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Topic:Retrospective Study

Retrospective studies in horses involve the analysis of pre-existing data to identify patterns, outcomes, and associations related to health and disease within equine populations. These studies utilize historical records, such as veterinary medical histories, treatment outcomes, and diagnostic results, to explore various aspects of equine health and management. Retrospective studies can provide insights into the prevalence of diseases, the effectiveness of treatments, and risk factors associated with certain conditions. This page aggregates peer-reviewed research studies and scholarly articles that focus on the methodologies, findings, and implications of retrospective analyses in equine veterinary science.
Equine glaucoma: a histopathologic retrospective study (1999-2012).
Veterinary ophthalmology    July 16, 2013   Volume 17, Issue 5 334-342 doi: 10.1111/vop.12080
Curto EM, Gemensky-Metzler AJ, Chandler HL, Wilkie DA.To characterize and describe the histopathologic findings in equine globes enucleated due to glaucoma. Methods: Medical records at The Ohio State University from 1999 to 2012 were reviewed retrospectively. Signalment, history, and treatment data were collected, and histologic slides of enucleated globes were examined and lesions recorded. Twenty-three eyes from 23 horses were eligible for inclusion in this study. Results: The majority of affected horses were > 15 years of age (65%). The ages ranged from 5 to 35 years (mean = 17.4 years). The left eye was affected in 10 cases (43%) and the righ...
Equine herpesvirus 1 (EHV-1) nucleotide polymorphism determination using formalin fixed tissues in EHV-1 induced abortions and myelopathies with real-time PCR and pyrosequencing.
Journal of virological methods    July 11, 2013   Volume 193, Issue 2 371-373 doi: 10.1016/j.jviromet.2013.06.039
Tewari D, Del Piero F, Cieply S, Feria W, Acland H.Equine herpesvirus-1 (EHV-1) strains with a single point mutation at the 2254 nucleotide position with a G2254 constitution within the DNA polymerase gene are associated strongly with equine myeloencephalopathies. Infections with non-neuropathogenic EHV-1 strains without the G2254 nucleotide but with an A2254 nucleotide are associated less frequently with equine neurologic disease. A retrospective study utilizing DNA extracted from formalin fixed paraffin embedded tissues was conducted with real time PCR and pyrosequencing, to determine the infecting EHV-1 strains. Infection with EHV-1 A2254 a...
The influence of suture pattern on the incidence of incisional drainage following exploratory laparotomy.
Equine veterinary journal    July 8, 2013   Volume 46, Issue 2 156-160 doi: 10.1111/evj.12091
Colbath AC, Patipa L, Berghaus RD, Parks AH.Incisional complications following exploratory celiotomy increase morbidity, extend hospitalisation and increase cost. Retrospective studies seek to identify risk factors and measures for prevention of surgical site infection. The relatively high incidence of incisional complications following exploratory laparotomy necessitates identification of ideal surgical closure methods. Objective: The study sought to identify the incidence of incisional drainage within our hospital population, and to identify risk factors for incisional complications while determining surgical practices that reduce the...
Surveillance of equine influenza viruses through the RESPE network in France from November 2005 to October 2010.
Equine veterinary journal    July 8, 2013   Volume 45, Issue 6 776-783 doi: 10.1111/evj.12100
Legrand LJ, Pitel PH, Marcillaud-Pitel CJ, Cullinane AA, Couroucé AM, Fortier GD, Freymuth FL, Pronost SL.The Réseau d'Epidémio-Surveillance en Pathologie Equine (RESPE, the French epidemiological network for equine diseases) is a network for epidemio-surveillance of major equine diseases based around sentry veterinarians in France. Objective: The aim of this study was to evaluate the contribution of RESPE to efficient surveillance of equine influenza virus (EIV) in France. Methods: Retrospective cross-sectional study. Methods: From November 2005 to October 2010, epidemiological and phylogenetic studies were performed on 1426 nasopharyngeal swabs received at the Frank Duncombe Laboratory. Detect...
Fractures of the third trochanter in horses: 8 cases (2000-2012).
