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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Post-breeding endometritis in the mare.
Animal reproduction science    June 14, 2000   Volume 60-61 221-232 doi: 10.1016/s0378-4320(00)00110-x
Watson ED.Post-breeding endometritis is a major cause of subfertility in the mare. Endometritis is a normal event in the immediate period after mating, but the presence of ultransonographically visible uterine fluid more than 12 h later is thought to be evidence of uterine pathology. In mares that are free of venerally transmitted endometritis, treatment is aimed at removing the intraluminal fluid. If the endometritis persists past day 5, when the embryo enters the uterine lumen, the cytotoxic environment will not be compatible with pregnancy. Reproductive anatomy, defective myometrial contractility, lo...
Use of repetitive sequence-based polymerase chain reaction for molecular epidemiologic analysis of Streptococcus equi subspecies equi.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 699-705 doi: 10.2460/ajvr.2000.61.699
Al-Ghamdi GM, Kapur V, Ames TR, Timoney JF, Love DN, Mellencamp MA.To determine whether repetitive sequence-based polymerase chain reaction (rep-PCR) could be used to differentiate Streptococcus equi isolates, to examine S equi isolates from throughout the world, and to determine whether a horse had > 1 subtype of S equi during an outbreak of disease. Methods: An initial group of 32 S equi isolates, 63 S equi isolates from various geographic areas, and 17 S equi isolates obtained during outbreaks of disease. Methods: An aliquot of S equi genomic DNA was amplified, using enterobacterial repetitive intergenic consensus primers. Gel electrophoresis was perfor...
Effects of warm-up intensity on kinetics of oxygen consumption and carbon dioxide production during high-intensity exercise in horses.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 638-645 doi: 10.2460/ajvr.2000.61.638
Geor RJ, McCutcheon LJ, Hinchcliff KW.To compare effects of low and high intensity warm-up exercise on oxygen consumption (VO2) and carbon dioxide production (VCO2) in horses. Methods: 6 moderately conditioned adult Standard-breds. Methods: Horses ran for 2 minutes at 115% of maximum oxygen consumption (VO2max), 5 minutes after each of the following periods: no warm-up (NoWU); 10 minutes at 50% of VO2max (LoWU); or 7 minutes at 50% VO2max followed by 45-second intervals at 80, 90, and 100% VO2max (HiWU). Oxygen consumption and VCO2 were measured during exercise, and kinetics of VO2 and VCO2 were calculated. Accumulated O2 deficit ...
Gait and speed as exercise components of risk factors associated with onset of fatigue injury of the third metacarpal bone in 2-year-old Thoroughbred racehorses.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 602-608 doi: 10.2460/ajvr.2000.61.602
Boston RC, Nunamaker DM.To determine the degree to which components of the training program of 2-year-old Thoroughbred racehorses influence their susceptibility to fatigue injury of the third metacarpal bone (bucked shins). Methods: 226 two-year-old Thoroughbred racehorses. Methods: Daily training information and health reports on 2-year-old Thoroughbreds were compiled from records provided from 5 commercial stables. For each horse, data (exercise variables) were collected that comprised distance jogged (approx speed of 5 m/s), galloped (approx 11 m/s), and breezed (approx 15 to 16 m/s) until a single instance of buc...
Concentrations of substance P and prostaglandin E2 in synovial fluid of normal and abnormal joints of horses.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 714-718 doi: 10.2460/ajvr.2000.61.714
Kirker-Head CA, Chandna VK, Agarwal RK, Morris EA, Tidwell A, O'Callaghan MW, Rand W, Kumar MS.To correlate substance P content of synovial fluid with prostaglandin E2 content, radiographic evidence of joint abnormality, and anatomic location of the joint for normal and osteoarthritic joints of horses. Methods: Synovial fluid from 46 normal joints in 21 horses and 16 osteoarthritic joints in 10 horses. Methods: Normal and osteoarthritic joints were identified by clinical and radiographic examination, by response to nerve blocks, during scintigraphy or surgery, or by clinicopathologic evaluation. Substance P and prostaglandin E2 contents of synovial fluid were determined by radioimmunoas...
Effects of interleukin-1beta and tumor necrosis factor-alpha on expression of matrix-related genes by cultured equine articular chondrocytes.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 624-630 doi: 10.2460/ajvr.2000.61.624
Richardson DW, Dodge GR.To determine the effects of interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) on expression and regulation of several matrix-related genes by equine articular chondrocytes. Methods: Articular cartilage harvested from grossly normal joints of 8 foals, 6 yearling horses, and 8 adult horses. Methods: Chondrocytes maintained in suspension cultures were treated with various doses of human recombinant IL-1beta or TNF-alpha. Northern blots of total RNA from untreated and treated chondrocytes were probed with equine complementary DNA (cDNA) probes for cartilage matrix-related ge...
