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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Mechanisms of gastrointestinal ischemia-reperfusion injury and potential therapeutic interventions: a review and its implications in the horse.
Journal of veterinary internal medicine    May 1, 1995   Volume 9, Issue 3 115-132 doi: 10.1111/j.1939-1676.1995.tb03285.x
Moore RM, Muir WW, Granger DN.Restoration of blood flow after a period of intestinal ischemia is necessary to maintain cell function and viability; however, the reintroduction of oxygen can initiate a cascade of events that exacerbates tissue injury. Intestinal I-R injury is manifested as increased microvascular and mucosal permeability, and mucosal necrosis. Reperfusion injury begins with the accumulation of hypoxanthine from ATP metabolism and the conversion of XDH to XO during ischemia. Upon reperfusion, the XO catalyzes the conversion of hypoxanthine to superoxide radicals in the presence of oxygen. Superoxide radicals...
Permanent tracheostomy in standing horses: technique and results.
Veterinary surgery : VS    May 1, 1995   Volume 24, Issue 3 231-234 doi: 10.1111/j.1532-950x.1995.tb01323.x
McClure SR, Taylor TS, Honnas CM, Schumacher J, Chaffin MK, Hoffman AG.Permanent tracheal stomas were created in seven sedated, standing horses with severe upper airway obstruction. After local anesthesia, a 3-cm by 6-cm rectangle of skin was removed from the ventral surface of the neck, 3 cm distal to the cricoid cartilage. The sternothyrohyoideus muscles were clamped proximally and distally, then transected to expose the tracheal rings. The ventral third of four tracheal rings was dissected from the tracheal mucosa that was then incised in a double "Y." Two layers of suture were used to achieve mucocutaneous closure. Stomas healed without serious complications;...
Comparative RAPD-PCR analysis of lungworms (Dictyocaulidae) from fallow deer, cattle, sheep, and horses.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B    May 1, 1995   Volume 42, Issue 3 187-191 doi: 10.1111/j.1439-0450.1995.tb00699.x
Epe C, Bienioschek S, Rehbein S, Schnieder T.Genomic DNA isolated from the four Dictyocaulus species D. viviparus, D. eckerti, D. filaria and D. arnfieldi was compared by random amplified polymorphic DNA polymerase chain reaction (RAPD)-PCR to get additional information whether lungworms from fallow deer belong to a separate species (D. eckerti) or have to be regarded as an isolate of D. viviparus in wild ruminants. The resulting banding patterns of the electrophoresed PCR products were compared to assess the degree of genetic differences between the different lungworms. For the two D. viviparus isolates a similarity coefficient of 93.4%...
Cowboy care.
Emergency medical services    May 1, 1995   Volume 24, Issue 5 24-30 
Hamilton AJ.No abstract available
Morphologic changes of the ascending colon during experimental ischemia and reperfusion in ponies.
Veterinary pathology    May 1, 1995   Volume 32, Issue 3 280-288 doi: 10.1177/030098589503200310
Darien BJ, Stone WC, Dubielzig RR, Clayton MK.The morphologic changes following ascending colon volvulus result from the interaction of inflammatory and coagulation mediators. The objective of this study was to establish a quantifiable histopathologic scoring system to evaluate the serial pathomorphologic changes during ischemia and reperfusion. Such a scoring system could then be applied to subsequent studies designed to attenuate bowel lesions by regulating activity of individual mediators. Ten normal, healthy adult ponies were randomly divided into two equal groups. Following anesthesia and a 30-minute stabilization period, the colon o...
Clinical, pathological and epidemiological aspects of flood plain staggers, a corynetoxicosis of livestock grazing Agrostis avenacea.
Australian veterinary journal    May 1, 1995   Volume 72, Issue 5 187-190 doi: 10.1111/j.1751-0813.1995.tb03187.x
Davis EO, Curran GE, Hetherington WT, Norris DA, Wise GA, Roth IJ, SeaWright AA, Bryden WL.Flood plain staggers, a corynetoxicosis of grazing livestock, occurred on flood plains of the Darling river in northern New South Wales between spring 1990 and autumn 1991, associated with the grazing of Agrostis avenacea with diseased inflorescences. Over this period 1722 cattle, 2466 sheep and 11 horses died on 31 farms. Clinical signs were similar in sheep and cattle, being characterised by intermittent episodes of cerebral convulsion superimposed on varying degrees of cerebellar dysfunction. Pathological changes were variable and non-specific, principally reflecting trauma and the generali...
