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Home / Equine Research Bank / Biomolecules / The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medi...
Biomolecules2021; 11(8); doi: 10.3390/biom11081141

The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medicine and Their Use in Musculoskeletal Disorders.

Abstract: Regenerative medicine is a dynamically developing field of human and veterinary medicine. The animal model was most commonly used for mesenchymal stem cells (MSCs) treatment in experimental and preclinical studies with a satisfactory therapeutic effect. Year by year, the need for alternative treatments in veterinary medicine is increasing, and other applications for promising MSCs and their biological derivatives are constantly being sought. There is also an increase in demand for other methods of treating disease states, of which the classical treatment methods did not bring the desired results. Cell therapy can be a realistic option for treating human and animal diseases in the near future and therefore additional research is needed to optimize cell origins, numbers, or application methods in order to standardize the treatment process and assess its effects. The aim of the following work was to summarize available knowledge about stem cells in veterinary medicine and their possible application in the treatment of chosen musculoskeletal disorders in dogs and horses.
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Publication Date: 2021-08-02 PubMed ID: 34439807PubMed Central: PMC8391453DOI: 10.3390/biom11081141Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article focuses on the growing role of mesenchymal stem cells (MSCs) in veterinary medicine, particularly in treating musculoskeletal disorders in animals such as dogs and horses. It discusses the increase in demand for alternative treatments where conventional ones fail and advocates for further research in stem cell therapy.

Understanding Regenerative Medicine and MSCs

  • The paper introduces regenerative medicine as a developing field in both human and veterinary medicine.
  • Mesenchymal stem cells (MSCs), used in regenerative medicine, are a major focus of the study. These cells have been widely used in preclinical and experimental studies using animal models.
  • The authors state that the studies have shown a satisfactory therapeutic effect, indicating that MSCs can be a viable alternative to traditional treatments.

Demand for Alternative Treatments

  • According to the authors, the demand for alternative treatments in veterinary medicine is on the rise.
  • This demand is driven by the lack of desired results from conventional treatment methods for various diseases.
  • The authors propose that cell therapy, such as the use of MSCs, could serve as a potential alternative treatment strategy.

Future of Cell Therapy

  • While advocating for the use of cell therapy, the authors also recognize the need for additional research in this field.
  • They stress the importance of optimizing crucial factors such as cell origins, numbers, and application methods to create a standardized treatment process.
  • By doing so, it will be easier to assess the effects of these treatments, further advancing the science of stem cell therapy.

Stem Cell Use in Veterinary Medicine

  • The paper summarises what is currently known about the use of stem cells in veterinary medicine, particularly with regard to treating musculoskeletal disorders in animals like dogs and horses.
  • This review of scientific literature contributes to a wider understanding of stem cell application in the veterinary medicine field.

Cite This Article

APA
Prządka P, Buczak K, Frejlich E, Gąsior L, Suliga K, Kiełbowicz Z. (2021). The Role of Mesenchymal Stem Cells (MSCs) in Veterinary Medicine and Their Use in Musculoskeletal Disorders. Biomolecules, 11(8). https://doi.org/10.3390/biom11081141

Publication

Biomolecules
ISSN: 2218-273X
NlmUniqueID: 101596414
Country: Switzerland
Language: English
Volume: 11
Issue: 8

Researcher Affiliations

Prządka, Przemysław
  • Department of Surgery, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Science, Pl. Grunwadzki 51, 50-366 Wroclaw, Poland.
Buczak, Krzysztof
  • Department of Surgery, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Science, Pl. Grunwadzki 51, 50-366 Wroclaw, Poland.
Frejlich, Ewelina
  • 2nd Department of General Surgery and Surgical Oncology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland.
Gąsior, Ludwika
  • Vets & Pets Veterinary Clinic, Zakladowa 11N, 50-231 Wroclaw, Poland.
Suliga, Kamil
  • Student Veterinary Surgical Society "LANCET", Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Science, Pl. Grunwaldzki 51, 50-366 Wroclaw, Poland.
Kiełbowicz, Zdzisław
  • Department of Surgery, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Science, Pl. Grunwadzki 51, 50-366 Wroclaw, Poland.

MeSH Terms

  • Adipose Tissue / cytology
  • Adipose Tissue / immunology
  • Animals
  • Bone Marrow Cells / cytology
  • Bone Marrow Cells / immunology
  • Cell- and Tissue-Based Therapy / methods
  • Cell- and Tissue-Based Therapy / veterinary
  • Dogs
  • Female
  • Horses
  • Humans
  • Mesenchymal Stem Cell Transplantation / methods
  • Mesenchymal Stem Cell Transplantation / veterinary
  • Mesenchymal Stem Cells / cytology
  • Mesenchymal Stem Cells / immunology
  • Musculoskeletal Diseases / immunology
  • Musculoskeletal Diseases / pathology
  • Musculoskeletal Diseases / therapy
  • Musculoskeletal Diseases / veterinary
  • Placenta / cytology
  • Placenta / immunology
  • Pregnancy
  • Regenerative Medicine / methods
  • Transplantation, Autologous
  • Transplantation, Homologous
  • Umbilical Cord / cytology
  • Umbilical Cord / immunology
  • Veterinary Medicine / methods

Conflict of Interest Statement

The authors declare no conflict of interest.

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