[The treatment of articular and bone infections in large animals with gentamicin-impregnated collagen sponges].
Schweizer Archiv fur Tierheilkunde    June 13, 2000   Volume 142, Issue 5 292-298 
Steiner A, Hirsbrunner G, Rytz U, Zulauf M, Philipp M, Martig J.No abstract available
Pharmacokinetics of enrofloxacin administered intravenously and orally to foals.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 706-709 doi: 10.2460/ajvr.2000.61.706
Bermingham EC, Papich MG, Vivrette SL.To determine the pharmacokinetics of enrofloxacin administered IV and orally to foals. Methods: 5 clinically normal foals. Methods: A 2-dose cross-over trial with IV and oral administration was performed. Enrofloxacin was administered once IV (5 mg/kg of body weight) to 1-week-old foals, followed by 1 oral administration (10 mg/kg) after a 7-day washout period. Blood samples were collected for 48 hours after the single dose IV and oral administrations and analyzed for plasma enrofloxacin and ciprofloxacin concentrations by use of high-performance liquid chromatography. Results: For IV administ...
[Lung function tests in horses with special reference to ultrasound-spirometry/capnography].
Schweizer Archiv fur Tierheilkunde    June 13, 2000   Volume 142, Issue 5 299-303 
Herholz C, Busato A, Straub R.No abstract available
Changes in kinematic variables observed during pressure-induced forelimb lameness in adult horses trotting on a treadmill.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 612-619 doi: 10.2460/ajvr.2000.61.612
Keegan KG, Wilson DA, Smith BK, Wilson DJ.To determine whether kinematic changes induced by heel pressure in horses differ from those induced by toe pressure. Methods: 10 adult Quarter Horses. Methods: A shoe that applied pressure on the cuneus ungulae (frog) or on the toe was used. Kinematic analyses were performed before and after 2 levels of frog pressure and after 1 level of toe pressure. Values for stride displacement and time and joint angles were determined from horses trotting on a treadmill. Results: The first level of frog pressure caused decreases in metacarpophalangeal (fetlock) joint extension during stance and increases ...
Radiographic diagnosis–ethmoid hematoma. Gasser AM, Love NE, Tate LP.No abstract available
Pharmacokinetics of a long-acting oxytetracycline-polyethylene glycol formulation in horses.
Journal of veterinary pharmacology and therapeutics    June 10, 2000   Volume 23, Issue 2 107-110 doi: 10.1046/j.1365-2885.2000.00249.x
Dowling PM, Russell AM.No abstract available
Pharmacokinetics of fleroxacin in horses.
Journal of veterinary pharmacology and therapeutics    June 10, 2000   Volume 23, Issue 2 103-105 doi: 10.1046/j.1365-2885.2000.00248.x
Rebuelto M, Otero P, Albarellos G, Ambros L, Kreil V, Waxman S, Montoya L, Hallu R.No abstract available
Influence of interleukin-1beta and hyaluronan on proteoglycan release from equine navicular hyaline cartilage and fibrocartilage.
Journal of veterinary pharmacology and therapeutics    June 10, 2000   Volume 23, Issue 2 67-72 doi: 10.1046/j.1365-2885.2000.00247.x
Frean SP, Gettinby G, May SA, Lees P.Proteoglycan (PG) release, in response to recombinant human interleukin-1beta (rh-IL-1beta), was measured in cartilage explants obtained from the equine distal sesamoid bone (navicular bone). Fibrocartilage from the surface of the navicular bone apposing the deep digital flexor tendon and hyaline cartilage from the surface of the navicular bone articulating with the middle phalanx were labelled with 35SO4. Hyaline cartilage from the distal metacarpus was used as a control tissue. Following radiolabel incorporation, the three cartilage types were treated with rh-IL-1beta (100 U/mL) in the prese...
Streptococcus equi with truncated M-proteins isolated from outwardly healthy horses.
Microbiology (Reading, England)    June 10, 2000   Volume 146 ( Pt 6) 1361-1369 doi: 10.1099/00221287-146-6-1361
Chanter N, Talbot NC, Newton JR, Hewson D, Verheyen K.The M-protein genes of Streptococcus equi isolated from 17 outwardly healthy horses after 4 strangles outbreaks had ended, including a quarantined animal, were compared with those of S. equi isolates from 167 active cases of strangles across 4 countries. The healthy horses included 16 persistent S. equi carriers, at least one from each of the four outbreaks. These carriers, despite being outwardly healthy, had empyema of the guttural pouch(es), an enlargement of the equine Eustachian tube. A persistent carrier from two of these outbreaks, the quarantined animal and a healthy animal with normal...
