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The Veterinary clinics of North America. Equine practice2018; 34(1); 141-153; doi: 10.1016/j.cveq.2017.11.009

New Perspectives in Equine Intestinal Parasitic Disease: Insights in Monitoring Helminth Infections.

Abstract: Regular anthelmintic treatment has contributed to anthelmintic resistance in horse helminths. This mass anthelmintic treatment was originally developed owing to a lack of larvicidal drugs against Strongylus vulgaris. The high prevalence of anthelmintic resistance and shortening of strongyle egg reappearance period after avermectins/moxidectins requires epidemiologically appropriate and sustainable measures. Selective anthelmintic treatment is a much-needed deworming approach: More than 50% of adult horses manifest no strongyle egg excretion. In this article, selective anthelmintic treatment procedure is described, with the specific focus on the advantages of an evidence-based, medically appropriate, and sustainable treatment system that slows the development of anthelmintic resistance.
Publication Date: 2018-02-06 PubMed ID: 29426708DOI: 10.1016/j.cveq.2017.11.009Google Scholar: Lookup
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Summary

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This research article examines the impact of excessive anthelmintic treatment (de-worming medicines) on horses, highlighting the increasing resistance of equine intestinal parasites to such treatment. The paper proposes a more selective and sustainable treatment strategy to slow down this resistance.

Current Anthelmintic Treatment Practices

  • The paper reveals that regular anthelmintic (de-worming) treatments in horses have led to the development of resistance in horse helminths, or worms.
  • This mass treatment strategy was originally developed due to an absence of larvicidal drugs, specifically geared to eliminate Strongylus vulgaris, a common type of worm that affects horses.

Problems with Current Treatments

  • The research points out that due to this routine and widespread usage of anthelmintics, there has been an alarming spike in anthelmintic resistance among equine intestinal parasites.
  • The egg reappearance period, or the time it takes for worm eggs to reappear in a horse’s system post-treatment, is also shortening, particularly for treatments using avermectins/moxidectins.

Proposed Selective Treatment Strategy

  • The paper suggests that a selective anthelmintic treatment should be adopted as an alternative to mass treatment.
  • Supporting this claim, the research specifies that more than half of adult horses show no sign of strongyle egg excretion. This emphasizes that it may not be necessary to treat all horses with anthelmintics regularly.
  • The selective treatment procedure entails only treating horses that show evidence of helminth infection, thus reducing the unnecessary exposure of parasites to anthelmintic drugs.

Advantages of Selective Treatment

  • The article highlights the benefits of an evidence-based, medically appropriate, and sustainable treatment system that slows the development of anthelmintic resistance.
  • These advantages include the reduction of unnecessary medical treatments, the sustainability of treatment practices, and a trend towards slower development of resistance by parasites.

Cite This Article

APA
Pfister K, van Doorn D. (2018). New Perspectives in Equine Intestinal Parasitic Disease: Insights in Monitoring Helminth Infections. Vet Clin North Am Equine Pract, 34(1), 141-153. https://doi.org/10.1016/j.cveq.2017.11.009

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 34
Issue: 1
Pages: 141-153

Researcher Affiliations

Pfister, Kurt
  • Parasite Consulting GmbH, Wendschatzstrasse 8, CH-3006 Berne, Switzerland; Institute of Comp. Tropical Medicine and Parasitology, LMU - University Munich, Munich, Germany. Electronic address: kpfister@duc.ch.
van Doorn, Deborah
  • Department of Infectious Diseases and Immunology, Faculty of Vet. Medicine, Utrecht University, Yalelaan 1, 3584CL Utrecht, The Netherlands.

MeSH Terms

  • Animals
  • Anthelmintics / administration & dosage
  • Drug Resistance
  • Helminthiasis, Animal / diagnosis
  • Helminthiasis, Animal / drug therapy
  • Helminthiasis, Animal / parasitology
  • Horse Diseases / diagnosis
  • Horse Diseases / drug therapy
  • Horse Diseases / parasitology
  • Horses

Citations

This article has been cited 8 times.
  1. Nielsen MK, Pyatt A, Perrett J, Tydén E, van Doorn D, Pihl TH, Schmidt JS, von Samson-Himmelstjerna G, Beasley A, Abbas G, Jabbar A. Global equine parasite control guidelines: Consensus or confusion?. Int J Parasitol Drugs Drug Resist 2025 Aug;28:100600.
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  2. Kuzmina TA, Königová A, Antipov A, Kuzmin Y, Kharchenko V, Syrota Y. Changes in equine strongylid communities after two decades of annual anthelmintic treatments at the farm level. Parasitol Res 2024 Nov 25;123(11):394.
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    doi: 10.1128/spectrum.02356-22pubmed: 35946940google scholar: lookup
  5. Jürgenschellert L, Krücken J, Bousquet E, Bartz J, Heyer N, Nielsen MK, von Samson-Himmelstjerna G. Occurrence of Strongylid Nematode Parasites on Horse Farms in Berlin and Brandenburg, Germany, With High Seroprevalence of Strongylus vulgaris Infection. Front Vet Sci 2022;9:892920.
    doi: 10.3389/fvets.2022.892920pubmed: 35754549google scholar: lookup
  6. Roelfstra L, Quartier M, Pfister K. Preliminary Data from Six Years of Selective Anthelmintic Treatment on Five Horse Farms in France and Switzerland. Animals (Basel) 2020 Dec 15;10(12).
    doi: 10.3390/ani10122395pubmed: 33333748google scholar: lookup
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    doi: 10.1186/s13071-019-3445-4pubmed: 31036059google scholar: lookup