Journal of the American Veterinary Medical Association    July 5, 2013   Volume 243, Issue 2 261-266 doi: 10.2460/javma.243.2.261
Bertoni L, Seignour M, de Mira MC, Coudry V, Audigie F, Denoix JM.To determine history; clinical, radiographic, ultrasonographic, and scintigraphic features; management; and outcome associated with third trochanter fractures in horses. Methods: Retrospective case series. Methods: 8 horses. Methods: Records from 2000 to 2012 were reviewed, and signalment, case history, severity and duration of lameness, results of physical and lameness examinations, imaging findings, management, and outcome were evaluated. Results: All horses had a history of acute onset of severe lameness. Four of the 8 horses had localizing physical signs of fracture. No specific gait chara...
Radiographic configuration and healing of 121 fractures of the proximal phalanx in 120 Thoroughbred racehorses (2007-2011).
Equine veterinary journal    July 4, 2013   Volume 46, Issue 1 81-87 doi: 10.1111/evj.12094
Smith MR, Wright IM.Although fractures of the proximal phalanx are one of the most common long bone fractures of Thoroughbred horses in training, limited details on variations in morphology and radiological progression have been published. Objective: To describe in detail the configuration of parasagittal fractures of the proximal phalanx in a group of Thoroughbred racehorses, to report fracture distribution within this group of horses and to document radiological progression of fracture healing in cases treated by internal fixation. Methods: Restrospective case series. Methods: Case records and radiographs of Th...
Are there radiologically identifiable prodromal changes in Thoroughbred racehorses with parasagittal fractures of the proximal phalanx?
Equine veterinary journal    July 4, 2013   Volume 46, Issue 1 88-91 doi: 10.1111/evj.12093
Smith MR, Wright IM.Fractures of the proximal phalanx are generally considered to result from monotonic supraphysiological loads, but radiological observations from clinical cases suggest there may be a stress-related aetiology. Objective: To determine whether there are radiologically identifiable prodromal changes in Thoroughbred racehorses with confirmed parasagittal fractures of the proximal phalanx. Methods: Retrospective cross-sectional study. Methods: Case records and radiographs of Thoroughbred racehorses with parasagittal fractures of the proximal phalanx were analysed. Thickness of the subchondral bone p...
Development of a real-time PCR to detect Streptococcus equi subspecies equi.
Equine veterinary journal    June 28, 2013   Volume 46, Issue 1 56-59 doi: 10.1111/evj.12088
North SE, Wakeley PR, Mayo N, Mayers J, Sawyer J.Infection with Streptococcus equi subspecies equi (S. equi) is endemic in the UK. A proportion of horses serve as long-term carriers and act as a reservoir of infection. Detection of these persistently infected horses is difficult using standard culture techniques owing to a lack of sensitivity and overgrowth by contaminating bacteria. In addition, differentiation of this causative bacterium from the closely related S. equi zooepidemicus has made the development of reliable and accurate diagnostic tests difficult. Objective: To develop and validate a sensitive and specific real-time PCR assay ...
Equine grass sickness in Scotland: a case-control study of signalment- and meteorology-related risk factors.
Equine veterinary journal    June 28, 2013   Volume 46, Issue 1 64-71 doi: 10.1111/evj.12077
Wylie CE, Shaw DJ, Fordyce FM, Lilly A, McGorum BC.Equine grass sickness (EGS) remains a frequently fatal disease of equids in Britain. Since previous investigations of signalment- and meteorology-related risk factors for EGS have yielded some conflicting data, further investigation is warranted. Objective: To identify signalment- and meteorology-related risk factors for EGS in Scotland. Methods: Retrospective time-matched case-control study. Methods: This study was undertaken using data for 455 EGS cases and 910 time-matched controls that were referred to the Royal (Dick) School of Veterinary Studies, and average UK Meteorological Office weat...
Intramodality and intermodality agreement in radiography and computed tomography of equine distal limb fractures.
Equine veterinary journal    June 28, 2013   Volume 46, Issue 1 92-96 doi: 10.1111/evj.12082
Crijns CP, Martens A, Bergman HJ, van der Veen H, Duchateau L, van Bree HJ, Gielen IM.Computed tomography (CT) is increasingly accessible in equine referral hospitals. Objective: To document the level of agreement within and between radiography and CT in characterising equine distal limb fractures. Methods: Retrospective descriptive study. Methods: Images from horses that underwent radiographic and CT evaluation for suspected distal limb fractures were reviewed, including 27 horses and 3 negative controls. Using Cohen's kappa and weighted kappa analysis, the level of agreement among 4 observers for a predefined set of diagnostic characteristics for radiography and CT separately...
