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The Veterinary clinics of North America. Equine practice2026; 42(1); 87-97; doi: 10.1016/j.cveq.2025.12.008

Updates on Diagnosis and Treatment of Guttural Pouch Conditions.

Abstract: The complex anatomy and unique features of the equine guttural pouch create diagnostic and treatment challenges. Novel surgical approaches, as well as transendoscopic devices and medications, have improved the management of guttural pouch conditions, such as mycosis, empyema, tympany, and temporohyoid osteoarthropathy. Guidelines for Streptococcus equi subspecies equi diagnosis and disinfection protocols are strengthened by new evidence for point-of-care polymerase chain reaction, serial sampling for determining carrier status, and evaluation of disinfection techniques.
Publication Date: 2026-02-20 PubMed ID: 41723006DOI: 10.1016/j.cveq.2025.12.008Google Scholar: Lookup
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Summary

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Updates in diagnosing and treating diseases of the equine guttural pouch have led to improved management strategies through new surgical techniques, advanced endoscopic tools, and better diagnostic and disinfection protocols.

Introduction to Guttural Pouch Conditions

  • The guttural pouch is a unique anatomical structure in horses, which poses specific challenges for diagnosis and treatment.
  • Common diseases of the guttural pouch include mycosis (fungal infection), empyema (pus accumulation), tympany (air accumulation causing swelling), and temporohyoid osteoarthropathy (bone and joint disease).

Advances in Surgical and Medical Treatment

  • Novel surgical techniques have been developed to better access and treat guttural pouch conditions, reducing complications and improving outcomes.
  • Transendoscopic devices, which allow direct visualization and minimally invasive intervention inside the pouch, have expanded treatment options.
  • New medications delivered via endoscopy contribute to more effective therapy for infections and inflammation inside the pouch.

Improved Diagnostic Protocols

  • New evidence supports the use of point-of-care polymerase chain reaction (PCR) testing to rapidly detect Streptococcus equi subspecies equi, the bacteria causing strangles, a contagious equine respiratory disease involving the guttural pouch.
  • Serial sampling from the guttural pouch is recommended to accurately determine carrier status, which informs treatment decisions and helps prevent disease spread.

Enhanced Disinfection Guidelines

  • Disinfection protocols have been refined using recent research on effective techniques to eliminate infectious agents in the guttural pouch environment.
  • These guidelines help reduce risks of reinfection or transmission during and after treatment.

Summary

  • The complex nature of the equine guttural pouch requires a multifaceted diagnostic and therapeutic approach.
  • Technological advances in endoscopy and PCR testing, combined with updated surgical methods and disinfection protocols, have significantly improved management outcomes for various guttural pouch diseases.

Cite This Article

APA
Mudge M, Hostnik LD. (2026). Updates on Diagnosis and Treatment of Guttural Pouch Conditions. Vet Clin North Am Equine Pract, 42(1), 87-97. https://doi.org/10.1016/j.cveq.2025.12.008

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 42
Issue: 1
Pages: 87-97
PII: S0749-0739(25)00076-8

Researcher Affiliations

Mudge, Margaret
  • Department of Veterinary Clinical Sciences, American College of Veterinary Surgeons (Large Animal), American College of Veterinary Emergency and Critical Care (Large Animal), The Ohio State University, Columbus, OH, USA. Electronic address: mudge.3@osu.edu.
Hostnik, Laura D
  • Department of Veterinary Clinical Sciences, American College of Veterinary Internal Medicine (Large Animal), The Ohio State University, 601 Vernon Tharp Street, Columbus, OH 43210, USA.

MeSH Terms

  • Animals
  • Horses
  • Horse Diseases / diagnosis
  • Horse Diseases / therapy
  • Horse Diseases / microbiology
  • Ear Diseases / veterinary
  • Ear Diseases / diagnosis
  • Ear Diseases / therapy

Conflict of Interest Statement

Disclosures The authors have nothing to disclose.

Citations

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