Plasma atrial natriuretic peptide in standardbred and Finnhorse trotters during and after exercise.
Acta physiologica Scandinavica    May 1, 1995   Volume 154, Issue 1 51-58 doi: 10.1111/j.1748-1716.1995.tb09885.x
Kokkonen UM, Hackzell M, Räsänen LA.To study the exercise-induced changes in atrial natriuretic peptide (ANP), a hormone with cardiovascular and renal effects, an incremental submaximal exercise test on a high-speed treadmill was carried out with Standardbred and Finnhorse trotters, the former bred for speed and the latter originally for heavy work. Standardbreds performed the 2 min exercise intervals at speeds of 6, 7, 8, 9 m s-1 and Finnhorses, according to their training status, at 5, 6, 7, 8 m s-1, 4, 5, 6, 7 m s-1 or 5, 6, 7 m s-1. Steady-state heart rate (HR) was reached within each 2 min interval. The increase in HR was l...
Development of an ELISA using a universal method of enzyme-labelling drug-specific antibodies. Part I: Detection of dexamethasone in equine urine.
Journal of immunological methods    April 26, 1995   Volume 181, Issue 2 157-166 doi: 10.1016/0022-1759(94)00342-t
Roberts CJ, Jackson LS.The development, validation, and application of an ELISA for dexamethasone in equine urine is described. The drug-protein conjugate was immobilised in microtitre plate wells and antiserum raised against the same drug-protein conjugate was allowed to compete with sample or standard drug and the immobilised drug-protein conjugate. The proportion of antiserum binding to the immobilised drug-protein conjugate was detected using a biotinylated protein G/extravidin-alkaline phosphatase complex in situ and measurement of the substrate product. The method was used to detect the presence of drug-derive...
A novel Ca(2+)-dependent step in exocytosis subsequent to vesicle fusion.
FEBS letters    April 24, 1995   Volume 363, Issue 3 217-220 doi: 10.1016/0014-5793(95)00318-4
Hartmann J, Lindau M.Exocytosis begins with formation of a small fusion pore which then expands allowing rapid release of granular contents. We studied the influence of cytoplasmic free Ca2+ ([Ca2+]i) on the conductance of the initial pore and on the dynamics of subsequent expansion in horse eosinophils using the patch clamp technique. The mean initial conductance is approximately 200 pS independent of [Ca2+]i. This value is close to that previously found in beige mouse mast cells. The pore subsequently expands by 18 nS/s at [Ca2+]i < 10 nM, by 40 nS/s at [Ca2+]i = 1.5 microM and by 90 nS/s at [Ca2+]i = 10 micr...
Spontaneous otoacoustic emission in a pony.
The Veterinary record    April 22, 1995   Volume 136, Issue 16 419 doi: 10.1136/vr.136.16.419
Mayhew IG, Preston SE, Hannant D, Washbourne JR, Johnson CB, Phillips TJ.No abstract available
Oestrogens in mares’ urine.
The Veterinary record    April 22, 1995   Volume 136, Issue 16 424 doi: 10.1136/vr.136.16.424
Watkins CW.No abstract available
First recorded outbreak of equine viral arteritis in the United Kingdom.
The Veterinary record    April 15, 1995   Volume 136, Issue 15 381-385 doi: 10.1136/vr.136.15.381
Wood JL, Chirnside ED, Mumford JA, Higgins AJ.Equine viral arteritis was diagnosed for the first time in the United Kingdom in 1993. The outbreak began on a non-thoroughbred stud in south Nottinghamshire and spread to five other premises through chilled semen used for artificial insemination and from acutely and subclinically infected mares returning home. The outbreak was contained on these six premises by means of voluntary movement restrictions. The most commonly observed clinical signs were typical: pyrexia with depression, and conjunctivitis with periorbital oedema; nasal discharge, and oedema of the distal limbs, prepuce and mammary...
Use of autogenous cancellous bone grafting in the treatment of septic navicular bursitis and distal sesamoid osteomyelitis in horses.
