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Topic:Veterinary Science

Veterinary science and horses encompass the study and application of medical, surgical, and therapeutic practices to maintain and improve the health and welfare of equines. This field addresses a wide range of topics, including disease prevention, diagnosis, and treatment, as well as nutrition, reproduction, and behavior. Research in veterinary science for horses often involves understanding the pathophysiology of equine-specific diseases, developing advanced diagnostic techniques, and improving treatment protocols. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary science related to horses, providing insights into the latest advancements and methodologies in equine healthcare.
Hypoxic training increases maximal oxygen consumption in Thoroughbred horses well-trained in normoxia.
Journal of equine science    July 6, 2017   Volume 28, Issue 2 41-45 doi: 10.1294/jes.28.41
Ohmura H, Mukai K, Takahashi Y, Takahashi T, Jones JH.Hypoxic training is effective for improving athletic performance in humans. It increases maximal oxygen consumption (V̇Omax) more than normoxic training in untrained horses. However, the effects of hypoxic training on well-trained horses are unclear. We measured the effects of hypoxic training on V̇Omax of 5 well-trained horses in which V̇Omax had not increased over 3 consecutive weeks of supramaximal treadmill training in normoxia which was performed twice a week. The horses trained with hypoxia (15% inspired O) twice a week. Cardiorespiratory valuables were analyzed with analysis of varia...
A novel test for evaluating horses’ spontaneous visual attention is predictive of attention in operant learning tasks.
Die Naturwissenschaften    July 5, 2017   Volume 104, Issue 7-8 61 doi: 10.1007/s00114-017-1480-6
Rochais C, Sébilleau M, Houdebine M, Bec P, Hausberger M, Henry S.Attention is described as the ability to process selectively one aspect of the environment over others. In this study, we characterized horses' spontaneous attention by designing a novel visual attention test (VAT) that is easy to apply in the animal's home environment. The test was repeated over three consecutive days and repeated again 6 months later in order to assess inter-individual variations and intra-individual stability. Different patterns of attention have been revealed: 'overall' attention when the horse merely gazed at the stimulus and 'fixed' attention characterized by fixity and...
West Nile virus infection in horses, Indian ocean.
Comparative immunology, microbiology and infectious diseases    July 4, 2017   Volume 53 45-49 doi: 10.1016/j.cimid.2017.06.006
Cardinale E, Bernard C, Lecollinet S, Rakotoharinome VM, Ravaomanana J, Roger M, Olive MM, Meenowa D, Jaumally MR, Melanie J, Héraud JM, Zientara S....The circulation of West Nile virus (WNV) in horses was investigated in the Southwest Indian ocean. In 2010, blood samples were collected from a total of 303 horses originating from Madagascar, Mauritius, Reunion and the Seychelles and tested for WNV-specific antibodies. An overall seroprevalence of 27.39% was detected in the Indian Ocean with the highest WNV antibody prevalence of 46.22% (95% CI: [37.4-55.2%]) in Madagascar. The age and origin of the horses were found to be associated with the WNV infection risk. This paper presents the first seroprevalence study investigating WN fever in hors...
An exploratory study of competition scores and salivary cortisol concentrations in Warmblood horses.
Domestic animal endocrinology    June 28, 2017   Volume 61 108-116 doi: 10.1016/j.domaniend.2017.06.007
Munk R, Jensen RB, Palme R, Munksgaard L, Christensen JW.The main objective of this explorative study was to describe the relationship between competition scores and salivary cortisol concentrations in young horses during dressage and showjumping competitions. The study also investigated whether the diurnal rhythm of salivary cortisol concentrations was affected by competition over consecutive days compared with the home environment. Saliva samples were collected from 126 dressage horses and showjumpers in their home environment and at 3 different events. The relationship between scores given by judges at the competition and cortisol concentrations ...
Differential distribution of vapA-positive Rhodococcus equi in affected and unaffected horse-breeding farms.
The Veterinary record    June 22, 2017   Volume 181, Issue 6 145 doi: 10.1136/vr.104088
Petry S, Sévin C, Fleury MA, Duquesne F, Foucher N, Laugier C, Henry-Amar M, Tapprest J.No abstract available
Cross-validation analysis for genetic evaluation models for ranking in endurance horses.
