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Topic:Veterinary Research

Veterinary research in horses encompasses the study of diseases, health management, and medical treatments specific to equine species. This field investigates various aspects of horse health, including infectious diseases, metabolic disorders, and musculoskeletal conditions. Researchers focus on understanding the pathophysiology of equine ailments, developing diagnostic tools, and evaluating therapeutic interventions. The study of horse health also involves examining preventive measures such as vaccination protocols and nutritional management to promote overall well-being. This page collects peer-reviewed research studies and scholarly articles that explore the diverse areas of veterinary science related to horses, providing insights into disease mechanisms, treatment strategies, and advancements in equine healthcare.
Tubuloreticular inclusions in equine connective tissue neoplasms.
Journal of comparative pathology    May 1, 1989   Volume 100, Issue 4 449-452 doi: 10.1016/0021-9975(89)90011-x
Madewell BR, Munn RJ.Abnormal irregularly branched and anastomosing tubules within cisternae of endoplasmic reticulum were observed by transmission electron microscopy in tumour cells comprising connective tissue neoplasms (sarcoids) from three horses and a mule. These tubuloreticular inclusions were also observed in cultured tumour cells from one of these horses examined, but were not detected in fibroblasts (fibrocytes), epidermis, or vascular endothelial cells in skin biopsy specimens from five clinically healthy horses, nor in one additional equine connective tissue neoplasm.
Cervical spinal kinematics: a comparison between foals and adult horses.
Equine veterinary journal    May 1, 1989   Volume 21, Issue 3 193-195 doi: 10.1111/j.2042-3306.1989.tb02141.x
Clayton HM, Townsend HG.A photographic method was used to measure axial rotation, dorsoventral flexion and extension and lateral bending at each intervertebral joint complex from the occiput to the first thoracic vertebra in spinal segments from 19 foals under 12 months of age and 14 horses over three years of age. Comparisons between the two groups showed that there was a general reduction in cervical spinal mobility with age. For the three types of movement at the eight joints tested, adults' mobility exceeded that of foals in only three cases (axial rotation and lateral bending at the A-O joint, and lateral bendin...
Rectal tears in the horse: an analysis of 35 cases.
Equine veterinary journal    May 1, 1989   Volume 21, Issue 3 186-188 doi: 10.1111/j.2042-3306.1989.tb02138.x
Watkins JP, Taylor TS, Schumacher J, Taylor JR, Gillis JP.The records of 35 horses with Grade 3 or 4 rectal tears, presented to the Veterinary Medical Center at Texas A & M University over a five year period, were reviewed. Grade 3 tears were sub-classified according to whether the remaining tissue was serosa (Grade 3a) or mesorectum (Grade 3b). Five horses were destroyed on presentation and 30 were treated by primary suture closure (8 horses), faecal diversion alone (9 horses) or in combination with suture closure (11 horses) and packing of the tear with medicated gauze sponges (two horses). Faecal diversion was achieved with a temporary indwell...
Comparative pulmonary mechanics in the horse and the cow.
Research in veterinary science    May 1, 1989   Volume 46, Issue 3 322-330 
Gallivan GJ, McDonell WN, Forrest JB.Pulmonary mechanics and lung volumes were measured in horses and cows to determine if differences in breathing pattern between the two species were due to differences in the mechanical properties of the lungs. Tidal volume (VT) was larger in the horses, while the respiratory rate (fR) and minute ventilation (VE) were higher in the cows. The horses often had a double peak in airflow during inspiration and, or, expiration, while the cows had a single peak during expiration. Measured lung volumes were larger in the horses and they had a higher dynamic lung compliance (Cdyn,L), although the static...
[The possibility of using equine serum albumin in place of bovine serum albumin and ovalbumin in radioimmunological and immunoenzyme analyses and in virological practice].
Zhurnal mikrobiologii, epidemiologii i immunobiologii    May 1, 1989   Issue 5 47-50 
Kolmakova MV, Kuskova ZR, Ratner GM, Laptakova LM.Horse serum albumin has been shown to meet the requirements to protein preparations for microanalysis and thus to be suitable for use in kits of reagents for the radioimmunological determination of insulin and myoglobin, for the determination of tick-borne encephalitis virus antigen by the method of the enzyme immunoassay and for the stabilization of proteins in the hemagglutination test and the hemagglutination inhibition test.
An unusual cause of increasing airway pressure during anesthesia.
Veterinary surgery : VS    May 1, 1989   Volume 18, Issue 3 239-241 doi: 10.1111/j.1532-950x.1989.tb01078.x
Klein LV, Wilson DV.A mare with a thoracic laceration was anesthetized with halothane-O2 for surgical repair. Shortly after initiation of controlled ventilation, inspiratory plateau pressure began to increase. The increase in pressure continued despite decreasing the tidal volume. Tension pneumothorax was suspected, but because arterial PCO2 and PO2 were normal, the anesthetic apparatus was examined. Excess gas continued to exit through the bellows pop-off valve even when the fresh gas flow was turned off. It was determined that driving gas from the ventilator was entering the breathing circuit through a hole in ...
