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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Effects of continuous rate intravenous infusion of butorphanol on physiologic and outcome variables in horses after celiotomy.
Journal of veterinary internal medicine    August 24, 2004   Volume 18, Issue 4 555-563 doi: 10.1892/0891-6640(2004)182.0.co;2
Sellon DC, Roberts MC, Blikslager AT, Ulibarri C, Papich MG.A randomized, controlled, blinded clinical trial was performed to determine whether butorphanol administered by continuous rate infusion (CRI) for 24 hours after abdominal surgery would decrease pain and surgical stress responses and improve recovery in horses. Thirty-one horses undergoing exploratory celiotomy for abdominal pain were randomly assigned to receive butorphanol CRI (13 microg/kg/h for 24 hours after surgery; treatment) or isotonic saline (control). All horses received flunixin meglumine (1.1 mg/kg IV q12h). There were no significant differences between treatment and control horse...
Retrospective comparison of azithromycin, clarithromycin, and erythromycin for the treatment of foals with Rhodococcus equi pneumonia.
Journal of veterinary internal medicine    August 24, 2004   Volume 18, Issue 4 568-573 doi: 10.1892/0891-6640(2004)18<568:rcoaca>2.0.co;2
Giguère S, Jacks S, Roberts GD, Hernandez J, Long MT, Ellis C.The objective of this retrospective study was to compare the efficacy of azithromycin-rifampin, clarithromycin-rifampin, and erythromycin-rifampin for the treatment of pneumonia caused by Rhodococcus equi in foals. Eighty-one foals with naturally acquired pneumonia caused by R. equi were included in the study. Information on age, sex, breed, physical examination findings, laboratory testing, and thoracic radiography was abstracted from each medical record. Foals were divided in 3 groups based on the antimicrobial agent selected for therapy. Short-term (discharge from the hospital) and long-ter...
The diagnostic and prognostic value of alkaline phosphatase activity in serum and peritoneal fluid from horses with acute colic.
Journal of veterinary internal medicine    August 24, 2004   Volume 18, Issue 4 564-567 doi: 10.1892/0891-6640(2004)182.0.co;2
Saulez MN, Cebra CK, Tornquist SJ.Alkaline phosphatase (ALP) is an enzyme present in intestinal mucosa, bile, bone, and renal tubule cells. We sought to assess the diagnostic and prognostic relationships of total ALP (ALPt) activity and that of intestine-derived ALP (ALPi) in serum and peritoneal fluid of 126 horses with colic. ALPt and ALPi activities were measured in both serum and peritoneal fluid by using both standard and L-phenylalanine-based buffers, respectively. Neither ALPt nor ALPi activity were useful in classifying type or severity of intestinal damage. ALPt and ALPi activities in peritoneal fluid were lowest in h...
Isolation of methicillin-resistant Staphylococcus aureus from the environment in a veterinary teaching hospital.
Journal of veterinary internal medicine    August 24, 2004   Volume 18, Issue 4 468-470 doi: 10.1892/0891-6640(2004)182.0.co;2
Weese JS, DaCosta T, Button L, Goth K, Ethier M, Boehnke K.After recognition of a cluster of methicillin-resistant Staphylococcus aureus (MRSA) infection in horses and humans at the Ontario Veterinary College Veterinary Teaching Hospital, environmental contamination with MRSA was evaluated. A total of 260 environmental surfaces were sampled during periods when MRSA-infected horses were hospitalized, and MRSA was isolated from 25/260 sites (9.6%). The most commonly contaminated sites were stalls housing MRSA-positive horses, but other stalls, medical equipment, personal items, and equine restraint devices also were contaminated. The role of the environ...
Short-duration exercise and confinement alters bone mineral content and shape in weanling horses.