Journal of the American Veterinary Medical Association    April 15, 1995   Volume 206, Issue 8 1191-1194 
Honnas CM, Crabill MR, Mackie JT, Yarbrough TB, Schumacher J.Six horses with septic navicular bursitis or distal sesamoid osteomyelitis were treated by means of surgical debridement and lavage, followed by packing of the wound created in the bottom of the foot with an autogenous cancellous bone graft. Two horses were euthanatized, one 18 months after surgery because of complications in the contralateral support limb, and one 68 days after surgery because of continuing severe lameness. Four horses were alive 9, 16, 21, and 42 months after surgery. One horse was used as a broodmare and did not have observable lameness. Two horses were being ridden. The re...
Lag screw fixation of noncomminuted sagittal fractures of the proximal phalanx in racehorses: 59 cases (1973-1991).
Journal of the American Veterinary Medical Association    April 15, 1995   Volume 206, Issue 8 1195-1199 
Holcombe SJ, Schneider RK, Bramlage LR, Gabel AA, Bertone AL, Beard WL.Medical records of 59 racehorses with noncomminuted midsagittal proximal phalanx fractures repaired by means of lag screw fixation between 1973 and 1991 were reviewed. Fractures were classified as short incomplete fractures (7), long incomplete fractures (32), complete fractures extending into the proximal interphalangeal joint (13), and complete fractures extending through the lateral cortex of the proximal phalanx (7). Time from fracture repair to first race following fracture repair, number of racing starts, and fastest race times before and after surgery were obtained from race records and...
A morbillivirus that caused fatal disease in horses and humans.
Science (New York, N.Y.)    April 7, 1995   Volume 268, Issue 5207 94-97 doi: 10.1126/science.7701348
Murray K, Selleck P, Hooper P, Hyatt A, Gould A, Gleeson L, Westbury H, Hiley L, Selvey L, Rodwell B.A morbillivirus has been isolated and added to an increasing list of emerging viral diseases. This virus caused an outbreak of fatal respiratory disease in horses and humans. Genetic analyses show it to be only distantly related to the classic morbilliviruses rinderpest, measles, and canine distemper. When seen by electron microscopy, viruses had 10- and 18-nanometer surface projections that gave them a "double-fringed" appearance. The virus induced syncytia that developed in the endothelium of blood vessels, particularly the lungs.
Laparoscopic anatomy of the equine abdomen.
American journal of veterinary research    April 1, 1995   Volume 56, Issue 4 518-531 
Galuppo LD, Snyder JR, Pascoe JR.Laparoscopy was performed on 6 horses (2 mares, 2 geldings, 2 stallions) to determine the normal laparoscopic anatomy of the equine abdomen. After withholding feed for 36 hours, horses were examined from the left and right paralumbar fossae, and the visceral anatomic structures were recorded by videotape and photography. One mare developed emphysema located subcutaneously at the primary laparoscopic portal; otherwise, there were no complications. The anatomic structures of diagnostic importance that were observed in the left half of the abdomen were the hepatic duct; left lateral and quadrate ...
Acute spinal cord degeneration following general anaesthesia in a young pony.
The Veterinary record    April 1, 1995   Volume 136, Issue 13 329-330 doi: 10.1136/vr.136.13.329
Lam KH, Smyth JB, Clarke K, Platt D.No abstract available
Internal diseases that have skin lesions.
The Veterinary clinics of North America. Equine practice    April 1, 1995   Volume 11, Issue 1 111-126 doi: 10.1016/s0749-0739(17)30336-x
Woods PR.Skin lesions can be associated with many internal diseases. Most organ systems seem to have conditions in which skin lesions can develop. Treatment of the skin lesions in such a situation is palliative. The underlying internal disease must be addressed for resolution of the skin lesions to occur. It is important to view the skin as an integral communicating part of the body and not just as the skin.
An overview of equine dermatoses characterized by scaling and crusting.
The Veterinary clinics of North America. Equine practice    April 1, 1995   Volume 11, Issue 1 43-51 doi: 10.1016/s0749-0739(17)30330-9
Fadok VA.Scaling and/or crusting are common clinical findings associated with equine skin diseases. Scaling and crusting may be associated with pruritic or nonpruritic dermatoses. This article focuses on those conditions that are usually nonpruritic in horses. They include the infectious dermatoses, the keratinization/seborrheic disorders, photosensitization, and the immunologic/inflammatory disorders, including pemphigus foliaceus, equine exfoliative eosinophilic dermatitis and stomatitis, and equine histiocytic dermatitis (sarcoidosis). Clinical signs that help differentiate the various disorders are...
