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Topic:Peritonitis

Peritonitis in horses refers to inflammation of the peritoneum, the thin membrane lining the abdominal cavity and covering the abdominal organs. This condition can result from various causes, including bacterial infections, gastrointestinal perforations, or abdominal trauma. Clinical signs in horses may include abdominal pain, fever, anorexia, and depression. Diagnosis typically involves clinical examination, blood tests, and abdominal fluid analysis. Treatment strategies often include antimicrobial therapy, anti-inflammatory medications, and supportive care. This page aggregates peer-reviewed research studies and scholarly articles that explore the etiology, pathophysiology, diagnostic methods, and treatment options for peritonitis in equine patients.
Retrospective analysis of the results of 151 exploratory laparotomies in horses with gastrointestinal disease.
Equine veterinary journal    September 1, 1993   Volume 25, Issue 5 427-431 doi: 10.1111/j.2042-3306.1993.tb02985.x
Phillips TJ, Walmsley JP.Of 149 horses that underwent 151 exploratory laparotomies for gastrointestinal disorders from September 1987 to May 1991, 107 (72%) were discharged from the hospital: 100 (66%) survived for > 7 months, 94 of which returned to their intended use. Survival rate (64/80) for horses with caecum/large colon obstruction was significantly (P = 0.003) higher than for horses with small intestinal obstruction (33/64). Prolonged surgery was associated with significantly (P < 0.001) lower survival rates than short surgical time. In the large intestine, survival rate (15/29) for strangulated obstructions wa...
Peritonitis in horses: 67 cases (1985-1990).
Journal of the American Veterinary Medical Association    July 15, 1993   Volume 203, Issue 2 284-288 
Hawkins JF, Bowman KF, Roberts MC, Cowen P.Peritonitis was diagnosed in 67 horses between 1985 and 1990: 14 horses developed septic peritonitis after intestinal rupture, 25 horses developed peritonitis after abdominal surgery, and 28 horses had peritonitis not associated with intestinal rupture or abdominal surgery. Forty of 67 horses (59.7%) did not survive. Nonsurvivors had higher heart rates (P = 0.01), RBC count (P = 0.039), serum creatinine concentration (P = 0.036), PCV (P = 0.007), and anion gap (P = 0.005); lower venous blood pH (P = 0.002); and a greater number of bacterial species cultured from peritoneal fluid samples (P = 0...
What is your diagnosis? Radiopaque foreign body (10 x 15 mm) in the pelvic inlet and free peritoneal gas.
Journal of the American Veterinary Medical Association    May 1, 1993   Volume 202, Issue 9 1501-1502 
Walker WB, Williams MA, Humburg JM, Jones JC.No abstract available
Clostridium septicum septicemia in a neonatal foal with hemorrhagic enteritis.
The Cornell veterinarian    April 1, 1993   Volume 83, Issue 2 143-151 
Jones SL, Wilson WD.Clostridium septicum was isolated by anaerobic culture of blood collected from a 3-day-old foal with hemorrhagic enteritis and signs suggestive of septicemia. The foal responded well to treatment with intravenous fluids, antibiotics, plasma, and oral gastrointestinal protectants. One month after apparent complete recovery from the septicemia and hemorrhagic enteritis, the foal was euthanized during an acute episode of colic that was caused by severe, strangulating intestinal adhesions, thought to have formed as a result of peritonitis secondary to the hemorrhagic enteritis. The value of anaero...
Chyloperitoneum associated with torsion of the large colon in a horse.
The Veterinary record    October 31, 1992   Volume 131, Issue 18 421 doi: 10.1136/vr.131.18.421
Mair TS, Lucke VM.No abstract available
Idiopathic muscular hypertrophy of the equine small intestine: 11 cases (1980-1991).
Equine veterinary journal    September 1, 1992   Volume 24, Issue 5 372-378 doi: 10.1111/j.2042-3306.1992.tb02858.x
Chaffin MK, Fuenteabla IC, Schumacher J, Welch RD, Edwards JF.The medical records of 11 horses with idiopathic muscular hypertrophy (MH) of the small intestine were reviewed to determine the clinical and pathological features of the disease. The median age of affected horses was 10.0 years (range 5-18 years). No breed or sex predisposition was apparent. Ten horses (91%) had chronic (23 days to 2.4 years) signs of mild, intermittent colic, and 1 horse had signs of severe colic of only 3 days' duration. Partial anorexia and chronic weight loss of variable duration (1-6 months) were prominent historical findings in 5 (45%) horses. Diagnostic tests, with the...
