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Topic:Thoroughbreds

Thoroughbreds are a breed of horse known for their agility, speed, and spirit, often associated with horse racing and equestrian sports. Originating from crossbreeding native English mares with imported Arabian, Barb, and Turkoman stallions, Thoroughbreds have a well-documented pedigree that traces back to the late 17th and early 18th centuries. This breed is characterized by a refined head, deep chest, and long legs, contributing to their athletic capabilities. Thoroughbreds are primarily bred for their performance in racing but are also utilized in other equestrian disciplines. This page compiles peer-reviewed research studies and scholarly articles that explore the genetics, physiology, and performance characteristics of Thoroughbreds, as well as their management and welfare in various equine activities.
Clinical significance of aerobic bacterial flora of the uterus, vagina, vestibule, and clitoral fossa of clinically normal mares.
Journal of the American Veterinary Medical Association    July 1, 1988   Volume 193, Issue 1 72-75 
Hinrichs K, Cummings MR, Sertich PL, Kenney RM.Swab specimens for bacterial culture were obtained from the uterus, vagina, vestibule, and clitoral fossa of 48 mares that had normal reproductive tracts, no history of reproductive problems, and no inflammation on evaluation of endometrial biopsy. The mares were predominantly Thoroughbred and Standardbred. Swab specimens of the vagina were obtained through a sterile speculum; swab specimens of the uterus were obtained by use of a double-guarded, occluded culture instrument. Fifteen (31%) of the uterine swab specimens and 20 (42%) of the vaginal swab specimens yielded growth on aerobic culture...
Effect of third carpal slab fracture and repair on racing performance in Thoroughbred horses: 31 cases (1977-1984).
Journal of the American Veterinary Medical Association    July 1, 1988   Volume 193, Issue 1 107-110 
Martin GS, Haynes PF, McClure JR.Between 1977 and 1984, 31 Thoroughbred horses (mean age, 2.8 years) were surgically treated for slab fractures of the third carpal bone. All fractures involved the articular surfaces of the intercarpal and the carpometacarpal joints in a frontal plane and had a cuboidal or slab shape. In 20 of the horses, the bone was fractured during racing and in 8 of the horses, the bone was fractured during race training. The right limb was affected more frequently than was the left limb (24 vs 7, P less than 0.05). Twenty-one (67.6%) horses raced at least once after recovery from the surgery. Data were av...
Long-acting antibiotic preparations in racehorses.
The Veterinary record    June 25, 1988   Volume 122, Issue 26 639 doi: 10.1136/vr.122.26.639-a
Abraham BF, Singleton WB.No abstract available
Objective assessment of detomidine-induced analgesia and sedation in the horse.
European journal of pharmacology    June 22, 1988   Volume 151, Issue 1 1-8 doi: 10.1016/0014-2999(88)90685-1
Kamerling SG, Cravens WM, Bagwell CA.The effects of detomidine, a veterinary sedative analgesic, were studied in the horse. Novel objective techniques were employed to assess the analgesic and sedative potency of this compound. Intravenous doses of 0.010, 0.020 and 0.040 mg/kg were administered to eight adult Thoroughbred racehorses according to a double-blind crossover design. Analgesia was measured by determining the latency to onset of the skin twitch and hoof withdrawal reflexes following noxious thermal stimulation of the withers and fetlock, respectively. Sedation was assessed by quantifying spontaneous locomotor activity i...
Propagation of a dorsal cortical fracture of the third metacarpal bone in two horses.
Journal of the American Veterinary Medical Association    June 1, 1988   Volume 192, Issue 11 1587-1589 
Spurlock GH.Seemingly, propagation of a dorsal cortical fracture in the third metacarpal bone developed after continued race performance in 2 horses. Historically, both horses had intermittent lameness that had responded to nonsteroidal anti-inflammatory drugs and brief rest periods. However, lameness in both horses had increased in severity. Radiography revealed a dorsal cortical fracture of the third metacarpal bone, with propagation of the fracture plane proximally. Fractures were incomplete and healed with stall rest in both horses.
Endotoxaemia in racehorses following exertion.