Lipid metabolism in horses with hyperadrenocorticism.
Journal of the American Veterinary Medical Association    April 1, 1995   Volume 206, Issue 7 1010-1012 
van der Kolk JH, Wensing T, Kalsbeek HC, Breukink HJ.Lipid metabolism was studied in 21 horses with hyperadrenocorticism. To be included in the study, horses had to have histologic evidence of a pars intermedia adenoma found at necropsy (n = 9), a baseline ACTH concentration greater than 400 pg/ml (n = 6), or a plasma cortisol concentration 2 hours after i.v. administration of 25 IU of ACTH greater than 413 nmol/L (n = 16). Mean +/- SD baseline plasma cortisol concentration was 338 +/- 261 nmol/L (n = 20), mean +/- SD plasma insulin concentration was 97 +/- 54 microU/ml (n = 15), mean +/- SD plasma beta-hydroxybutyrate concentration was 1.8 +/- ...
A preliminary study of hyperextension of the carpal joint in the racing Thoroughbred.
New Zealand veterinary journal    April 1, 1995   Volume 43, Issue 2 83-84 doi: 10.1080/00480169.1995.35855
Deane NJ, Davies AS.A photographic study of the angles of 71 carpal joints of horses at the end of a race has shown that overextension of the joint is normal at this stage. Further study is needed to determine the factors which may influence hyperextension, and whether they are relevant to carpal injury.
Parasitic dermatoses that cause pruritus in horses.
The Veterinary clinics of North America. Equine practice    April 1, 1995   Volume 11, Issue 1 11-28 doi: 10.1016/s0749-0739(17)30328-0
Perris EE.Insect hypersensitivity is the most common cause of equine pruritus. It is a seasonal, highly pruritic dermatosis that is caused by the salivary antigens of biting insects. The most common insects are discussed in terms of the area of the horse affected, clinical signs, therapy, and preventative strategies.
Overview of equine pruritus.
The Veterinary clinics of North America. Equine practice    April 1, 1995   Volume 11, Issue 1 1-10 doi: 10.1016/s0749-0739(17)30327-9
Fadok VA.Pruritus is a common complaint associated with equine dermatoses. Self-mutilation results in alopecia, excoriations, scaling, and crusting; the aesthetic appearance of the horse is often ruined and the horse may be unfit for riding or showing. This article specifically addresses those pruritic dermatoses caused by allergies, including food allergy/intolerance, atopy and contact allergy, as well as by two ectoparasites, stick-tight fleas and rhabditic mange. The clinical signs, diagnostic tests, and treatment recommendations are discussed for each disorder. Insect hypersensitivity and pruritus ...
Detection of Salmonella enteritidis in equine feces using the polymerase chain reaction and genus-specific oligonucleotide primers. Cohen ND, Wallis DE, Neibergs HL, Hargis BM.Salmonella was identified in feces from horses, using the polymerase chain reaction (PCR) and genus-specific oligonucleotide primers. Feces from healthy horses were determined to be culture negative and PCR negative for Salmonella. Fecal samples were inoculated with known numbers of colony-forming units (CFU) of S. enteritidis. The fecal samples were enriched overnight in tetrathionate broth, and then DNA was extracted and amplified by PCR using genus-specific primers. Sensitivity of the assay extended to 10 degrees CFU Salmonella enteritidis/g feces; sensitivity of microbiologic culture with ...
Diversity of 16S rRNA genes of new Ehrlichia strains isolated from horses with clinical signs of Potomac horse fever.
International journal of systematic bacteriology    April 1, 1995   Volume 45, Issue 2 315-318 doi: 10.1099/00207713-45-2-315
Wen B, Rikihisa Y, Fuerst PA, Chaichanasiriwithaya W.Ehrlichia risticii is the causative agent of Potomac horse fever. Variations among the major antigens of different local E. risticii strains have been detected previously. To further assess genetic variability in this species or species complex, the sequences of the 16S rRNA genes of several isolates obtained from sick horses diagnosed as having Potomac horse fever were determined. The sequences of six isolates obtained from Ohio and three isolates obtained from Kentucky were amplified by PCR. Three groups of sequences were identified. The sequences of five of the Ohio isolates were identical ...
