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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Effects of formaldehyde fixation on equine platelets using flow cytometric methods to evaluate markers of platelet activation.
American journal of veterinary research    June 14, 2002   Volume 63, Issue 6 840-844 doi: 10.2460/ajvr.2002.63.840
Kingston JK, Bayly WM, Sellon DC, Meyers KM, Wardrop KJ.To investigate the effects of formaldehyde fixation on equine platelets using flow cytometric methods to evaluate markers of platelet activation. Methods: Blood samples from 6 Thoroughbreds. Methods: The degree of fluorescence associated with binding of fluorescein isothiocyanate (FITC)-conjugated anti-human fibrinogen antibody and FITC-annexin V in unactivated and adenosine diphosphate (ADP)-, platelet activating factor (PAF)-, and A23187-activated platelet samples in unfixed and 0.5, 1.0, and 2.0% formaldehyde-fixed samples was assessed by use of flow cytometry. Results: In samples incubated...
Expression and coassociation of ERG1, KCNQ1, and KCNE1 potassium channel proteins in horse heart.
American journal of physiology. Heart and circulatory physiology    June 14, 2002   Volume 283, Issue 1 H126-H138 doi: 10.1152/ajpheart.00622.2001
Finley MR, Li Y, Hua F, Lillich J, Mitchell KE, Ganta S, Gilmour RF, Freeman LC.In dogs and in humans, potassium channels formed by ether-a-go-go-related gene 1 protein ERG1 (KCNH2) and KCNQ1 alpha-subunits, in association with KCNE beta-subunits, play a role in normal repolarization and may contribute to abnormal repolarization associated with long QT syndrome (LQTS). The molecular basis of repolarization in horse heart is unknown, although horses exhibit common cardiac arrhythmias and may receive drugs that induce LQTS. In horse heart, we have used immunoblotting and immunostaining to demonstrate the expression of ERG1, KCNQ1, KCNE1, and KCNE3 proteins and RT-PCR to det...
The isomeric metabolites of doxepin in equine serum and urine.
Journal of pharmaceutical and biomedical analysis    June 14, 2002   Volume 29, Issue 1-2 317-323 doi: 10.1016/s0731-7085(02)00069-9
Hagedorn HW, Meiser H, Zankl H, Schulz R.Due to its tranquilizing properties, the tricyclic antidepressant doxepin may be misused as a doping agent in competition horses. Therefore, efficient analytical procedures are required to detect this drug in samples submitted for doping control. To screen for parent doxepin in equine blood and urine, a less specific method has been accepted employing gas chromatography (GC) combined with electron impact (EI) mass spectrometry (MS). The aim of this study was identification of doxepin metabolites providing more specific MS data to verify positives resulting from screening. Thus, after a horse w...
Comparison of pharmacokinetic variables for two low-molecular-weight heparins after subcutaneous administration of a single dose to horses.
American journal of veterinary research    June 14, 2002   Volume 63, Issue 6 868-873 doi: 10.2460/ajvr.2002.63.868
Schwarzwald CC, Feige K, Wunderli-Allenspach H, Braun U.To determine pharmacokinetic variables and to evaluate the influence on clotting times after SC administration of single doses of dalteparin and enoxaparin to horses. Methods: 5 healthy adult horses. Methods: The study was designed as a 4-period crossover study. Each horse received a single SC injection of dalteparin (50 and 100 anti-Xa U/kg) and enoxaparin (40 and 80 anti-Xa U/kg). Plasma anti-Xa activities and clotting times were measured, and pharmacokinetic variables were determined. Absolute and relative maximal prolongation of clotting times was calculated, and correlation between plasma...
[Implantation of transponders at the bottom of the ear in equines].
Berliner und Munchener tierarztliche Wochenschrift    June 13, 2002   Volume 115, Issue 5-6 161-166 
Mader Ch, Geisel O, Gerhards H, Hermanns W.In the present work transponders of 2 identification systems have been implanted on an exactly defined site at the bottom of the ear on 28 horses. The Backhome system is easier to handle and less complicated than the trovan system since it is smaller and handier. The hemorrhages that had occurred after the injection were mild at 17 animals and moderate at 4 animals. Inflame changes at the injection site post application were limited to minor swellings (n = 3) and minor pain (n = 6). The interrogator's scope of the two transponder systems is different. The interrogator's scope of the trovan tra...