A long-term study on the clinical effects of mechanical widening of cheek teeth diastemata for treatment of periodontitis in 202 horses (2008-2011).
Equine veterinary journal    June 28, 2013   Volume 46, Issue 1 76-80 doi: 10.1111/evj.12085
Dixon PM, Ceen S, Barnett T, O'Leary JM, Parkin TD, Barakzai S.Cheek teeth diastemata are a common cause of painful periodontal disease in horses, but there is limited objective information on their treatment. Objective: To assess the long-term response to diastema widening in clinically affected horses. Methods: Retrospective study. Methods: Medical records from cases of cheek teeth diastemata treated by diastema widening referred to the University of Edinburgh Equine Hospital from 2008 to 2011 were analysed. Results: During this period, 302 horses were diagnosed with clinically significant cheek teeth diastemata, of which 202, median age 11 years, with ...
Hospitalization due to horse-related injuries: has anything changed? A 25 year survey.
The Israel Medical Association journal : IMAJ    June 21, 2013   Volume 15, Issue 4 169-172 
Abu-Kishk I, Klin B, Gilady-Doron N, Jeroukhimov I, Eshel G.Horse riding and horse handling are dangerous. There is a lack of knowledge concerning the incidence of hospitalization due to horse-related injuries and types of injuries in Israel. During the last two decades we have observed an increasing incidence of hospitalizations due to horse-related injuries at our medical center as well as the frequent involvement of pediatric patients. Objective: To investigate these injuries with respect to type, incidence and modes of prevention. Methods: We conducted a retrospective study of medical records for all patients admitted to Assaf Harofeh Medical Cente...
Risk of septic arthritis after intra-articular medication: a study of 16,624 injections in Thoroughbred racehorses.
Australian veterinary journal    June 21, 2013   Volume 91, Issue 7 268-273 doi: 10.1111/avj.12073
Steel CM, Pannirselvam RR, Anderson GA.The aims of this study were to determine the risk of septic arthritis after intra-articular medication (IAM) and to identify potential risk factors for this complication. Methods: A retrospective and prospective descriptive study of prevalence, and matched case-control study for risk factors. Results: Of 16,624 joints injected in 1103 horses at 6695 horse-visits, septic arthritis occurred as a complication in 13 joints (13 horses). The risk of septic arthritis following IAM was 7.8 cases per 10,000 injections or 1 case per 1279 injections. Veterinarian and type of corticosteroid were identifie...
Eosinophilic keratitis in 46 eyes of 27 horses in the Mid-Atlantic United States (2008-2012).
Veterinary ophthalmology    June 14, 2013   Volume 17, Issue 5 311-320 doi: 10.1111/vop.12076
Lassaline-Utter M, Miller C, Wotman KL.To review the signalment, clinical characteristics, treatment, and outcome of equine EK cases in the Mid-Atlantic United States; to evaluate the effects of topical or systemic corticosteroid treatment, oral cetirizine treatment and secondary corneal infection on disease duration; and to evaluate the association between corticosteroid and cetirizine treatment and likelihood of recurrence. Methods: Twenty-seven horses (47 eyes) diagnosed with EK from 2008 to 2012. Methods: Retrospective medical record review followed by phone interview to obtain recurrence data. Results: Average age of affected ...
Preliminary genetic analyses of important musculoskeletal conditions of Thoroughbred racehorses in Hong Kong.
Veterinary journal (London, England : 1997)    June 5, 2013   Volume 198, Issue 3 611-615 doi: 10.1016/j.tvjl.2013.05.002
Welsh CE, Lewis TW, Blott SC, Mellor DJ, Lam KH, Stewart BD, Parkin TD.A retrospective cohort study of important musculoskeletal conditions of Thoroughbred racehorses was conducted using health records generated over a 15 year period (n=5062, 1296 sires). The prevalence of each condition in the study population was: fracture, 13%; osteoarthritis, 10%; suspensory ligament injury, 10%; and tendon injury, 19%. Linear and logistic sire and animal regression models were built to describe the binary occurrence of these musculoskeletal conditions, and to evaluate the significance of possible environmental risk factors. The heritability of each condition was estimated us...