Septic peritonitis associated with caudal myotomy in a Tennessee walking horse.
Journal of the American Veterinary Medical Association    August 1, 1992   Volume 201, Issue 3 458-459 
Moll HD, Schumacher J.A 2-year-old Tennessee Walking Horse colt was admitted for evaluation of signs of abdominal pain, inappetence, and constipation of 5 days' duration. Two days prior to the onset of signs, the owner had cut the sacrococcygeal muscles as part of a tail-setting procedure. On examination, the horse was febrile and lethargic, and intestinal sounds were not heard on auscultation. Results of peritoneal fluid analysis were indicative of peritonitis. The horse continued to deteriorate and died despite treatment with antimicrobials, flunixin meglumine, and balanced electrolyte solution. At necropsy, the ...
Gastric ulceration in horses: 91 cases (1987-1990).
Journal of the American Veterinary Medical Association    July 1, 1992   Volume 201, Issue 1 117-120 
Murray MJ.Gastroendoscopy was performed on 111 horses (1 to 22 years old) that had signs of abdominal discomfort of variable duration and severity. At least 1 episode of colic had been observed within 48 hours of examination in 31 horses. Recurrent episodes of colic were observed in 28 horses within 2 to 10 days of examination, 31 horses within 11 to 30 days, 12 horses within 31 to 60 days, and in 9 horses at more than 60 days after the initial examination. Gastric ulceration was found in 91 of 111 horses examined. Other abnormalities involving the gastrointestinal tract or other abdominal viscera were ...
Conservative management of uroperitoneum in a gelding.
Journal of the American Veterinary Medical Association    June 1, 1992   Volume 200, Issue 11 1692-1694 
Gibson KT, Trotter GW, Gustafson SB.Uroperitoneum as a sequela to urethral calculus in an adult gelding was successfully managed by use of subischial urethrotomy and abdominal drainage. Necrosis of bladder mucosa was seen endoscopically, but a tear or rupture was never identified. Peritonitis developed but was controlled with antibacterial treatment. Although uroperitoneum is usually a sequela to bladder rupture and the ideal treatment is surgical repair, conservative management may be warranted in selected cases.
Septic cholangitis and peritonitis in a gelding.
Journal of the American Veterinary Medical Association    May 15, 1992   Volume 200, Issue 10 1521-1524 
Clabough DL, Duckett W.An 8-year-old Arabian gelding with septic cholangitis and peritonitis was successfully treated with trimethoprim/sulfadiazine. The gelding was referred for evaluation of signs of abdominal pain, icterus, fever, and weight loss. Peritoneal fluid analysis revealed septic and suppurative peritonitis. Culture of the peritoneal fluid yielded Escherichia coli and Klebsiella pneumoniae, which were sensitive to trimethoprim/sulfadiazine. On the basis of results of hepatic ultrasonography, a diagnosis of septic cholangitis also was made. The horse was treated with 30 mg of trimethoprim/sulfadiazine/kg,...
Mesenteric tears of the descending (small) colon as a postpartum complication in two mares.
Journal of the American Veterinary Medical Association    December 1, 1991   Volume 199, Issue 11 1612-1615 
Dart AJ, Pascoe JR, Snyder JR.Segmental ischemic necrosis of the descending colon associated with discrete tears of the mesocolon were diagnosed in 2 mares following foaling. After foaling, both mares had a slow onset of signs of abdominal pain and gradual deterioration of clinical status. Increases in peritoneal fluid total protein concentration and WBC count and a palpable impaction of the descending colon on examination per rectum were useful diagnostic aids. Surgical intervention was successful in one mare, but not in the other.
Clinical use of metronidazole in horses: 200 cases (1984-1989).