Animal : an international journal of animal bioscience    June 21, 2017   Volume 12, Issue 1 20-27 doi: 10.1017/S1751731117001331
García-Ballesteros S, Varona L, Valera M, Gutiérrez JP, Cervantes I.Ranking trait was used as a selection criterion for competition horses to estimate racing performance. In the literature the most common approaches to estimate breeding values are the linear or threshold statistical models. However, recent studies have shown that a Thurstonian approach was able to fix the race effect (competitive level of the horses that participate in the same race), thus suggesting a better prediction accuracy of breeding values for ranking trait. The aim of this study was to compare the predictability of linear, threshold and Thurstonian approaches for genetic evaluation of...
Playing with fire – What is influencing horse owners’ decisions to not vaccinate their horses against deadly Hendra virus infection?
PloS one    June 21, 2017   Volume 12, Issue 6 e0180062 doi: 10.1371/journal.pone.0180062
Goyen KA, Wright JD, Cunneen A, Henning J.Hendra virus is a zoonotic paramyxovirus, which causes severe respiratory and neurological disease in horses and humans. Since 2012, the Hendra virus sub-unit G vaccine has been available for horse vaccination in Australia. Uptake of the vaccine has been limited and spill-over events of Hendra virus infection in horses continue to occur. We conducted an online, questionnaire-based cross-sectional study of 376 horse owners belonging to a variety of different equestrian clubs in Queensland, Australia, to identify risk factors for non-vaccination against Hendra virus. A total of 43.1% (N = 162) o...
Feed intake patterns of sport ponies and warmblood horses following iso-energetic intake of pelleted fibre-rich mixed feed, muesli feed and semicrushed oat grains.
Journal of animal physiology and animal nutrition    June 20, 2017   Volume 101 Suppl 1 37-42 doi: 10.1111/jpn.12732
Bochnia M, Boesel M, Bahrenthien L, Wensch-Dorendorf M, Zeyner A.The aim of the study was to compare diverse feed intake patterns in sport ponies and warmblood-type horses after feeding iso-energetic amounts of three different concentrates: a pelleted fibre-rich mixed feed (PF), a muesli feed (MF) and semicrushed oat grains (OG). Four sport ponies and six warmblood-type horses received the concentrates and meadow hay according to maintenance (0.52 MJ metabolizable energy (ME) kg body weight (BW) /day). Both breeds were allocated at random to three groups and received once daily for 8 days either OG (1 g starch/kg BW/meal) or iso-energetic quantities of ...
Online turbulent flow extraction coupled with liquid chromatography-tandem mass spectrometry for high throughput screening of anabolic steroids in horse urine.
Journal of pharmaceutical and biomedical analysis    June 19, 2017   Volume 145 46-51 doi: 10.1016/j.jpba.2017.06.036
Shin HD, Suh JH, Kim J, Cho HD, Lee SD, Han KS, Wang Y, Han SB.A high throughput method for simultaneous screening of anabolic steroids and their metabolites (4-esterendione, trenbolone, boldenone, oxandrolone, nandrolone, methandrostenolone, testosterone, 1-androstendione, ethisterone, normethandrolone, methyltestosterone, 16β-Hydroxystanozolol, epitestosterone, bolasterone, norethandrolone, danazol, stanozolol and androstadienone) in equine urine by online turbulent flow extraction coupled with liquid chromatography-tandem mass spectrometry was developed. The use of turbulent flow chromatography could simplify pretreatment of horse urine, which has com...
Science-in-brief: Workshop report The Dorothy Havemeyer International Equine Endocrinology Summit.
Equine veterinary journal    June 13, 2017   Volume 49, Issue 4 408-409 doi: 10.1111/evj.12686
Durham AE, Bailey SR, Frank N, McFarlane D, Schott HC, Paradis MR.No abstract available
Artificially extended photoperiod administered to pre-partum mares via blue light to a single eye: Observations on gestation length, foal birth weight and foal hair coat at birth.
Theriogenology    June 9, 2017   Volume 100 126-133 doi: 10.1016/j.theriogenology.2017.06.012
Nolan MB, Walsh CM, Duff N, McCrarren C, Prendergast RL, Murphy BA.In seasonally breeding animals, photoperiod perception is crucial for timing of important physiological events. In the horse, long day photoperiod influences the onset of ovulation and cyclicity, shedding of the heavier winter coat and the timing of parturition. In this compilation of studies, conducted across three breeding seasons and two countries, the impact of artificially extended day length was investigated on gestation length, foal birth weight and foal hair coat at birth. The light therapy was administered to pre-partum mares via mobile head worn masks which provided short wavelength ...
A new equine and zoonotic threat emerges from an old avian pathogen, Chlamydia psittaci. Polkinghorne A, Greub G.No abstract available
Molecular detecting of piroplasms in feeding and questing Ixodes ricinus ticks.
