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Topic:Anatomy

Anatomy in horses encompasses the study of the structural organization of the equine body, including the bones, muscles, organs, and systems that function together to sustain life and enable movement. Understanding equine anatomy is important for veterinarians, equine scientists, and horse owners, as it provides insights into how horses move, how they respond to external stimuli, and how various conditions can affect their health and performance. Key anatomical features in horses include the musculoskeletal system, which provides support and locomotion; the cardiovascular system, which circulates blood and nutrients; and the respiratory system, which facilitates gas exchange. This page compiles peer-reviewed research studies and scholarly articles that explore the detailed anatomy of horses, focusing on the structure and function of different body systems, their interrelationships, and their relevance to equine health, performance, and veterinary care.
Radiological anatomy of the donkey’s foot: objective characterisation of the normal and laminitic donkey foot.
Equine veterinary journal    June 3, 2011   Volume 43, Issue 4 478-486 doi: 10.1111/j.2042-3306.2010.00312.x
Collins SN, Dyson SJ, Murray RC, Burden F, Trawford A.Anatomical change within a laminitic foot is of diagnostic and prognostic importance. A lateromedial radiograph represents the current 'gold standard' by which these changes are identified. Detection of anatomical change is dependent upon a priori knowledge of normality and subjective assessment alone may not identify modest change. Normal baseline data is, therefore, needed against which objective comparisons can be made. There is little information regarding the radiological anatomy of the donkey foot, hence an equine model has been widely adopted. However, descriptive accounts suggest funda...
Impact of successive freezing-thawing cycles on 3-T magnetic resonance images of the digits of isolated equine limbs.
American journal of veterinary research    June 2, 2011   Volume 72, Issue 6 780-790 doi: 10.2460/ajvr.72.6.780
Bolen GE, Haye D, Dondelinger RF, Massart L, Busoni V.To assess the impact of cycles of freezing and thawing on magnetic resonance (MR) images (obtained by use of a 3-T magnet) of equine feet examined ex vivo. Methods: 9 forelimbs from 9 horse cadavers. Methods: 9 forefeet underwent MR imaging first at ambient temperature within 12 hours after the horses' death and then after each freezing-thawing cycle. Three digits underwent freezing and thawing (at 4°C for 36 hours) 2 times, 3 digits underwent freezing and thawing (at 4°C for 36 hours) once and rescanning after 24 hours at ambient temperature, and 3 digits underwent freezing and thawing at a...
Sole depth and weight-bearing characteristics of the palmar surface of the feet of feral horses and domestic Thoroughbreds.
American journal of veterinary research    June 2, 2011   Volume 72, Issue 6 727-735 doi: 10.2460/ajvr.72.6.727
Hampson BA, Connelley AD, de Laat MA, Mills PC, Pollitt CC.To determine solar load-bearing structures in the feet of feral horses and investigate morphological characteristics of the sole in feral horses and domestic Thoroughbreds. Methods: Forelimbs from cadavers of 70 feral horses and 20 domestic Thoroughbreds in Australia. Methods: Left forefeet were obtained from 3 feral horse populations from habitats of soft substrate (SS [n = 10 horses]), hard substrate (HS [10]), and a combination of SS and HS (10) and loaded in vitro. Pressure distribution was measured with a pressure plate. Sole depth was measured at 12 points across the solar plane in feet ...
Comparisons of computed tomography, contrast enhanced computed tomography and standing low-field magnetic resonance imaging in horses with lameness localised to the foot. Part 1: anatomic visualisation scores.
Equine veterinary journal    May 30, 2011   Volume 44, Issue 1 51-56 doi: 10.1111/j.2042-3306.2011.00372.x
Vallance SA, Bell RJ, Spriet M, Kass PH, Puchalski SM.To date, few reports exist comparing magnetic resonance imaging (MRI) and computed tomography (CT) for imaging of the equine distal limb, yet clinicians are required to decide which modality to use regularly. Objective: To report and compare anatomic visualisation scores obtained for CT, contrast enhanced CT (CECT) and standing low-field MRI (LFMRI) in the equine foot. Objective: Anatomic visualisation score discrepancies would exist between CT, CECT and LFMRI. Methods: Images of 22 lame horses (31 limbs) undergoing both CT and LFMRI of the foot were reviewed. When available, CECT images were ...
Cartilage damage involving extrusion of mineralisable matrix from the articular calcified cartilage and subchondral bone.
