 10 mg OFZ kg-1 were given on May 26, July 1 and July 28 and again one week before each group was necropsied in December and April, respectively. Worm populations of both groups were dominated by inhibited early L3. The proportion of fourth stage larvae (L4) was signifi...
Observations on the occurrence of five species of Gasterophilus larvae in free-ranging horses in Umbria, central Italy.
Veterinary parasitology    May 1, 1989   Volume 31, Issue 2 173-177 doi: 10.1016/0304-4017(89)90032-0
Principato M.Comparative data collected over 4 years show the most frequent species of Gasterophilus infesting free-ranging horses in Umbria (Central Italy) to be G. intestinalis (93.8%), G. nasalis (76.5%) and G. inermis (71%). G. pecorum and G. haemorrhoidalis were less frequent and appeared in 39.3 and 10.8% of the animals, respectively. For each of the 5 species, the duration of gastric and enteric lesions, the average numbers of larvae isolated throughout the year and the probable duration of oral lesions were discussed.
[Finding Setaria equina in horses].
Angewandte Parasitologie    May 1, 1989   Volume 30, Issue 2 127-130 
Buchwalder R, Schuster R.For the first time findings of Setaria equina (Abildgaard, 1789) in horses are reported from the German Democratic Republic. The nematodes, located in the peritoneum, were discovered in the course of autopsy. Based on a thorough analysis of the international literature, the paper discusses geographical distribution, morphology, cycle and diagnosis of this nematode as well as clinical symptoms mainly caused by the stages of the larvae.
Experimental trichinellosis in horses: biological and parasitological evaluation.
Veterinary parasitology    April 1, 1989   Volume 31, Issue 1 19-36 doi: 10.1016/0304-4017(89)90005-8
Soule C, Dupouy-Camet J, Georges P, Ancelle T, Gillet JP, Vaissaire J, Delvigne A, Plateau E.Three groups of three horses each were, respectively, infected with 5000, 20,000 and 50,000 larvae of Trichinella spiralis. The strain used was isolated from a human biopsy during horsemeat-related outbreaks of trichinellosis in France. Transient muscular disorders were only observed in two of the horses infected with 50,000 larvae but none of the horses had fever. A significant increase in blood eosinophils was noticed in 5 horses. Serum LDH, aldolase and CPK peaked at the fifth week post-infection. Specific IgG assayed by indirect immunofluorescence and ELISA, appeared 2-5 weeks post-infecti...
Repetitive DNA probes for the detection of Babesia equi.
Molecular and biochemical parasitology    April 1, 1989   Volume 34, Issue 1 75-78 doi: 10.1016/0166-6851(89)90021-2
Posnett ES, Ambrosio RE.This report describes DNA probes for the identification of Babesia equi. A genomic library of B. equi was constructed in pUC13. Several clones were identified that hybridized strongly to B. equi DNA. Clone pBE33 hybridized specifically to B. equi DNA and did not hybridize to horse DNA nor to DNA from Babesia caballi, Babesia bovis or Babesia bigemina. Two subclones of pBE33 (pSB20 and pEH21) containing B. equi repetitive sequences, could detect 0.49 ng and 0.97 ng B. equi DNA, respectively.
Prevalence of Cryptosporidium sp in equids in Louisiana.
American journal of veterinary research    April 1, 1989   Volume 50, Issue 4 575-577 
Coleman SU, Klei TR, French DD, Chapman MR, Corstvet RE.In 1985, 22 pony foals reared in a helminth-free environment were tested daily for oocysts of Cryptosporidium sp by use of fecal flotation. Oocysts were found in all foals. Oocysts were first observed in feces collected from foals 9 to 28 days after birth. The mean period of oocyst shedding was 10 days and ranged from 2 to 18 days in individual foals. Diarrhea was observed in 14 of 22 (64%) foals and began before the period of oocyst shedding. Fecal samples also were examined for other infective agents. Salmonella poona was isolated from 1 foal that did not have diarrhea, and coronavirus parti...
Determination of the efficacy of pyrantel pamoate at the therapeutic dose rate against the tapeworm Anoplocephala perfoliata in equids using a modification of the critical test method.