Annals of parasitology    June 2, 2017   Volume 63, Issue 1 21-26 doi: 10.17420/ap6301.80
Adamska M, Skotarczak B.The purpose of this study was to detect piroplasms, which are pathogens of veterinary and zoonotic importance in ticks, that were collected from ponies and field vegetation and to determine the role of Shetland ponies as potential reservoir hosts for piroplasms. A total of 1737 feeding and 371 questing Ixodes ricinus collected from horses or vegetation were tested for the presence of Babesia and Theileria DNA. Piroplasm 18S rRNA gene amplification was conducted, and the obtained amplicons were sequenced. Babesia DNA was detected in only three ticks (one tick collected from a pony and two colle...
Results of the Schirmer tear test performed with open and closed eyes in clinically normal horses.
Acta veterinaria Scandinavica    May 31, 2017   Volume 59, Issue 1 35 doi: 10.1186/s13028-017-0303-2
Trbolova A, Ghaffari MS.The Schirmer tear test (STT) is widely used in both human and veterinary ophthalmology. Two types of STTs have been developed: STT I and SST II. The STT I measures the basal and reflex tear production and is the most widely used STT. However, several factors influence the STT results such as the person performing the test and the location of the strip placement within the conjunctival sac. The aim of this study was to measure the basal and reflex tear production (STT I) in clinically normal horses with open versus closed eyes. Results: Forty clinically healthy horses without any ocular disease...
Assessment of agreement among diplomates of the American College of Veterinary Anesthesia and Analgesia for scoring the recovery of horses from anesthesia by use of subjective grading scales and development of a system for evaluation of the recovery of horses from anesthesia by use of accelerometry.
American journal of veterinary research    May 26, 2017   Volume 78, Issue 6 668-676 doi: 10.2460/ajvr.78.6.668
Clark-Price SC, Lascola KM, Carter JE, da Cunha AF, Donaldson LL, Doherty TJ, Martin-Flores M, Hofmeister EH, Keating SCJ, Mama KR, Mason DE....OBJECTIVE To evaluate agreement among diplomates of the American College of Veterinary Anesthesia and Analgesia for scores determined by use of a simple descriptive scale (SDS) or a composite grading scale (CGS) for quality of recovery of horses from anesthesia and to investigate use of 3-axis accelerometry (3AA) for objective evaluation of recovery. ANIMALS 12 healthy adult horses. PROCEDURES Horses were fitted with a 3AA device and then were anesthetized. Eight diplomates evaluated recovery by use of an SDS, and 7 other diplomates evaluated recovery by use of a CGS. Agreement was tested with...
A proteomic study of mesenchymal stem cells from equine umbilical cord.
Theriogenology    May 24, 2017   Volume 100 8-15 doi: 10.1016/j.theriogenology.2017.05.015
Maia L, de Moraes CN, Dias MC, Martinez JB, Caballol AO, Testoni G, de Queiroz CM, Peña RD, Landim-Alvarenga FC, de Oliveira E.To the best of our knowledge, this is the first study describing the proteome of equine umbilical cord intervascular matrix mesenchymal stem cells (UCIM-MSCs) in a global and functional manner. The aim of this work was to analyze the proteome of previously characterized UCIM-MSCs to determine protein abundance and classify the identified proteins according to Gene Ontology (GO) terms. Protein classification analysis according to biological process, molecular function and cellular component was performed using the PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification Syst...
Use of contrast media in computed tomography and magnetic resonance imaging in horses: Techniques, adverse events and opportunities.
Equine veterinary journal    May 22, 2017   Volume 49, Issue 4 410-424 doi: 10.1111/evj.12689
Nelson BB, Goodrich LR, Barrett MF, Grinstaff MW, Kawcak CE.The use of contrast media in computed tomography (CT) and magnetic resonance imaging (MRI) is increasing in horses. These contrast-enhanced imaging techniques provide improved tissue delineation and evaluation, thereby expanding diagnostic capabilities. While generally considered safe, not all contrast media exhibit the same safety profiles. The safety of contrast media use and descriptions of adverse events occurring in horses are sparsely reported. This review summarises the reported evidence of contrast media use and adverse events that occur in horses, with added contribution from other ve...
Different training schedules influence platelet aggregation in show jumping horses.
