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Topic:Animal Health

Animal Health encompasses a broad range of topics focused on maintaining and improving the well-being of equine species. This field addresses various aspects of horse care, including disease prevention, diagnosis, treatment, and management of health conditions. Key areas of interest include equine nutrition, vaccination protocols, parasite control, dental care, and the management of chronic conditions such as laminitis and colic. Additionally, animal health research in horses investigates the impact of exercise and training on physical health, the role of genetics in disease susceptibility, and the development of new therapeutic approaches. This page compiles peer-reviewed research studies and scholarly articles that explore the latest advancements, challenges, and best practices in preserving and enhancing the health of horses.
Traditional knowledge about plant, animal, and mineral-based remedies to treat cattle, pigs, horses, and other domestic animals in the Mediterranean island of Sardinia.
Journal of ethnobiology and ethnomedicine    July 20, 2018   Volume 14, Issue 1 50 doi: 10.1186/s13002-018-0250-7
Bullitta S, Re GA, Manunta MDI, Piluzza G.Mediterranean farmers traditionally utilized plants, animals, and minerals sourced locally to treat their animals. Research is needed to understand at what extent such knowledge of domestic animal care still survives and to document such traditions for further developments. Methods: We carried out our field study to recover ancient ethno-veterinary practices by means of questionnaires and interviews to farmers in rural areas of the Mediterranean island of Sardinia (Italy). Quantitative indices were used to evaluate the distribution and diversity of the acquired information. Results: We report ...
Circannual variability in adrenocorticotropic hormone responses to administration of thyrotropin-releasing hormone in clinically normal horses in Australia.
Veterinary journal (London, England : 1997)    July 19, 2018   Volume 238 58-62 doi: 10.1016/j.tvjl.2018.07.008
Byrne DP, Secombe CJ, Tan RHH, Perera DI, Watts SP, Wearn JG.Thyrotropin releasing hormone (TRH)-stimulation testing for pituitary pars intermedia dysfunction (PPID) in horses is only recommended at certain times of the year. Current diagnostic cut-off values reflect testing in the northern hemisphere during this time. The aims of this study were to evaluate TRH stimulation testing during two different phases of the circannual pituitary cycle and to determine whether diagnostic cut-off values developed in the northern hemisphere are appropriate in Australia. Thirteen clinically normal horses at Perth, Western Australia, and 23 horses at Townsville, Quee...
Heart valve pathology in regularly slaughtered horses.
Veterinaria italiana    July 19, 2018   Volume 54, Issue 2 165-168 doi: 10.12834/VetIt.1394.7616.1
Passantino G, Scaglione FE, Zizzo N, Leone R, Guarda F.In this study we examined macroscopic and microscopic lesions in the mitral valves of 50 regularly slaughtered horses in Italy. Macroscopically the results were minor. Microscopic lesions to the valve were found in both young and elderly subjects, confirming that there is no correlation between age and onset of lesions. We set out to evaluate whether the lesions correspond to valve disorder during the life of the animal.
Survey of human-horse relationships and veterinary care for geriatric horses.
Journal of the American Veterinary Medical Association    July 19, 2018   Volume 253, Issue 3 337-345 doi: 10.2460/javma.253.3.337
Mueller MK, Sween C, Frank N, Paradis MR.OBJECTIVE To assess relationships between horse owners (or lessees) and geriatric or nongeriatric horses and to investigate factors influencing veterinary care decision-making. DESIGN Descriptive, cross-sectional, survey-based study. SAMPLE 2,879 people who owned or leased ≥ 1 horse. PROCEDURES Participants were recruited through social media and online horse forums to participate in an online survey about their horses, including measures of attachment, veterinary care decision-making, and experiences surrounding the death of a horse. Data were collected for primary horses (those respondents...
Effect of antigen challenge on dynamics of CD62P and CD41/61 expression on platelets in horses with recurrent airway obstruction (RAO).