[The “weaving” of horses].
DTW. Deutsche tierarztliche Wochenschrift    May 1, 1989   Volume 96, Issue 5 248-255 
Sambraus HH, Radtke K.Studies were made on 27 horses which were known to weave. They were stallions, mares and geldings between the ages of 3 and 22 years. The horses were individually observed for several days in their habitual surroundings. A period, in which a horse makes pauses of not more than ten minutes, is considered a weaving phase. Shorter pauses subdivide the weaving phase into weaving series. The basic unit of weaving is the weaving displacement, i.e. the head movement between the turning points. The number of daily weaving displacements of the horses examined varied from less than 400 up to almost 18,0...
Identification of the gB homologues of equine herpesvirus types 1 and 4 as disulphide-linked heterodimers and their characterization using monoclonal antibodies.
The Journal of general virology    May 1, 1989   Volume 70 ( Pt 5) 1161-1172 doi: 10.1099/0022-1317-70-5-1161
Meredith DM, Stocks JM, Whittaker GR, Halliburton IW, Snowden BW, Killington RA.Equine herpesvirus types 1 and 4 (EHV-1 and EHV-4) labelled with [14C]glucosamine were purified from infected cell culture medium and profiles of their structural proteins were obtained that enabled identification of the major glycoproteins. Nine glycosylated polypeptides were identified for each virus. Preparations of the purified viruses each contained a glycoprotein which was linked by disulphide bonds, as determined by diagonal gel electrophoresis under reducing/non-reducing conditions. High Mr forms of this glycoprotein were detected for EHV-1 when the sample was not heated. The EHV-1 pro...
A preliminary investigation of the effect of selected electromagnetic field devices on healing of cannon bone osteotomies in horses.
Equine veterinary journal    May 1, 1989   Volume 21, Issue 3 201-205 doi: 10.1111/j.2042-3306.1989.tb02145.x
Sanders-Shamis M, Bramlage LR, Weisbrode SE, Gabel AA.The effect of electrical stimulation by means of selected electromagnetic field devices on healing of cannon bone osteotomies in horses was examined. The defects were created as 3 cm x 1 mm longitudinal osteotomies through the dorsal cortices of the mid-metacarpi/metatarsi of adult horses. This type of defect would asses bone healing in a situation similar to an acute, stable fracture of the cortex. Three electromagnetic devices of different design were tested in three different groups of horses. Healing was evaluated radiographically and histologically. Results showed that osteotomies treated...
Evaluations of buparvaquone as a treatment for equine babesiosis (Babesia equi).
American journal of veterinary research    May 1, 1989   Volume 50, Issue 5 782-785 
Zaugg JL, Lane VM.We evaluated the efficacy of buparvaquone in eliminating Babesia equi of European origin in carrier horses and in experimentally infected splenectomized ponies. When administered at the rate of 2.5 mg/kg of body weight, IM, 4 times at 96-hour intervals, buparvaquone was effective in eliminating B equi carrier infection in 1 horse. Such results could not be repeated at the same dosage or at 3.5 or 5 mg/kg, IM. Buparvaquone given at the rate of 4 to 6 mg/kg IV and/or IM was therapeutically effective in 4 of 5 acute B equi infections in splenectomized ponies. The treated ponies became carriers.
Observations on the occurrence of five species of Gasterophilus larvae in free-ranging horses in Umbria, central Italy.
Veterinary parasitology    May 1, 1989   Volume 31, Issue 2 173-177 doi: 10.1016/0304-4017(89)90032-0
Principato M.Comparative data collected over 4 years show the most frequent species of Gasterophilus infesting free-ranging horses in Umbria (Central Italy) to be G. intestinalis (93.8%), G. nasalis (76.5%) and G. inermis (71%). G. pecorum and G. haemorrhoidalis were less frequent and appeared in 39.3 and 10.8% of the animals, respectively. For each of the 5 species, the duration of gastric and enteric lesions, the average numbers of larvae isolated throughout the year and the probable duration of oral lesions were discussed.
[Preservation capability of horse semen by the use of two diluents and preservation temperatures].
DTW. Deutsche tierarztliche Wochenschrift    May 1, 1989   Volume 96, Issue 5 258-265 
Tekin N, Wöckener A, Klug E.The effect of a skim milk extender and a glycine-containing extender on sperm motility and acrosome morphology of stallion semen was examined. There was no difference concerning acrosome morphology. After 24 hours of preservation motility of the ejaculates diluted with glycine extender was significantly superior to those handled with skim milk extender. Storage at 5 degrees C in all cases gave better results than storage at room temperature. Skim milk extender is an appropriate diluent when the semen is used for al on the day of its collection, whereas the glycine-containing extender offers th...
