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Home / Equine Research Bank / Antibiotics (Basel) / Antimicrobial Resistance in Equines: A Growing Threat to Hor...
Antibiotics (Basel, Switzerland)2024; 13(8); doi: 10.3390/antibiotics13080713

Antimicrobial Resistance in Equines: A Growing Threat to Horse Health and Beyond-A Comprehensive Review.

Abstract: The equine industry holds substantial economic importance not only in the USA but worldwide. The occurrence of various infectious bacterial diseases in horses can lead to severe health issues, economic losses, and restrictions on horse movement and trade. Effective management and control of these diseases are therefore crucial for the growth and sustainability of the equine industry. While antibiotics constitute the primary treatment strategy for any bacterial infections in horses, developing resistance to clinically important antibiotics poses significant challenges to equine health and welfare. The adverse effects of antimicrobial overuse and the escalating threat of resistance underscore the critical importance of antimicrobial stewardship within the equine industry. There is limited information on the epidemiology of antimicrobial-resistant bacterial infections in horses. In this comprehensive review, we focus on the history and types of antimicrobials used in horses and provide recommendations for combating drug-resistant bacterial infections in horses. This review also highlights the epidemiology of antimicrobial resistance (AMR) in horses, emphasizing the public health significance and transmission dynamics between horses and other animals within a One Health framework. By fostering responsible practices and innovative control measures, we can better help the equine industry combat the pressing threat of AMR and thus safeguard equine as well as public health.
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Publication Date: 2024-07-29 PubMed ID: 39200013PubMed Central: PMC11350719DOI: 10.3390/antibiotics13080713Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article reviews the growing threat of antimicrobial resistance (AMR) in horses, its implications for the equine industry and beyond, and offers innovations for mitigating this problem.

Antimicrobial Resistance Significance

  • The threat of antimicrobial resistance (AMR) in horses is escalating, with the equine industry contributing significantly to global economies. This directly impacts the holistic health of horses and economic viability.
  • Bacterial infectious diseases in horses can lead to critical health conditions, economic losses and even disrupt horse movement and trade. As such, the effective management of these diseases is essential for the sustainability of the equine industry.
  • Antibiotics are primarily used for treating bacterial infections in horses, but there’s a growing resistance to these antibiotics which poses significant health and welfare challenges for the horses.

The Adverse Impact of Antimicrobial Overuse

  • The progression and threat of resistance are further aggravated due to the overuse of antimicrobials, emphasizing the need for antimicrobial stewardship within the equine industry.
  • There’s a lack of sufficient information on the epidemiology (spread and control) of antimicrobial-resistant bacterial infections in horses highlighting the need for more comprehensive research in this area.

Study Focus and Recommendations

  • The review provides a detailed examination of the history and types of antimicrobials used in horses, with suggestions for fighting drug-resistant bacterial infections.
  • The researchers highlight the epidemiology of AMR in horses, underlining its public health importance in the context of the One Health approach- considering human health, animal health, and environmental health as interconnected.
  • The researchers emphasize the necessity of promoting responsible practices and innovative control measures to counter the looming threat of AMR and hence protect both equine and public health.

Cite This Article

APA
Kabir A, Lamichhane B, Habib T, Adams A, El-Sheikh Ali H, Slovis NM, Troedsson MHT, Helmy YA. (2024). Antimicrobial Resistance in Equines: A Growing Threat to Horse Health and Beyond-A Comprehensive Review. Antibiotics (Basel), 13(8). https://doi.org/10.3390/antibiotics13080713

Publication

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
NlmUniqueID: 101637404
Country: Switzerland
Language: English
Volume: 13
Issue: 8

Researcher Affiliations

Kabir, Ajran
  • Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, Martin-Gatton College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546, USA.
Lamichhane, Bibek
  • Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, Martin-Gatton College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546, USA.
Habib, Tasmia
  • Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, Martin-Gatton College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546, USA.
Adams, Alexis
  • Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, Martin-Gatton College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546, USA.
  • College of Veterinary Medicine, Lincoln Memorial University, Harrogate, TN 37752, USA.
El-Sheikh Ali, Hossam
  • Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, Martin-Gatton College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546, USA.
Slovis, Nathan M
  • McGee Medical Center, Hagyard Equine Medical Institute, 4250 Iron Works Pike, Lexington, KY 40511, USA.
Troedsson, Mats H T
  • Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, Martin-Gatton College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546, USA.
Helmy, Yosra A
  • Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, Martin-Gatton College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546, USA.

Grant Funding

  • KL2 TR001996 / NCATS NIH HHS
  • P20 GM130456 / NIGMS NIH HHS

Conflict of Interest Statement

The authors declare no conflicts of interest.

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