Veterinary parasitology    April 1, 1989   Volume 31, Issue 1 13-18 doi: 10.1016/0304-4017(89)90004-6
Lyons ET, Drudge JH, Tolliver SC, Swerczek TW, Collins SS.A total of 59 equids (54 horses and five Shetland ponies) were treated with pyrantel pamoate once, at the dose rate of approximately 6.6 mg base kg-1, during the period November 1985-January 1988. The drug was administered as a paste formulation (51 equids) intraorally or as a suspension formulation by stomach tube (eight equids). The purpose of treatment was to evaluate the activity of pyrantel pamoate (at the therapeutic dose rate) for removal of the tapeworm, Anoplocephala perfoliata, by a modified (24-h) critical test. The presence or absence of tapeworms was not determined for the equids ...
Benzimidazole resistance in horses in western Canada.
The Canadian veterinary journal = La revue veterinaire canadienne    February 1, 1989   Volume 30, Issue 2 173-174 
Piché CA, Kennedy MJ, Bauck S.No abstract available
Echinococcus granulosus: a comparison of free amino acid concentration in hydatid fluid from primary and secondary cysts and host plasma.
Parasitology    February 1, 1989   Volume 98 ( Pt 1) 135-143 doi: 10.1017/s0031182000059771
Hurd H.A total of 28 components were detected in the free amino acid (FAA) pool of hydatid fluid from primary and secondary equine cysts, secondary ovine cysts and host plasma. Examination of data from equine cysts revealed that the majority of FAAs were present in significantly greater concentrations in secondary cysts, glycine being over 30 times more concentrated. Values for total carbohydrates and glucose did not, however, differ significantly and total protein content was greater in primary cysts. Comparison of the (FAA) pool of secondary equine and ovine cysts revealed strain variation. It was ...
The epidemiology of Echinococcus granulosus in Great Britain. V. The status of subspecies of Echinococcus granulosus in Great Britain.
Annals of tropical medicine and parasitology    February 1, 1989   Volume 83, Issue 1 51-61 doi: 10.1080/00034983.1989.11812310
Cook BR.Twenty-five years ago Williams and Sweatman suggested that in Great Britain there are two subspecies of Echinococcus granulosus--E. granulosus granulosus and E. granulosus equinus. Echinococcus granulosus granulosus does not mature either in foxes or in horses: E. granulosus equinus will mature in either. The prepatent period of E. granulosus granulosus in the definitive host is about 42 days while that of E. granulosus equinus is about 70 days. Each subspecies has a characteristic morphology. More recently, in the course of seven experiments, dogs, red foxes (Vulpes vulpes crucigera), arctic ...
Caecal intussusceptions in horses and the significance of Anoplocephala perfoliata.
The Veterinary record    January 14, 1989   Volume 124, Issue 2 34-37 doi: 10.1136/vr.124.2.34
Owen RA, Jagger DW, Quan-Taylor R.A caecocaecal intussusception in a pony and a caecocolic intussusception in a horse, both infected with Anoplocephala perfoliata, are described and the relevance of tapeworms in such intestinal disease of horses is reviewed.
A Hypoderma diana (Diptera: Hypodermatidae) infection in a horse.
The veterinary quarterly    January 1, 1989   Volume 11, Issue 1 56-57 doi: 10.1080/01652176.1989.9694197
Hendrikx WM, Jansen J, de Vries TJ.An infection with second-stage larvae of the warble-fly H. diana in a horse is described. The second-stage larvae were incapable of developing into the third stage, because horses are unsuitable hosts and because the infected horse was treated with an insecticide. Since the horse was used for dragging trees in the forests, the infection was likely contracted via contact with H. diana, a normal parasite of roe deer in the Netherlands.
Prevalence and intensity of non-strongyle intestinal parasites of horses in northern Queensland.
Australian veterinary journal    January 1, 1989   Volume 66, Issue 1 23-26 doi: 10.1111/j.1751-0813.1989.tb09708.x
Mfitilodze MW, Hutchinson GW.A quantitative post-mortem study of 57 horses from northern Queensland was done to determine the prevalence and intensity of non-strongyle intestinal parasites. The following species (% prevalence) were found: Draschia megastoma (39%); Habronema muscae (43%); Gasterophilus intestinalis (34%), G. nasalis (30%); Parascaris equorum (15%); Strongyloides westeri (6%); Probstmayria vivipara (2%); Oxyuris equi (26%); Anoplocephala magna (2%); A. perfoliata (32%). Mean parasite numbers of individual species ranged from 10 to 1310. Prevalence and intensity data were compared to recent studies in Wester...
[Experimental equine fascioliasis: evolution of serologic, enzymatic and parasitic parameters].