Journal of the American Veterinary Medical Association    March 15, 1991   Volume 198, Issue 6 1045-1048 
Sweeney RW, Sweeney CR, Weiher J.Case records of 200 horses treated with metronidazole were reviewed. Horses were treated for respiratory tract infections (90 cases), peritonitis or abdominal abscess (39 cases), celiotomy (49 cases), orthopedic infections (6 cases), and miscellaneous soft tissue infections (16 cases). Bacteria of the genus Bacteroides were most prevalent (55 of 167 anaerobic isolates). Metronidazole was always used in combination with other antimicrobial drugs. Only 4 of the 200 horses had signs of adverse effects associated with metronidazole treatment. Those 4 horses had poor appetite that resolved when met...
Induction of peritoneal adhesions with small intestinal ischaemia and distention in the foal.
Equine veterinary journal    March 1, 1991   Volume 23, Issue 2 144-145 
Adams R, Koterba A, Cudd T.No abstract available
Use of a liquid diet as the sole source of nutrition in six dysphagic horses and as a dietary supplement in seven hypophagic horses.
Journal of the American Veterinary Medical Association    October 15, 1990   Volume 197, Issue 8 1030-1032 
Sweeney RW, Hansen TO.Six horses with dysphagia (attributable to botulism, glossitis, or guttural pouch mycosis) were given a commercially available liquid diet as the sole source of nutrition. Seven horses with hypophagia caused by severe bacterial pleuropneumonia or peritonitis were given the liquid diet to supplement food consumed voluntarily. The liquid diet was administered through a nasogastric tube 2 or 3 times daily. Body weight did not change significantly, and pertinent laboratory values remained at satisfactory concentrations throughout the feeding period. Serious complications were not encountered. Thre...
Peritonitis in adult horses.
The Veterinary record    October 13, 1990   Volume 127, Issue 15 387-388 
van den Bogaard AE.No abstract available
Peritonitis in adult horses: a review of 21 cases.
The Veterinary record    June 9, 1990   Volume 126, Issue 23 567-570 
Mair TS, Hillyer MH, Taylor FG.The clinical signs in 21 adult horses affected by peritonitis (unassociated with gastrointestinal rupture or surgical interference of the abdomen) included colic (18 cases), pyrexia (15 cases), weight loss (six cases) and diarrhoea (five cases). The diagnosis was based on a nucleated cell count in peritoneal fluid greater than 10(10)/litre. Haematological abnormalities (either neutropenia or neutrophilia) were present in 17 animals, and hyperfibrinogenaemia was identified in 14. Twelve of the 21 horses survived after intensive antibiotic therapy; the other nine were destroyed either at explora...
Enteric pythiosis in a horse.
Journal of the American Veterinary Medical Association    February 1, 1990   Volume 196, Issue 3 462-464 
Allison N, Gillis JP.Enteric pythiosis was diagnosed in a 2-year-old Quarter Horse gelding. The horse had signs of colic, which appeared to be alleviated by administration of mineral oil and analgesics, but only temporarily. Intestinal distention developed after initial examination. At surgery, a thick stenotic area was observed in the middle portion of the jejunum. The thick intestine and associated mesentery contained multiple firm nodules of gritty caseous material. Histopathologic findings included sclerosing eosinophilic granulomatous enteritis and peritonitis. Although the lesion resembled a response to migr...
Induction of peritoneal adhesions with small intestinal ischaemia and distention in the foal.
Equine veterinary journal    November 1, 1989   Volume 21, Issue 6 451-458 doi: 10.1111/j.2042-3306.1989.tb02195.x
Lundin C, Sullins KE, White NA, Clem MF, Debowes RM, Pfeiffer CA.Twenty-two foals were divided into groups of intestinal distension and intestinal ischaemia as methods to induce peritoneal adhesions. In the first group, the lumen of a segment of distal small intestine was occluded without extramural vascular compromise and distended with lactated Ringer's solution to a constant pressure of 25 cm H2O for 2 h within the abdomen. The ischaemic group underwent 70 mins total vascular occlusion of identical segments of bowel. Serosal biopsies were obtained before and after each experimental procedure and following 60 mins of reperfusion. Similar biopsies were har...
Plasma thromboxane B2 levels in horses experimentally infected with Strongylus vulgaris.