Prevalence of equine herpesvirus types 2 and 5 in horse populations by using type-specific PCR assays.
Veterinary research    June 12, 2002   Volume 33, Issue 3 251-259 doi: 10.1051/vetres:2002013
Nordengrahn A, Merza M, Ros C, Lindholmc A, Palfl V, Hannant D, Belák S.Equineherpesvirustypes 2 and 5 (EHV-2andEHV-5)have a rather unclearpathogenicity and distribution within the equid population. In order to gain more information on the prevalence of these two viruses, type-specific PCR assays were developed to detect viral DNA in nasal specimens and in peripheral blood leukocytes (PBLs) of adult horses and foals from various regions of Europe, i.e. Sweden, Hungary and the United Kingdom. In adult horses, the prevalence of EHV-2 in PBLs was up to 68% in Sweden and 71% in the United Kingdom. EHV-2 DNA was detected in the PBLs from all the foals tested in all cou...
Capacitation and acrosomal exocytosis are enhanced by incubation of stallion spermatozoa in a commercial semen extender.
Theriogenology    June 11, 2002   Volume 57, Issue 5 1493-1501 doi: 10.1016/s0093-691x(02)00659-3
Pommer AC, Linfor JJ, Meyers SA.Preserved stallion semen often has decreased spermatozoal motility and fertility that can vary significantly between individual stallions. It is not known whether the medium used for extending equine sperm contributes to these decreases by inducing premature capacitation during storage. If spermatozoa undergo capacitation or acrosome reaction prior to insemination, this could result in a diminished capacity to penetrate the cumulus mass and fertilize the egg. We hypothesized that skim milk-based semen extenders, similar to those used in cooled storage, stabilize sperm membranes and prolong spe...
Coronary band dystrophy in two horses.
The Veterinary record    June 11, 2002   Volume 150, Issue 21 665-668 doi: 10.1136/vr.150.21.665
Menzies-Gow NJ, Bond R, Patterson-Kane JC, McGowan CM.Two mature large-breed horses with coronary band dystrophy and chorioptic mange are described. They both had clinical signs of coronary band scaling and crusting but were not lame. Coronary band dystrophy can be differentiated from similar clinical conditions on the basis of the histological appearance of skin biopsy specimens, and by the exclusion of other possible disease processes. Its aetiology is uncertain, but probably involves a localised defect of keratinisation affecting the specialised epithelium of the coronary band.
Isolation of Salem virus, a novel equine paramyxovirus, and assessment of its etiologic role in a disease outbreak.
Veterinary microbiology    June 8, 2002   Volume 87, Issue 3 205-212 doi: 10.1016/s0378-1135(02)00067-6
Glaser AL, Renshaw RW, Trock SC, Brady RC, Dubovi EJ.Salem virus (SalV) is a recently identified equine virus belonging to the family Paramyxoviridae. The only known isolate was obtained from a horse that was involved in a disease outbreak of undetermined nature and the circumstances of its isolation suggested an etiologic role. However, the experimental infection of a colostrum-deprived foal failed to reproduce the disease; only mild neutropenia and temperature elevation were recorded. An additional attempt to establish an etiological relationship with the disease was made by conducting a retrospective evaluation of the serological profiles of ...
Thinks pregnant mare urine industry inhumane.
Journal of the American Veterinary Medical Association    June 8, 2002   Volume 220, Issue 11 1612-1613 
Evans M.No abstract available
Effect of topical ophthalmic latanoprost on intraocular pressure in normal horses.
Veterinary therapeutics : research in applied veterinary medicine    June 7, 2002   Volume 3, Issue 1 72-80 
Davidson HJ, Pinard CL, Keil SM, Brightman AH, Sargeant JM.The ocular effects of latanoprost ophthalmic solution were evaluated in two studies, with eight horses in each study. One eye of each horse was treated with latanoprost ophthalmic solution once daily for 5 days, and the opposite eye received a control solution of sterile eyewash. Intraocular pressure and pupillary diameter were measured daily for 5 days after treatment. Latanoprost had no significant effect on intraocular pressure or pupillary diameter in normal horse eyes compared with control eyes in these studies. Placement of an eyelid nerve block resulted in significantly lower intraocula...