European cells & materials    May 28, 2011   Volume 21 470-478 doi: 10.22203/ecm.v021a35
Boyde A, Riggs CM, Bushby AJ, McDermott B, Pinchbeck GL, Clegg PD.Arthropathy of the distal articular surfaces of the third metacarpal (Mc3) and metatarsal (Mt3) bones in the Thoroughbred racehorse (Tb) is a natural model of repetitive overload arthrosis. We describe a novel pathology that affects the articular calcified cartilage (ACC) and subchondral bone (SCB) and which is associated with hyaline articular cartilage degeneration. Parasagittal slices cut from the palmar quadrant of the distal condyles of the left Mc3/Mt3 of 39 trained Tbs euthanized for welfare reasons were imaged by point projection microradiography, and backscattered electron (BSE) scann...
Osseous spinal pathology and epaxial muscle ultrasonography in Thoroughbred racehorses.
Equine veterinary journal. Supplement    May 28, 2011   Issue 38 654-661 doi: 10.1111/j.2042-3306.2010.00258.x
Stubbs NC, Riggs CM, Hodges PW, Jeffcott LB, Hodgson DR, Clayton HM, McGowan CM.The multifidus muscle plays a key role in spinal stabilisation. Multifidus atrophy ipsilateral to the side of osseous pathology has been demonstrated in man and pigs but has not been investigated in horses. Objective: To measure cross-sectional area (CSA) left/ right symmetry of equine multifidus ultrasonographically and relate asymmetry of multifidus with osseous spinal pathology in Thoroughbred racehorses. We hypothesised that ipsilateral multifidus CSA would be reduced when osseous pathological changes are present leading to left/right asymmetry in CSA. Methods: Twenty-two racehorses presen...
The effect of ex vivo flexion and extension on intervertebral foramina dimensions in the equine cervical spine.
Equine veterinary journal. Supplement    May 27, 2011   Issue 38 425-430 doi: 10.1111/j.2042-3306.2010.00226.x
Sleutjens J, Voorhout G, Van Der Kolk JH, Wijnberg ID, Back W.In dressage, the head and neck position has become an issue of concern as certain extreme positions may imply a welfare risk for the horse. In man, extension and flexion of the cervical spine cause a decrease and increase in intervertebral foramina dimensions, respectively. However, in horses, the influence of flexion and extension on foramina dimensions and its possible interference with peripheral nerve functioning remains unknown. Objective: To determine the effect of ex vivo flexion and extension on intervertebral foramina dimensions in the equine cervical spine. Methods: Computed tomograp...
A preliminary modelling study on the equine cervical spine with inverse kinematics at walk.
Equine veterinary journal. Supplement    May 27, 2011   Issue 38 516-522 doi: 10.1111/j.2042-3306.2010.00265.x
Zsoldos RR, Groesel M, Kotschwar A, Kotschwar AB, Licka T, Peham C.The motion of the atlanto-occipital, cervical vertebral and cervicothoracic joints play an important role in equestrian sports and they are also common sites for lesions limiting performance in horses. Objective: To calculate inverse kinematics based on cervical vertebral motion and to develop a model close to the measured neck movements. Methods: Measurements were recorded in 6 horses without neck pain. Reflective markers were placed on both cristae facialis, both sides of cervical vertebra 1, 3 and 6 on the withers and hooves. The neck model was reconstructed from CT scans of the osseus stru...
Relationships between myonuclear domain size and fibre properties in the muscles of Thoroughbred horses.
Equine veterinary journal. Supplement    May 27, 2011   Issue 38 311-316 doi: 10.1111/j.2042-3306.2010.00236.x
Kawai M, Kuwano A, Hiraga A, Miyata H.The myonuclear domain (MND) is the region of cytoplasm governed by a single myonucleus. Myonuclear domain size is an important factor for muscle fibre plasticity because each myonucleus has limitations in the capacity of protein synthesis. Previous studies have demonstrated that differences in MND size exist in different fibre types in several species, including horses. Objective: To understand the basic mechanism of muscle plasticity, the relationships between MND size, muscle fibre type population and metabolic properties of skeletal muscles throughout the whole body in Thoroughbred horses w...
Electromyography activity of the equine splenius muscle and neck kinematics during walk and trot on the treadmill.