Annales de recherches veterinaires. Annals of veterinary research    January 1, 1989   Volume 20, Issue 3 295-307 
Soulé C, Boulard C, Levieux D, Barnouin J, Plateau E.Three, four, and one horses were respectively infected with 100, 1,000, and 5,000 metacercariae of Fasciola hepatica. Six of them were reinfected 38 weeks later with 1,000 metacercariae each. Specific antibodies assayed by counter-electrophoresis, passive hemagglutination and ELISA tests appeared three to six weeks post-infection and peaked 10 to 17 weeks post-infection. Horses infected by 1,000 metacercariae and more showed 17.6% of positive samples by counter-electrophoresis, 49.2% by ELISA, and 75.6% by passive hemagglutination. Plasma glutamate dehydrogenase and gamma-glutamyltransferase l...
Preliminary investigations on the effects of a Strongylus vulgaris larval extract, mononuclear factors and platelet factors on equine smooth muscle cells in vitro.
Veterinary research communications    January 1, 1989   Volume 13, Issue 6 479-489 doi: 10.1007/BF00402572
Morgan SJ, Storts RW, Stromberg PC, Sowa BA, Lay JC.Factors involved in the proliferation of equine vascular smooth muscle cells were studied in vitro. The most prominent proliferative responses in cultured vascular smooth muscle cells were induced by Strongylus vulgaris larval antigen extract (LAE) and platelet-derived factors. Less significant proliferative responses were obtained with conditioned media from S. vulgaris LAE stimulated and from unstimulated equine mononuclear leukocytes. Additionally, vascular smooth muscle cells exposed to S. vulgaris LAE developed numerous perinuclear vacuoles and were more spindle-shaped than control or smo...
[Benzimidazole resistance in small strongylids (Cyathostominae): distribution in horse stock in Northrhine-Westphalia].
Berliner und Munchener tierarztliche Wochenschrift    December 1, 1988   Volume 101, Issue 12 406-408 
Ullrich D, Bauer C, Bürger HJ.No abstract available
Studies on the effect of short term, high dose praziquantel treatment against protoscoleces of ovine and equine Echinococcus granulosus within the cyst, and in vitro. Richards KS, Riley EM, Taylor DH, Morris DL.Protoscoleces of Echinococcus granulosus were subjected to high concentrations of praziquantel (10-1000 micrograms/ml medium or cyst fluid) for a short, 10 min duration in vitro or in situ within cysts. Drug efficacy was then monitored either by in vitro culture in drug-free medium and/or by passage into rodents. The in vitro test of effectiveness suggested that ovine-derived protoscoleces were more sensitive than those of equine origin, and that the in vitro method of treatment was more successful than that performed in situ. However, the subsequent passage of treated protoscoleces, whether i...
Effectiveness of an ivermectin liquid formulation given by nasogastric tube against strongyles in horses.
The Canadian veterinary journal = La revue veterinaire canadienne    December 1, 1988   Volume 29, Issue 12 986-988 
Slocombe JO, Cote JF.Twenty horses were treated with ivermectin either by nasogastric tube with a liquid formulation for sheep or per os with a paste formulation for horses at a dosage of 200 mug/kg of body weight. Fecal samples were collected from these horses and from ten untreated horses at the time of treatment and every 2 wk thereafter for up to 10 wk. The samples were examined for nematode eggs using the Cornell-McMaster dilution and the Cornell-Wisconsin Double Centrifugation procedures.There were no signs of toxicosis in horses treated with ivermectin. Strongyle eggs were found in the feces of all horses b...
In vivo activation of equine eosinophils and neutrophils by experimental Strongylus vulgaris infections.
Veterinary immunology and immunopathology    December 1, 1988   Volume 20, Issue 1 61-74 doi: 10.1016/0165-2427(88)90026-8
Dennis VA, Klei TR, Chapman MR, Jeffers GW.Eosinophils and neutrophils from ponies with Strongylus vulgaris-induced eosinophilia (eosinophilic ponies; activated eosinophils and neutrophils) were assayed in vitro for chemotactic and chemokinetic responses to zymosan-activated serum (ZAS) using the filter system in Boyden chambers, for Fc and complement (C) receptors using the EA and EAC-rosette assays, respectively, and for phagocytic and bactericidal activities using opsonized Escherichia coli and the acridine orange method. The responses of activated eosinophils and neutrophils in the above assays were compared with those of eosinophi...
Ivermectin in equine lichen tropicus.