Journal of animal science    August 21, 2004   Volume 82, Issue 8 2313-2320 doi: 10.2527/2004.8282313x
Hiney KM, Nielsen BD, Rosenstein D.The hypothesis that short-duration exercise may ameliorate the decrease in bone mass observed with confinement was investigated with 18 quarter horses (nine colts and nine fillies) weaned at 4 mo of age and placed into box stalls. After a 5-wk adjustment period, individuals were grouped by age and weight, and then divided randomly into three treatment groups: 1) group housed; 2) confined with no exercise; and 3) confined with exercise. The confined and exercised groups were housed in 3.7 m x 3.7 m box stalls for the 56-d duration of the trial. The exercised group was sprinted 82 m/d, 5 d/wk, i...
Idiopathic prolapse of 1 uterine horn in a yearling filly.
The Canadian veterinary journal = La revue veterinaire canadienne    August 20, 2004   Volume 45, Issue 7 602-604 
Schambourg MA, Spriet M, Piccot-Crézollet C, Vaillancourt D.A yearling filly was presented for protrusion of a mass at the vulvar margins. A diagnosis of prolapse of the right uterine horn was made after vaginoscopy, transrectal palpation, and ultrasonography. It was confirmed later by biopsy of the tissue. Recovery was uneventful after easy replacement of the uterine horn. Une pouliche yearling fut présentée pour la protrusion d’une masse au pourtour de la vulve. Un diagnostic de prolapsus de la corne utérine droite fut établi à la suite de la vaginoscopie, de la palpation transrectale et de l’échographie. Le diagnostic fut confirmé par la...
The association between heart rate, heart rate variability, endocrine and behavioural pain measures in horses suffering from laminitis.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine    August 19, 2004   Volume 51, Issue 5 218-225 doi: 10.1111/j.1439-0442.2004.00627.x
Rietmann TR, Staᆲher M, Bernasconi P, Auer JA, Weishaupt MA.The objective of this study was to compare the stress response of horses suffering from laminitis after short- and long-term treatment with the intent to evaluate power spectral analysis of heart rate variability (HRV) for pain monitoring. Data were collected from 19 horses with acute or chronic exacerbating laminitis without known primary disease before and after treatment with non-steroidal anti-inflammatory drugs (NSAID). Recordings were carried out the day after admission to the equine hospital. Measurements were repeated on day 7 of the treatment. The recorded parameters included a clinic...
In-vitro contraction of the equine aortic valve.
The Journal of heart valve disease    August 18, 2004   Volume 13, Issue 4 593-599 
Bowen IM, Marr CM, Chester AH, Wheeler-Jones CP, Elliott J.The equine aortic valve is subject to non-inflammatory degenerative changes, associated with aortic valvular regurgitation (AR). This disease shares pathological and epidemiological features with AR in humans, and may serve as a useful model to study in-vitro functional responses associated with aging and disease. The study aim was to determine the contractile properties of the normal equine aortic valve. Methods: The contractile responses of equine aortic valves to angiotensin II, the thromboxane-mimetic U44069, endothelin-1, 5-hydroxytryptamine and the alpha-adrenoceptor agonists medetomidin...
The use of porcine small intestinal submucosa for the repair of full-thickness corneal defects in dogs, cats and horses.
Veterinary ophthalmology    August 18, 2004   Volume 7, Issue 5 352-359 doi: 10.1111/j.1463-5224.2004.04055.x
Bussieres M, Krohne SG, Stiles J, Townsend WM.To evaluate the efficacy of using a porcine small intestinal submucosa (SIS) graft covered by a conjunctival flap for the surgical repair of full-thickness corneal wounds in dogs, cats and horses. Methods: All records dating from August 1999 to February 2003 from Purdue University Veterinary Teaching Hospital of patients that had undergone ophthalmic surgical procedures and received a SIS corneal graft for a full-thickness lesion were reviewed. Fifteen cases were identified including six dogs, two cats and seven horses. Requirements for inclusion in this study were that SIS was used as a corne...
Rodeo docs hope to lasso recognition.