Equine veterinary journal. Supplement    May 27, 2011   Issue 38 455-461 doi: 10.1111/j.2042-3306.2010.00263.x
Zsoldos RR, Kotschwar AB, Kotschwar A, Groesel M, Licka T, Peham C.Skeletal muscle activity can be concentric or eccentric, anisometric or isometric and correlation of the equine splenius muscle activity with the movement of its effector joints at walk and trot has not yet been fully characterised. Objective: Investigating activity of the splenius muscle together with kinematics of head and cranial neck at walk and trot. Methods: Kinematics and surface electromyography were measured in 6 horses (8-20-years-old, 450-700 kg) without signs of neck pain. Markers were placed on left and right crista facialis, and on left and right cervical vertebrae 1 and 3. Head ...
Metacarpal geometry changes during Thoroughbred race training are compatible with sagittal-plane cantilever bending.
Equine veterinary journal. Supplement    May 27, 2011   Issue 38 407-411 doi: 10.1111/j.2042-3306.2010.00209.x
Merritt JS, Davies HM.Bending of the equine metacarpal bones during locomotion is poorly understood. Cantilever bending, in particular, may influence the loading of the metacarpal bones and surrounding structures in unique ways. Objective: We hypothesised that increased amounts of sagittal-plane cantilever bending may govern changes to the shape of the metacarpal bones of Thoroughbred racehorses during training. We hypothesised that this type of bending would require a linear change to occur in the combined second moment of area of the bones for sagittal-plane bending (I) during race training. Methods: Six Thorough...
A pilot study on objective quantification and anatomical modelling of in vivo head and neck positions commonly applied in training and competition of sport horses.
Equine veterinary journal. Supplement    May 27, 2011   Issue 38 436-443 doi: 10.1111/j.2042-3306.2010.00228.x
Elgersma AE, Wijnberg ID, Sleutjens J, van der Kolk JH, van Weeren PR, Back W.Head and neck positions (HNP) in sport horses are under debate in the equine community, as they could interfere with equine welfare. HNPs have not been quantified objectively and no information is available on their head and neck loading. Objective: To quantify in vivo HNPs in sport horses and develop o a model to estimate loading on the cervical vertebrae in these positions. Methods: Videos were taken of 7 Warmbloods at walk on a straight line in 5 positions, representing all HNPs during Warmblood training and competition. Markers were glued at 5 anatomical landmarks. Two-dimensional angles a...
Preliminary report into the function of the shoulder using a novel imaging and motion capture approach.
Equine veterinary journal. Supplement    May 27, 2011   Issue 38 552-555 doi: 10.1111/j.2042-3306.2010.00289.x
Lawson SE, Marlin DJ.The function of the forelimb is fundamental to understanding both sound and pathological locomotion. The precise movements of the equine shoulder are hidden by layers of skin and muscle and hence the shoulder is normally modelled as a simple pivot during locomotion which assumes that any translational motion is negligible. Objective: To record and quantify the sliding motion of the scapula during locomotion, using a novel imaging technique. Methods: Scapula motion during locomotion in the horse was calculated by tracking the ripple of the shoulder blade's movement under an array of markers pla...
Quantification of equine sacral and iliac motion during gait: a comparison between motion capture with skin-mounted and bone-fixated sensors.
Equine veterinary journal. Supplement    May 27, 2011   Issue 38 468-474 doi: 10.1111/j.2042-3306.2010.00204.x
Goff L, Van Weeren PR, Jeffcott L, Condie P, McGowan C.Information regarding movement at the ilium and sacrum in nonlame horses during normal gait may assist in understanding the biomechanics of the equine sacroiliac joint. Objective: To determine the amount and direction of motion at the ilium and sacrum using 3D orientation sensors during walk and trot in sound Thoroughbreds. To compare results from sensors fixed to the skin with results from sensors fixed to bone-implanted pins. Methods: Three 3D wireless orientation sensors were mounted to the skin over the tuber sacrale (TS) and sacrum of 6 horses and motion at the ilium and sacrum was record...
Endoscopic examination of the nasolacrimal duct in ten horses.