Effect of displaced versus non-displaced pelvic fractures on long-term racing performance in 31 Thoroughbred racehorses.
Australian veterinary journal    April 26, 2013   Volume 91, Issue 6 246-250 doi: 10.1111/avj.12053
Hennessy SE, Muurlink MA, Anderson GA, Puksmann TN, Whitton RC.To evaluate the long-term racing prognosis for Thoroughbred racehorses with displaced versus non-displaced fractures of the pelvis identified by scintigraphy. Methods: Retrospective case analysis. Methods: Medical records of 31 Thoroughbred racehorses presenting to the University of Melbourne Equine Centre with fractures of the pelvis that were identified by scintigraphy were reviewed. Pelvic fracture site was determined and defined as displaced or non-displaced based on ultrasound and/or radiographic findings. Race records were analysed for each horse, with a minimum of 24 months' follow-up, ...
Epistaxis in racehorses: risk factors and effects on career.
Australian veterinary journal    April 26, 2013   Volume 91, Issue 5 198-203 doi: 10.1111/avj.12049
Langford JL, Thomson PC, Knight PK.To profile Thoroughbreds that incurred a ban under Australian Rule of Racing 53A on New South Wales racetracks between August 1999 and July 2008, determine the effect on their careers and identify the factors that predict whether these horses would race again or experience a recurrence of epistaxis. Methods: Differences between horses that did or did not return to racing and did or did not suffer recurrent epistaxis were determined. Backwards stepwise logistic regression was used to identify variables predicting a return to racing and recurrence of epistaxis. Results: The mean (± SD) age at t...
Factors affecting live foal rates of Thoroughbred mares that undergo manual twin elimination.
Equine veterinary journal    April 24, 2013   Volume 45, Issue 6 676-680 doi: 10.1111/evj.12074
Schnobrich MR, Riddle WT, Stromberg AJ, LeBlanc MM.Mares diagnosed with twin vesicles at 13-17 days after ovulation commonly have one of 2 vesicles manually reduced. It is not known whether vesicle location (adjacent vs. nonadjacent), mare age, mare reproductive status, parity, month of breeding or mare plasma progesterone concentration affects live foal rates. Objective: To determine factors associated with a positive outcome (live foal) in mares undergoing manual twin reduction between 13 and 17 days post ovulation when performed by a single operator. Methods: Retrospective case-control study. Methods: Breeding records and the Jockey Club re...
Risk factors associated with nasopharyngeal cicatrix syndrome in horses.
Journal of the American Veterinary Medical Association    April 23, 2013   Volume 242, Issue 9 1267-1270 doi: 10.2460/javma.242.9.1267
Norman TE, Chaffin MK, Bissett WT, Thompson JA.To determine risk factors associated with the development of nasopharyngeal cicatrix syndrome (NCS) in horses. Methods: Retrospective case-control study. Methods: 242 horses referred for endoscopic evaluation of the upper portion of the respiratory tract (121 horses with NCS and 121 control horses). Methods: Medical records of horses that had an endoscopic evaluation of the upper airway performed between January 2003 and December 2008 were reviewed. Signalment, housing management, and season of evaluation were recorded and reviewed for each horse. The associations between clinical signs and en...
Injuries associated with recreational horse riding and changes over the last 20 years: a review.
JRSM short reports    April 22, 2013   Volume 4, Issue 5 2042533313476688 doi: 10.1177/2042533313476688
Sandiford N, Buckle C, Alao U, Davidson J, Ritchie J.To assess the incidence and distribution of recreational equestrian injuries seen in the Kent and Sussex region and review the available literature on this subject. Methods: This is a retrospective case series with historical controls. Methods: Kent and Sussex region, England. Methods: Injuries related to horses in the recreational setting. Methods: Subjects were selected from our acute injury database. Notes of all patients presenting with horse riding-related injuries between January and December 2010 were reviewed. Skeletal injuries were confirmed using our Picture Archiving and Communicati...
Descriptive epidemiology and risk factors for eliminations from Fédération Equestre Internationale endurance rides due to lameness and metabolic reasons (2008-2011).