CMAJ : Canadian Medical Association journal = journal de l\'Association medicale canadienne    August 18, 2004   Volume 171, Issue 4 320 doi: 10.1503/cmaj.1041148
O'Meara D.No abstract available
Use of topical mitomycin C in myoplasty of the medial rectus muscle of rabbits.
Veterinary ophthalmology    August 18, 2004   Volume 7, Issue 5 335-342 doi: 10.1111/j.1463-5224.2004.04026.x
Mamede FV, Laus JL, Cabral VP, Vicenti FA, Barbieri-Neto J.To possibly reduce postoperative adhesions that occur after ocular myoplasties, we investigated the topical effects of 0.04% mitomycin C on the repaired areas of the medial rectus muscle using an equine renal capsule preserved in 98% glycerin for reinforcement of the sutures. Twenty-four rabbits, divided into two groups of 12 animals each [untreated (control) and treated group (MMC)], were submitted to surgical rupture of the medial rectus muscle of one eye and repair of the defect 24 h later with sutures and an equine renal capsule. Post-operative prophylactic treatment of the two groups cons...
Adaptive immunity is the primary force driving selection of equine infectious anemia virus envelope SU variants during acute infection.
Journal of virology    August 17, 2004   Volume 78, Issue 17 9295-9305 doi: 10.1128/JVI.78.17.9295-9305.2004
Mealey RH, Leib SR, Pownder SL, McGuire TC.Equine infectious anemia virus (EIAV) is a lentivirus that causes persistent infection in horses. The appearance of antigenically distinct viral variants during recurrent viremic episodes is thought to be due to adaptive immune selection pressure. To test this hypothesis, we evaluated envelope SU cloned sequences from five severe combined immunodeficient (SCID) foals infected with EIAV. Within the SU hypervariable V3 region, 8.5% of the clones had amino acid changes, and 6.4% had amino acid changes within the known cytotoxic T lymphocyte (CTL) epitope Env-RW12. Of all the SU clones, only 3.1% ...
Equine congenital papilloma: pathological findings and results of papillomavirus immunohistochemistry in five cases.
Veterinary dermatology    August 13, 2004   Volume 15, Issue 4 240-244 doi: 10.1111/j.1365-3164.2004.00395.x
White KS, Fuji RN, Valentine BA, Bildfell RJ.Abstract Congenital cutaneous papillomas were identified in five foals. Age at diagnosis ranged from 305 days' gestation to 2 days of age. Breeds were thoroughbred (2), standard-bred (1), warmblood (1) and paint (1). Two were female, one was male and the gender of two cases was not specified. Masses were pedunculated with a roughened, wart-like (verrucous) or a smoother, cauliflower-like surface. Masses occurred as single lesions on the forelimb, lip and face, or as multiple lesions on the trunk. Histological features included relatively uniform epidermal papillary hyperplasia with variable me...
Hereditary equine regional dermal asthenia (“hyperelastosis cutis”) in 50 horses: clinical, histological, immunohistological and ultrastructural findings.
Veterinary dermatology    August 13, 2004   Volume 15, Issue 4 207-217 doi: 10.1111/j.1365-3164.2004.00402.x
White SD, Affolter VK, Bannasch DL, Schultheiss PC, Hamar DW, Chapman PL, Naydan D, Spier SJ, Rosychuk RA, Rees C, Veneklasen GO, Martin A, Bevier D....Data on fifty horses with hereditary equine regional dermal asthenia (HERDA; "hyperelastosis cutis") were collected on clinical, histopathological, ultrastructural and immunohistological findings. All horses were Quarter horses or of Quarter horse ancestry. Pedigree evaluation strongly supported an autosomal recessive mode of inheritance. The most common lesions were seromas/haematomas, open wounds, sloughing skin, and loose, easily tented skin that did not return to its initial position. Definitive diagnosis could not be made via histopathology, although the presence of tightly grouped thin a...
