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Equine veterinary journal.
Publisher:
Equine Veterinary Journal, Ltd. Hobokken, NJ : Wiley (2009)
Frequency: 8 issues per year, 2009-
Country: United States
Language: English
Author(s):
British Equine Veterinary Association.
Start Year:1968 -
ISSN:
0425-1644 (Print)
2042-3306 (Electronic)
0425-1644 (Linking)
2042-3306 (Electronic)
0425-1644 (Linking)
Impact Factor
2.2
2022
| NLM ID: | 173320 |
| (DNLM): | E11740000(s) |
| (OCoLC): | 01568146 |
| Coden: | EQVJAI |
| LCCN: | sn 83005310 |
| Classification: | W1 EQ967 |
Thoracic aortic rupture in horses. The aorta can rupture at the aortic root or aortic arch. In most breeds, the aortic root is the likely site and rupture leads to aortocardiac fistula with communication between the aorta and the right atrium, right ventricle and/or the interventricular septum. There is a high prevalence of aortic rupture in young Friesian horses and rupture occurs at the aortic arch with pseudoaneurysm and potentially aortopulmonary fistulation. Echocardiographic and post-mortem techniques must be adapted to identify aortic arch rupture that is not generally identified with standard approaches. Given the narro...
Subclinical ultrasonographic abnormalities of the suspensory ligament branches in National Hunt racehorses. Suspensory ligament branch (SLB) desmopathy is a common cause of lameness and an important cause of lost training in the Thoroughbred racing industry. Studies have assessed the impact of insertional injuries of the SLB on the careers of flat racehorses and established the prevalence of subclinical ultrasonographic SLB abnormalities in this population, but little work has investigated SLB injury in National Hunt (NH) racehorses. Objective: To investigate the prevalence of subclinical ultrasonographic SLB abnormalities in NH racehorses with no clinical signs or history of SLB injury and to estab...
Semi-automated International Cartilage Repair Society scoring of equine articular cartilage lesions in optical coherence tomography images. Arthroscopic optical coherence tomography (OCT) is a promising tool for the detailed evaluation of articular cartilage injuries. However, OCT-based articular cartilage scoring still relies on the operator's visual estimation. Objective: To test the hypothesis that semi-automated International Cartilage Repair Society (ICRS) scoring of chondral lesions seen in OCT images could enhance intra- and interobserver agreement of scoring and its accuracy. Methods: Validation study using equine cadaver tissue. Methods: Osteochondral samples (n = 99) were prepared from 18 equine metacarpophalangeal joint...
Factors associated with survival of horses following relaparotomy. Relaparotomy may be required to investigate and manage complications that occur following surgical management of colic. Objective: To report factors associated with survival following relaparotomy. Methods: Retrospective cohort study. Methods: Records of horses that had undergone exploratory laparotomy for treatment of colic over a 10-year period (2002-2012) and had undergone relaparotomy <8 weeks following the initial surgery were reviewed. Descriptive data were generated and association with survival time was modelled using Cox proportional hazards models. Results: Relaparotomy was perfor...
The preventive effects of two nutraceuticals on experimentally induced acute synovitis. Nutraceuticals are often used in the management of equine osteoarthritis, but scientific evidence of their efficacy is lacking. Objective: To study the preventive effects of two new nutraceuticals after the experimental induction of synovitis in comparison with positive and negative control treatments. Methods: Blinded, controlled, randomised experiment. Methods: Twenty-four healthy Standardbred horses were randomly allocated to supplement AT (multi-ingredient, 28 days), supplement HP (collagen hydrolysate, 60 days), meloxicam (4 days) or placebo (60 days). Synovitis was induced in the right i...
