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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Surgical management of small intestinal incarceration through the gastrosplenic ligament: 14 cases (1994-2006).
Journal of the American Veterinary Medical Association    October 17, 2007   Volume 231, Issue 8 1221-1224 doi: 10.2460/javma.231.8.1221
Jenei TM, García-López JM, Provost PJ, Kirker-Head CA.To determine prevalence, clinical findings, and long-term survival rate after surgery associated with incarceration of the small intestine through the gastrosplenic ligament (ISIGL) in horses. Methods: Retrospective case series. Methods: 14 horses with ISIGL. Methods: Medical records of horses with ISIGL examined between January 1994 and December 2006 were reviewed. Signalment, initial physical examination findings, results of abdominal fluid analysis, and clinical laboratory values were recorded, along with surgical findings, including segment of incarcerated intestine and surgical procedures...
Comments on eradication of strangles in equids.
Journal of the American Veterinary Medical Association    October 17, 2007   Volume 231, Issue 8 1196-1197 doi: 10.2460/javma.231.8.1196
Bender S.No abstract available
Safety and efficacy in geese of a PER.C6-based inactivated West Nile virus vaccine.
Vaccine    October 15, 2007   Volume 25, Issue 49 8338-8345 doi: 10.1016/j.vaccine.2007.09.055
Samina I, Havenga M, Koudstaal W, Khinich Y, Koldijk M, Malkinson M, Simanov M, Perl S, Gijsbers L, Weverling GJ, Uytdehaag F, Goudsmit J.Studies were performed with an inactivated vaccine against the mosquito-borne flavivirus, West Nile virus (WNV). The mammalian cell line, PER.C6, was selected as the platform for WNV growth since both the neurovirulent strains NY99 and ISR98 that cause epidemics in humans and high mortality in geese, respectively, could be propagated to high titers (10(9) to 10(10)TCID(50)/ml) on these cells. Based on the high DNA homology of the WNV envelope (E) protein and non-structural protein 5 (NS5), and identical neurovirulence in mice and geese, we concluded that NY99 and ISR98 viruses are closely rela...
Diagnostic imaging of the equine tarsal region using radiography and ultrasonography. Part 2: bony disorders.
Veterinary journal (London, England : 1997)    October 15, 2007   Volume 179, Issue 2 188-196 doi: 10.1016/j.tvjl.2007.08.025
Vanderperren K, Raes E, Bree HV, Saunders JH.This is the second part of a two-part review of the structures and disorders of the equine tarsus. In this part the bones of the tarsal region are considered and the technical aspects of taking radiographic, ultrasonographic and scintigraphic images of the different lesions are addressed. The diagnostic use of arthroscopy, computed tomography and magnetic resonance are discussed. In current clinical practice the most frequently used combination to arrive at a diagnosis is still radiography and ultrasonography.
Evaluation of serum osteocalcin and CTX-I in Ardenner horses with special reference to juvenile interphalangeal joint disease.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine    October 13, 2007   Volume 54, Issue 9 458-463 doi: 10.1111/j.1439-0442.2007.00951.x
Pastoret V, Carstanjen B, Lejeune JP, Farnir F, Remy B, Reginster JY, Serteyn D, Gabriel A.The first aim of this study was to establish a profile of age-related normal serum concentrations of osteocalcin (OC) in Ardenner horses. For this first part, blood samples from 49 healthy Ardenner horses were collected. The second aim was to study two biochemical markers of bone metabolism, OC and a carboxy-terminal cross-linking telopeptide of type I collagen (CTX-I), in 30 young Ardenner horses during 1 year. Amongst them, 17 showed lesions of juvenile degenerative joint disease in the distal forelimbs. A specific radioimmunoassay for equine OC was used to measure the serum concentration of...
Horse birth.
Midwifery today with international midwife    October 12, 2007   Issue 83 34 
Makela C.No abstract available
Equine umbilical cord blood contains a population of stem cells that express Oct4 and differentiate into mesodermal and endodermal cell types.