Equine veterinary journal. Supplement    June 1, 1989   Issue 7 14-18 doi: 10.1111/j.2042-3306.1989.tb05647.x
Cambridge H, Reynoldson JA, Dunsmore JD.Plasma thromboxane B2 (TXB2) the stable inactive metabolite of thromboxane A2 (TXA2), was measured daily by specific radioimmunoassay in three groups of animals before and after experimental infection with Strongylus vulgaris. Infection of four 'parasite naive' foals produced a typical acute syndrome with intermittent but statistically insignificant rises in TXB2 levels. Interpretation of results was complicated by the presence of a non-septic peritonitis associated with implantation of the foals with electrodes for recording myoelectrical activity. In two foals of similar age, with some natur...
Small-colon rupture attributable to granulosa cell tumor in a mare.
Journal of the American Veterinary Medical Association    March 1, 1989   Volume 194, Issue 5 681-682 
Wilson DA, Foreman JH, Boero MJ, Didier PJ, Lerner DJ.A large granulosa cell tumor was believed to be responsible for causing obstruction and subsequent rupture of the small colon in a 10-year-old Quarter Horse mare. Two months earlier, a mass, tentatively diagnosed as granulosa cell tumor of the left ovary, had been identified by means of rectal palpation and ultrasonography. The mare was evaluated for clinical signs of acute, severe, abdominal pain, increased heart rate, cyanotic mucous membranes, clinical dehydration, with high PCV, leukopenia, and extreme abdominal distension. A large soft tissue mass and taut band that constricted the lumen ...
Evaluation of three techniques for end-to end anastomosis of the small colon in horses.
American journal of veterinary research    September 1, 1988   Volume 49, Issue 9 1613-1620 
Hanson RR, Nixon AJ, Calderwood-Mays M, Gronwall R.In an attempt to determine the best method for surgical removal of devitalized small colon lesions, 12 horses underwent a double small colon resection and end-to-end anastomosis. In 4 horses (study 1), an appositional single-layer (APP-1) suture pattern was compared with an inverting 2-layer (INV-2) suture pattern. In 8 horses (study 2), an appositional 2-layer (APP-2) suture pattern was compared with the INV-2 suture technique. Polydioxanone suture (size 1-0), was used. Horses were evaluated at necropsy 3, 10, 14, 28, or 56 days after surgery. Postoperative complications (peritonitis, impacti...
Invasive pulmonary aspergillosis of horses: an association with acute enteritis.
Veterinary pathology    July 1, 1988   Volume 25, Issue 4 277-281 doi: 10.1177/030098588802500405
Slocombe RF, Slauson DO.Invasive pulmonary aspergillosis was identified in 19 horses. In 16 cases mycotic lesions were associated with enterocolitis; 14 cases appeared to result from Salmonella infection. Pulmonary lesions included multifocal areas of acute necrosis, leukocytoclastic vasculitis, and thrombosis with fibrinosuppurative inflammation surrounding mycelial masses. Thromboemboli with fungi were in the brain and kidneys of three cases. Factors which appeared to predispose to pulmonary aspergillosis included corticosteroid therapy, disseminated neoplasms, hepatitis, pleuritis, and peritonitis. This study sugg...
Response of pony peritoneum to four peritoneal lavage solutions.
American journal of veterinary research    June 1, 1988   Volume 49, Issue 6 889-894 
Schneider RK, Meyer DJ, Embertson RM, Gentile DG, Buergelt CD.Peritoneal lavage was performed on ponies to determine the effect on peritoneal surfaces. Lavage solution (20 L) was introduced into each pony's peritoneal cavity through catheters placed in the paralumbar fossa, and the solution was removed by drainage from the ventral portion of the abdomen. Six ponies each were lavaged with sterile saline (0.9% NaCl) solution, sterile saline solution containing 5 X 10(6) U of potassium penicillin and 3 g of neomycin or povidone-iodine diluted to 3% by volume with sterile saline solution, and 3 ponies were lavaged with povidone-iodine diluted to 10% with ste...
Prevention and management of peritonitis in horses.