Improved radiological diagnosis of palmar osteochondral disease in the Thoroughbred racehorse. Palmar osteochondral disease (POD) is common in the Thoroughbred racehorse yet difficult to diagnose by radiography alone. Objective: To improve the sensitivity and specificity for diagnosing POD from radiographs. Methods: Prospective, longitudinal study. Methods: Radiographs in nine different projections were made of metacarpophalangeal joints (MCPJ) of 50 Thoroughbreds. Post-mortem, MCPJs were dissected and gross pathology was scored. Three experienced Thoroughbred clinicians read each radiograph and recorded their findings. Another clinician reviewed each radiograph alongside the related gr...
Risk factors in equine transport-related health problems: A survey of the Australian equine industry. Transportation can affect equine health and is a potential source of economic loss to the industry. Objective: To identify journey (duration, vehicle, commercial or noncommercial) and horse (sex, age, breed, use, amateur or professional status) characteristics associated with the development of transport-related health problems in horses. Methods: Cross-sectional online survey. Methods: An online survey was conducted targeting amateur and professional participants in the Australian equine industry; eligible respondents were required to organise horse movements at least monthly. Respondents pro...
Owner reported diseases of working equids in central Ethiopia. Working horses, donkeys and mules suffer from numerous diseases and clinical problems. However, there is little information on what owners perceive as important health concerns in their working animals. Objective: To identify and prioritise with owners the diseases and other health concerns in working equids in central Ethiopia using participatory methodologies. Methods: Participatory situation analysis (PSA). Methods: The study was conducted with carthorse- and donkey-owners in 16 sites in central Ethiopia. Multiple participatory methodologies were utilised, including ranking, matrices and fo...
Use of large-scale veterinary data for the investigation of antimicrobial prescribing practices in equine medicine. As antimicrobial resistant bacterial strains continue to emerge and spread in human and animal populations, understanding prescription practices is key in benchmarking current performance and setting goals. Antimicrobial prescription (AP) in companion veterinary species is widespread, but is neither monitored nor restricted in the USA and Canada. The veterinary use of certain antimicrobial classes is discouraged in some countries, in the hope of preserving efficacy for serious human infections. Objective: The aim of this study was to ascertain the rate of prescription of a number of 'reserved'...
Heritability and factors associated with number of harness race starts in the Spanish Trotter horse population. Longevity/durability is a relevant trait in racehorses. Genetic analysis and knowledge of factors that influence number of harness race starts would be advantageous for both horse welfare and the equine industry. Objective: To perform a genetic analysis on harness racing using number of races as a measure of longevity/durability and to identify factors associated with career length in Spanish Trotter Horses (STH). Methods: Longitudinal study. Methods: Performance data (n = 331,970) on the STH population for harness racing at national level between 1990 and 2014 were used. A grouped data model ...
The effects of dose and diet on the pharmacodynamics of omeprazole in the horse. Conflicting data are presented in the current literature regarding the efficacy of omeprazole for suppressing gastric acidity in the horse. Objective: The objective of this study was to investigate the duration of intraday acid suppression achieved with two doses of omeprazole under two different dietary conditions. Methods: A four-way crossover design. Methods: Six adult Thoroughbred horses instrumented with percutaneous gastrotomy tubes were used. Intragastric pH was measured for continuous 23 h periods (08.00-07.00 h) for six consecutive days (Days 0-5). Baseline data was recorded on Day 0 ...
Neurodegeneration in equine grass sickness is not attributable to niacin deficiency. The aetiology of equine grass sickness (EGS) is currently unknown. We hypothesised that an acute deficiency of niacin (vitamin B3), which plays a key role in neural homeostasis, may contribute to neurodegeneration in EGS. Niacin deficiency can potentially result from ingestion of niacin antagonists produced by pasture mycotoxigenic fungi. Objective: To compare the niacin status of EGS and control grazing horses. A secondary objective was to compare blood concentrations of vitamins B1, B2 and B6 in EGS and control grazing horses to determine if the status of these vitamins was altered in EGS. M...
