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Topic:Thoroughbreds

Thoroughbreds are a breed of horse known for their agility, speed, and spirit, often associated with horse racing and equestrian sports. Originating from crossbreeding native English mares with imported Arabian, Barb, and Turkoman stallions, Thoroughbreds have a well-documented pedigree that traces back to the late 17th and early 18th centuries. This breed is characterized by a refined head, deep chest, and long legs, contributing to their athletic capabilities. Thoroughbreds are primarily bred for their performance in racing but are also utilized in other equestrian disciplines. This page compiles peer-reviewed research studies and scholarly articles that explore the genetics, physiology, and performance characteristics of Thoroughbreds, as well as their management and welfare in various equine activities.
The influence of exercise on the daily rhythm of serum homocysteine in horses.
The journal of physiological sciences : JPS    November 11, 2006   Volume 56, Issue 6 455-458 doi: 10.2170/physiolsci.SC009106
Fazio F, Assenza A, Crisafulli G, Piccione G, Caola G.The aim of this study was to determine the daily rhythms in the blood serum of homocysteine in horses. Ten thoroughbred horses, five athletic (trained for 1 h, 6 days a week) and five sedentary, were used. Blood samples were collected on each subject every 4 h for two days by means of the jugular vein. On each individual sample, the serum concentration of homocysteine was assessed. The results obtained during the experimental period indicated the existence of a daily rhythm of serum homocysteine in sedentary and athletic horses. They also demonstrated that in horses, physical exercise influenc...
The effect of current grain feeding practices on hindgut starch fermentation and acidosis in the Australian racing Thoroughbred.
Australian veterinary journal    November 10, 2006   Volume 84, Issue 11 402-407 doi: 10.1111/j.1751-0813.2006.00059.x
Richards N, Hinch G, Rowe J.A survey of 72 thoroughbred trainers in several regions of NSW was conducted to better define current grain feeding practices, and the risks involved with grain feeding in the Australian thoroughbred racing industry. Results from the survey indicate that horses in the industry are currently being fed an average of 7.3 +/- 0.23 kg of grain concentrate per day, with oats, commercial pre-mixed diets and corn most commonly used. The feeding of extruded, micronised and steam flaked grains was uncommon. The results of grain and faecal sample analyses conducted during the survey indicate that incompl...
Septic epiglottic chondritis with abscessation in 2 young Thoroughbred racehorses.
The Canadian veterinary journal = La revue veterinaire canadienne    November 3, 2006   Volume 47, Issue 10 1007-1010 
Infernuso T, Watts AE, Ducharme NG.Septic epiglottic chondritis with abscessation diagnosed in 2 Thoroughbred racehorses. Infected cartilage removed videoendoscopically followed by systemic antibiotics. The infectious process was successfully controlled, but permanent dorsal displacement of the soft palate (DDSP) with a shortened, deformed epiglottic cartilage developed. Surgery for the DDSP using bilateral partial sternothyroidectomy or laryngeal tie-forward failed. Chondrite septique abcédée de l’épiglotte chez 2 jeunes chevaux de course Thoroughbred. Une chondrite septique abcédée de l’épiglotte a été diagnostiqu...
Effect of speed on stride parameters in racehorses at gallop in field conditions.
The Journal of experimental biology    October 20, 2006   Volume 209, Issue Pt 21 4389-4397 doi: 10.1242/jeb.02518
Witte TH, Hirst CV, Wilson AM.Stride duration, stance duration and protraction duration are key variables when describing the gaits of terrestrial animals. Together, they determine the duty factor (the fraction of the stride for which the limb maintains contact with the ground surface), from which the peak vertical force can be estimated. When an animal changes speed, these variables change at different proportions. Limited measurements of these variables and predictions of peak limb force have been undertaken for large mammals performing high-speed over-ground exercise. This study set out to make such measurements, employ...
Do the matrix degrading enzymes cathepsins B and D increase following a high intensity exercise regime?