Equine veterinary journal    April 9, 2013   Volume 46, Issue 1 38-44 doi: 10.1111/evj.12069
Nagy A, Murray JK, Dyson SJ.There is limited information on international endurance rides and on risk factors for eliminations. Objective: To describe and compare the frequency of occurrence of elimination due to lameness and metabolic reasons from Fédération Equestre Internationale (FEI) endurance rides (≥100 km) during 2008-2011 in all countries and to assess risk factors for elimination due to lameness and metabolic reasons. Methods: Retrospective unmatched case-control study. Methods: Data collected from the FEI website included the following: the country where the ride was held; the year; the result for each hor...
Clinical and diagnostic features of inflammatory airway disease subtypes in horses examined because of poor performance: 98 cases (2004-2010).
Journal of the American Veterinary Medical Association    April 4, 2013   Volume 242, Issue 8 1138-1145 doi: 10.2460/javma.242.8.1138
Nolen-Walston RD, Harris M, Agnew ME, Martin BB, Reef VB, Boston RC, Davidson EJ.To determine whether there are important differences relating to seasonality of signs or clinical features between subtypes of inflammatory airway disease (IAD) in horses caused by neutrophilic and eosinophilic-mastocytic inflammation having dissimilar etiopathologic pathways. Methods: Retrospective case series. Methods: 98 horses. Methods: Data were compiled from medical records of horses examined because of poor performance from 2004 through 2010. Horses underwent a standardized high-speed treadmill test, lameness evaluation, cardiac evaluation, and postexercise bronchoalveolar lavage (BAL)....
Comparison of phenylephrine administration and exercise versus phenylephrine administration and a rolling procedure for the correction of nephrosplenic entrapment of the large colon in horses: 88 cases (2004-2010).
Journal of the American Veterinary Medical Association    April 4, 2013   Volume 242, Issue 8 1146-1151 doi: 10.2460/javma.242.8.1146
Fultz LE, Peloso JG, Giguère S, Adams AR.To compare the outcome of horses with nephrosplenic entrapment of the large colon (NSELC) that were treated nonsurgically by IV administration of phenylephrine and exercise with that of horses treated by IV administration of phenylephrine and a rolling procedure under general anesthesia. Methods: Retrospective case series. Methods: 88 horses with NSELC. Methods: Horses examined between 2004 and 2010 because of acute abdominal pain that had NSELC on the basis of findings on abdominal palpation per rectum, abdominal ultrasonography, or both were included. Medical records were reviewed to obtain ...
Physicochemical interpretation of acid-base abnormalities in 54 adult horses with acute severe colitis and diarrhea.
Journal of veterinary internal medicine    April 3, 2013   Volume 27, Issue 3 548-553 doi: 10.1111/jvim.12071
Gomez DE, Arroyo LG, Stämpfli HR, Cruz LE, Oliver OJ.The quantitative effect of strong electrolytes, pCO2 , and plasma protein concentration in determining plasma pH and bicarbonate concentrations can be demonstrated with the physicochemical approach. Plasma anion gap (AG) and strong ion gap (SIG) are used to assess the presence or absence of unmeasured anions. Objective: The physicochemical approach is useful for detection and explanation of acid-base disorders in horses with colitis. AG and SIG accurately predict hyperlactatemia in horses with colitis. Methods: Fifty-four horses with acute colitis and diarrhea. Methods: Retrospective study. Ph...
Uterine bacterial isolates from mares and their resistance to antimicrobials: 8,296 cases (2003-2008).
Journal of the American Veterinary Medical Association    March 23, 2013   Volume 242, Issue 7 977-983 doi: 10.2460/javma.242.7.977
Davis HA, Stanton MB, Thungrat K, Boothe DM.To describe bacteria isolated from reproductive tracts of mares and to examine the extent and patterns of resistance to antimicrobials commonly used for treatment of endometritis. Methods: Retrospective case series. Methods: 8,296 uterine swab, lavage, or biopsy samples obtained between January 2003 and December 2008 from 7,665 horses in central Florida. Methods: Results of bacterial culture and antimicrobial susceptibility testing were obtained for uterine swab, lavage, and biopsy samples collected from mares undergoing a routine breeding examination or examined because of a reproductive diso...