Use of the oral sugar test in ponies when performed with or without prior fasting. It is recommended that the oral sugar test (OST) for insulin dysregulation (ID) be performed after an overnight fast, but fasting is impractical in ponies kept solely at pasture. There are few data on OST repeatability and reliability in ponies. Objective: To report 1) whether OST results obtained in the morning after an overnight fast or without fasting in the afternoon (FASTING/FED) can be used interchangeably, 2) time of highest insulin concentration T [insulin], repeatability and reliability of insulin response to the OST when FASTING or FED and 3) dichotomous agreement (ID/normal) within ...
Heritability and prevalence of selected osteochondrosis lesions in yearling Thoroughbred horses. Osteochondrosis is considered multifactorial in origin, with factors such as nutrition, conformation, body size, trauma and genetics thought to contribute to its pathogenesis. Few studies have investigated the effects of genetic variability of osteochondrosis in Thoroughbreds. Objective: To describe the prevalence and genetic variability of a subset of osteochondrosis lesions in a group of Thoroughbred yearlings. Methods: Retrospective cohort study. Methods: Radiographs of 1962 Thoroughbred yearlings were retrieved from clinical records obtained between 2005 and 2013. Pedigree information was ...
Radiographic localisation of the entheses of the equine stifle. Injury to the tendons and ligaments of the equine stifle is a common cause of lameness in horses. Individual radiographic localisation of each tendon and ligament of the stifle has not been previously reported or demonstrated in multiple radiographic projections. Objective: To create a series of radiographs identifying the origins and/or insertions of the tendons and ligaments of the equine stifle. Methods: Descriptive study of radiographic anatomy. Methods: The location of all entheses were determined by gross dissection. The proximal tibia and fibula, distal femur, patella and menisci were i...
Prospective cohort study evaluating risk factors for the development of pasture-associated laminitis in the United Kingdom. Certain individuals appear to be predisposed to recurrent pasture-associated laminitis. Previous studies have predominantly investigated risk factors only after disease occurrence. Objective: To investigate risk factors for pasture-associated laminitis prior to disease occurrence. Methods: Prospective cohort study. Methods: Non-laminitic ponies aged ≥7 years were recruited. Body condition score (BCS), height, weight, crest height and thickness were measured and an overnight dexamethasone suppression test performed. Plasma or serum adiponectin, leptin, triglyceride, basal insulin, insulin pos...
Plasma, subcutaneous tissue and bone concentrations of ceftiofur sodium after regional limb perfusion in horses. Regional limb perfusion (RLP) is an effective treatment option for injuries and infections of the distal limb in horses. Using ceftiofur sodium in RLP has been studied due to its superior spectrum of Gram-positive organisms compared to aminoglycosides, but it is not known if this antimicrobial drug adequately penetrates subcutaneous tissue and bone. Objective: To determine the concentration of ceftiofur in plasma, subcutaneous tissue and bone in horses after RLP. Methods: Experimental prospective study. Methods: Six healthy horses were used in this study. Under standing sedation, an Esmarch to...
The effect of dobutamine and bolus crystalloid fluids on the cardiovascular function of isoflurane-anaesthetised horses. Cardiac output does not always increase with dobutamine administration in anaesthetised horses and information on peripheral perfusion is lacking. Objective: To determine the effect of intravenous (i.v.) dobutamine infusion with and without a concurrent 20 mL/kg bodyweight (bwt) bolus of crystalloid fluids on the cardiovascular function of acepromazine premedicated, hypotensive, isoflurane-anaesthetised horses. Methods: Randomised, cross-over experiment. Methods: A total of 6 horses aged 5-13 years, weighing 464-578 kg were premedicated with acepromazine 0.02 mg/kg bwt and then sedated with xy...
An epidemiological survey on the prevalence of equine peripheral dental caries in the United Kingdom and possible risk factors for its development. Equine peripheral caries (PC) is an increasingly recognised disorder that causes premature wear of teeth and dental fractures and thus has major welfare implications. Little information is available on its prevalence or severity in UK horses and there are no proven associations with any risk factors. Objective: To document the prevalence of PC over a wide area of the UK, assess its intraoral distribution and severity in affected horses and examine for potential risk factors for its development. Methods: Cross sectional study. Methods: Experienced personnel were recruited for a UK wide dental s...