Arthroscopic removal of patellar fracture fragments in horses: five cases (1989-1998).
Journal of the American Veterinary Medical Association    June 9, 2000   Volume 216, Issue 11 1799-1801 doi: 10.2460/javma.2000.216.1799
Marble GP, Sullins KE.To evaluate the use of arthroscopy as the primary method for removal of large patellar fracture fragments. Methods: Retrospective study. Methods: 5 performance horses of various breeds with patellar fractures. Methods: Clinical signs of lameness, external evidence of injury, and radiography were used to diagnose and determine fracture orientation. Arthroscopy of the stifle joint was performed on the affected limb with the horse positioned in dorsal recumbency and under general anesthesia. Progress after surgery was determined by evaluating medical records and via telephone conversations with o...
Incidence of equine herpesvirus 1 infection in thoroughbred weanlings on two stud farms.
Australian veterinary journal    June 7, 2000   Volume 78, Issue 4 277-278 doi: 10.1111/j.1751-0813.2000.tb11757.x
Gilkerson JR, Love DN, Whalley JM.No abstract available
A fatal case of Hendra virus infection in a horse in north Queensland: clinical and epidemiological features.
Australian veterinary journal    June 7, 2000   Volume 78, Issue 4 279-280 doi: 10.1111/j.1751-0813.2000.tb11758.x
Field HE, Barratt PC, Hughes RJ, Shield J, Sullivan ND.No abstract available
Identification and molecular characterization of Hendra virus in a horse in Queensland.
Australian veterinary journal    June 7, 2000   Volume 78, Issue 4 281-282 doi: 10.1111/j.1751-0813.2000.tb11759.x
Hooper PT, Gould AR, Hyatt AD, Braun MA, Kattenbelt JA, Hengstberger SG, Westbury HA.No abstract available
Study of the hyaloid apparatus in the neonatal thoroughbred foal.
The Veterinary record    June 6, 2000   Volume 146, Issue 20 579-584 doi: 10.1136/vr.146.20.579
Munroe G.Over 80 per cent of 169 neonatal thoroughbred foals had some part of the hyaloid artery present bilaterally and its degree of completeness, colour and character was statistically symmetrical. The complete artery was present in over 60 per cent of the foals. The incidence of the hyaloid artery and its completeness, colour and character were related to the age of the foal. The hyaloid system atrophies in the early stages of the neonatal period and generally its presence did not cause any significant ocular problems. The presence and morphology of the posterior pupillary membrane was highly corre...
Mushroom toxicity in a horse with meningioangiomatosis.
Veterinary and human toxicology    June 6, 2000   Volume 42, Issue 3 166-167 
Frazier K, Liggett A, Hines M, Styer E.We describe a fatal case of mushroom intoxication in an 18-y-o horse presumably due to Amanita verna. Horses are normally regarded as too fastidious to eat the ill-flavored toadstools. In this case, the horse had a rare benign brain tumor, meningioangiomatosis, which may have altered the horse's normal eating behavior resulting in consumption of the mushrooms.
Detecting Taxus poisoning in horses using liquid chromatography/mass spectrometry.
Veterinary and human toxicology    June 6, 2000   Volume 42, Issue 3 151-154 
Kite GC, Lawrence TJ, Dauncey EA.A method is described for the analysis of taxine alkaloids by liquid chromatography/mass spectrometry. It is applicable to the detection of taxine alkaloids in the stomach contents of horses in which Taxus poisoning is suspected. Analysis of a leaf extract of Taxus baccata revealed unreported alkaloids of the same relative molecular mass as taxine B and isotaxine B.
An in vitro study to compare 5 different techniques for injection of the navicular bursa in the horse.
Equine veterinary journal    June 3, 2000   Volume 32, Issue 3 263-267 doi: 10.2746/042516400776563635
Schramme MC, Boswell JC, Hamhougias K, Toulson K, Viitanen M.Numerous different techniques for injection of the navicular bursa have been described but there is little conformity between these descriptions. A literature review was performed and techniques for injection of the navicular bursa were categorised into 5 approaches. This study was performed to evaluate the reproducibility of each technique and to assess which technique was consistently most successful. Five inexperienced operators performed each technique on 5 cadaver forelimbs. Once a needle had been placed, a radiograph was taken to confirm placement was in accordance with the description o...
Cross-sectional study of faecal shedding of Giardia duodenalis and Cryptosporidium parvum among packstock in the Sierra Nevada Range.