Equine abortion and premature birth associated with Cellulosimicrobium cellulans infection. Bolin DC, Donahue JM, Vickers ML, Giles RC, Harrison L, Jackson C, Poonacha KB, Roberts JE, Sebastian MM, Sells SE, Tramontin R, Williams NM.During the 2002 and 2003 foaling seasons, Cellulosimicrobium (Cellumonas) cellulans (formerly Oerskovia xanthineolytica) was the principal microorganism isolated from fetal tissues or placentas from cases of equine abortion, premature birth, and term pregnancies. Significant pathologic findings included chronic placentitis and pyogranulomatous pneumonia. In addition, microscopic and macroscopic alterations in the allantochorion from 4 of 7 cases of placentitis were similar to those caused by Crossiella equi and other nocardioform bacteria. This report confirms a causative role of C. cellulans ...
Scanning electron microscopy of the endometrium of mares infused with gentamicin. Al-Bagdadi FK, Eilts BE, Richardson GF.Scanning electron microscopy (SEM) was used to study the endometrium of nine 1-year-old thoroughbred mares after twice intrauterine infusions of gentamicin, on 2 consecutive days. Five mares were infused on 2 consecutive days with 40 ml gentamicin (50 mg/ml) mixed with 80 ml of normal saline. Four mares served as controls and were infused with 120 ml of saline on 2 consecutive days. Endometrial biopsies were obtained from all mares 3 days after the second intrauterine infusion. Each biopsy was processed for SEM by standard methods. The endometrial epithelium of the gentamicin-infused mares had...
Alopecia areata with lymphocytic mural folliculitis affecting the isthmus in a thoroughbred mare.
Veterinary dermatology    August 13, 2004   Volume 15, Issue 4 260-265 doi: 10.1111/j.1365-3164.2004.00392.x
Colombo S, Keen JA, Brownstein DG, Rhind SM, McGorum BC, Hill PB.A 13-year-old, thoroughbred mare was presented with an 8-year history of multifocal, generalized, noninflammatory alopecia and a 3-month history of alopecia, erythema and scaling of the white star on the forehead and muzzle. Histopathological examination of biopsy samples from multiple sites on the body (mane, neck, shoulder, flank and gluteal region) showed a subtle lymphocytic inflammatory infiltrate affecting and surrounding the anagen hair bulbs, consistent with a diagnosis of alopecia areata. The biopsy sample from the star on the forehead showed atrophic hair follicles with perifollicula...
Cytology of the normal and abnormal choroid plexi in selected domestic mammals, wildlife species, and man. Garma-Aviña A.A cytologic study of the choroid plexi of animals and humans was carried out using impression smears (imprints, imp) to understand better the cellular changes that occur in the cerebrospinal fluid in the case of disease. The samples, totaling 756 imp were from 11 dogs (239 imp), 10 horses (219 imp), 1 mule (23 imp), 3 cattle (69 imp), 1 sheep (19 imp), 2 pigs (39 imp), 1 deer (20 imp), 4 monkeys (22 imp), and 7 humans (106 imp). The samples came from individuals clinically free of neurologic disease, as well as from a few abnormal cases. Six of the 7 humans had no history of neurologic disease...
[Feline leishmaniasis: what’s the epidemiological role of the cat?].
Parassitologia    August 13, 2004   Volume 46, Issue 1-2 203-206 
Mancianti F.Feline leishmaniasis (FL) is a quite uncommon feature. Clinical disease has been described in cats since nineties begin. More than 40 reports in world literature have been referred, but the clinical cases have been only recently well defined. Most of the reports focus on infected cats living in endemic areas, even if, more recently FL due to Leishmania infantum was found in Sao Paulo State, in Brazil where autochthonous human or canine leishmaniasis cases have never reported. In Europe clinical cases of FL have been described from Portugal, France, Spain and Italy from 1996 to 2002. When a typ...
The effects of strain heterology on the epidemiology of equine influenza in a vaccinated population.