Osteoarthritis and cartilage    October 19, 2006   Volume 15, Issue 3 343-349 doi: 10.1016/j.joca.2006.08.014
Bowe EA, Murray RC, Jeffcott LB, Davies ME.It has been shown by others that levels of matrix degrading enzymes are increased in osteoarthritis (OA) and so are proposed to be involved in the aetiopathogenesis of the disease, including exercise-associated OA. Therefore we hypothesised that cathepsin B and cathepsin D were increased in cartilage samples previously shown to have early stage OA from 2-year-old Thoroughbred horses, euthanased for reasons other than this study, that had a history of 19-week high intensity exercise (n=6) compared to age and sex-matched horses with a history of low intensity exercise (n=6). Methods: Cartilage s...
The effects of equine skin preparation on transdermal drug penetration in vitro.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire    October 18, 2006   Volume 70, Issue 4 317-320 
Mills PC, Cross SE.An increasing number of formulations are applied to equine skin, yet variable penetration can affect efficacy, or the incidence of adverse effects, or both. To investigate the effects of common methods of skin preparation on transdermal drug penetration in vitro, we clipped, harvested, and froze skin samples from 5 Thoroughbred geldings. Thawed samples were prepared as follows: control (no preparation); cleaned with aqueous chlorhexidine (Aq-C, 0.1% w/v); cleaned with alcoholic chlorhexidine (Al-C, 0.5% w/v); shaved (Sh); or tape-stripped (Ta) with the use of adhesive tape. The samples were th...
Voluntary intake and digestibility of reed canarygrass and timothy hay fed to horses.
Journal of animal science    October 13, 2006   Volume 84, Issue 11 3104-3109 doi: 10.2527/jas.2005-607
Ordakowski-Burk AL, Quinn RW, Shellem TA, Vough LR.Thousands of hectares of timothy (Phleum pretense L.) grown in the Mid-Atlantic region are infected by cereal rust mite (Abacarus hysterix) that causes discoloration and curling of leaves, decreased nutritional quality, and substantial decreases in yield. A decline in production of timothy hay can lower income for hay producers and cause horse owners to search for alternative hays. Low alkaloid reed canarygrass (Phalaris arundinacea L.) hay has potential as an alternative to timothy hay because it grows well in the Mid-Atlantic region, is believed to have a similar nutrient quality to timothy,...
Ventriculocordectomy as the sole treatment for recurrent laryngeal neuropathy: long-term results from ninety-two horses.
Veterinary surgery : VS    October 10, 2006   Volume 35, Issue 7 653-657 doi: 10.1111/j.1532-950X.2006.00203.x
Taylor SE, Barakzai SZ, Dixon P.To evaluate the effect ventriculocordectomy (VC) for treatment of recurrent laryngeal neuropathy (RLN) on exercise performance and owner satisfaction in a mixed-breed population of horses. Methods: Retrospective study. Methods: Adult horses (n=92) with a history of abnormal respiratory noise and RLN. Methods: Retrospective analysis of horse that had unilateral VC (and contralateral ventriculectomy in 63 horses) for treatment of idiopathic RLN. Owners/trainers completed a questionnaire about complications and outcome at least 1 year after surgery. Performance index was determined using race rec...
Comparison of radiography and computed tomography to evaluate metacarpo/metatarsophalangeal joint pathology of paired limbs of thoroughbred racehorses with severe condylar fracture.
Veterinary surgery : VS    October 10, 2006   Volume 35, Issue 7 611-617 doi: 10.1111/j.1532-950X.2006.00198.x
Morgan JW, Santschi EM, Zekas LJ, Scollay-Ward MC, Markel MD, Radtke CL, Sample SJ, Keuler NS, Muir P.To compare the orthogonal radiographic (OR) and computed tomographic (CT) appearance of paired Thoroughbred racehorse limbs with severe condylar fracture. Methods: In vitro study. Methods: Cadaveric paired limbs with severe condylar fracture (n=11 horses). Methods: Four standard radiographic and multiple transverse CT images were obtained of the fractured and contralateral limbs centering on the metacarpo/metatarsophalangeal (fetlock) joints. Radiographs and CT images were graded by 4 raters, and interobserver agreement was calculated. Imaging evaluations were supplemented by fetlock joint dis...