Polish journal of veterinary sciences    May 20, 2017   Volume 20, Issue 1 149-154 doi: 10.1515/pjvs-2017-0019
Giannetto C, Arfuso F, Fazio F, Giudice E, Pietro SD, Bruschetta D, Piccione G.Depending on the intensity, duration and type of physical exercise, equine metabolism has to adapt to nervous, cardiovascular, endocrine and respiratory system requirements. In horses, exercise and training are known to have considerable effects on the mechanisms of hemostatic system involving platelet activity. The aim of the present study was to evaluate the effect of different training schedules on platelet aggregation in 15 Italian Saddle jumping horses. Animals were divided into three equal groups: Group A was subjected to a high intensity-training program; group B to a light training pro...
Recent clinical trials of cancer immunogene therapy in companion animals.
World journal of experimental medicine    May 20, 2017   Volume 7, Issue 2 42-48 doi: 10.5493/wjem.v7.i2.42
This mini-review presents the results of veterinary clinical trials on immunogene therapy published from 2014 to 2016. A variety of tumors, among them melanoma (canine and equine), mastocytoma (canine), mammary adenocarcinoma (canine) and fibrosarcoma (feline) were treated by using diverse strategies. Non-viral vectors were usually employed to transfer genes of cytokines, suicide enzymes and/or tumor associated antigens. In general terms, minor or no adverse collateral effects were related to these procedures, and treated patients frequently improved their conditions (better quality of life, d...
What is your diagnosis? Blood smear from a horse.
Veterinary clinical pathology    May 19, 2017   Volume 46, Issue 3 542-543 doi: 10.1111/vcp.12504
Boes KM, Weinstein NM.No abstract available
Ingestive mastication in horses resembles rumination but not ingestive mastication in cattle and camels.
Journal of experimental zoology. Part A, Ecological and integrative physiology    May 17, 2017   Volume 327, Issue 2-3 98-109 doi: 10.1002/jez.2075
Dittmann MT, Kreuzer M, Runge U, Clauss M.Horses achieve a higher degree of particle size reduction through ingestive mastication than functional ruminants. We characterized mastication using chew-monitoring halters (RumiWatch) in six domestic horses, cattle, and Bactrian camels each. All animals were offered grass hay of the same batch for 15 min. In cattle and camels, measurements were continued after eating until rumination was observed. Except for one horse, 96% of the horses' ingestive mastication data were identified as "rumination" by the proprietary RumiWatch algorithm, whereas ingestion and rumination by cattle and camels wer...
Preliminary investigations into a novel, long-acting, injectable, intramuscular formulation of omeprazole in the horse.
Equine veterinary journal    May 17, 2017   Volume 49, Issue 6 795-801 doi: 10.1111/evj.12688
Sykes BW, Kathawala K, Song Y, Garg S, Page SW, Underwood C, Mills PC.Pilot investigations have suggested that a novel, long-acting, injectable i.m. formulation of omeprazole (LA-OMEP) can induce acid suppression for up to 7 days following a single injection. Objective: To investigate the pharmacodynamics and assess the clinical efficacy of the LA-OMEP formulation. Methods: Part A comprised a pharmacodynamic study. Part B consisted of a pilot clinical trial. Methods: Part A enrolled six adult Thoroughbred horses with percutaneous gastrotomy tubes. Intragastric pH was measured for continuous 23-h periods (08.00-07.00 h) for eight consecutive days (days 0-7). A si...
Are horses capable of mirror self-recognition? A pilot study.
PloS one    May 16, 2017   Volume 12, Issue 5 e0176717 doi: 10.1371/journal.pone.0176717
Baragli P, Demuru E, Scopa C, Palagi E.Mirror Self-Recognition (MSR) unveils complex cognitive, social and emotional skills and it has been found only in humans and few other species, such as great apes, dolphins, elephants and magpies. In this pilot study, we tested if horses show the capacity of MSR. Four subjects living socially under naturalistic conditions were selected for the experiment. We adopted the classical mark test, which consists in placing a coloured mark on an out-of-view body part, visible only through mirror inspection. If the animal considers the image as its own, it will use its reflection to detect the mark an...
High metabolic activity of tissue-nonspecific alkaline phosphatase not only in young but also in adult bone as demonstrated using a new histochemical detection protocol.
General and comparative endocrinology    May 11, 2017   Volume 258 109-118 doi: 10.1016/j.ygcen.2017.05.008
Maly IP, Eppler E, Müller-Gerbl M.Tissue-nonspecific alkaline phosphatase (TNAP) is playing a key role in bone calcification, as has been demonstrated in different mammalian species including human and rodents. However, to investigate age-related changes during life history, histochemical demonstration of TNAP is severely hampered, particularly in the elderly, by technical difficulties associated with sectioning calcified tissue. Sufficient fixation must precede decalcification since poorly fixed bone tissue is exposed to the deleterious effects of decalcification reagents. In order to find a method that would allow cryosectio...