Equine veterinary journal    May 20, 2011   Volume 43, Issue 2 159-162 doi: 10.1111/j.2042-3306.2010.00160.x
Spadari A, Spinella G, Grandis A, Romagnoli N, Pietra M.No endoscopic examination of the nasolacrimal duct has been described before. In contrast with other imaging techniques, endoscopy provides a direct inspection of the intralumen and ductal mucosa in standing sedation. Objective: To provide a reference against which the endoscopic and clinical features of obstructive nasolacrimal disease in the horse may be compared. Methods: Endoscopic examination of the nasolacrimal duct was performed in 10 French Thoroughbred bay mares with a 3 mm shaft diameter flexible fibrescope. The duct was divided into 3 zones (1, 2 and 3) from the nostril to the lacri...
Positive contrast magnetic resonance bursography for assessment of the navicular bursa and surrounding soft tissues. Maher MC, Werpy NM, Goodrich LR, McIlwraith CW.Magnetic resonance (MR) imaging is often performed to determine the cause of palmar heel pain. We evaluated how distension of the navicular bursa affected the MR appearance of the navicular bursa and associated structures. An MR evaluation was performed on normal cadaver limbs and cadaver limbs from horses with lameness localized to the foot. The normal navicular bursae were injected with 2, 4, or 6 ml of solution. The bursae of the feet from lame horses were injected with 4 or 6 ml, and the MR study was repeated. All bursae were examined grossly to verify the presence or absence of adhesions....
Fractures of the distal phalanx and associated soft tissue and osseous abnormalities in 22 horses with ossified sclerotic ungual cartilages diagnosed with magnetic resonance imaging. Selberg K, Werpy N.Ungual cartilage ossification in the forelimb is a common finding in horses. Subtle abnormalities associated with the ungual cartilages can be difficult to identify on radiographs. Magnetic resonance (MR) imaging findings of 22 horses (23 forelimbs) with a fracture of the distal phalanx and ossified ungual cartilage were characterized and graded. All horses had a forelimb fracture. Eleven involved a left forelimb (seven medial; four lateral), and 12 involved a right forelimb (five medial; seven lateral). All fractures were nonarticular, simple in configuration, and nondisplaced. The fractures ...
Analysis of conformational variations of the cricoid cartilages in Thoroughbred horses using computed tomography.
Equine veterinary journal    May 20, 2011   Volume 43, Issue 2 229-234 doi: 10.1111/j.2042-3306.2010.00070.x
Dahlberg JA, Valdes-Martinez A, Boston RC, Parente EJ.Loss of arytenoid abduction is a common post operative complication of laryngoplasty without a definitive cause. It has been a clinical impression during laryngoplasty surgery that there is great conformational variability along the caudal edge of the Thoroughbred cricoid cartilage that could impact post operative retention of suture position. A change in suture position would probably lead to some loss of abduction. Defining any structural variability of the cricoid would be an initial step in determining whether this variability could impact on the retention of suture position. Objective: An...
An anatomical study to evaluate the risk of pulpar exposure during mechanical widening of equine cheek teeth diastemata and ‘bit seating’.
Equine veterinary journal    May 20, 2011   Volume 43, Issue 2 163-169 doi: 10.1111/j.2042-3306.2010.00138.x
Bettiol N, Dixon PM.Cheek teeth (CT) diastemata are a major equine dental disorder that can be treated by mechanically widening the diastemata. There is limited anatomical knowledge of the spatial relationships of the individual pulps to the adjacent interproximal surfaces; on the risks of exposing the 6th pulp horn when performing the clinically unproven 'bit seating' procedure on Triadan 06s. Objective: To describe the anatomical relationships between the occlusal and interproximal surfaces of CT and the adjacent pulp horns; and between the 6th pulp horn and the occlusal and rostral surfaces of Triadan 06s. Met...
Evaluation of the Perkins handheld applanation tonometer in horses and cattle.
Journal of veterinary science    May 19, 2011   Volume 12, Issue 2 171-176 doi: 10.4142/jvs.2011.12.2.171
Andrade SF, Kupper DS, Pinho LF, Franco EC, Prataviera MV, Duarte RR, Junqueira JR.The objective of this study was to evaluate and validate the accuracy of the Perkins handheld applanation tonometer for measuring intraocular pressure (IOP) in horses and cattle. Both eyes of 10 adult horses and cattle were evaluated in a postmortem study. The eyes from 10 clinically normal adult horses and cattle were also examined after bilateral auriculopalpebral nerve block and topical anesthesia for an in vivo study. IOP was measured postmortem using direct manometry (measured with an aneroid manometer) and tonometry (measured with a Perkins handheld applanation tonometer). The correlatio...
Biomechanical characterisation of equine laryngeal cartilage.