Journal of the South African Veterinary Association    June 1, 1988   Volume 59, Issue 2 63-66 
Baker B, Gaffin SL, Wells M, Wessels BC, Brock-Utne JG.Endotoxins (lipopolysaccharides-LPS) and anti-endotoxin IgG antibodies were measured in racehorses before and after races of 1,000, 2,000 and 2,800 m. Results show that the mean plasma concentration of endotoxin increased significantly (p less than 0.02) while the anti-LPS IgG concentration decreased significantly (p less than 0.005) in all horses following the races. Pre-race and post-race anti-LPS IgG levels in racing-fit racehorses were significantly higher than in untrained horses (p less than 0.05). The possibility therefore exists that training-induced stress leads to leakage of LPS into...
Use of lag screw fixation for repair of a central tarsal bone fracture in a horse.
Journal of the American Veterinary Medical Association    May 15, 1988   Volume 192, Issue 10 1451-1452 
Ramey DW.An 8-year-old Thoroughbred gelding was determined to have a sagittal fracture of the central tarsal bone. Lag screw fixation of the fracture enabled the horse to return to jumping, although degenerative arthritis of the distal intertarsal joint was apparent radiographically 17 months after the injury.
Estimation of genetic trend in racing performance of thoroughbred horses.
Nature    April 21, 1988   Volume 332, Issue 6166 722-724 doi: 10.1038/332722a0
Gaffney B, Cunningham EP.Thoroughbred horses have been bred exclusively for racing in England since Tudor times and thoroughbred horse racing is now practised in over 40 countries and involves more than half-a-million horses worldwide. The genetic origins of the thoroughbred go back largely to horses imported from the Middle East and North Africa to England in the late seventeenth and early eighteenth centuries. Since the establishment of the Stud Book in 1791, the population has been effectively closed to outside sources, and over 80% of the thoroughbred population's gene pool derives from 31 known ancestors from thi...
Consolidating pneumonia and pneumothorax in a horse.
Journal of the American Veterinary Medical Association    April 15, 1988   Volume 192, Issue 8 1081-1082 
Spurlock SL, Spurlock GH, Donaldson LL.A 3-year-old Thoroughbred mare with signs of acute abdominal pain and chronic pneumonia was found to have pneumothorax. A single application of suction was successful in resolving the pneumothorax. The underlying pneumonia was treated with long-term antibiotic administration selected on the basis of results of bacteriologic culture and antimicrobial susceptibility testing of a transtracheal aspirate. The pneumonia resolved, and the mare returned to competition as a show hunter.
Relationships between the erythrocyte sedimentation rate, plasma proteins and viscosity, and leucocyte counts in thoroughbred racehorses.
The Veterinary record    April 2, 1988   Volume 122, Issue 14 329-332 doi: 10.1136/vr.122.14.329
Allen BV.The influence of plasma proteins on erythrocyte aggregation was studied in a population of young thoroughbred racehorses, using the 60 minute erythrocyte sedimentation rate (ESR) with and without haematocrit standardisation. The ESR was correlated inversely with the haematocrit, but directly with fibrinogen, plasma viscosity and serum total globulins. When ESR values were standardised to a common haematocrit the correlation coefficients for the same plasma protein factors were increased. Albumin levels showed a strong direct relationship with haematocrit which accounted for the inverse correla...
Fractures in Thoroughbred race horses.
The Cornell veterinarian    April 1, 1988   Volume 78, Issue 2 1-133 
Krook L, Maylin GA.No abstract available
Buphthalmos in a Thoroughbred foal.
Equine veterinary journal    March 1, 1988   Volume 20, Issue 2 132-135 doi: 10.1111/j.2042-3306.1988.tb01477.x
Barnett KC, Cottrell BD, Paterson BW, Ricketts SW.No abstract available
The effects of high intensity exercise on the plasma concentration of lactate, potassium and other electrolytes.
Equine veterinary journal    March 1, 1988   Volume 20, Issue 2 109-113 doi: 10.1111/j.2042-3306.1988.tb01470.x
Harris P, Snow DH.To study the effect of short term high intensity exercise on plasma lactate, potassium, sodium and chloride concentrations, five Thoroughbred horses were galloped on a treadmill at a 5 degree incline. Following a standardised warm-up period, they were galloped at 8, 10, or 12 metres/sec for 2 mins. One horse also galloped at 14 metres/sec for 1.5 mins. Sequential arterial and/or venous blood samples were collected during exercise and recovery. At 12 metres/sec, the effect of different recovery modes, ie, standing, walking or trotting, on the electrolytes was also examined. There was a progress...
Management of arytenoid chondropathy and failed laryngoplasty in horses: 75 cases (1979-1985).