Veterinary immunology and immunopathology    July 18, 2018   Volume 202 172-180 doi: 10.1016/j.vetimm.2018.07.007
Iwaszko A, Borowicz H, Graczyk S, Slowikowska M, Pliszczak-Krol A, Niedzwiedz A.Recurrent airway obstruction (RAO), also known as heaves, is an allergic respiratory condition that develops in horses following an exposure to aeroallergens in hay and straw. This is manifested by airway hyperreactivity, inflammation, bronchoconstriction, as well as a leukocyte and platelet infiltration into the airways. Platelet activation and an increase in circulating platelet-leukocyte aggregates may lead to airway remodeling. The aim of this study was to explore the effect of seven-day antigen challenge on dynamics of platelet indices and CD41/61 and CD62 P expression on platelets in h...
Molecular survey and characterization of Trypanosoma evansi in naturally infected camels with suspicion of a Trypanozoon infection in horses by molecular detection in Egypt.
Microbial pathogenesis    July 18, 2018   Volume 123 201-205 doi: 10.1016/j.micpath.2018.07.017
Elhaig MM, Sallam NH.In Egypt, although the Trypanosoma evansi has been reported frequently among domestic animals, there is no published data on T. evansi in horses. Therefore, this study aimed to assess the prevalence and characterization of T. evansi in three governorates by examining blood samples from 40 local camels, 35 imported camels, 25 horses and 10 donkeys by PCR targeting the sequences of TBR and RoTat 1.2VSG. The overall prevalence of T. evansi was 54.5% and 21.8% by TBR PCR and RoTat 1.2VSG PCR, respectively. The TBR PCR detected T. evansi in 60% and 71.4%, respectively, of local and imported camels ...
Impact of Trendelenburg (head down) and reverse Trendelenburg (head up) position on respiratory and cardiovascular function in anaesthetized horses.
Veterinary anaesthesia and analgesia    July 18, 2018   Volume 45, Issue 6 760-771 doi: 10.1016/j.vaa.2018.01.012
Binetti A, Mosing M, Sacks M, Duchateau L, Gasthuys F, Schauvliege S.To describe the cardiorespiratory effects of a change in table position in anaesthetized horses. Methods: Prospective, crossover, randomized, experimental study. Methods: Six adult horses (mean body weight 621 ± 59 kg, aged 13 ± 4 years). Methods: The horses were anaesthetized twice in dorsal recumbency. They were either placed in the Trendelenburg position (head down; HD) followed by reverse Trendelenburg position (head up; HU) or in reverse order. Every position was maintained for 90 minutes. The order of positions was randomly assigned at initial anaesthesia. Extensive cardiorespiratory m...
Equine Sports Medicine: Our Daily Challenge.
The Veterinary clinics of North America. Equine practice    July 17, 2018   Volume 34, Issue 2 xiii-xiv doi: 10.1016/j.cveq.2018.05.001
García-López JM.No abstract available
Understanding the Basic Principles of Podiatry.
The Veterinary clinics of North America. Equine practice    July 17, 2018   Volume 34, Issue 2 391-407 doi: 10.1016/j.cveq.2018.04.015
Bras RJ, Redden R.Foot-related lameness is one of the most frequently encountered problems in the equine industry. Therapeutic shoeing is a frequently used preventative discipline for the treatment of many causes of lameness. The primary goal for therapeutic applications is to offset the mechanical limitations and enhance the healing environment. Equine podiatry is a blend of the 2 highly respected professions each contributing to the task at hand, but neither formally educated and trained as collaborative team members with a common thread of podiatry principles.
Borreliosis in Sport Horse Practice.
The Veterinary clinics of North America. Equine practice    July 17, 2018   Volume 34, Issue 2 313-343 doi: 10.1016/j.cveq.2018.04.011
Swinebroad EL.Given the variable clinical signs attributed to Borrelia burgdorferi, including infectious arthritis, neurologic disease, and behavioral changes, B burgdorferi is an important differential for decreased performance in sport horses. The primary vectors (Ixodes tick species) are expanding their range and thus Borrelia species are located in a wider area, making exposure more likely. Due to regionally high seroprevalence and vague clinical signs, diagnosis of Lyme disease in the horse is believed overestimated. Antibiotics are first-line treatment of confirmed Lyme disease. A single positive sero...