Parasite field study in central Kentucky on thoroughbred foals (born in 2004) treated with pyrantel tartrate daily and other parasiticides periodically.
Parasitology research    September 30, 2006   Volume 100, Issue 3 473-478 doi: 10.1007/s00436-006-0289-6
Lyons ET, Tolliver SC, Rathgeber RA, Collins SS.Foals (79), born in 2004 on three thoroughbred horse farms (C, M, and S) in central Kentucky, were fed pyrantel tartrate daily, beginning at about 3 months of age. In addition, other parasiticides [fenbendazole (FBZ), ivermectin (IVM) alone or with praziquantel (PRAZ), oxibendazole (OBZ), pyrantel pamoate (PRT), and moxidectin (MOX)] were given periodically. All treatments were administered by farm personnel. Over a 14-month period, from May 2004 to July 2005, collections (n=989) of feces were made from the foals for determination of presence of internal parasite eggs/oocysts by qualitative an...
Fracture rate in Thoroughbred racehorses is affected by dam age and parity.
Veterinary journal (London, England : 1997)    September 25, 2006   Volume 174, Issue 2 295-301 doi: 10.1016/j.tvjl.2006.07.023
Verheyen KL, Price JS, Wood JL.This study's aim was to determine the effects of dam age and parity on the rate of fracture in offspring in Thoroughbred racehorses in training for flat racing. It was hypothesised that first foals and those from older mares would have a higher fracture rate than subsequent foals and those from younger mares. A two-year observational cohort study collected data from eight trainers on 335 horses that were monitored since the start of their training as yearlings. Multivariable Poisson regression analyses showed that first foals had a significantly lower fracture rate than subsequent ones (RR=0.3...
Racing performance after arthroscopic removal of apical sesamoid fracture fragments in Thoroughbred horses age > or = 2 years: 84 cases (1989-2002).
Equine veterinary journal    September 22, 2006   Volume 38, Issue 5 446-451 doi: 10.2746/042516406778400655
Schnabel LV, Bramlage LR, Mohammed HO, Embertson RM, Ruggles AJ, Hopper SA.Studies have shown that surgical removal of apical fracture fragments in Standardbred racehorses carries the best prognosis for return to racing performance, but there are no reports involving mature Thoroughbred (TB) racehorses. Objective: To describe the incidence of apical proximal sesamoid fractures in TB racehorses and determine probability and quality of racing performance after arthroscopic removal of such fractures in TB racehorses age > or = 2 years. Methods: Medical records and pre- and post operative race records of TB racehorses age > or = 2 years that underwent arthroscopic surger...
Dynamic obstructions of the equine upper respiratory tract. Part 2: comparison of endoscopic findings at rest and during high-speed treadmill exercise of 600 Thoroughbred racehorses.
Equine veterinary journal    September 22, 2006   Volume 38, Issue 5 401-407 doi: 10.2746/042516406778400619
Lane JG, Bladon B, Little DR, Naylor JR, Franklin SH.The reliability of diagnoses of obstructive conditions of the upper respiratory tract (URT) based on examinations performed at rest vs. at exercise is controversial. Objective: To compare diagnosis of URT by endoscopy at rest with that achieved during high-speed treadmill exercise (HSTE). Objective: Endoscopy of URT at rest, when performed in isolation from other simpler techniques is unreliable in the prediction of dynamic respiratory obstructions. Methods: Endoscopic findings of 600 Thoroughbred racehorses during quiet breathing were compared with findings during high-speed treadmill exercis...
Dynamic obstructions of the equine upper respiratory tract. Part 1: observations during high-speed treadmill endoscopy of 600 Thoroughbred racehorses.
Equine veterinary journal    September 22, 2006   Volume 38, Issue 5 393-399 doi: 10.2746/042516406778400583
Lane JG, Bladon B, Little DR, Naylor JR, Franklin SH.To review the prevalence of single and complex forms of dynamic airway obstructions within a large group of Thoroughbred horses in training referred for investigation of poor performance. Methods: Video-endoscopic recordings of the upper respiratory tract made during a standardised treadmill exercise test of 600 Thoroughbred racehorses were reviewed and analysed in real time and slow motion to identify dynamic collapse by the tissues bordering onto the pharyngeal and laryngeal airways. Results: Dynamic collapse within the nasopharynx or larynx was confirmed in 471 of the 600 horses. Dorsal dis...