EHV-1: a recurrent problem.
The Veterinary record    April 29, 1989   Volume 124, Issue 17 443-444 doi: 10.1136/vr.124.17.443
No abstract available
Experimental trichinellosis in horses: biological and parasitological evaluation.
Veterinary parasitology    April 1, 1989   Volume 31, Issue 1 19-36 doi: 10.1016/0304-4017(89)90005-8
Soule C, Dupouy-Camet J, Georges P, Ancelle T, Gillet JP, Vaissaire J, Delvigne A, Plateau E.Three groups of three horses each were, respectively, infected with 5000, 20,000 and 50,000 larvae of Trichinella spiralis. The strain used was isolated from a human biopsy during horsemeat-related outbreaks of trichinellosis in France. Transient muscular disorders were only observed in two of the horses infected with 50,000 larvae but none of the horses had fever. A significant increase in blood eosinophils was noticed in 5 horses. Serum LDH, aldolase and CPK peaked at the fifth week post-infection. Specific IgG assayed by indirect immunofluorescence and ELISA, appeared 2-5 weeks post-infecti...
A new Papulaspora species from the infected eye of a horse: Papulaspora equi sp. nov.
Mycopathologia    April 1, 1989   Volume 106, Issue 1 35-39 doi: 10.1007/BF00436924
Shadomy HJ, Dixon DM.An unusual fungus, probably traumatically introduced into the eye of a horse while grazing, was studied on various mycological media. Upon examination of colonies the organism produced bulbils and clearly exhibited the characteristics of a new species of Papulaspora, P. equi Shadomy & Dixon.
Congenital malignant melanoma in two foals.
Journal of the American Veterinary Medical Association    April 1, 1989   Volume 194, Issue 7 945-947 
Cox JH, DeBowes RM, Leipold HW.Two cases of congenital malignant melanomas in horses are described in this report. In each case, wide surgical excision of the mass was performed; no recurrence or metastasis was detected after a minimum of 15 months' follow-up. Melanomas are among the most common neoplasms of horses, but they typically develop in gray horses greater than 6 years old.
Equine giant cell tumor of soft tissues.
The Cornell veterinarian    April 1, 1989   Volume 79, Issue 2 173-177 
Hamir AN.During a routine necropsy examination of a 4-year-old standardbred mare, a well-demarcated dermal mass was seen near the right elbow. Grossly, the mass consisted of multifocal variably sized areas of dark brown, firm material that was separated by thin white septa. Histologically, within the individual compartments, there were numerous multinucleated giant cells, macrophages, and free erythrocytes. A diagnosis of giant cell tumor of soft tissues was made.
The elimination of injected superoxide dismutase from synovial fluid of the horse.
Australian veterinary journal    April 1, 1989   Volume 66, Issue 4 117-119 doi: 10.1111/j.1751-0813.1989.tb09763.x
Auer DE, Ng JC, Hrdlicka J, Seawright AA.No abstract available
Fractures of the distal phalanx in the horse.
The Veterinary clinics of North America. Equine practice    April 1, 1989   Volume 5, Issue 1 145-160 doi: 10.1016/s0749-0739(17)30608-9
Yovich JV.Fractures of the distal phalanx are an important cause of lameness referrable to the foot. Depending on the fracture configuration and articular involvement, conservative or surgical treatment may be required. Fractures of the distal phalanx have been divided into six categories based on fracture configuration. Discussion of clinical features, management, and prognosis for horses with distal phalangeal fractures is presented for each fracture type.
Pathomorphological aspects of extremely small thymuses occurring spontaneously in Thoroughbred foals.
Nihon juigaku zasshi. The Japanese journal of veterinary science    April 1, 1989   Volume 51, Issue 2 437-440 doi: 10.1292/jvms1939.51.437
Oikawa M, Yoshihara T, Kaneko M.No abstract available
Simple nonrebreathing valves for use with large mammals. Gallivan GJ, Bignell W, McDonell WN, Whiting TL.Two simple nonrebreathing valves suitable for use with large mammals are described. These valves can be constructed in a reasonably well equipped workshop using materials that are readily available. The resistive pressure of both valves is less than 0.1 kPa at flow rates up to 15 L.s-1. Their main limitation is a relatively large dead space, although the dead space of valve B (290 mL) is less than the dead space of some commercially available valves. Healthy adult horses and cows compensate for the increased dead space by an increase in tidal volume.
Pathways between lymph vessels and sinuses in lymph nodes: a study in horses.