Lack of significant associations with early career performance suggest no link between the DMRT3 “Gait Keeper” mutation and precocity in Coldblooded trotters.
PloS one    May 10, 2017   Volume 12, Issue 5 e0177351 doi: 10.1371/journal.pone.0177351
Jäderkvist Fegraeus K, Lawrence C, Petäjistö K, Johansson MK, Wiklund M, Olsson C, Andersson L, Andersson LS, Røed KH, Ihler CF, Strand E....The Swedish-Norwegian Coldblooded trotter (CBT) is a local breed in Sweden and Norway mainly used for harness racing. Previous studies have shown that a mutation from cytosine (C) to adenine (A) in the doublesex and mab-3 related transcription factor 3 (DMRT3) gene has a major impact on harness racing performance of different breeds. An association of the DMRT3 mutation with early career performance has also been suggested. The aim of the current study was to investigate this proposed association in a randomly selected group of CBTs. 769 CBTs (485 raced, 284 unraced) were genotyped for the DMR...
Galloping Hooves in Africa: Horse, Zebra, or Wildebeest?
Annals of the American Thoracic Society    May 2, 2017   Volume 14, Issue 5 624-625 doi: 10.1513/AnnalsATS.201701-061ED
Rylance S, Mortimer K.No abstract available
Discrimination of Streptococcus equi subsp. equi and Streptococcus equi subsp. zooepidemicus using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Mani RJ, Thachil AJ, Ramachandran A.Accurate and timely identification of infectious etiologies is of great significance in veterinary microbiology, especially for critical diseases such as strangles, a highly contagious disease of horses caused by Streptococcus equi subsp. equi. We evaluated a matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) platform for use in species- and subspecies-level identification of S. equi isolates from horses and compared it with an automated biochemical system. We used 25 clinical isolates each of S. equi subsp. equi and S. equi subsp. zooepidemicus. Using ...
Phenotypic and Genetic Analysis of the Leopard Complex Spotting in Noriker Horses.
The Journal of heredity    April 30, 2017   Volume 108, Issue 5 505-514 doi: 10.1093/jhered/esx039
Druml T, Grilz-Seger G, Neuditschko M, Neuhauser B, Brem G.Genetic analyses of coat colors are frequently restricted to subjectively categorized phenotype information. The aim of this study was to develop a method to numerically quantify the variability of leopard complex (LP) spotting phenotypes introducing tools from image analysis. Generalized Procrustes analysis eliminates systematic errors due to imaging process. The binarization of normalized images and the application of principal component analysis (PCA) on the derived pixel matrices, transform pixel information into numerical data space. We applied these methods on 90 images to ascertain the ...
Laparoscopic evaluation of the small intestine in the standing horse: Technique and effects.
Veterinary surgery : VS    April 29, 2017   Volume 46, Issue 6 812-820 doi: 10.1111/vsu.12664
Jones ARE, Ragle CA, Anderson D, Scott C.To evaluate the feasibility and clinical outcomes after laparoscopic evaluation of the small intestines via laparoscopy. Methods: Prospective pilot study. Methods: Healthy adult horses (n = 5). Methods: Horses were restrained in standing stocks and received an infusion of detomidine. One port was placed in the left last intercostal space and 3 ports were placed in the right paralumbar fossa. The small intestine was run with atraumatic laparoscopic grasping forceps, from the duodenocolic plica to the ileocecal plica. Postoperative pain was scored every 4 hours for the first 48 hours. Horses...
Molecular confirmation of Sarcocystis fayeri in a donkey.
Veterinary parasitology    April 29, 2017   Volume 240 30-33 doi: 10.1016/j.vetpar.2017.04.026
Coultous RM, Raftery AG, Shiels BR, Sutton DGM, Weir W.Sarcocystis fayeri is a canine protozoan parasite with an equine intermediate host. Historically classified as an incidental pathogen, recent literature has described the toxic effects of Sarcocystis fayeri in human food poisoning, and highlighted potential involvement in equine neuromuscular disease. Until now, horses were believed to be the exclusive intermediate host. This study reports the first molecular confirmation of S. fayeri in a donkey, and gives rise to the consideration of donkeys being a potential reservoir for the parasite. This finding is of particular importance in understandi...
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