Soluble epoxide hydrolase activity and pharmacologic inhibition in horses with chronic severe laminitis. The roles of soluble epoxide hydrolase and lipid mediators in inflammatory and neuropathic pain could be relevant in laminitis pain management. Objective: To determine soluble epoxide hydrolase (sEH) activity in the digital laminae, sEH inhibitor potency in vitro, and efficacy of a sEH inhibitor as an adjunct analgesic therapy in chronic laminitic horses. Methods: In vitro experiments and clinical case series. Methods: sEH activity was measured in digital laminae from euthanised healthy and laminitic horses (n = 5-6/group). Potency of 7 synthetic sEH inhibitors was determined in vitro using eq...
Oesophageal lumen pH in yearling horses and effects of management and administration of omeprazole. In human subjects, arytenoid chondritis can be caused by chemical trauma of mucosa attributable to gastro-oesophageal reflux. Although a similar process may be involved in the aetiopathogenesis of arytenoid chondritis in horses, the oesophageal lumen pH in this species is poorly understood. Objective: To determine if gastro-oesophageal reflux occurs in horses by characterising oesophageal lumen pH. Methods: Blinded, randomised, placebo-controlled, crossover, experimental study. Methods: Luminal oesophageal pH in six yearling horses was recorded over four 24 h periods using an ambulatory pH rec...
Measurement of distal limb sub-bandage pressure over 96 hours in horses. Currently, there is no objective information quantifying pressures exerted by distal limb bandages. Objective: To quantify the pressure exerted by each compression layer, a polo wrap (DLP), a compression bandage (DLC), and to measure the effect of time on sub-bandage pressure. Methods: Longitudinal observational experiment. Methods: A DLC construct included a cotton roll compressed with brown gauze and elastic layers and the DLP construct included a pillow pad compressed by a cloth wrap. Dorsal and lateral sensors were placed on the mid-metacarpus. In healthy horses, sub-bandage pressures were...
A comparison of the effects of a 4% modified fluid gelatin and a 6% hydroxyethyl starch on haemodilution, colloid osmotic pressure, haemostasis and renal parameters in healthy ponies. Adverse effects on renal health and haemostasis have been documented in human patients administered hydroxyethyl starches (HESs). Gelatins may represent useful substitutes should similar adverse effects be identified in horses. Objective: To compare the effects of a 4% modified fluid gelatin (MFG) with a 6% (130/0.4) HES on haemodilution, colloid osmotic pressure (COP), haemostasis and renal parameters in healthy ponies. Methods: Randomised crossover experiment. Methods: Three treatments (Treatment A: 10 ml/kg bwt HES; Treatment B: 10 ml/kg bwt MFG; Treatment C: 20 ml/kg bwt MFG) were administ...
Evidence for marsh mallow (Malva parviflora) toxicosis causing myocardial disease and myopathy in four horses. Investigation of toxicosis caused by Malva parviflora was required after 4 horses from the same farm developed severe muscle fasciculations, tachycardia, sweating and periods of recumbency leading to death or euthanasia after ingesting the plant. Objective: To describe historical, clinical, clinicopathological and pathological findings of 4 horses with suspected M. parviflora toxicosis. The role of cyclopropene fatty acids (found in M. parviflora) and mechanism for toxicosis are proposed. Methods: Case series. Methods: Historical, physical examination, clinicopathological and pathological find...
Objective assessment of gait in xylazine-induced ataxic horses. There is poor agreement between observers of equine neurological gait abnormalities using the modified Mayhew grading scale. Objective: To stimulate a dose-dependent ataxia in horses through xylazine administration and identify quantifiable relevant gait parameters. Methods: Balanced, randomised, 2-way crossover design. Methods: Eight horses were assessed before and after administration of xylazine (low dose and high dose). Gait analyses performed before and after xylazine administration included: 1) kinematic data collected on an equine high-speed treadmill (flat and 10% decline) and from acc...