Journal of cellular physiology    October 12, 2007   Volume 215, Issue 2 329-336 doi: 10.1002/jcp.21312
Reed SA, Johnson SE.Mesenchymal stem cells (MSCs) offer promise as therapeutic aids in the repair of tendon, ligament, and bone damage suffered by sport horses. The objective of the study was to identify and characterize stem-like cells from newborn foal umbilical cord blood (UCB). UCB was collected and MSC isolated using human reagents. The cells exhibit a fibroblast-like morphology and express the stem cell markers Oct4, SSEA-1, Tra1-60 and Tra1-81. Culture of the cells in tissue-specific differentiation media leads to the formation of cell types characteristic of mesodermal and endodermal origins. Chondrogenic...
Safer birth in a barn?
Midwifery today with international midwife    October 12, 2007   Issue 83 32-33 
Barbeau B.No abstract available
Trypanosoma evansi: molecular homogeneity as inferred by phenetical analysis of ribosomal internal transcribed spacers DNA of an eclectic parasite.
Experimental parasitology    October 12, 2007   Volume 118, Issue 3 402-407 doi: 10.1016/j.exppara.2007.10.003
de Oliveira Lima AN, da Silva Santos S, Herrera HM, Gama C, Cupolillo E, Jansen AM, Fernandes O.The protozoan Trypanosoma evansi is described as presenting high morphological and genetic similarities among the isolates despite its biological heterogeneity and wide geographical distribution. PCR amplification of the internal transcribed spacers of the ribosomal gene in combination with the coding region of the 5.8S ribosomal subunit further submitted to restriction enzymes digestion were carried out in DNAs extracted from 41 T. evansi strains isolated from horses, dogs, coatis and capybaras from two distinct regions of the Brazilian Pantanal. We also used one T. evansi isolate from Africa...
Surgical management and outcome of a type-III Salter-Harris fracture of the frontal plane of the distal radial physis in a foal.
New Zealand veterinary journal    October 12, 2007   Volume 55, Issue 5 248-252 doi: 10.1080/00480169.2007.36777
Rutherford DJ, Textor J, Fretz PB.A 4-week-old Thoroughbred filly presented with lameness of acute, severe onset of the left foreleg (LF) of 3 days' duration. Results: Diffuse swelling was present around the distal radius and carpus of the LF. Carpal varus that could be reduced manually was present. Radiographs revealed an intra- articular frontal-plane fracture in the distal radial epiphysis, which continued cranially through the distal radial physis (DRP). The lateral aspect of the DRP was wider than expected. Latero-medial carpal instability was resolved by placement of a lag screw from the dorsal midline through the epiphy...
Heterophile antibodies in horse plasma interfering in an enzyme-linked immunosorbent assay.
Veterinary research communications    October 10, 2007   Volume 31 Suppl 1 165-168 doi: 10.1007/s11259-007-0023-6
Borromeo V, Berrini A, Gaggioli D, Secchi C.No abstract available
Incidence of myiasis in Panama during the eradication of Cochliomyia hominivorax (Coquerel 1858, Diptera: Calliphoridae) (2002-2005).
Memorias do Instituto Oswaldo Cruz    October 10, 2007   Volume 102, Issue 6 675-679 doi: 10.1590/s0074-02762007005000074
Bermúdez SE, Espinosa JD, Cielo AB, Clavel F, Subía J, Barrios S, Medianero E.We present the results of a study on myiasis in Panama during the first years of a Cochliomyia hominivorax eradication program (1998-2005), with the aim of investigating the behavior of the flies that produce myiasis in animals and human beings. The hosts that registered positive for myiasis were cattle (46.4%), dogs (15.3%), humans (14.7%), birds (12%), pigs (6%), horses (4%), and sheep (1%). Six fly species caused myiasis: Dermatobia hominis (58%), Phaenicia spp. (20%), Cochliomyia macellaria (19%), Chrysomya rufifacies (0.4%), and maggots of unidentified species belonging to the Sarcophagid...