Equine veterinary journal    May 5, 2011   Volume 43, Issue 5 592-598 doi: 10.1111/j.2042-3306.2010.00315.x
Passman SN, Cheetham J, Bonassar LJ, Ducharme NG, Rawlinson JJ.Upper airway obstruction is a common problem in the performance horse as the soft tissues of the larynx collapse into the airway, yet there is a paucity of information on biomechanical properties for the structural cartilage components. Objective: To measure the geometry and compressive mechanical properties of the hyaline cartilage to improve understanding of laryngeal function and morphology. Methods: A total of 11 larynges were harvested from Thoroughbred and Standardbred racehorses. During gross dissection, linear dimensions of the cricoid were obtained. From both the cricoid and arytenoid...
Internal fixation of a fractured axis in an adult horse.
Veterinary surgery : VS    May 4, 2011   Volume 40, Issue 5 636-640 doi: 10.1111/j.1532-950X.2011.00842.x
Gygax D, Fürst A, Picek S, Kummer M.To report internal fixation of a fractured axis with a dynamic compression plate (DCP). Methods: Case report. Methods: A 7-year-old Warmblood gelding. Methods: Surgery was performed under anesthesia in sternal recumbency. After fracture reduction the complete transverse fracture in the cranial third of the axis was stabilized with a 7-hole 4.5 mm DCP. Optimal positioning of the plate and the length of the screws were facilitated by fluoroscopy. Recovery from anesthesia was supervised in a pool. Results: The horse had an excellent outcome and returned to its previous activity level. Conclusions...
Syringohydromyelia in horses: 3 cases.
The Canadian veterinary journal = La revue veterinaire canadienne    May 3, 2011   Volume 52, Issue 2 147-152 
Sponseller BA, Sponseller BT, Alcott CJ, Kline K, Hostetter J, Reinertson EL, Fales-Williams A.Syringomyelia and hydromyelia are cavitary lesions of the spinal cord that may be acquired or congenital. These lesions are not frequently reported in large animal species. The presenting complaints, clinical, gross pathological, and histopathologic findings of 2 cases of syringomyelia and 1 case of hydromyelia in horses are described. La syringomyélie et l’hydromyélie sont des lésions cavitaires de la colonne vertébrale qui peuvent être acquises ou congénitales. Ces lésions ne sont pas fréquemment signalées chez les espèces de grands animaux. Les plaintes de présentation et les ...
Expression of cyclooxygenase genes in the jejunum of horses during low-flow ischemia and reperfusion.
American journal of veterinary research    May 3, 2011   Volume 72, Issue 5 681-686 doi: 10.2460/ajvr.72.5.681
Hilton H, Nieto JE, Moore PF, Harmon FA, Naydan DK, Snyder JR.To determine expression of cyclooxygenase (COX) genes 1 and 2 (also called prostaglandin-endoperoxide synthases 1 and 2) and stability of housekeeping gene expression during low-flow ischemia and reperfusion in the jejunum of horses. Methods: 5 healthy adult horses. Methods: Horses were anesthetized, and two 30-cm segments of jejunum were surgically exteriorized. Blood flow was maintained at baseline (untreated) values in 1 (control) segment and was decreased to 20% of baseline (low-flow ischemia) for 75 minutes, followed by 75 minutes of reperfusion, in the other (experimental) segment. Biops...
In vitro biomechanical comparison of dynamic compression plates with a rough contact surface and a polished contact surface for fixation of osteotomized equine third metacarpal bones.
Veterinary surgery : VS    May 3, 2011   Volume 40, Issue 5 579-585 doi: 10.1111/j.1532-950X.2011.00833.x
Sod GA, Riggs LM, Mitchell CF, Martin GS, Gill MS.To compare the number of cycles to failure of 4.5 mm broad dynamic compression plates (DCP), 4.5 mm broad limited-contact dynamic compression plates (4.5-LC-DCP), and 5.5 mm broad limited-contact dynamic compression plates (5.5-LC-DCP) having a rough (denoted by a prefix R-) versus a standard smooth contact surface for the fixation of osteotomized equine 3rd metacarpal (MC3) bones. Methods: Experimental. Methods: Fifteen pairs of adult equine cadaveric MC3 bones. Methods: Fifteen pairs of equine MC3 were divided into 3 test groups (5 pairs each) for comparison of (1) R-DCP fixation with DCP fi...