Oxytocin in mares: lack of evidence for oxytocin production by or action on preovulatory follicles.
Domestic animal endocrinology    April 1, 1995   Volume 12, Issue 2 133-142 doi: 10.1016/0739-7240(94)00015-s
Stock AE, Emeny RT, Sirois J, Fortune JE.It is not known whether the equine preovulatory follicle produces oxytocin or is a target tissue for oxytocin, as has been reported for other species, especially ruminants. Bovine granulosa cells secrete oxytocin, and oxytocin modulates the production of progesterone by granulosa cells in vitro. We examined whether oxytocin plays a comparable role in the equine preovulatory follicle. To test the hypothesis that the equine preovulatory follicle produces oxytocin during estrus and that its production increases in late estrus, preovulatory follicles were isolated during early (Days 1 to 2; n = 4)...
Relationship among seminal characteristics, fertility and suitability for semen preservation in draft stallions.
The Journal of veterinary medical science    April 1, 1995   Volume 57, Issue 2 225-229 doi: 10.1292/jvms.57.225
Torres-Boggino F, Sato K, Oka A, Kanno Y, Hochi S, Oguri N, Braun J.Seminal characteristics, fertility and the response to semen preservation (liquid storage and cryopreservation) were evaluated in 4 Draft stallions (Percheron 2, Breton 2). Seminal characteristics (gel-free volume, sperm concentration, sperm morphology, percentage of motile spermatozoa) were assessed in 5 ejaculates from each of the 4 stallions. The fertility of the stallions was calculated retrospectively as the accumulated pregnancy rate over 3 breeding seasons. Five ejaculates from each of the stallions were subjected to liquid storage at 5 degrees C. The percentage of motile spermatozoa (P...
Responsiveness of equine basilar artery to transmural nerve stimulation differs from that of porcine and bovine basilar arteries in vitro.
The Journal of veterinary medical science    April 1, 1995   Volume 57, Issue 2 365-366 doi: 10.1292/jvms.57.365
Miyamoto A, Kanda J, Nishio A.Transmural nerve stimulation (TNS) induced relaxations in porcine and bovine basilar arteries which were abolished by tetrodotoxin (TTX) and by L-nitro-arginine (LNAG). However, TNS induced contractions in equine basilar artery which were abolished by TTX and by guanethidine, but not by LNAG. These results suggest that the TNS-induced contractions of equine basilar arteries may be mediated by norepinephrine release.
[Susceptibility of bacterial isolates from the equine respiratory tract to trimethoprim, sulfadoxine, sulfadimethoxine and combinations of these compounds].
Tierarztliche Praxis    April 1, 1995   Volume 23, Issue 2 148-154 
Fey K, Schmid P.Using a broth microdilution technique, the in vitro susceptibility of bacterial isolates from the equine respiratory tract to trimethoprim, sulfadoxine, sulfadimethoxine, and combinations of these compounds was determined. The bacterial strains (n = 88) isolated recently from horses with respiratory symptoms belonged to the following species: Streptococcus equi subsp. zooepidemicus (n = 34), Streptococcus equi subsp. equi (n = 22), Staphylococcus aureus (n = 9), Klebsiella pneumoniae (n = 7), Rhodococcus equi (n = 4), Pseudomonas spp. (n = 3) and Escherichia coli (n = 3). In addition, two isol...
Treatment of olecranon bursitis in horses: 10 cases (1986-1993).
Journal of the American Veterinary Medical Association    April 1, 1995   Volume 206, Issue 7 1022-1026 
Honnas CM, Schumacher J, McClure SR, Crabill MR, Carter GK, Schmitz DG, Hoffman AG.Medical records of 10 horses with olecranon bursitis were reviewed to examine treatments, evaluate a technique for en bloc resection of the bursa in standing horses, and determine outcome of the horses after treatment. Before admission, 6 horses had been treated by needle aspiration of fluid from the mass, followed by injection of corticosteroids. Subsequent treatment for 2 of these 6 horses included open drainage and packing of the cavity with gauze soaked in 7% iodine solution. None resolved after these treatments. After admission to the hospital, 5 horses were treated medically and 5 were t...