Proceedings. Biological sciences    August 13, 2004   Volume 271, Issue 1548 1547-1555 doi: 10.1098/rspb.2004.2766
Park AW, Wood JL, Daly JM, Newton JR, Glass K, Henley W, Mumford JA, Grenfell BT.We assess the effects of strain heterology (strains that are immunologically similar but not identical) on equine influenza in a vaccinated population. Using data relating to individual animals, for both homologous and heterologous vaccinees, we estimate distributions for the latent and infectious periods, quantify the risk of becoming infected in terms of the quantity of cross-reactive antibodies to a key surface protein of the virus (haemagglutinin) and estimate the probability of excreting virus (i.e. becoming infectious) given that infection has occurred. The data suggest that the infectio...
Lead in blood of urban Indian horses.
Veterinary and human toxicology    August 12, 2004   Volume 46, Issue 4 194-195 
Dey S, Dwivedi SK.A cross sectional study recorded the Lead (Pb) concentrations in blood from 288 horses in urban areas. Mean blood Pb concentration was estimated as 0.47 +/- 0.02 and 0.55 +/- 0.02 ppm in horses for industrial and highway-adjacent localities respectively. Mean blood Pb in horses from rural areas was 0.38 +/- 0.03 ppm. The mean Pb in forage samples from these horses was 36.96 +/- 6.23, 52.08 +/- 9.86 and 11.72 +/- 1.34 ppm in industrial, highway-adjacent and rural localities respectively. No overt signs of Pb toxicosis were seen in these animals
James Wardrop and equine recurrent uveitis.
Archives of ophthalmology (Chicago, Ill. : 1960)    August 11, 2004   Volume 122, Issue 8 1218-1223 doi: 10.1001/archopht.122.8.1218
Paglia DT, Miller PE, Dubielzig RR.James Wardrop should be remembered not only as one of the founders of ocular pathology but also for his contributions to the field of comparative ophthalmology. He described a "specific inflammation" that veterinarians today know as equine recurrent uveitis. As described by Wardrop in the 19th century, this condition is known today to eventually lead to blindness.
Gait analysis: technology looking for a place to happen?
Veterinary journal (London, England : 1997)    August 11, 2004   Volume 168, Issue 2 112-113 doi: 10.1016/S1090-0233(03)00137-0
Colborne GR.No abstract available
Viability of equine articular chondrocytes in alginate beads exposed to different oxygen tensions.
Veterinary journal (London, England : 1997)    August 11, 2004   Volume 168, Issue 2 167-173 doi: 10.1016/j.tvjl.2003.09.016
Schneider N, Lejeune JP, Deby C, Deby-Dupont GP, Serteyn D.Ischaemia and reperfusion are suspected to alter chondrocyte metabolism. Here, we studied the effects of three oxygen (O2) tensions on the viability of equine articular chondrocytes isolated from the cartilage of the distal interphalangeal joint of horses. Chondrocytes were cultured in alginate beads under 1%, 5% or 21% gas phase O2 concentration for 14 days, cellular growth kinetics were measured (n=6), and the cells were observed by light microscopy after staining for necrotic and apoptotic cell detection. For information about the metabolic status, the intracellular adenosine triphosphate (...
Step-wise dilution for removal of glycerol from fresh and cryopreserved equine spermatozoa.
Animal reproduction science    August 11, 2004   Volume 84, Issue 1-2 147-156 doi: 10.1016/j.anireprosci.2003.12.004
Wessel MT, Ball BA.Osmotic stress is an important component of the damage to spermatozoa during cryopreservation. Osmotic injury, due to hyperosmolar freezing extenders, changes in relative solute concentration in the extra cellular medium during freezing and differences in the relative permeabilities of penetrating cryoprotectants, such as glycerol, and water occur when cryopreserved spermatozoa are diluted into isosmotic media or when spermatozoa are placed in the female reproductive tract. The purpose of the study reported here was to evaluate the effect of step-wise dilution for the removal of the permeating...
Methanol as a cryoprotectant for equine embryos.
