Status of equine viral arteritis in Kentucky, 1985.

Abstract: Clinical cases of equine arteritis virus infection have not been diagnosed in Kentucky since 1984, and there has been no indication that any of the horses involved in the 1984 epizootic have since been responsible for spread of the disease to horses in other states or other countries. Cases of abortion caused by naturally acquired infection with this virus have not been confirmed in 1984 or 1985. Neither field nor vaccine strains of equine arteritis virus have been shown to induce teratologic abnormalities or the carrier state in foals born to infected or vaccinated mares. The carrier stallion appears to have played a major epidemiologic role in the dissemination and perpetuation of the virus. A commercial modified live equine viral arteritis vaccine was found to be safe and efficacious for stallions and mares. The disease can be controlled by immunizing the stallion population and by restricting the breeding of equine arteritis virus-shedding stallions to vaccinated or seropositive mares, followed by an appropriate period of isolation from other nonvaccinated Equidae.
Publication Date: 1987-07-01 PubMed ID: 3038806
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Summary

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This article examines the status of equine viral arteritis in Kentucky as of 1985, noting no new cases since 1984, and asserts that a commercial vaccine is both safe and effective in controlling the spread of the virus among horses.

Overview of the Research Article

  • The article discusses the current situation of equine arteritis virus in Kentucky as of 1985. It explains that there have been no clinical detections of equine arteritis virus since 1984 both within Kentucky and infections spreading to other states or countries.
  • The authors also mention that there haven’t been any verified instances of abortion caused by a naturally acquired virus in horses during the years 1984 and 1985, suggesting that the spread of the disease has been effectively controlled.

Findings on Equine Arteritis Virus

  • The paper finds that neither field nor vaccine strains of equine arteritis virus have led to teratologic abnormalities or the carrier state in foals born to either infected or vaccinated mares. This is significant because it indicates that the transmission of the virus can be effectively controlled through vaccination without any adverse effects on the offspring.
  • Interestingly, the research suggests that stallions seem to play an important role in the perpetuation and spread of the virus, implying that measures to control the disease must also focus on this group.

Efficacy of a Commercial Vaccine

  • The researchers found that a commercial modified live equine viral arteritis vaccine was safe and effective in stallions and mares. This finding is important for proposing measures to control the spread of this disease.
  • The paper suggests that the control of equine arteritis virus can be achieved by first immunizing the stallion population and then restricting the breeding of equine arteritis virus-shedding stallions to only vaccinated or seropositive mares.
  • Additionally, it recommends an appropriate period of isolation from nonvaccinated equines for the mares, which shows that both vaccinations and isolation measures are required to control the spread of this virus in horse populations.

Cite This Article

APA
Timoney PJ, McCollum WH, Roberts AW, McDonald MJ. (1987). Status of equine viral arteritis in Kentucky, 1985. J Am Vet Med Assoc, 191(1), 36-39.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 191
Issue: 1
Pages: 36-39

Researcher Affiliations

Timoney, P J
    McCollum, W H
      Roberts, A W
        McDonald, M J

          MeSH Terms

          • Animals
          • Antibodies, Viral / analysis
          • Arteritis / epidemiology
          • Arteritis / transmission
          • Arteritis / veterinary
          • Carrier State / transmission
          • Carrier State / veterinary
          • Equartevirus / immunology
          • Horse Diseases / epidemiology
          • Horse Diseases / transmission
          • Horses
          • Kentucky
          • Vaccination / veterinary
          • Viral Vaccines
          • Virus Diseases / epidemiology
          • Virus Diseases / transmission
          • Virus Diseases / veterinary

          Citations

          This article has been cited 5 times.
          1. Carossino M, Loynachan AT, Canisso IF, Cook RF, Campos JR, Nam B, Go YY, Squires EL, Troedsson MHT, Swerczek T, Del Piero F, Bailey E, Timoney PJ, Balasuriya UBR. Equine Arteritis Virus Has Specific Tropism for Stromal Cells and CD8(+) T and CD21(+) B Lymphocytes but Not for Glandular Epithelium at the Primary Site of Persistent Infection in the Stallion Reproductive Tract.. J Virol 2017 Jul 1;91(13).
            doi: 10.1128/JVI.00418-17pubmed: 28424285google scholar: lookup
          2. Zhang J, Go YY, Huang CM, Meade BJ, Lu Z, Snijder EJ, Timoney PJ, Balasuriya UB. Development and characterization of an infectious cDNA clone of the modified live virus vaccine strain of equine arteritis virus.. Clin Vaccine Immunol 2012 Aug;19(8):1312-21.
            doi: 10.1128/CVI.00302-12pubmed: 22739697google scholar: lookup
          3. Timoney PJ, McCollum WH. Equine viral arteritis.. Can Vet J 1987 Nov;28(11):693-5.
            pubmed: 17422919
          4. Glaser AL, Chirnside ED, Horzinek MC, de Vries AA. Equine arteritis virus.. Theriogenology 1997 Apr 15;47(6):1275-95.
            doi: 10.1016/s0093-691x(97)00107-6pubmed: 16728076google scholar: lookup
          5. Chirnside ED. Equine arteritis virus: an overview.. Br Vet J 1992 May-Jun;148(3):181-97.
            doi: 10.1016/0007-1935(92)90044-2pubmed: 1319787google scholar: lookup