The Veterinary record    November 26, 1988   Volume 123, Issue 22 583 doi: 10.1136/vr.123.22.583-b
Raisinghani PM, Kumar D.No abstract available
Prevalence of Anoplocephala perfoliata in horses and ponies in Clwyd, Powys and adjacent English marches.
The Veterinary record    November 26, 1988   Volume 123, Issue 22 562-563 doi: 10.1136/vr.123.22.562
Owen RA, Jagger DW, Quan-Taylor R.The prevalence of Anoplocephala perfoliata in 103 horses and ponies from Clwyd, Powys and the adjacent English marches, slaughtered during January 1987, was 69 per cent.
Hematochezia attributable to cranial mesenteric arterial aneurysm with connecting tracts to cecum and ileum in a horse.
Journal of the American Veterinary Medical Association    November 15, 1988   Volume 193, Issue 10 1278-1280 
Kiper ML, MacAllister C, Qualls C.A cranial mesenteric arterial aneurysm with fistulous tracts to the cecum and ileum was discovered in a Missouri Fox Trotter stallion. The principal clinical sign was hematochezia, observed at 7- and 10-day intervals. The lesion may have been attributable to arteritis caused by fourth-stage larvae of Strongylus vulgaris.
Prevalence of Eimeria leuckarti (Flesch, 1883) and intensity of faecal oocyst output in a herd of horses during a summer grazing season.
Veterinary parasitology    November 1, 1988   Volume 30, Issue 1 11-15 doi: 10.1016/0304-4017(88)90138-0
Bauer C.The prevalence of Eimeria leuckarti infection and the intensity of faecal oocyst output were determined in a herd of 14 mares and their foals in northwest Germany using a sedimentation technique at weekly intervals during a summer grazing season from May to September. None of the mares, but all foals shed oocysts on at least one occasion. The patent periods lasted up to 16 weeks. The mean intensity of oocyst output (0.1-33 o.p.g.) was very low. No clinical signs of gastrointestinal disorder were noticed in any of the foals during this study.
Preferred landing sites of Culicoides species (Diptera: Ceratopogonidae) on a horse in Israel and its relevance to summer seasonal recurrent dermatitis (sweet itch).
Equine veterinary journal    November 1, 1988   Volume 20, Issue 6 426-429 doi: 10.1111/j.2042-3306.1988.tb01566.x
Braverman Y.Six hundred and twenty culicoides of five species were collected from a bait horse at Kannot, Israel, between April and September 1986. Seventy-two per cent of the midges were collected from the belly and 27 per cent from the dorsal aspect of the body, ie, the sweet itch summer seasonal recurrent dermatitis (SSRD) zone. Midges were active mainly from half an hour prior to half an hour after sunset. Only Culicoides puncticollis, C imicola and C schultzei group were collected in considerable numbers. While C imicola was present continuously throughout the season, the appearance of the two other ...
Evaluation of ivermectin for larvicidal effect in experimentally induced Parascaris equorum infections in pony foals.
American journal of veterinary research    November 1, 1988   Volume 49, Issue 11 1983-1985 
DiPietro JA, Lock TF, Todd KS, Sanecki RK.A controlled test was carried out on 15 pony foals inoculated with 1,500 +/- 108.8 infective Parascaris equorum eggs. The foals were assigned to 3 treatment groups. Treatments given on postinoculation day 11 included 0.2 mg of ivermectin/kg of body weight, formulated as paste (n = 5), or liquid (n = 5), or no treatment (controls; n = 5). The foals were euthanatized on postinoculation day 25, and examined for larvae in the small intestine, lungs, and liver. Larvae were not found in foals treated with ivermectin liquid or paste, whereas significantly (P less than 0.05) higher mean numbers (960.9...
World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) guidelines for evaluating the efficacy of equine anthelmintics.
Veterinary parasitology    November 1, 1988   Volume 30, Issue 1 57-72 doi: 10.1016/0304-4017(88)90142-2
Duncan JL, Arundel JH, Drudge JH, Malczewski A, Slocombe JO.These guidelines have been designed to assist in the planning, operation and interpretation of studies which would serve to assess the efficacy of drugs against internal parasites of horses. Although the term anthelmintic is used in the title and text, these guidelines include studies on drug efficacy against larvae of horse bot flies, Gasterophilus spp, which are non-helminth parasites commonly occurring in the stomach of horses. The advantages, disadvantages and application of critical and controlled tests are presented. Information is also provided on selection of animals, housing, feed, do...
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