Theriogenology    August 4, 2004   Volume 62, Issue 6 1153-1159 doi: 10.1016/j.theriogenology.2003.12.026
Bass LD, Denniston DJ, Maclellan LJ, McCue PM, Seidel GE, Squires EL.Equine embryos (n=43) were recovered nonsurgically 7-8 days after ovulation and randomly assigned to be cryopreserved in one of two cryoprotectants: 48% (15M) methanol (n=22) or 10% (136 M) glycerol (n=21). Embryos (300-1000 microm) were measured at five intervals after exposure to glycerol (0, 2, 5, 10 and 15 min) or methanol (0, 15, 35, 75 and 10 min) to determine changes (%) in diameter over time (+/-S.D.). Embryos were loaded into 0.25-ml plastic straws, sealed, placed in a programmable cell freezer and cooled from room temperature (22 degrees C) to -6 degrees C. Straws were then seeded, h...
Evaluation of alternative cryoprotectants for preserving stallion spermatozoa.
Theriogenology    August 4, 2004   Volume 62, Issue 6 1056-1065 doi: 10.1016/j.theriogenology.2003.12.024
Squires EL, Keith SL, Graham JK.Although use of cryopreserved stallion spermatozoa is currently accepted by many breed registries, utilization of this technique remains limited due to poor fertility for some stallions. One reason for these results is osmotic stress that spermatozoa experiences when the cryoprotectant (glycerol) is added to the cells prior to freezing and removal from the cells after thawing. In an effort to minimize osmotic damage, alternative cryoprotectants, having lower molecular weights and greater membrane permeability than glycerol, were evaluated to determine their effectiveness for cryopreserving sta...
Amblyomma cajennense ticks induce immediate hypersensitivity in horses and donkeys.
Experimental & applied acarology    August 3, 2004   Volume 33, Issue 1-2 109-117 doi: 10.1023/b:appa.0000030016.33747.99
Szabó MP, Castagnolli KC, Santana DA, de Castro MB, Romano MA.Since host immune reaction to ticks interferes with tick-borne pathogen transmission, it is important to recognize naturally occurring tick-host immune relationships to better understand the epidemiology of such infectious diseases. Amblyomma cajennense is an important tick-borne disease vector in the Neotropical region and horses maintain it in domestic environments. In the present work intradermal testing of A. cajennense tick exposed horses and donkeys using crude tick antigens was used to evaluate the type of hypersensitivity induced by infestations. Animals sensitized by A. cajennense inf...
Right dorsal colitis in the horse: minireview and reports on three cases in Ireland.
Irish veterinary journal    August 1, 2004   Volume 57, Issue 8 467-473 doi: 10.1186/2046-0481-57-8-467
Galvin N, Dillon H, McGovern F.: Right dorsal colitis (RDC) is an ulcerative inflammatory bowel disorder of the horse that has been associated with the administration of non-steroidal anti-inflammatory drugs (NSAIDs), particularly in horses treated when dehydrated or toxaemic. The acute form of RDC may result in profuse diarrhoea, severe colic, dehydration, endotoxic shock and even death; the chronic form may be manifest by mild to moderate intermittent colic, ventral oedema and weight loss with or without diarrhoea. The most consistent laboratory findings are anaemia, hypoproteinaemia, hypoalbuminaemia and hypocalcaemia. M...
Androgen insensitivity syndrome in a thoroughbred mare (64, XY–testicular feminization).
The Canadian veterinary journal = La revue veterinaire canadienne    July 31, 2004   Volume 45, Issue 6 501-503 
Howden KJ.A Thoroughbred mare was presented for stallion-like behavior. Reproductive and ultrasonographic evaluation, testosterone assays, and karyotyping confirmed a diagnosis of androgen insensitivity syndrome (64, XY--testicular feminization). Surgery to remove abdominal testicles was successful in alleviating the behavioral abnormality. This condition is discussed with reference to the current literature. Une jument Thoroughbred a été présentée parce qu’elle avait un comportement d’étalon. Une évaluation reproductrice et échographique, des dosages de testostérone et un caryotypage ont c...