Could the Visual Differential Attention Be a Referential Gesture? A Study on Horses (Equus caballus) on the Impossible Task Paradigm.
Animals : an open access journal from MDPI    July 17, 2018   Volume 8, Issue 7 120 doi: 10.3390/ani8070120
Alterisio A, Baragli P, Aria M, D'Aniello B, Scandurra A.In order to explore the decision-making processes of horses, we designed an impossible task paradigm aimed at causing an expectancy violation in horses. Our goals were to verify whether this paradigm is effective in horses by analyzing their motivation in trying to solve the task and the mode of the potential helping request in such a context. In the first experiment, 30 horses were subjected to three consecutive conditions: no food condition where two persons were positioned at either side of a table in front of the stall, solvable condition when a researcher placed a reachable reward on the ...
Lameness Evaluation of the Athletic Horse.
The Veterinary clinics of North America. Equine practice    July 17, 2018   Volume 34, Issue 2 181-191 doi: 10.1016/j.cveq.2018.04.013
Davidson EJ.Lameness examination is commonly performed in the athletic horse. A skilled lameness diagnostician must have keen clinical and observational skills. Evaluation starts with a detailed history and thorough physical examination. Next, gait evaluation in the moving horse is performed. Lame horses have asymmetrical body movement due to unconscious shift of body weight. Recognition of the resultant head nod and pelvic hike is the basis for lameness diagnosis. Lameness identification is enhanced by circling, limb flexions, and riding. Most lame horses do not exhibit pathognomonic gait characteristics...
Lower Airway Disease in the Athletic Horse.
The Veterinary clinics of North America. Equine practice    July 17, 2018   Volume 34, Issue 2 443-460 doi: 10.1016/j.cveq.2018.04.010
Mazan MR.The airways are the first part of the pathway in the oxygen transport chain that is critical to excellent athletic performance, and the lower airways are considered the final gatekeeper before oxygen enters the blood and carbon dioxide exits. Horses are blessed with large airways and lungs that allow them to be superb athletes, but the down side of this largesse on the part of evolution is that unless they are truly elite athletes they may withstand noninfectious disease of the lower respiratory tract for months to years before the owner or trainer notices. The two conditions of the lower resp...
Genetic risk for squamous cell carcinoma of the nictitating membrane parallels that of the limbus in Haflinger horses.
Animal genetics    July 12, 2018   Volume 49, Issue 5 457-460 doi: 10.1111/age.12695
Singer-Berk M, Knickelbein KE, Vig S, Liu J, Bentley E, Nunnery C, Reilly C, Dwyer A, Drögemüller C, Unger L, Gerber V, Lassaline M, Bellone RR.Squamous cell carcinoma (SCC) is the most common cancer affecting the equine eye, with a higher incidence documented in Haflinger horses. Recently, a missense variant in the gene damage specific DNA binding protein 2 (DDB2, p.Thr338Met) on ECA12 was identified as a risk factor for the development of limbal SCC in Haflinger horses. SCC also occurs on the nictitating membrane; therefore, investigating the role of this missense variant in nictitating membrane SCC is warranted. In this study, a common ancestor was identified among Haflinger horses affected with limbal SCC or with nictitating membr...
Combination of resveratrol and 5-azacytydine improves osteogenesis of metabolic syndrome mesenchymal stem cells.