Proteinuria, GGT index and fractional clearance of electrolytes in exercising athletic horses.
Veterinary research communications    October 10, 2007   Volume 31 Suppl 1 339-342 doi: 10.1007/s11259-0061-0
Scarpa P, Di Fabio V, Ramirez C, Baggiani L, Ferro E.No abstract available
Treatment of chronic atrial fibrillation in the horse with flecainide: personal observation.
Veterinary research communications    October 10, 2007   Volume 31 Suppl 1 273-275 doi: 10.1007/s11259-007-0045-0
Birettoni F, Porciello F, Rishniw M, della Rocca G, Di Salvo A, Sgorbini M.No abstract available
Sero-epidemiological study of Borna disease virus infection in the Italian equine population.
Veterinary research communications    October 10, 2007   Volume 31 Suppl 1 245-248 doi: 10.1007/s11259-007-0016-5
Pisoni G, Nativi D, Bronzo V, Codazza D.No abstract available
The use of alpha-2 agonists in the equine practice: comparison between three molecules.
Veterinary research communications    October 10, 2007   Volume 31 Suppl 1 309-312 doi: 10.1007/s11259-007-0103-7
Nannarone S, Gialletti R, Veschini I, Bufalari A, Moriconi F.Alpha-2 agonists are synthetic drugs which cause sedation, analgesia and myorelaxation due to their interaction with alpha-2 adrenoreceptors, widely distributed throughout bodily systems. Because of these actions such drugs are generally used in veterinary practice: to tranquilize animals (pharmacologic restraint) for the safety of both veterinar-ians and cooperators. Such properties facilitate diagnostic examinations or minimally in-vasive and poorly painful surgical procedures, as well as limiting stress factors to the patients. The aim of this study is to find out the minor dosage able to m...
Equine bronchoalveolar lavage cytokines in the development of recurrent airway obstruction.
Veterinary research communications    October 10, 2007   Volume 31 Suppl 1 313-316 doi: 10.1007/s11259-007-0055-y
Pietra M, Peli A, Bonato A, Ducci A, Cinotti S.No abstract available
Anesthesia in Caspian ponies.
Veterinary anaesthesia and analgesia    October 10, 2007   Volume 35, Issue 3 237-241 doi: 10.1111/j.1467-2995.2007.00366.x
Seddighi MR, Mohri M.To evaluate some of the clinical and laboratory parameters following diazepam-acepromazine, thiopental, and halothane anesthesia in Caspian ponies. Methods: Prospective experimental trial. Methods: Six healthy Caspian ponies of both sexes, aged 11 +/- 3 years and weighing 318 +/- 71 kg. Methods: The ponies were pre-medicated with diazepam (0.2 mg kg(-1)) and acepromazine (0.05 mg kg(-1)) IV. Sodium thiopental 5% was administered IV, 10 minutes later and anesthesia was maintained with halothane in oxygen for 1 hour. Heart and respiratory rates, mean arterial blood pressure, cardiac rhythm, and ...
A comparison of equine and bovine sera as sources of lipopolysaccharide-binding protein activity in equine monocytes incubated with lipopolysaccharide.
Veterinary immunology and immunopathology    October 10, 2007   Volume 121, Issue 3-4 275-280 doi: 10.1016/j.vetimm.2007.10.002
Figueiredo MD, Salter CE, Hurley DJ, Moore JN.Lipopolysaccharide-binding protein (LBP) is an acute phase protein that binds the lipid A moiety of lipopolysaccharide (LPS) and transfers LPS monomers to soluble CD14 in plasma or membrane bound CD14 on mononuclear phagocytes. The result of these interactions is activation of the TLR4 receptor complex, and the synthesis and release of inflammatory mediators. Inclusion of LBP in cellular assays increases the sensitivity of cells expressing CD14 to LPS. Therefore, the objectives of this study were to (1) compare differentially treated sera from cattle and horses as sources of LBP activity using...