Journal of the American Veterinary Medical Association    March 1, 1988   Volume 192, Issue 5 670-675 
Tulleners EP, Harrison IW, Raker CW.By use of endoscopy, 75 horses with respiratory noise and/or exercise intolerance were determined to have structural arytenoid cartilage abnormalities (60 primary, 11 after previous laryngeal surgery), or failed left laryngoplasty (4 horses) for laryngeal hemiplegia in which the arytenoid cartilage still appeared normal. Eighty-eight percent of the horses were either Thoroughbred (54 horses; 72%) or Standardbred (12 horses; 16%) racehorses; only 9 horses (12%) had occupations not related to racing. Seventy-six percent of the racehorses were 2 to 4 years old; all non-racehorses were greater tha...
Sudden and unexpected death in horses and ponies: an analysis of 200 cases.
Equine veterinary journal    March 1, 1988   Volume 20, Issue 2 99-103 doi: 10.1111/j.2042-3306.1988.tb01468.x
Brown CM, Kaneene JB, Taylor RF.An analysis was made of the causes of death in horses and ponies over one year of age which died suddenly (Group 1) or were found dead but were considered normal when last seen (Group 2). There were 49 animals in Group 1. Thoroughbreds were overrepresented, but there were no ponies in this group. No cause of death was found in 30.6 per cent of cases and 16.3 per cent died from each of the following causes: haemorrhage in the respiratory system, central nervous system, and adverse drug reactions. Cardiovascular lesions were the cause of death in 14.4 per cent and the remaining 3.1 per cent had ...
Cardiovascular and respiratory responses to submaximal exercise training in the thoroughbred horse.
Pflugers Archiv : European journal of physiology    March 1, 1988   Volume 411, Issue 3 316-321 doi: 10.1007/BF00585121
Evans DL, Rose RJ.Cardiovascular and respiratory responses to submaximal exercise training were investigated in 6 thoroughbred racehorses. Oxygen uptake, heart rate (HR) and arteriovenous oxygen content difference were measured during incremental treadmill exercise tests, before and after 7 weeks of treadmill training. Cardiac output during exercise was calculated by the direct Fick technique. Maximal oxygen uptake (VO2max) was increased by 23% after training, from 129.7 ml/kg/min to 160.0 ml/kg/min. The treadmill speed at which VO2max was attained increased by 19%. The increased aerobic power after training wa...
Near drowning of a gelding.
Journal of the American Veterinary Medical Association    February 1, 1988   Volume 192, Issue 3 377-378 
Humber KA.After becoming entangled in safety lines and being submerged in a chlorinated swimming pool, a 2-year-old Thoroughbred gelding was evaluated and treated successfully. Treatment included antimicrobial agents, anti-inflammatory drugs, bronchodilators, diuretics, humidified oxygen, and surfactant transplant. The results of follow-up examination of the gelding 120 days after hospitalization were normal.
Scintigraphic appearance of stress-induced trauma of the dorsal cortex of the third metacarpal bone in racing Thoroughbred horses: 121 cases (1978-1986).
Journal of the American Veterinary Medical Association    February 1, 1988   Volume 192, Issue 3 390-395 
Koblik PD, Hornof WJ, Seeherman HJ.Review of 121 bone scintigrams obtained on racing Thoroughbred horses with clinical histories indicative of forelimb lameness revealed 3 scintigraphic patterns of stress-induced trauma to the dorsal cortex of the third metacarpal bone: (1) focal, intense uptake associated with recent stress fracture; (2) regional uptake of varying intensity or a mixed pattern of uptake associated with chronic stress fracture; and (3) diffuse, mild to moderate uptake associated with periostitis (bucked shins). The latter scintigraphic pattern appeared to be an exaggerated manifestation of the normal remodeling ...
Maximum O2 uptake, O2 debt and deficit, and muscle metabolites in Thoroughbred horses.
Journal of applied physiology (Bethesda, Md. : 1985)    February 1, 1988   Volume 64, Issue 2 781-788 doi: 10.1152/jappl.1988.64.2.781
Rose RJ, Hodgson DR, Kelso TB, McCutcheon LJ, Reid TA, Bayly WM, Gollnick PD.This study determined maximal O2 uptake (VO2max), maximal O2 deficit, and O2 debt in the Thoroughbred racehorse exercising on an inclined treadmill. In eight horses the O2 uptake (VO2) vs. speed relationship was linear until 10 m/s and VO2max values ranged from 131 to 153 ml.kg-1.min-1. Six of these horses then exercised at 120% of their VO2max until exhaustion. VO2, CO2 production (VCO2), and plasma lactate (La) were measured before and during exercise and through 60 min of recovery. Muscle biopsies were collected before and at 0.25, 0.5, 1, 1.5, 2, 5, 10, 15, 20, 40, and 60 min after exercis...