Culture, isolation and propagation of Babesia caballi from naturally infected horses.
Parasitology research    June 7, 2002   Volume 88, Issue 5 460-462 doi: 10.1007/s00436-002-0609-4
Zweygarth E, Lopez-Rebollar LM, Nurton J, Guthrie AJ.Thirteen blood samples of horses from South Africa, five of which were seropositive for Babesia caballi and eight for both B. caballi and Theileria equi, were subjected to in vitro culture to identify carrier animals. None of the animals had a detectable parasitaemia on Giemsa-stained blood smears before culture initiation. Cultures were initiated in L-cysteine-enriched medium, either in an oxygen-reduced gas mixture or in a 5% CO2-in-air atmosphere. All five animals seropositive for B. caballi were identified as carrier animals using an oxygen-reduced atmosphere, whereas only four samples bec...
Effect of sulfadiazine and pyrimethamine on selected physiologic and performance parameters in athletically conditioned thoroughbred horses during an incremental exercise stress test.
Veterinary therapeutics : research in applied veterinary medicine    June 7, 2002   Volume 3, Issue 1 49-63 
Colahan PT, Bailey JE, Johnson M, Rice BL, Chou CC, Cheeks JP, Jones GL, Yang M.Following the regimen used to treat equine protozoal myeloencephalitis, sulfadiazine (20 mg/kg) and pyrimethamine (1mg/kg) were administered orally once daily to 12 physically conditioned Thoroughbred horses for 4 consecutive days. The horses were randomly assigned to two test groups in a crossover design, with each horse serving as its own control. A stepwise exercise stress test was conducted to exhaustion. No effect on athletic performance was observed, and only marginal effects were noted in some hematologic and serochemical measurements, including decreased total white blood cell counts, ...
Effect of flunixin meglumine on selected physiologic and performance parameters of athletically conditioned thoroughbred horses subjected to an incremental exercise stress test.
Veterinary therapeutics : research in applied veterinary medicine    June 7, 2002   Volume 3, Issue 1 37-48 
Colahan PT, Bailey JE, Chou CC, Johnson M, Rice BL, Jones GL, Cheeks JP.Twelve clinically sound, healthy, athletically conditioned Thoroughbred horses were subjected to an incremental exercise stress test to determine the effects and period of detection of a single dose of flunixin meglumine (1.1 mg/kg by intravenous injection) in serum and urine by ELISA. Flunixin concentrations, performance, and hematologic and clinical chemical parameters were measured. All horses were rotated through four treatment groups of a Latin-square design providing for each horse to serve as its own control. Flunixin meglumine reduced prostaglandin F(1alpha) and thromboxane concentrati...
Use of height-specific weigh tapes to estimate the bodyweight of horses.
The Veterinary record    June 6, 2002   Volume 150, Issue 20 632-634 doi: 10.1136/vr.150.20.632
Ellis JM, Hollands T.Two thousand horses of different ages, heights and breeds were divided into two height groups of up to 14.2 hands high (hh) and more than 14.2 hh, and weighed on a weighbridge; each horse then had its weight estimated by three weigh tapes, one height specific (tape 1 or 2, depending on the animal's height) and two for general use (tapes 3 and 4). For horses up to 14.2 hh, weigh tape 1 provided the most accurate estimate of mean (sd) bodyweight (100.5 [6.2] per cent), and weigh tapes 3 and 4 were 112 (6.8) and 97-0 (6.1) per cent accurate, respectively. For horses more than 14.2 hh, weigh tape ...
[Legislation for horses–artificial insemination].
Tijdschrift voor diergeneeskunde    June 6, 2002   Volume 127, Issue 9 304-305 
Rambags B, van Markus R.No abstract available
Effect of 2-deoxy-D-glucose on gonadotropins, prolactin and serum glucose concentrations in the mare.