Journal of cellular and molecular medicine    July 12, 2018   Volume 22, Issue 10 4771-4793 doi: 10.1111/jcmm.13731
Marycz K, Kornicka K, Irwin-Houston JM, Weiss C.Endocrine disorders have become more and more frequently diagnosed in humans and animals. In horses, equine metabolic syndrome (EMS) is characterized by insulin resistance, hyperleptinemia, hyperinsulinemia, inflammation and usually by pathological obesity. Due to an increased inflammatory response in the adipose tissue, cytophysiological properties of adipose derived stem cells (ASC) have been impaired, which strongly limits their therapeutic potential. Excessive accumulation of reactive oxygen species, mitochondria deterioration and accelerated ageing of those cells affect their multipotency...
Prevalence of complications associated with use of the Henderson equine castrating instrument.
Equine veterinary journal    July 12, 2018   Volume 51, Issue 2 163-166 doi: 10.1111/evj.12982
Hinton S, Schroeder O, Aceto HW, Berkowitz S, Levine D.Castration is one of the most common surgical procedures performed in the horse. Complication rate and types of complications associated with use of the Henderson equine castrating instrument have not been determined. Objective: To determine the complication rate and type of complications encountered when using the Henderson equine castrating instrument in equine ambulatory practice. Methods: Retrospective case series. Methods: Medical records of horses undergoing routine castration using the Henderson drill were identified and evaluated for the occurrence of complications. The relationship be...
Molecular identification of Trichomonas tenax in the oral environment of domesticated animals in Poland – potential effects of host diversity for human health.
Annals of agricultural and environmental medicine : AAEM    July 12, 2018   Volume 25, Issue 3 464-468 doi: 10.26444/aaem/92309
Dybicz M, Perkowski K, Baltaza W, Padzik M, Sędzikowska A, Chomicz L.The protozoan is considered to be a human specific flagellate of the oral cavity, found in humans with poor oral hygiene and advanced periodontal disease. Morphological variability and great similarity between species occurring in humans and animals, complicate the specific identification of trichomonads, using microscopic examination and other standard parasitological techniques. Objective: The aim of the study was to search for and identify in domesticated animals using molecular methods. The obtained data were assessed in terms of potential effects of a spread of the species deriving from...
An unexpected acoustic indicator of positive emotions in horses.
PloS one    July 11, 2018   Volume 13, Issue 7 e0197898 doi: 10.1371/journal.pone.0197898
Stomp M, Leroux M, Cellier M, Henry S, Lemasson A, Hausberger M.Indicators of positive emotions are still scarce and many proposed behavioural markers have proven ambiguous. Studies established a link between acoustic signals and emitter's internal state, but few related to positive emotions and still fewer considered non-vocal sounds. One of them, the snort, is shared by several perrisodactyls and has been associated to positive contexts in these species. We hypothesized that this could be also the case in horses. In this species, there is a clear need for a thorough description of non-vocal acoustic signals (snorts, snores or blows are often used interch...
Physiological costs of infection: herpesvirus replication is linked to blood oxidative stress in equids.
Scientific reports    July 9, 2018   Volume 8, Issue 1 10347 doi: 10.1038/s41598-018-28688-0
Costantini D, Seeber PA, Soilemetzidou SE, Azab W, Bohner J, Buuveibaatar B, Czirják GÁ, East ML, Greunz EM, Kaczensky P, Lamglait B, Melzheimer J....Viruses may have a dramatic impact on the health of their animal hosts. The patho-physiological mechanisms underlying viral infections in animals are, however, not well understood. It is increasingly recognized that oxidative stress may be a major physiological cost of viral infections. Here we compare three blood-based markers of oxidative status in herpes positive and negative individuals of the domestic horse (Equus ferus caballus) and of both captive and free-ranging Mongolian khulan (Equus hemionus hemionus) and plains zebra (Equus quagga). Herpes positive free-ranging animals had signifi...
Infectivity and virulence of Trypanosoma evansi and Trypanosoma equiperdum Venezuelan strains from three different host species.