Haemodynamic effects in healthy horses treated with an ACE-inhibitor (Ramipril).
Veterinary research communications    October 10, 2007   Volume 31 Suppl 1 297-299 doi: 10.1007/s11259-007-0051-2
Luciani A, Civitella C, Santori D, Sconza S, Guglielmini C.No abstract available
Cell therapy for tendon repair in horses: an experimental study.
Veterinary research communications    October 10, 2007   Volume 31 Suppl 1 281-283 doi: 10.1007/s11259-007-0047-y
Crovace A, Lacitignola L, De Siena R, Rossi G, Francioso E.No abstract available
Ketamine levels in plasma and red blood cells after intravenous administration in the horse.
Veterinary research communications    October 10, 2007   Volume 31 Suppl 1 327-329 doi: 10.1007/s11259-007-0105-5
Roncada P, Romagnoli N, Spadari A, di Fabio P, Nigro V, Zaghini A.No abstract available
Suspension of bone marrow-derived undifferentiated mesenchymal stromal cells for repair of superficial digital flexor tendon in race horses.
Tissue engineering    October 9, 2007   Volume 13, Issue 12 2949-2955 doi: 10.1089/ten.2007.0108
Pacini S, Spinabella S, Trombi L, Fazzi R, Galimberti S, Dini F, Carlucci F, Petrini M.It has been proven that mesenchymal stromal cells (MSCs) can differentiate into tenocytes. Attempts to repair tendon lesions have been performed, mainly using scaffold carriers in experimental settings. In this article, we describe the clinical use of undifferentiated MSCs in racehorses. Significant clinical recovery was achieved in 9 of 11 horses evaluated using ultrasound analysis and their ability to return to racing. Our results show that the suspension of a small number of undifferentiated MSCs may be sufficient to repair damaged tendons without the use of scaffold support. Ultrasound sca...
Assessing equine anxiety-related parameters using an isolation test in combination with a questionnaire survey.
The Journal of veterinary medical science    October 6, 2007   Volume 69, Issue 9 945-950 doi: 10.1292/jvms.69.945
Momozawa Y, Terada M, Sato F, Kikusui T, Takeuchi Y, Kusunose R, Mori Y.The aim of the study was to determine parameters reflecting equine anxiety trait by comparing results obtained in a behavior test and an anxiety score assessed by familiar caretakers in response to a questionnaire. In the behavior test, horses were individually led into a novel room by their caretakers and loosely tethered to decrease excessive movement using the common cross-tying technique with two leads and breakable plastic cords. The horses initially remained with their caretaker for 2 min; the caretaker then left and the subject animal was left alone for 2 min. The latency to break the p...
What is your diagnosis? Occipitoatlantoaxial malformation.
Journal of the American Veterinary Medical Association    October 6, 2007   Volume 231, Issue 7 1033-1034 doi: 10.2460/javma.231.7.1033
Bell S, Detweiler D, Benak J, Pusterla N.No abstract available
Digestive enzyme concentrations and activities in healthy pancreatic tissue of horses.
American journal of veterinary research    October 6, 2007   Volume 68, Issue 10 1070-1072 doi: 10.2460/ajvr.68.10.1070
Lorenzo-Figueras M, Morisset SM, Morisset J, Lainé J, Merritt AM.To measure concentrations and activities of major digestive enzymes in healthy equine pancreatic tissue. Methods: 7 adult horses with normal pancreatic tissues. Methods: Small pieces of pancreatic tissue were collected immediately after euthanasia, immersed in liquid nitrogen, and maintained at -80 degrees C until analyzed. Concentrations and activities of amylase, lipase, chymotrypsin, trypsin, and elastase were determined by use of a microtiter technique. Relative pancreatic protein concentrations were determined by use of bovine serum albumin as the standard. Pancreatic DNA was extracted an...
