Neuropathic pain management in chronic laminitis.
Abstract: Managing pain in horses afflicted by chronic laminitis is one of the greatest challenges in equine clinical practice because it is the dreadful suffering of the animals that most often forces the veterinarian to end the battle with this disease. The purpose of this review is to summarize our current understanding of the complex mechanisms involved in generating and amplifying pain in animals with laminitis and, based on this information, to propose a modified approach to pain therapy. Furthermore, a recently developed pain scoring technique is presented that may help better quantify pain and the monitoring of responses to analgesic treatment in horses with laminitis.
Copyright (c) 2010 Elsevier Inc. All rights reserved.
Publication Date: 2010-06-11 PubMed ID: 20699178DOI: 10.1016/j.cveq.2010.04.002Google Scholar: Lookup
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Summary
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The research article discusses the complexity of managing neuropathic pain in horses suffering from chronic laminitis, a disease affecting their hooves. The article presents our current understanding of how pain is generated and increased in these cases, and proposes a modified approach to alleviating pain. It also introduces a new scoring technique for measuring pain and monitoring the effectiveness of treatments.
Understanding Pain in Chronic Laminitis in Horses
- One of the primary challenges identified in the research is managing the pain experienced by horses affected by chronic laminitis. This pain, being severe and persistent, often leads veterinarians to make the tough call of euthanizing the horse to relieve its suffering.
- The study summaries the intricate mechanisms that lead to the generation and amplification of pain in horses with this condition. This understanding could help develop more effective treatment strategies to alleviate the condition.
Proposed Modified Approach to Pain Therapy
- Based on the intricate understanding of pain mechanisms, the research proposes a modified approach to treating pain in laminitis-affected horses.
- While the exact nature of this approach isn’t discussed in the abstract, it implies that it diverges from conventional methods and could be more effective at addressing neuropathic pain in such cases.
New Pain Scoring Technique
- The research introduces a recently developed pain scoring technique that aims to help veterinarians quantify the level of pain in horses afflict by laminitis and monitor their response to analgesic treatment.
- This new technique could allow clinicians to measure the severity of the condition in a standardized way, monitor changes over time, and evaluate the effectiveness of different treatments or therapeutic strategies.
- This method may also provide a more objective and accurate measure than traditional methods, potentially leading to more personalized and effective treatments.
Cite This Article
APA
Driessen B, Bauquier SH, Zarucco L.
(2010).
Neuropathic pain management in chronic laminitis.
Vet Clin North Am Equine Pract, 26(2), 315-337.
https://doi.org/10.1016/j.cveq.2010.04.002 Publication
Researcher Affiliations
- Section of Emergency/Critical Care and Anesthesia, Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, 382 West Street Road, Kennett Square, Philadelphia, PA 19348, USA. Driessen@vet.upenn.edu
MeSH Terms
- Animals
- Foot Diseases / diagnosis
- Foot Diseases / therapy
- Foot Diseases / veterinary
- Hoof and Claw
- Horse Diseases / diagnosis
- Horse Diseases / therapy
- Horses
- Inflammation / diagnosis
- Inflammation / therapy
- Inflammation / veterinary
- Neuralgia / diagnosis
- Neuralgia / therapy
- Neuralgia / veterinary
- Pain / diagnosis
- Pain / veterinary
- Pain Management
Citations
This article has been cited 9 times.- Douglas H, Midon M, Shroff K, Floriano D, Driessen B, Hopster K. Caudal epidural catheterization for pain management in 48 hospitalized horses: A descriptive study of demographics, complications, and outcomes. Front Vet Sci 2022;9:995299.
- Story MR, Nout-Lomas YS, Aboellail TA, Selberg KT, Barrett MF, Mcllwraith CW, Haussler KK. Dangerous Behavior and Intractable Axial Skeletal Pain in Performance Horses: A Possible Role for Ganglioneuritis (14 Cases; 2014-2019). Front Vet Sci 2021;8:734218.
- Daradics Z, Crecan CM, Rus MA, Morar IA, Mircean MV, Cătoi AF, Cecan AD, Cătoi C. Obesity-Related Metabolic Dysfunction in Dairy Cows and Horses: Comparison to Human Metabolic Syndrome. Life (Basel) 2021 Dec 16;11(12).
- Shihadih DS, Harris TR, Kodani SD, Hwang SH, Lee KSS, Mavangira V, Hamamoto B, Guedes A, Hammock BD, Morisseau C. Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine. Front Vet Sci 2020;7:580.
- Pollard D, Wylie CE, Verheyen KLP, Newton JR. Identification of modifiable factors associated with owner-reported equine laminitis in Britain using a web-based cohort study approach. BMC Vet Res 2019 Feb 12;15(1):59.
- Guedes A, Galuppo L, Hood D, Hwang SH, Morisseau C, Hammock BD. Soluble epoxide hydrolase activity and pharmacologic inhibition in horses with chronic severe laminitis. Equine Vet J 2017 May;49(3):345-351.
- Lancaster LS, Bowker RM. Acupuncture Points of the Horse's Distal Thoracic Limb: A Neuroanatomic Approach to the Transposition of Traditional Points. Animals (Basel) 2012 Sep 17;2(3):455-71.
- Guedes AG, Morisseau C, Sole A, Soares JH, Ulu A, Dong H, Hammock BD. Use of a soluble epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis. Vet Anaesth Analg 2013 Jul;40(4):440-8.
- Muthuraman A, Singh N. Attenuating effect of Acorus calamus extract in chronic constriction injury induced neuropathic pain in rats: an evidence of anti-oxidative, anti-inflammatory, neuroprotective and calcium inhibitory effects. BMC Complement Altern Med 2011 Mar 22;11:24.
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