Veterinary parasitology, regional studies and reports    July 9, 2018   Volume 13 205-211 doi: 10.1016/j.vprsr.2018.07.004
Perrone T, Sánchez E, Hidalgo L, Mijares A, Balzano-Nogueira L, Gonzatti MI, Aso PM.The infectivity and virulence of seven Trypanosoma evansi and Trypanosoma equiperdum Venezuelan strains isolated from horses, donkeys and capybaras were compared in a mouse model up to 41 days, for parasitemia, animal weight, survival rates, packed cell volume, haemoglobin and erythrocyte count. Two T. equiperdum strains and three of the T. evansi strains resulted in 100% mice mortality, while the two T. evansi donkey strains exhibited lower infectivity and mortality. T. equiperdum strains had shorter pre-patent periods (4 days) than the T. evansi strains (4-12 days). In terms of pathoge...
Rifaximin anti-inflammatory activity on bovine endometrium primary cell cultures: a preliminary study.
Veterinary medicine and science    July 9, 2018   Volume 4, Issue 4 326-332 doi: 10.1002/vms3.115
Flammini L, Mantelli L, Volpe A, Domenichini G, Di Lecce R, Dondi M, Cantoni AM, Barocelli E, Quintavalla F.Rifaximin is an unabsorbed oral antibiotic showing anti-inflammatory properties in human pathologies like irritable bowel syndrome and inflammatory bowel disease. In veterinary medicine, rifaximin is primarily used in the treatment of dermatological diseases in all animal species, in therapy and prophylaxis of mastitis in cows and in the treatment of endometritis in cattle and horses. The aim of this preliminary study was to evaluate the anti-inflammatory properties of rifaximin on primary cell cultures from bovine endometrium in which inflammatory response was induced by Lipopolysaccaride (LP...
Expression of activin receptors in the equine uteroplacental tissue: an immunohistochemical analysis.
Journal of equine science    July 6, 2018   Volume 29, Issue 2 33-37 doi: 10.1294/jes.29.33
Kimura Y, Sasaki M, Watanabe K, Dhakal P, Sato F, Taya K, Nambo Y.Activin is secreted from equine uterine glands and plays important roles in establishment and maintenance of pregnancy in mares. This study aimed to localize activin receptors (ActRs) IA/B and IIA/B using immunohistochemistry in the uteroplacental tissues of seven pregnant Thoroughbred mares. At the time of tissue collection, the mares were at the following days of pregnancy: 88, 120, 161, 269, 290, 313, and 335 days. We fixed the uteroplacental tissues in 4% paraformaldehyde and obtained serial sections that were subsequently stained for analysis. All four isoforms of ActR were expressed in t...
The effect of administration of fenbendazole on the microbial hindgut population of the horse.
Journal of equine science    July 6, 2018   Volume 29, Issue 2 47-51 doi: 10.1294/jes.29.47
Crotch-Harvey L, Thomas LA, Worgan HJ, Douglas JL, Gilby DE, McEwan NR.Anthelmintics are used as anti-worming agents. Although known to affect their target organisms, nothing has been published regarding their effect on other digestive tract organisms or on metabolites produced by them. The current work investigated effects of fenbendazole, a benzimidazole anthelmintic, on bacteria and ciliates in the equine digestive tract and on and their major metabolites. Animals receiving anthelmintic treatment had high faecal egg counts relative to controls. Analysis was performed over two weeks, with temporal differences detected in bacterial populations but with no other ...
Hair histology as a tool for forensic identification of some domestic animal species.
EXCLI journal    July 6, 2018   Volume 17 663-670 doi: 10.17179/excli2018-1478
Ahmed YA, Ali S, Ghallab A.Animal hair examination at a criminal scene may provide valuable information in forensic investigations. However, local reference databases for animal hair identification are rare. In the present study, we provide differential histological analysis of hair of some domestic animals in Upper Egypt. For this purpose, guard hair of large ruminants (buffalo, camel and cow), small ruminants (sheep and goat), equine (horse and donkey) and canine (dog and cat) were collected and comparative analysis was performed by light microscopy. Based on the hair cuticle scale pattern, type and diameter of the me...
Anthelmintic efficacy against equine strongyles in the United States.