Biochemical and genetic evaluation of the role of AMP-activated protein kinase in polysaccharide storage myopathy in Quarter Horses.
American journal of veterinary research    October 6, 2007   Volume 68, Issue 10 1079-1084 doi: 10.2460/ajvr.68.10.1079
Dranchak PK, Leiper FC, Valberg SJ, Piercy RJ, Carling D, McCue ME, Mickelson JR.To evaluate whether biochemical or genetic alterations in AMP-activated protein kinase (AMPK) play a role in the development of polysaccharide storage myopathy (PSSM) in Quarter Horses. Methods: 30 PSSM-affected and 30 unaffected (control) Quarter Horses. Methods: By use of an established peptide phosphotransfer assay, basal and maximal AMPK activities were measured in muscle biopsy samples obtained from 6 PSSM-affected and 6 control horses. In 24 PSSM-affected and 24 control horses, microsatellite markers identified from the chromosomal locations of all 7 AMPK subunit genes were genotyped wit...
Pharmacokinetics of gallium maltolate after intragastric administration in neonatal foals.
American journal of veterinary research    October 6, 2007   Volume 68, Issue 10 1041-1044 doi: 10.2460/ajvr.68.10.1041
Martens RJ, Mealey K, Cohen ND, Harrington JR, Chaffin MK, Taylor RJ, Bernstein LR.To determine the pharmacokinetics of gallium maltolate (GaM) after intragastric administration in healthy foals. Methods: 6 healthy neonatal foals. Methods: Each foal received GaM (20 mg/kg) by intragastric administration. Blood samples were obtained before (time 0) and at 0.25, 0.5, 1, 2, 4, 8, 12, 24, 36, and 48 hours after GaM administration for determination of serum gallium concentrations by use of inductively coupled plasma mass spectroscopy. Results: Mean +/- SD pharmacokinetic variables were as follows: peak serum gallium concentration, 1,079 +/- 311 ng/mL; time to peak serum concentra...
Pharmacokinetics of voriconazole following intravenous and oral administration and body fluid concentrations of voriconazole following repeated oral administration in horses.
American journal of veterinary research    October 6, 2007   Volume 68, Issue 10 1115-1121 doi: 10.2460/ajvr.68.10.1115
Colitz CM, Latimer FG, Cheng H, Chan KK, Reed SM, Pennick GJ.To determine the pharmacokinetics of voriconazole following IV and PO administration and assess the distribution of voriconazole into body fluids following repeated PO administration in horses. Methods: 6 clinically normal adult horses. Methods: All horses received voriconazole (10 mg/kg) IV and PO (2-week interval between treatments). Plasma voriconazole concentrations were determined prior to and at intervals following administration. Subsequently, voriconazole was administered PO (3 mg/kg) twice daily for 10 days to all horses; plasma, synovial fluid, CSF, urine, and preocular tear film con...
Isolation and characterization of bone marrow-derived equine mesenchymal stem cells.
American journal of veterinary research    October 6, 2007   Volume 68, Issue 10 1095-1105 doi: 10.2460/ajvr.68.10.1095
Arnhold SJ, Goletz I, Klein H, Stumpf G, Beluche LA, Rohde C, Addicks K, Litzke LF.To isolate and characterize bone marrow-derived equine mesenchymal stem cells (MSCs) for possible future therapeutic applications in horses. Methods: Equine MSCs were isolated from bone marrow aspirates obtained from the sternum of 30 donor horses. Methods: Cells were cultured in medium (alpha-minimum essential medium) with a fetal calf serum content of 20%. Equine MSC features were analyzed to determine selfrenewing and differentiation capacity. For potential therapeutic applications, the migratory potential of equine MSCs was determined. An adenoviral vector was used to determine the transdu...