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Animals : an open access journal from MDPI2025; 15(6); 864; doi: 10.3390/ani15060864

Exploring the Use of Helminthophagous Fungi in the Control of Helminthoses in Horses: A Review.

Abstract: Equine farming faces growing challenges with helminthoses, aggravated by the indiscriminate use of anthelmintics without technical criteria. This practice favors resistance to these drugs, generates residues in animal products, compromises food safety and human health, and, when excreted in large quantities, negatively impacts environmental health by affecting invertebrates and fecal microorganisms. This highlights the importance of the One Health approach. A promising alternative is biological control with nematophagous or helminthophagous fungi such as , , , , and . Due to their different mechanisms of action, ovicidal and predatory fungi, when used together, can act in a complementary and synergistic way in the biological control of helminths, increasing their effectiveness in reducing parasitic infections. The use of these fungi through biosynthesized nanoparticles from fungal filtrates is also emerging as a new approach to nematode control. It can be administered through feed supplementation in commercial formulations. The aim of this review is to explore the use of helminthophagous fungi in the control of helminthiases in horses, highlighting their potential as a biological alternative. It also aims to understand how these fungi can contribute effectively and sustainably to parasite management in horses.
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Publication Date: 2025-03-18 PubMed ID: 40150393PubMed Central: PMC11939784DOI: 10.3390/ani15060864Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article explores the use of certain types of fungi, like nematophagous or helminthophagous fungi, as a potential biological method to manage parasitic helminths in horses. The article suggests that incorporating these particular fungi into horse feed could reduce harmful effects caused by other commonly used de-worming drugs.

Purpose and Context

  • The research presents a review on tackling the challenges of helminthoses, a common parasitic infection in horses generally managed through anthelmintics. However, the unregulated usage of these drugs has led to complications such as drug resistance, antibiotics residue, and health risks for both consumers and the environment.
  • The focus of the study lies in keeping in line with the ‘One Health’ approach, inferring that the health of humans, animals, and environment are all interconnected. Therefore, suggesting better alternatives to control these helminth infections becomes essential.

Alternative to Existing Treatments

  • The research proposes biological control using nematophagous or helminthophagous fungi for controlling helminthoses, reducing reliance on standard de-worming methods.
  • These fungi types either showcase predatory behavior or ovicidal actions, killing or incapacitating the parasites. When both varieties are used in tandem, they can deliver a potent, effective means to combat and reduce parasitic infections.

Fungus Application

  • The study suggests that these fungi could be implemented through a novel approach. The fungi can be processed into biosynthesized nanoparticles derived from their filtrates, enabling easier administration.
  • This fungi-infused nanoparticle treatment can be included in commercial feed formulations for ease of use and yielding a wider reach.

Objective and Scope

  • This review aims to highlight the potential of helminthophagous fungi in controlling helminthiases in domesticated horses. It seeks to present this fungi-based approach as an effective and sustainable alternative to anthelmintics.
  • The objective is to understand the potential implications of these fungi in parasitic management and to reinforce the importance of exploring sustainable and safe parasite control strategies in equine farming.

Cite This Article

APA
do Carmo TA, Fonseca JDS, Braga FR, Paz-Silva A, de Soutello RVG, de Araújo JV. (2025). Exploring the Use of Helminthophagous Fungi in the Control of Helminthoses in Horses: A Review. Animals (Basel), 15(6), 864. https://doi.org/10.3390/ani15060864

Publication

Animals : an open access journal from MDPI
ISSN: 2076-2615
NlmUniqueID: 101635614
Country: Switzerland
Language: English
Volume: 15
Issue: 6
PII: 864

Researcher Affiliations

do Carmo, Tábata Alves
  • Department of Veterinary Medicine, Federal University of Viçosa-UFV, Viçosa 36570-900, MG, Brazil.
Fonseca, Júlia Dos Santos
  • Department of Epidemiology and Public Health, Federal Rural University of Rio de Janeiro-UFRRJ, Seropédica 23890-000, RJ, Brazil.
Braga, Fabio Ribeiro
  • Laboratory of Experimental Parasitology and Biological Control, Vila Velha University-UVV, Vila Velha 29102-920, ES, Brazil.
Paz-Silva, Adolfo
  • Department of Animal Pathology, University of Santiago de Compostela-USC, 27002 Lugo, Galícia, Spain.
de Soutello, Ricardo Velludo Gomes
  • School of Agrarian and Technological Sciences, Universidade Estadual Paulista-UNESP, Dracena 17900-000, SP, Brazil.
de Araújo, Jackson Victor
  • Department of Veterinary Medicine, Federal University of Viçosa-UFV, Viçosa 36570-900, MG, Brazil.

Grant Funding

  • Finance Code 001 / Coordenau00e7u00e3o de Aperfeicoamento de Pessoal de Nu00edvel Superior

Conflict of Interest Statement

The authors declare no conflict of interest.

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Citations

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