Equine veterinary journal    June 3, 2000   Volume 32, Issue 3 247-252 doi: 10.2746/042516400776563545
Atwill ER, McDougald NK, Perea L.Faecal specimens from 305 horses and mules used as packstock at one of 17 commercial or governmental (National Park Service, US Forest Service) operations were examined for Giardia duodenalis and Cryptosporidium parvum using immunofluorescent microscopy. Fourteen packstock (4.6%) were shedding G. duodenalis cysts, with herd-level prevalences ranging 0-22%. Number of packstock in the corral, size of corral and density of packstock in the corral were associated with the odds of shedding G. duodenalis cysts. None of the horses had detectable C. parvum oocysts. Assuming a sensitivity of at least 4...
Six intestinal microflora-associated characteristics in sport horses.
Equine veterinary journal    June 3, 2000   Volume 32, Issue 3 222-227 doi: 10.2746/042516400776563653
Collinder E, Lindholm A, Midtvedt T, Norin E.The aim of this study was to investigate 6 microflora-associated characteristics (MACs) in faecal samples from horses and to compare the results with baselines previously established in other mammals. A MAC is defined as any anatomical structure, physiological, biochemical or immunological characteristic in a host, which has been acted on by microorganisms. When the active microbes are absent, as in germ-free animals and healthy newborn organisms, the corresponding characteristic is defined as germ-free animal characteristic (GAC). The MACs studied were degradation of mucin, conversion of chol...
Repeatability of Doppler ultrasound measurements of hindlimb blood flow in halothane anaesthetised horses.
Equine veterinary journal    June 3, 2000   Volume 32, Issue 3 239-246 doi: 10.2746/042516400776563662
Raisis AL, Young LE, Meire H, Walsh K, Taylor PM, Lekeux P.The purpose of this study was to determine the repeatability of femoral blood flow recorded using Doppler ultrasound in anaesthetised horses. Doppler ultrasound of the femoral artery and vein was performed in 6 horses anaesthetised with halothane and positioned in left lateral recumbency. Velocity spectra, recorded using low pulse repetition frequency, were used to calculate time-averaged mean velocity (TAV), velocity of component a (TaVa), velocity of component b (TaVb), volumetric flow, early diastolic deceleration slope (EDDS) and pulsatility index (PI). Within-patient variability was deter...
Respiratory responses of mature horses to intravenous lobeline bolus.
Equine veterinary journal    June 3, 2000   Volume 32, Issue 3 200-207 doi: 10.2746/042516400776563644
Marlin DJ, Roberts CA, Schroter RC, Lekeux P.The respiratory stimulant lobeline has been used in equine clinical practice to increase inspiratory and expiratory airflow rates at rest in order to facilitate investigation of both lower and upper airway function. Some of the responses to lobeline in the pony have been reported, but the detailed time course, effect of dose, possible side effects and reproducibility associated with lobeline administration have not been described in the horse. Respiratory airflow rates and oesophageal pressure were measured with a Fleisch No. 5 pneumotachometer and lightweight facemask and a microtip pressure ...
Headshaking in horses: possible aetiopathogenesis suggested by the results of diagnostic tests and several treatment regimes used in 20 cases.
Equine veterinary journal    June 3, 2000   Volume 32, Issue 3 208-216 doi: 10.2746/042516400776563617
Newton SA, Knottenbelt DC, Eldridge PR.Twenty mature horses with typical headshaking of 2 week-7 year duration were studied. Clinical examinations included radiography of the head and nasopharyngeal endoscopy. All were assessed at rest and at exercise, both before and after fitting an occlusive nasal mask, application of tinted contact lenses and the perineural anaesthesia of the infraorbital and posterior ethmoidal branches of the trigeminal nerve. Infraorbital anaesthesia had no effect in 6/7 cases but 11/17 (65%) cases showed a 90-100% improvement following posterior ethmoidal nerve anaesthesia. Tinted contact lenses had no appa...
Objectivity in the assessment of equine welfare.
Equine veterinary journal    June 3, 2000   Volume 32, Issue 3 178-179 doi: 10.2746/042516400776563671
Baker DJ, Turner GA.No abstract available
Cyclical endometrial steroid hormone receptor expression and proliferation intensity in the mare.
Equine veterinary journal    June 3, 2000   Volume 32, Issue 3 228-232 doi: 10.2746/042516400776563554
Aupperle H, Ozgen SSchoon HA, Schoon D, Hoppen HO, Sieme H, Tannapfel A.The aims of this study were to investigate the steroid hormone receptor expression and the proliferation intensity during the equine endometrial cycle by immunohistological methods, established for routine examination of formalin-fixed, paraplast-embedded specimens. Endometrial biopsy specimens were obtained during one cycle from 7 mares. In comparison with the blood steroid hormone levels the quantity and distribution of oestrogen (ER) and progesterone receptors (PR) and the proliferation marker Ki-67 antigen expression were investigated. Rising 17beta-oestradiol concentrations in preoestrus ...