Centre of mass movement and mechanical energy fluctuation during gallop locomotion in the Thoroughbred racehorse.
The Journal of experimental biology    September 21, 2006   Volume 209, Issue Pt 19 3742-3757 doi: 10.1242/jeb.02439
Pfau T, Witte TH, Wilson AM.During locomotion cyclical interchange between different forms of mechanical energy enhances economy; however, 100% efficiency cannot be achieved and ultimately some mechanical work must be performed de novo. There is a metabolic cost associated with fluctuations in mechanical energy, even in the most efficient animals. In this study we investigate the exchanges between different forms of mechanical energy involved in high-speed gallop locomotion in Thoroughbred race horses during over-ground locomotion using innovative, mobile data collection techniques. We use hoof-mounted accelerometers to ...
Analysis of genetic diversity and the determination of relationships among western Mediterranean horse breeds using microsatellite markers.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie    September 13, 2006   Volume 123, Issue 5 315-325 doi: 10.1111/j.1439-0388.2006.00603.x
Marletta D, Tupac-Yupanqui I, Bordonaro S, García D, Guastella AM, Criscione A, Cañón J, Dunner S.The distribution of genetic diversity and the genetic relationships among western Mediterranean horse breeds were investigated using microsatellite markers. The examined sample included seven Spanish and three Italian local horse breeds and populations, plus a Spanish Thoroughbred outgroup. The total number of animals examined was 682 (on average 62 animals per breed; range 20-122). The microsatellite marker set analysed provided 128 alleles (10.7 alleles per locus). Within-breed genetic diversity was always high (>0.70), with breeds contributing about 8% of the total genetic variability. T...
Intraosseous epidermoid cyst of the third phalanx in a thoroughbred gelding.
The Veterinary record    September 12, 2006   Volume 159, Issue 11 360-362 doi: 10.1136/vr.159.11.360
Fraser B, Else RW, Jones E.No abstract available
Congenital perianal fistula in a thoroughbred colt.
The Veterinary record    September 12, 2006   Volume 159, Issue 11 362-364 doi: 10.1136/vr.159.11.362
Kearney CM, Pollock PJ.No abstract available
Prevalence of serum neutralising antibody to equine rhinitis A virus (ERAV), equine rhinitis B virus 1 (ERBV1) and ERBV2.
Veterinary microbiology    September 10, 2006   Volume 119, Issue 1 65-71 doi: 10.1016/j.vetmic.2006.08.031
Black WD, Wilcox RS, Stevenson RA, Hartley CA, Ficorilli NP, Gilkerson JR, Studdert MJ.The objective of this study was to determine the incidence of serum neutralising (SN) antibody to ERAV, ERBV1 and ERBV2 in a population of horses from birth to 22 years of age. The prevalences of ERAV, ERBV1 and ERBV2 SN antibodies in 381 sera obtained from 291 horses were 37%, 83% and 66%, respectively. ERAV, ERBV1 and ERBV2 maternal antibody was present in foals 12 h postsuckling but by 10-12 months, ERAV SN antibody was not detected in any of the horses, while ERBV1 and ERBV2 SN antibodies were common (83% and 100%, respectively). Sera were obtained from 44 Thoroughbred horses when they wer...
Serum and plasma cardiac troponin I concentrations in clinically normal Thoroughbreds in training in Australia.
Australian veterinary journal    September 9, 2006   Volume 84, Issue 9 336-337 doi: 10.1111/j.1751-0813.2006.00025.x
Begg LM, Hoffmann KL, Begg AP.Cardiac troponin I is a potentially useful test to identify cardiac muscle damage in the horse. Measurements of cardiac troponin I from serum or heparinised plasma samples from 23 clinically normal Thoroughbred horses in race training were analysed through a standard Australian commercial laboratory using the ADVIA Centaur Assay. The cardiac troponin I concentrations were < 0.15 microg/L from all samples. The test was then validated using macerated equine myocardium. Cardiac troponin I concentration may be useful in determining whether poor performance in Thoroughbred horses is related to a...