The Veterinary clinics of North America. Equine practice    April 1, 1988   Volume 4, Issue 1 145-156 doi: 10.1016/s0749-0739(17)30655-7
Markel MD.Peritonitis and adhesions in the horse are best managed through prevention. Perioperative antimicrobial therapy, nonsteroidal anti-inflammatory therapy, experienced personnel, and good surgical techniques should minimize complications after surgery. Despite preventative measures, some horses still develop peritonitis after surgery. Immediate, intensive treatment is necessary to enhance their chances for survival.
Recognition and management of ileus.
The Veterinary clinics of North America. Equine practice    April 1, 1988   Volume 4, Issue 1 91-104 doi: 10.1016/s0749-0739(17)30652-1
Adams SB.Ileus may occur in horses of all ages secondarily to drug administration, colic, exhaustion, peritonitis, or metabolic disorders. Ileus most commonly occurs following abdominal surgery for colic and is a significant cause of postoperative mortality in these horses. The most common clinical signs of ileus are decreased or absent intestinal sounds and gastric reflux. Ileus is treated by eliminating the initiating causes, correcting metabolic imbalances, decompressing distended bowel, providing analgesia, stimulating motility with drugs, and regulating exercise and feed and water intake.
Complications of umbilical hernias in horses: 13 cases (1972-1986).
Journal of the American Veterinary Medical Association    March 15, 1988   Volume 192, Issue 6 804-807 
Freeman DE, Orsini JA, Harrison IW, Muller NS, Leitch M.Of 147 horses treated for umbilical hernias over a 13.5-year period, 13 horses (8.8%) developed complications in association with umbilical defects. Six horses had intestinal incarceration; the incarceration was reduced manually in 3 horses before admission, resolved without treatment in 2 others, and was surgically reduced in one. Herniorrhaphy was performed on 4 of the 5 horses in which the incarceration did not require surgical reduction, and the fifth was managed conservatively. A horse with a parietal hernia and a horse with intestinal stragulation were treated surgically; in the latter, ...
Seminoperitoneum and peritonitis in a mare.
Equine veterinary journal    January 1, 1988   Volume 20, Issue 1 71-73 doi: 10.1111/j.2042-3306.1988.tb01460.x
Hinchcliff KW, MacWilliams PS, Wilson DG.No abstract available
Effects of castration on peritoneal fluid in the horse.
Journal of veterinary internal medicine    January 1, 1988   Volume 2, Issue 1 22-25 doi: 10.1111/j.1939-1676.1988.tb01973.x
Schumacher J, Schumacher J, Spano JS, McGuire J, Scrutchfield WL, Feldman RG.Twenty-four clinically normal horses were castrated by routine methods. Peritoneal fluid was collected prior to castration and at 1, 3, 5, and 7 days postcastration. Peritoneal fluid was collected on days 9 and 11 if nucleated cell (NC) counts were still markedly elevated on day 7. Peritonitis, defined as NC counts greater than 10,000/microliters, was evident in 15 horses following castration. Mean NC counts peaked on day 5 but were less than 10,000/microliters for 74% of the horses by day 7, and 90% of the horses by day 9. One horse had a NC count greater than 60,000/microliters on day 11 whe...
Use of clinical pathology in evaluation of horses with colic.
The Veterinary clinics of North America. Equine practice    December 1, 1987   Volume 3, Issue 3 529-542 doi: 10.1016/s0749-0739(17)30663-6
Parry BW.Clinical pathology is a valuable adjunct to physical examination of cases of colic. The present review considers evaluation of cases of colic for three main purposes: (1) making a prognosis, (2) deciding whether to operate, and (3) making a diagnosis. Blood tests noted to be useful for prognostication were hematocrit, lactate and urea nitrogen concentrations, pH, anion gap, fibrin/fibrinogen degradation products, antithrombin III activity, prothrombin time, and thrombin time. Horses with a poor prognosis often have relative polycythemia, marked lactic acidosis, high anion gap, azotemia, and co...
Temporary indwelling rectal liner for use in horses with rectal tears.
Journal of the American Veterinary Medical Association    September 15, 1987   Volume 191, Issue 6 677-680 
Taylor TS, Watkins JP, Schumacher J.A temporary indwelling liner was surgically installed in 17 horses with grade III or grade IV rectal tears. The rectal tears of 9 of the horses healed. The remaining 8 horses developed peritonitis as a result of peritoneal contamination before surgery, a change in grade of the tear, or material failure.