Veterinary parasitology    July 6, 2018   Volume 259 53-60 doi: 10.1016/j.vetpar.2018.07.003
Nielsen MK, Branan MA, Wiedenheft AM, Digianantonio R, Scare JA, Bellaw JL, Garber LP, Kopral CA, Phillippi-Taylor AM, Traub-Dargatz JL.Equine strongyle parasites are ubiquitous in grazing equids across the world. Anthelmintic resistance is widely developed in cyathostomin populations, but very few surveys have evaluated anthelmintic efficacy in equine populations in the United States, and most of these are over 15 years old. The present study was carried out as part of the National Animal Health Monitoring Systems (NAHMS) Equine 2015-2016 study. The aims were to investigate anthelmintic treatment efficacy by means of the fecal egg count reduction test (FECRT) and identify parameters associated with decreased efficacy. Data we...
Effect of prolonged submaximal exercise on serum oxidative stress biomarkers (d-ROMs, MDA, BAP) and oxidative stress index in endurance horses.
BMC veterinary research    July 6, 2018   Volume 14, Issue 1 216 doi: 10.1186/s12917-018-1540-y
Brkljača Bottegaro N, Gotić J, Šuran J, Brozić D, Klobučar K, Bojanić K, Vrbanac Z.Oxidative stress (OS) associated with an intense exercise may have a negative influence on equine health. The aim of this study was to determine the effects of endurance races on oxidative and antioxidative status of horses by evaluating changes in reactive oxygen metabolites (d-ROMs), malondialdehyde (MDA), biological antioxidant potential (BAP) and oxidative stress index (OSI) values. The study was carried out on 53 race starts (28 individual horses) competing at different endurance races according to distance (40 and 80 km) and difficulty (easy and demanding). Blood samples were taken befo...
Treating insect bite hypersensitivity in horses by using active vaccination against IL-5.
The Journal of allergy and clinical immunology    July 5, 2018   Volume 142, Issue 4 1060-1061 doi: 10.1016/j.jaci.2018.06.031
Wu AY, Sur S, Grant JA.No abstract available
An unexpected diagnosis in a cat with sudden lameness.
The Journal of small animal practice    July 4, 2018   doi: 10.1111/jsap.12899
Erickson NA, Münzer B, Dunkel M, Mundhenk L.No abstract available
Development and evaluation of recombinant antigen and monoclonal antibody based competition ELISA for the sero- surveillance of surra in animals.
Journal of immunological methods    July 3, 2018   Volume 460 87-92 doi: 10.1016/j.jim.2018.06.013
Sengupta PP, Rudramurthy GR, Ligi M, Jacob SS, Rahman H, Roy P.Trypanosoma evansi, a haemoflagellated protozoan parasite, is responsible for chronic as well as the acute debilitating disease called surra in a wide range of herbivores and carnivores including domestic and wild animals. Since the parasite is having wide host range, there is a need for diagnostic test which can detect the T. evansi specific antibody in different species of animals for generating sero-surveillance data. In the present study we developed and evaluated competitive enzyme immunoassay using monoclonal antibodies (MAbs) raised against recombinant variable surface glycoprotein (rVS...
GWAS by GBLUP: Single and Multimarker EMMAX and Bayes Factors, with an Example in Detection of a Major Gene for Horse Gait.
G3 (Bethesda, Md.)    July 2, 2018   Volume 8, Issue 7 2301-2308 doi: 10.1534/g3.118.200336
Legarra A, Ricard A, Varona L.Bayesian models for genomic prediction and association mapping are being increasingly used in genetics analysis of quantitative traits. Given a point estimate of variance components, the popular methods SNP-BLUP and GBLUP result in joint estimates of the effect of all markers on the analyzed trait; single and multiple marker frequentist tests (EMMAX) can be constructed from these estimates. Indeed, BLUP methods can be seen simultaneously as Bayesian or frequentist methods. So far there is no formal method to produce Bayesian statistics from GBLUP. Here we show that the Bayes Factor, a commonly...