Associations between the ecology of virulent Rhodococcus equi and the epidemiology of R. equi pneumonia on Australian thoroughbred farms.
Applied and environmental microbiology    September 8, 2006   Volume 72, Issue 9 6152-6160 doi: 10.1128/AEM.00495-06
Muscatello G, Anderson GA, Gilkerson JR, Browning GF.The ecology of virulent strains of Rhodococcus equi on horse farms is likely to influence the prevalence and severity of R. equi pneumonia in foals. This study examined the association between the ecology of virulent R. equi and the epidemiology of R. equi pneumonia by collecting air and soil samples over two breeding seasons (28 farm-year combinations) on Thoroughbred breeding farms with different reported prevalences of R. equi pneumonia. Colony blotting and DNA hybridization were used to detect and measure concentrations of virulent R. equi. The prevalence of R. equi pneumonia was associate...
Persistence of serum antibodies to Sarcocystis neurona in horses moved from North America to India.
Journal of veterinary internal medicine    September 8, 2006   Volume 20, Issue 4 994-997 doi: 10.1892/0891-6640(2006)20[994:posats]2.0.co;2
Brown CM, Morrow JK, Carleton CL, Ramanathan B, Reddy R, Vaidya V, Karthikeyan SM, Zulfikar AA, Kannadkar VS.The study reported here was undertaken to assess the presence of antibodies to Sarcocystis neurona in the serum of horses of North American origin that had been relocated for 1 year or more to India (ie, outside of the known endemic areas for S. neurona). Objective: The presence or absence of such antibodies should provide information concerning the persistence of such antibodies, or support the presence of chronic infection, or both. Methods: A total of 228 Thoroughbred horses were sampled in India, of which 86 were of North American origin that had been in India between 1 and 13 years, 124 w...
Macrocyclic lactone-resistant Parascaris equorum on stud farms in Canada and effectiveness of fenbendazole and pyrantel pamoate.
Veterinary parasitology    September 7, 2006   Volume 145, Issue 3-4 371-376 doi: 10.1016/j.vetpar.2006.08.008
Slocombe JO, de Gannes RV, Lake MC.The aims of studies in 2002 and 2003 on three farms with 76 foals naturally infected with Parascaris equorum were to (i) identify if the nematode was resistant to ivermectin and moxidectin, and (ii) confirm the effectiveness of fenbendazole and pyrantel pamoate for the parasite. Twelve clinical trials, each with a Fecal Egg Count Reduction Test, were conducted on two Thoroughbred and one Standardbred farms in southwestern Ontario, Canada. In each trial, Parascaris eggs/g feces were estimated for each foal pre- and post-treatment using the Cornell-Wisconsin double flotation and Cornell-McMaster...
Cardiovascular effects of continuous propofol infusion in horses.
The Journal of veterinary medical science    September 6, 2006   Volume 68, Issue 8 773-778 doi: 10.1292/jvms.68.773
Oku K, Ohta M, Katoh T, Moriyama H, Kusano K, Fujinaga T.We examined the influence of propofol infusion on cardiovascular system at the rate of 0.14, 0.20 and 0.30 mg/kg/min in six adult Thoroughbred horses. The cardiovascular parameters were heart rate (HR), mean arterial pressure (MAP), mean right atrial pressure (MRAP), stroke volume (SV), cardiac output (CO), systemic vascular resistance (SVR), pre-ejection period (PEP) and ejection time (ET). In order to keep the ventilation conditions constantly, intermittent positive pressure ventilation was performed, and the partial arterial CO(2) pressure was maintained at 45 to 55 mmHg during maintenance ...
Relationship between stages of the estrous cycle and bone cell activity in Thoroughbreds.