Prevalence of abnormal radiographic findings in 2-year-old Thoroughbreds at in-training sales and associations with racing performance.
Journal of the American Veterinary Medical Association    March 23, 2013   Volume 242, Issue 7 969-976 doi: 10.2460/javma.242.7.969
Meagher DM, Bromberek JL, Meagher DT, Gardner IA, Puchalski SM, Stover SM.To estimate the prevalence of radiographic abnormalities (lesions) in Thoroughbred racehorses at 2-year-old in-training sales and determine whether these lesions and 1-furlong presale workout times were associated with subsequent racing performance. Methods: Retrospective cohort study. Methods: 953 Thoroughbreds. Methods: Repository radiographs of carpal, metacarpophalangeal and metatarsophalangeal (fetlock), stifle, and tarsal (hock) joints were examined. Horses with lesions were classified by lesion type and location. Race performance variables were compared between horses with and without l...
Fragmentation of the proximal tubercle of the talus in horses: 9 cases (2004-2010).
Journal of the American Veterinary Medical Association    March 23, 2013   Volume 242, Issue 7 984-991 doi: 10.2460/javma.242.7.984
Espinosa P, Lacourt M, Alexander K, David F, Laverty S.To identify the prevalence of fragmentation of the proximal tubercle of the talus (FPTT) in a hospital population of horses, characterize the anatomic features of the affected area and fragments, and describe clinical findings, diagnosis, treatment, and outcome for horses with FPTT. Methods: Retrospective case series. Methods: 9 horses with FPTT. Methods: 2,543 radiographic views of the tarsal region of 1,526 horses that were evaluated between June 2004 and December 2010 were reviewed. Medical case records for horses with detectable FPTT were retrieved, and signalment, history, clinical signs,...
A cohort study of equine laminitis in Great Britain 2009-2011: estimation of disease frequency and description of clinical signs in 577 cases.
Equine veterinary journal    March 12, 2013   Volume 45, Issue 6 681-687 doi: 10.1111/evj.12047
Wylie CE, Collins SN, Verheyen KL, Newton JR.A previous systematic review highlighted a lack of good evidence regarding the frequency of equine laminitis in Great Britain. Objective: To estimate the frequency of veterinary-diagnosed active laminitis in the general horse population of Great Britain and to describe the clinical signs present in cases. Methods: Prospective cohort study. Methods: Data on active episodes of equine laminitis were collected from veterinary practitioners. Results: The prevalence of veterinary-diagnosed active laminitis was 0.47% (95% confidence interval [CI] 0.42-0.52%) for the veterinary-attended population and...
Equine keratomycosis in Switzerland: a retrospective evaluation of 35 horses (January 2000-August 2011).
Equine veterinary journal    March 12, 2013   Volume 45, Issue 5 608-612 doi: 10.1111/evj.12042
Voelter-Ratson K, Pot SA, Florin M, Spiess BM.Keratomycosis is a severe disease in horses. Geographical differences in fungi causing keratomycosis and susceptibility of the organisms to antifungal drugs exist but few previous publications on this disease originate from Europe. Objective: To retrospectively compare the clinical data of 36 eyes with keratomycosis, diagnosed in 35 horses between January 2000 and August 2011 at the Vetsuisse Faculty of Switzerland. Case history, season, prior treatment, clinical appearance, surgical and medical treatment, treatment duration, and globe survival were evaluated. Methods: Retrospective case serie...
A retrospective look at students enrolled in an upper-level horse science class: factors that affect classroom performance.
Journal of animal science    March 11, 2013   Volume 91, Issue 6 2976-2984 doi: 10.2527/jas.2012-5936
Douthit TL, Bormann JM, Kouba JM.The objective of this study was to retrospectively analyze demographic variables and academic preparation of students to determine how these factors relate to student performance in ASI 521 Horse Science, an upper-level course offered in the Department of Animal Sciences and Industry (ASI) at Kansas State University (KSU). Data were collected for 264 students enrolled in the course from 2008 to 2010. Students who took the course in 2008 received greater final percentages than those who took the course in subsequent years (P = 0.0016). Females tended to receive greater percentages than males (P...
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