Animal reproduction science    June 6, 2002   Volume 71, Issue 3-4 217-228 doi: 10.1016/s0378-4320(02)00030-1
McManus CJ, Davison LA, Fitzgerald BP.In a variety of species, glucoprivation results in the suppression of the reproductive axis. Two experiments were performed to test the hypothesis that blockade of glucose metabolism via administration of the glucose inhibitor 2-deoxy-D-glucose (2DG) to mares would cause a modification in gonadotropin and prolactin secretion. Long-term ovariectomized mares (Experiment 1, n=4) or ovary-intact mares during the follicular phase of a synchronized estrous cycle (Experiment 2, n=4 per dose) were treated with 2DG. The dose of 2DG used in Experiment 1 was 100mg 2DG/kg BW, but because severe behavioral...
Inhibin concentrations in mares with granulosa cell tumors.
Theriogenology    June 4, 2002   Volume 57, Issue 7 1885-1895 doi: 10.1016/s0093-691x(02)00658-1
Bailey MT, Troedsson MH, Wheato JE.The hormone-producing equine granulosa cell tumor (GCT) may secrete high levels of inhibin. Measurement of inhibin concentrations may be useful in the diagnosis and conformation of mares with GCT. Inhibin may be measured using RIA, which recognizes dimeric alphabetaA-inhibin as well as the monomeric (free) inhibin alpha-subunit, or using a two-site immunoradiometric assay (IRMA) specific for alphabetaA-inhibin. The objective of this study was to examine concurrent relationships among alpha-inhibin (as measured using RIA), alphabetaA-inhibin (as measured using IRMA), and other hormones (testost...
A method to estimate digestible energy in horse feed.
The Journal of nutrition    June 4, 2002   Volume 132, Issue 6 Suppl 2 1771S-3S doi: 10.1093/jn/132.6.1771S
Zeyner A, Kienzle E.No abstract available
Alveolar macrophage graded hemosiderin score from bronchoalveolar lavage in horses with exercise-induced pulmonary hemorrhage and controls.
Journal of veterinary internal medicine    June 4, 2002   Volume 16, Issue 3 281-286 doi: 10.1892/0891-6640(2002)016<0281:amghsf>2.3.co;2
Doucet MY, Viel L.The objective of this study was to determine if a quantitative scoring system for evaluation of hemosiderin content of alveolar macrophages obtained by bronchoalevolar lavage provides a more sensitive test for the detection of exercise-induced pulmonary hemorrhage (EIPH) in horses than does endoscopy of the lower airways. A sample population composed of 74 Standardbred racehorses aged 2-5 years was used. Horses were grouped as either control (EIPH-negative) or EIPH-positive based on history and repeated postexertional endoscopic evaluation of the bronchial airways. Bronchoalveolar lavage was p...
Lipoic acid as an antioxidant in mature thoroughbred geldings: a preliminary study.
The Journal of nutrition    June 4, 2002   Volume 132, Issue 6 Suppl 2 1628S-31S doi: 10.1093/jn/132.6.1628S
Williams CA, Hoffman RM, Kronfeld DS, Hess TM, Saker KE, Harris PA.alpha-Lipoic acid (LA) has demonstrated antioxidant effects in humans and laboratory animals. The objective of this study was to determine whether the effects of LA are similar in horses. Five Thoroughbred geldings were supplemented with 10 mg/kg/d DL-alpha-lipoic acid in a molasses and sweet feed carrier and five received only the carrier as a placebo (CON). Blood samples were obtained at baseline (0 d), after 7 and 14 d of supplementation, and 48 h postsupplementation (16 d). Blood fractions of red and white blood cells (RBC and WBC, respectively) and plasma were analyzed for glutathione (GS...
Effect of storage time and temperature on stallion sperm DNA and fertility.
Theriogenology    June 4, 2002   Volume 57, Issue 3 1135-1142 doi: 10.1016/s0093-691x(01)00689-6
Lo CC, Thompson JA, Lowry VK, Varner DD.We used the sperm chromatin structure assay (SCSA) to study the change in stallion sperm DNA susceptibility to denaturation after exposure of extended semen to three different storage temperatures (5, 20, or 37 degrees C) at 7, 20, 31, and 46 h. In addition, we compared the rates of sperm DNA denaturation in fertile and subfertile stallions. Among fertile stallions, spermatozoa stored at 20 and 37 degrees C showed a significant (P 0.05) changes in the SCSA values measured over time, indicating maintenance of chromatin quality for up to 46 h. The COMP(alpha(t)) from stallions classified as sub...