The impact of ultrasound during emergency after-hour admissions of horses.
Journal of the South African Veterinary Association    April 30, 2011   Volume 81, Issue 4 216-218 doi: 10.4102/jsava.v81i4.150
Viljoen A, Saulez MN, Carstens A, Gummow B.Clinical use of diagnostic ultrasound at point-of-care or emergency situations, although common, has not been well documented in veterinary medicine. Medical records of after-hour emergency equine admissions during a 10-year period were reviewed and horses that received ultrasound scans were identified. Data sheets for each ultrasound scan performed during emergency clinical evaluation were collected and reviewed. Data extracted included anatomical region imaged, body system affected, documented ultrasonographic diagnosis and final diagnosis. Six hundred and nine records were available of whic...
Toxic equine parkinsonism: an immunohistochemical study of 10 horses with nigropallidal encephalomalacia.
Veterinary pathology    April 28, 2011   Volume 49, Issue 2 398-402 doi: 10.1177/0300985811406885
Chang HT, Rumbeiha WK, Patterson JS, Puschner B, Knight AP.Chronic ingestion of yellow star thistle (Centaurea solstitialis) or Russian knapweed (Acroptilon repens) causes nigropallidal encephalomalacia (NPE) in horses with an abrupt onset of neurologic signs characterized by dystonia of lips and tongue, inability to prehend food, depression, and locomotor deficits. The objectives of this study were to reexamine the pathologic alterations of NPE and to conduct an immunohistochemistry study using antibodies to tyrosine hydroxylase and α-synuclein, to determine whether NPE brains show histopathologic features resembling those in human Parkinson disease...
A mechanical comparison of equine proximal interphalangeal joint arthrodesis techniques: an axial locking compression plate and two abaxial transarticular cortical screws versus an axial dynamic compression plate and two abaxial transarticular cortical screws.
Veterinary surgery : VS    April 26, 2011   Volume 40, Issue 5 571-578 doi: 10.1111/j.1532-950X.2011.00830.x
Sod GA, Riggs LM, Mitchell CF, Martin GS.To compare in vitro monotonic biomechanical properties of an axial 3-hole, 4.5 mm narrow locking compression plate (ELCP) using 5.0 mm locking screws and 5.5 mm cortical screws in conjunction with 2 abaxial transarticular 5.5 mm cortical screws inserted in lag fashion (ELCP-TLS) with an axial 3-hole, 4.5 mm narrow dynamic compression plate (DCP) using 5.5 mm cortical screws in conjunction with 2 abaxial transarticular 5.5 mm cortical screws inserted in lag fashion (DCP-TLS) for equine proximal interphalangeal (PIP) joint arthrodesis. Methods: Experimental. Methods: Cadaveric adult equine forel...
Evaluation of four techniques for injecting the trochanteric bursa of horses.
Veterinary surgery : VS    April 26, 2011   Volume 40, Issue 4 489-493 doi: 10.1111/j.1532-950X.2011.00828.x
Tóth F, Schumacher J, Schramme M, Hecht S.To describe the anatomic features of the equine trochanteric bursa and to evaluate 4 techniques for bursa centesis. Methods: Prospective, randomized design. Methods: Equine cadavers (n=2) and 20 live horses. Methods: The trochanteric bursae of 2 equine cadavers were injected with latex to identify the boundaries of the bursae. Four techniques for centesis of the trochanteric bursa were evaluated by attempting to inject dye into both trochanteric bursae of 20 live horses. Techniques included injection of the bursa with the limb-bearing weight and injection with the limb nonweight bearing and su...
Spinal epidermoid cyst in a SJL mouse: case report and literature review.
Journal of comparative pathology    April 20, 2011   Volume 145, Issue 4 373-377 doi: 10.1016/j.jcpa.2011.03.002
Hansmann F, Herder V, Ernst H, Baumgärtner W.This report is the first description of a spinal epidermoid cyst (EC) in a SJL mouse and gives an overview on the occurrence of ECs in animals including dogs, horses, mice and rats. The EC was not detected grossly and the mouse did not display clinical signs or an altered rotarod performance. Microscopically, there was an oval cyst lined by stratified squamous epithelium that was attached to the dorsolateral meninges and caused moderate compression of the adjacent lumbar spinal cord. ECs in mice and rats are mainly located in the caudal part of the spinal cord with a variable, strain-dependent...
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