The Anatomical record    April 1, 1989   Volume 223, Issue 4 420-424 doi: 10.1002/ar.1092230411
Heath TJ, Perkins NR.The pathways through which lymph flows from terminal afferent lymphatics to the lymph sinuses, and from the sinuses to initial efferent lymphatics, were studied in horse lymph nodes by using Microfil casts and electron microscopy. Terminal afferent lymphatics are continuous with the subcapsular sinus through oval holes, about 3 microns wide, along their length, and through larger openings near their end. Other terminal afferents penetrate into the node within trabeculae and are supported by processes across the lumen. They connect with trabecular and medullary sinuses through oval or round hol...
Regenerative anemia in horses.
Journal of the American Veterinary Medical Association    April 1, 1989   Volume 194, Issue 7 860 
Morris DD.No abstract available
Small intestinal strangulation caused by Meckel’s diverticulum in a horse.
Journal of the American Veterinary Medical Association    April 1, 1989   Volume 194, Issue 7 943-944 
Hooper RN.Necropsy of a 12-year-old Quarter Horse mare revealed a blind-end segment of intestine originating from the antimesenteric border of the ileum. The blind-end segment had looped around and strangulated the ileum and 3.5 m of the jejunum.
Clinical anatomy of the equine foot.
The Veterinary clinics of North America. Equine practice    April 1, 1989   Volume 5, Issue 1 1-27 doi: 10.1016/s0749-0739(17)30601-6
Kainer RA.A review of investigations of the functional anatomy of the equine foot is presented. Emphasis is placed on the relationships of structures involved in the major diseases of the foot.
Overriding vertebral spinous processes in the extinct horse, Equus occidentalis.
American journal of veterinary research    April 1, 1989   Volume 50, Issue 4 592-593 
Klide AM.Lumbar and thoracic vertebrae of the extinct horse, Equus occidentalis, were examined for gross and radiographic evidence of overriding spinous processes. Of 2,661 vertebrae examined, 580 had intact spinous processes. Thirty-six intact spinous processes, which appeared grossly similar to overriding spinous processes in the modern domestic horse, E caballus caballus, were radiographed. Of these 36 vertebrae, 2 had radiographic signs compatible with a radiographic diagnosis of overriding spinous processes, ie, radiographically observed lysis and/or sclerosis. Seemingly, weight bearing or other s...
Muscular dystrophy-like disease in a thoroughbred foal.
Journal of comparative pathology    April 1, 1989   Volume 100, Issue 3 287-294 doi: 10.1016/0021-9975(89)90106-0
Shirakawa T, Ide M, Taniyama H, Tobiwatari K, Senba H, Oishi H, Matsui T, Ono T.A 1-month-old male thoroughbred foal, which had difficulty in walking, was killed and examined by histological, histochemical and ultrastructural methods. The muscles of the trunk and upper hind limbs were chiefly affected, and changes in the affected muscles resembled those in muscular dystrophy in man. The type of muscular dystrophy present in this foal and the significance of this disease in thoroughbred horses are discussed. The dystrophy in this foal resembled the limb-girdle type or myotonic dystrophy of muscular dystrophy in man.
Pathophysiology of acute laminitis.
The Veterinary clinics of North America. Equine practice    April 1, 1989   Volume 5, Issue 1 67-72 doi: 10.1016/s0749-0739(17)30604-1
Moore JN, Allen D, Clark ES.This article reviews research findings relating to the pathophysiology of acute laminitis in horses. The data presently available suggest that the onset of the condition may be due to constriction of the postcapillary vessels in the digit, leading to increased capillary hydrostatic pressure and movement of fluid into the interstitial space.
Radiographic examination of the equine foot.
The Veterinary clinics of North America. Equine practice    April 1, 1989   Volume 5, Issue 1 47-66 doi: 10.1016/s0749-0739(17)30603-x
Park RD.A complete radiographic examination of the equine foot consists of properly exposed, processed, and positioned radiographs. For radiographic interpretation, in addition to knowing radiographic signs of disease, a knowledge of normal radiographic anatomy and possible insignificant anatomic variations is necessary.
Repetitive DNA probes for the detection of Babesia equi.
Molecular and biochemical parasitology    April 1, 1989   Volume 34, Issue 1 75-78 doi: 10.1016/0166-6851(89)90021-2
Posnett ES, Ambrosio RE.This report describes DNA probes for the identification of Babesia equi. A genomic library of B. equi was constructed in pUC13. Several clones were identified that hybridized strongly to B. equi DNA. Clone pBE33 hybridized specifically to B. equi DNA and did not hybridize to horse DNA nor to DNA from Babesia caballi, Babesia bovis or Babesia bigemina. Two subclones of pBE33 (pSB20 and pEH21) containing B. equi repetitive sequences, could detect 0.49 ng and 0.97 ng B. equi DNA, respectively.