Spinal cord injuries in horse riding.
The Medical journal of Australia    June 4, 2002   Volume 176, Issue 8 402-403 doi: 10.5694/j.1326-5377.2002.tb04470.x
Taylor TK, Roe JP.No abstract available
Generation of reactive oxygen species by equine neutrophils and their effect on motility of equine spermatozoa.
Theriogenology    June 4, 2002   Volume 57, Issue 3 1025-1033 doi: 10.1016/s0093-691x(01)00710-5
Baumber J, Vo A, Sabeur K, Ball BA.Contaminating leukocytes in the ejaculate are an important source of reactive oxygen species (ROS) in human semen. When present in sufficient numbers, they can have a detrimental influence on sperm function in humans. Unfortunately, there is little published information regarding the importance of leukocytes in stallion semen. The objectives of this study were to determine the production of hydrogen peroxide (H2O2) by activated equine neutrophils and to examine the effect of this ROS production on equine sperm motility in vitro. Motile equine spermatozoa (two ejaculates each from four stallion...
Pure preovulatory follicular fluid promotes in vitro maturation of in vivo aspirated equine oocytes.
Theriogenology    June 4, 2002   Volume 57, Issue 7 1765-1779 doi: 10.1016/s0093-691x(02)00650-7
Bøgh IB, Bézard J, Duchamp G, Baltsen M, Gérard N, Daels P, Greve T.In the mare, rates of fertilization and development are low in oocytes matured in vitro, and a closer imitation of in vivo conditions during oocyte maturation might be beneficial. The aims of the present study were, therefore, to investigate whether (1) equine oocytes can be matured in vitro in pure equine preovulatory follicular fluid, (2) priming of the follicular fluid donor with crude equine gonadotrophins (CEG) before aspiration of preovulatory follicular fluid promotes the in vitro maturation rate, (3) the in vitro maturation rate differs between oocytes aspirated during estrus and those...
Iodine balance in relation to iodine intake in ponies.
The Journal of nutrition    June 4, 2002   Volume 132, Issue 6 Suppl 2 1767S-8S doi: 10.1093/jn/132.6.1767S
Wehr U, Englschalk B, Kienzle E, Rambeck WA.No abstract available
Interactions between the apparent energy and nutrient digestibilities of a concentrate mixture and roughages in horses.
The Journal of nutrition    June 4, 2002   Volume 132, Issue 6 Suppl 2 1778S-80S doi: 10.1093/jn/132.6.1778S
Kienzle E, Fehrle S, Opitz B.No abstract available
Serum response after oral supplementation of different zinc compounds in horses.
The Journal of nutrition    June 4, 2002   Volume 132, Issue 6 Suppl 2 1769S-70S doi: 10.1093/jn/132.6.1769S
Wichert B, Kreyenberg K, Kienzle E.No abstract available
Zinc, copper and selenium intake and status of horses in Bavaria.
The Journal of nutrition    June 4, 2002   Volume 132, Issue 6 Suppl 2 1776S-7S doi: 10.1093/jn/132.6.1776S
Wichert B, Frank T, Kienzle E.No abstract available
Artifactual changes in equine blood following storage, detected using the Advia 120 hematology analyzer.
Veterinary clinical pathology    June 1, 2002   Volume 31, Issue 2 90-94 doi: 10.1111/j.1939-165x.2002.tb00286.x
Clark P, Mogg TD, Tvedten HW, Korcal D.Delayed analysis of blood samples may be caused by restricted access to laboratories. Artifactual changes may occur in the measured analytes as a consequence of delayed analysis and may complicate interpretation of the data. Objective: The purpose of this study was to characterize artifactual changes in equine blood, due to storage, using the Advia 120 hematology analyzer. Methods: Samples of blood from 5 horses were analyzed using the Advia 120 soon after collection and again after 24 and 48 hours of storage at either 4 degrees C or ambient laboratory temperature ( approximately 24 degrees C)...