Small colon intussusception in a broodmare.
Journal of the American Veterinary Medical Association    February 1, 1988   Volume 192, Issue 3 372-374 
Ross MW, Stephens PR, Reimer JM.A 9-year-old pregnant Standardbred broodmare was evaluated for signs of mild abdominal pain, failure to defecate, and mild abdominal distention. Rectal examination revealed the leading edge of a small colon intussusception, and peritoneal fluid analysis indicated suppurative peritonitis. Surgical management, including reduction of the intussusception and small colon resection with end-to-end anastomosis, resulted in successful outcome (1-year follow-up evaluation). Postoperative complications including dehiscence of the ventral midline surgical incision and simple obstruction at the anastomosi...
Epidemiological studies of musculoskeletal racing and training injuries in Thoroughbred horses, Minnesota, U.S.A.
Acta veterinaria Scandinavica. Supplementum    January 1, 1988   Volume 84 340-343 
Robinson RA, Kobluk C, Clanton C, Martin F, Gordon B, Ames T, Trent M, Ruth G.No abstract available
Cortisol concentrations in blood and urine of horses.
Australian veterinary journal    January 1, 1988   Volume 65, Issue 1 1-5 doi: 10.1111/j.1751-0813.1988.tb14919.x
Ralston JM, Stenhouse AM, Stenhouse NS, Buck GJ, Lucks SF, Reynoldson JA, Bolton JR.A survey of the concentrations of cortisol in blood and urine samples taken from thoroughbred and standardbred horses after racing is presented. Statistical analysis showed the only significant difference between thoroughbred and standardbred horses was a higher cortisol concentration in thoroughbred urine. Urine volume and pH had no significant influence on the urinary cortisol concentration, however 9.5% of the urinary cortisol variation could be explained due to the influence of plasma cortisol concentration. The results of cortisol and ACTH administrations are also shown and compared with ...
The effect of oral L-carnitine supplementation on the muscle and plasma concentrations in the Thoroughbred horse.
Comparative biochemistry and physiology. A, Comparative physiology    January 1, 1988   Volume 91, Issue 4 827-835 doi: 10.1016/0300-9629(88)90971-1
Foster CV, Harris RC, Snow DH.1. L-carnitine was administered orally to thoroughbred horses for 58 days. 2. Acceptability and effects on plasma, muscle and urine concentration were studied. 3. Ten-60 g/day (as 2-3 doses) was acceptable with no deleterious effects. 4. One x 10 g L-carnitine significantly raised the plasma-free carnitine concentration (7 hr post) from 21.2 to 31.8 mumol/l; 2 x 30 g increased the mean to 36.5 mumol/l. 5. Plasma acetylcarnitine increased from approximately 1 to 5.5 mumol/l (7 hr post) on 2 x 30 g/day. 6. Muscle total carnitine was unchanged over 58 days. 7. Urinary output accounted for 3.5-7.5...
Subdivision of equine Tf into H1 and H2.
Animal genetics    January 1, 1988   Volume 19, Issue 2 177-183 doi: 10.1111/j.1365-2052.1988.tb00803.x
Bell K, Pollitt CC, Patterson SD.Subdivision of equine TfH into two variants, designated H1 (faster) and H2 (slower), has been accomplished by high voltage, thin layer polyacrylamide gel electrophoresis at pH 7.9. Transferrin H1 and H2 have been shown to be controlled by codominant alleles and gene frequencies of the Tf alleles have been determined in the Australian Thoroughbred, Standardbred. Quarter Horse and Arabian Horse breeds.
Association of arytenoid chondritis with equine lymphocyte antigens but no association with laryngeal hemiplegia, umbilical hernias and cryptorchidism.
Animal genetics    January 1, 1988   Volume 19, Issue 4 427-433 doi: 10.1111/j.1365-2052.1988.tb00834.x
McClure JJ, Koch C, Powell M, McClure JR.Associations were sought between ELA A1-A10 and W11 antigens and the presence of laryngeal hemiplegia, arytenoid chondritis, umbilical hernias and cryptorchidism in Thoroughbreds and/or Quarter Horses. No significant associations were detected between laryngeal hemiplegia and any ELA antigen in Thoroughbreds. The association between arytenoid chondritis and A9 was significant with a relative risk (RR) of 15.6 and aetiologic fraction (EF) of 0.80 in Thoroughbreds. There were apparent associations based on RR between A4 and A5 in Quarter Horses with umbilical hernias (RR = 7.5 and 6.1 respective...