American journal of veterinary research    September 5, 2006   Volume 67, Issue 9 1527-1532 doi: 10.2460/ajvr.67.9.1527
Jackson BF, Dyson PK, Hattersley RD, Kelly HR, Pfeiffer DU, Price JS.To investigate the relationship between stage of estrous cycle and bone cell activity in Thoroughbreds. Methods: Blood samples collected from forty-seven 2-year-old Thoroughbred mares in training for racing. Methods: Blood samples were collected monthly (in April through September) from the mares. Stage of estrus was determined by assessing serum progesterone concentration. Bone cell activity was determined by measuring concentrations of 2 markers of bone formation (osteocalcin and the carboxy-terminal propeptide of type I collagen [PICP]) and a marker of bone resorption (the cross-linked carb...
Congenital diaphragmatic eventration in a stillborn foal. Jackson C, Collyer PB, Loynachan A.A stillborn full term foal was presented at necropsy. The dilated duodenum and the dorsal and ventral left colon and cecum extended into the thoracic cavity and were encased by a thin transparent membrane originating from the diaphragm. The congenital condition was diagnosed as a developmental anomaly with diaphragmatic eventration. To the authors' knowledge, this is the first report of diaphragmatic eventration in a Thoroughbred stillborn foal.
Exercise distance and speed affect the risk of fracture in racehorses.
Bone    August 22, 2006   Volume 39, Issue 6 1322-1330 doi: 10.1016/j.bone.2006.05.025
Verheyen K, Price J, Lanyon L, Wood J.In order to gain insight into those training regimens that can minimise the risk of fracture in athletic populations, we conducted a large epidemiological study in racehorses. Thoroughbred racehorses provide a suitable model for studying fracture development and exercise-related risk factors in physically active populations. They represent a homogeneous population, undertaking intensive exercise programmes that are sufficiently heterogeneous to determine those factors that influence injury risk. Daily exercise information was recorded for a cohort of 1178 thoroughbreds that were monitored for ...
Arytenoid mucosal injury in young Thoroughbred horses–investigation of a proposed aetiology and clinical significance.
New Zealand veterinary journal    August 18, 2006   Volume 54, Issue 4 173-177 doi: 10.1080/00480169.2006.36691
Smith RL, Perkins NR, Firth EC, Anderson BH.To determine whether trauma to the larynx caused by nasotracheal intubation induced mucosal ulceration of the arytenoid cartilages of adult horses, and to determine the incidence of such ulceration in yearling Thoroughbred horses and its effect on athletic performance. Methods: Laryngeal trauma was induced in a group of 21 adult horses by introduction of a nasogastric tube into the trachea three times within 5 min. Injury to the arytenoid cartilages or vocal cords was subjectively assessed immediately after intubation, and thereafter at weekly intervals for 10 weeks. The outcome and athletic p...
Placement of a long term tracheal cannula in a Thoroughbred racehorse with bilateral laryngeal dysfunction.
Australian veterinary journal    August 17, 2006   Volume 84, Issue 8 293-296 doi: 10.1111/j.1751-0813.2006.00016.x
Schaaf KL, Kannegieter NJ, Lovell DK.A Thoroughbred horse with bilateral laryngeal dysfunction was treated by placement of a long term tracheal cannula in order to restore full athletic function. The horse initially presented with right-sided arytenoid dysfunction that was considered to be due to a congenital malformation of the laryngeal cartilage. This was corrected by a right-sided laryngoplasty and ventriculectomy. The horse re-presented 1 year later with idiopathic left laryngeal hemiplegia. The decision was made to place a long-term tracheal cannula due to the low success rate and high complication rate associated with othe...
Limb fractures more common in French than British jockeys.
Nursing standard (Royal College of Nursing (Great Britain) : 1987)    August 16, 2006   Volume 20, Issue 49 19 doi: 10.7748/ns.20.49.19.s23
French jockeys suffer more severe injuries when they fall off their horses than their British counterparts. While it has been shown that jockeys suffer high rates of fatal and non-fatal injuries, little is known about differences in injury rates between countries. To investigate this, researchers from Australia, France and the UK used prospectively collected data on the rates of fatal and non-fatal injuries in flat and jump jockeys in France and compared them with data from the UK.
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