Body condition scoring and weight estimation of horses.
Equine veterinary journal    January 1, 1988   Volume 20, Issue 1 41-45 doi: 10.1111/j.2042-3306.1988.tb01451.x
Carroll CL, Huntington PJ.Three hundred and seventy two horses of varying breeds, height and fatness were weighed and measured for height at the withers. They were assessed for condition score by adaptation of a previously published method. The heart girth and length of 281 of the horses were also measured. Weight of horses was highly correlated (P less than 0.001) with height (r2 = 0.62), condition score (r2 = 0.22) and girth2 x length (r2 = 0.90). Nomograms were constructed to predict weight from height and condition score, and girth and length measurements. Weight can also be accurately estimated from the formula: (...
Evaluation of breed as a risk factor for sarcoid and uveitis in horses.
Animal genetics    January 1, 1988   Volume 19, Issue 4 417-425 doi: 10.1111/j.1365-2052.1988.tb00833.x
Angelos J, Oppenheim Y, Rebhun W, Mohammed H, Antczak DF.The relationship between breed and the risk of developing sarcoid tumours or uveitis of unknown etiology was evaluated in a retrospective study of 16242 equine cases admitted between 1975 and 1987 to the New York State College of Veterinary Medicine Large Animal Hospital, and 3198 equine tissue samples sent to the New York State Veterinary Diagnostic Laboratory between 1977 and 1987. Of 120 sarcoid cases from the Large Animal Hospital, sarcoids were twice as likely to develop in Quarter Horses (odds ratio, OR = 1.8, P less than 0.05) relative to Thoroughbreds and less than half as likely to de...
Neuroendocrine changes produced by competition stress on the Thoroughbred race horse.
Comparative biochemistry and physiology. A, Comparative physiology    January 1, 1988   Volume 91, Issue 3 599-602 doi: 10.1016/0300-9629(88)90640-8
Martínez R, Godoy A, Naretto E, White A.1. Packed cell volume (PCV) and plasma catecholamines, cortisol and glucose were determined in blood samples obtained from race horses, after competition. 2. All these parameters were higher than basals but catecholamines increased 6-7 times while cortisol was enhanced only by 25%. 3. The increase of glucose and PCV was related to the rise of catecholamines. 4. In samples withdrawn after overnight stress caused by change of horseshoes, it was not possible to find values from basal values significantly different. 5. Influence of nervous temperament was observed only in the higher hematocrit fou...
[Iron and iron-binding capacity in the serum of clinically healthy horses].
Tierarztliche Praxis    January 1, 1988   Volume 16, Issue 2 163-165 
Schorr G.Serum iron concentration and iron-binding capacity were determined in 34 respectively 35 clinically healthy horses of different sex, with the age of 3 to 21 years. In the Warm blooded horse, the Half bred, the Haflinger horse, the Heavy horse and the Arabian Haflinger the mean serum iron concentration amounted to 253 +/- 66 micrograms/dl, 202 +/- 87 micrograms/dl, 166 +/- 67 micrograms/dl, 183 micrograms/dl and 366 micrograms/dl, while the iron-binding capacity in the Warm blooded horse, the Half bred, the Haflinger horse, the Thoroughbred, the Heavy horse and the Arabian Haflinger ran up to 4...
Circulatory, respiratory and metabolic responses in Thoroughbred horses during the first 400 meters of exercise.
European journal of applied physiology and occupational physiology    January 1, 1988   Volume 58, Issue 3 307-314 doi: 10.1007/BF00417268
Littlejohn A, Snow DH.These studies investigated circulatory, respiratory and metabolic responses in four Thoroughbred geldings during the first 400 metres of galloping (mean speed 14.4 +/- 0.38 m.s-1), cantering (mean speed 10.0 +/- 0.61 m.s-1) and walking (mean speed 1.58 +/- 0.05 m.s-1) from a standing start. A radio-controlled device which collected blood samples anaerobically during each 100 m section of the exercise track allowed analyses of changes in and functional relationships of the variables measured. During the 400 m gallop, the mean heart rate (HR) increased from 125 to 201 beats.min-1 and the haemato...