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Topic:Animal Health

Animal Health encompasses a broad range of topics focused on maintaining and improving the well-being of equine species. This field addresses various aspects of horse care, including disease prevention, diagnosis, treatment, and management of health conditions. Key areas of interest include equine nutrition, vaccination protocols, parasite control, dental care, and the management of chronic conditions such as laminitis and colic. Additionally, animal health research in horses investigates the impact of exercise and training on physical health, the role of genetics in disease susceptibility, and the development of new therapeutic approaches. This page compiles peer-reviewed research studies and scholarly articles that explore the latest advancements, challenges, and best practices in preserving and enhancing the health of horses.
Comparison of nociceptive withdrawal reflexes and recruitment curves between the forelimbs and hind limbs in conscious horses.
American journal of veterinary research    June 28, 2003   Volume 64, Issue 6 700-707 doi: 10.2460/ajvr.2003.64.700
Spadavecchia C, Arendt-Nielsen L, Andersen OK, Spadavecchia L, Doherr M, Schatzmann U.To compare nociceptive withdrawal reflexes (NWRs) evoked from the distal aspect of the left forelimb and hind limb in conscious standing horses and to investigate NWR recruitment for graded electrical stimulation intensities. Methods: 20 adult horses. Methods: Surface electromyographic (EMG) activity evoked by transcutaneous electrical stimulation of the digital palmar (or plantar) nerve was recorded from the common digital extensor and cranial tibial muscles. Stimuli consisted of 25-millisecond train-of-5 constant current pulses. Current intensity was gradually increased until NWR threshold i...
Genetic polymorphism of the serum proteins of horses in Jeju.
Journal of veterinary science    June 24, 2003   Volume 3, Issue 4 255-263 
Shin JA, Yang YH, Kim HS, Yun YM, Lee KK.The study was carried out to investigate the genetic polymorphism of the serum proteins of horses in Cheju. They were assigned to three groups; 45 Cheju native horses(CNH), 60 Cheju racing horses(CRH) and 60 Thoroughbreds(TB). We analyzed the phenotypes and gene frequencies of serum proteins which were albumin (Alb), vitamin-D binding protein(GC), esterase (ES), A1B glycoprotein(A1B) and transferrin(TF) loci using horizontal polyacrylamide gel electrophoresis (HPAGE). All of the loci, except A1B in TB, showed polymorphisms and different allelic and phenotypic frequencies in all three groups. E...
Activities of enzymes in the malate-aspartate shuttle and the isoenzyme pattern of lactate dehydrogenase in plasma and peripheral leukocytes of lactating Holstein cows and riding horses.
Research in veterinary science    June 13, 2003   Volume 75, Issue 1 15-19 doi: 10.1016/s0034-5288(03)00039-0
Arai T, Inoue A, Uematsu Y, Sako T, Kimura N.The activities of the enzymes involved in the malate-aspartate shuttle and lactate dehydrogenase (LDH) and the pattern of the isoenzymes of LDH were determined in plasma and peripheral leukocytes of lactating Holstein cows and thoroughbred riding horses as representative herbivorous animals. In the horse plasma, LDH activities were significantly lower and AST activities were significantly higher than those in the cow plasma. The specific activities of cytosolic malate dehydrogenase (MDH), LDH and AST in the horse leukocytes were higher than those in the cows. The cytosolic ratio of MDH/LDH act...
Lead poisoning combined with cadmium in sheep and horses in the vicinity of non-ferrous metal smelters.
The Science of the total environment    June 12, 2003   Volume 309, Issue 1-3 117-126 doi: 10.1016/S0048-9697(03)00011-1
Liu ZP.The diagnosis of lead poisoning combined with cadmium in sheep and horses living on farmland in the vicinity of non-ferrous metal smelters in Baiyin of Gansu province in China was based on laboratory findings as well as clinical signs. The concentrations of lead, cadmium, copper and zinc in soils, water, forages, feed and blood, hair and tissues of affected sheep and horses were determined in the surroundings of the smelters in Baiyin and controls. Haematological values were also measured. The concentrations of these elements in soils, forages, water and feed were significantly higher than tho...
An improved Pythium insidiosum-vaccine formulation with enhanced immunotherapeutic properties in horses and dogs with pythiosis.
Vaccine    June 12, 2003   Volume 21, Issue 21-22 2797-2804 doi: 10.1016/s0264-410x(03)00225-1
Mendoza L, Mandy W, Glass R.The immunotherapeutic properties of a new Pythium insidiosum-vaccine formulation (PIV), was evaluated in 18 horses and 6 dogs with proven pythiosis from different enzootic areas in the United States. All injected horses but one responded with a weak (=29 mm, n=3), a mild (30-90 mm, n=7) or a strong (=100 mm, n=7) inflammatory reactions at the site of injection. Three equines with weak or negative reactions at the injection site were not cured. Seven equines with strong reactions at their injection sites, however, were cured. Six of the eight horses with mild reactions were also cured. The rema...
Optimising vaccination strategies in equine influenza.
Vaccine    June 12, 2003   Volume 21, Issue 21-22 2862-2870 doi: 10.1016/s0264-410x(03)00156-7
Park AW, Wood JL, Newton JR, Daly J, Mumford JA, Grenfell BT.A stochastic model of equine influenza (EI) is constructed to assess the risk of an outbreak in a Thoroughbred population at a typical flat race training yard. The model is parameterised using data from equine challenge experiments conducted by the Animal Health Trust (relating to the latent and infectious period of animals) and also published data on previous epidemics (to estimate the transmission rate for equine influenza). Using 89 ponies, an empirical relationship between pre-challenge antibody and the probability of becoming infectious is established using logistic regression. Changes in...
Acceleration of cartilage repair by genetically modified chondrocytes over expressing bone morphogenetic protein-7.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society    June 12, 2003   Volume 21, Issue 4 573-583 doi: 10.1016/S0736-0266(02)00264-4
Hidaka C, Goodrich LR, Chen CT, Warren RF, Crystal RG, Nixon AJ.Cartilage has a limited capacity to heal. Although chondrocyte transplantation is a useful therapeutic strategy, the repair process can be lengthy. Previously we have shown that over expression of bone morphogenetic protein-7 (BMP-7) in chondrocytes by adenovirus-mediated gene transfer leads to increased matrix synthesis and cartilage-like tissue formation in vitro. In this context we hypothesized that implantation of genetically modified chondrocytes expressing BMP-7 would accelerate the formation of hyaline-like repair tissue in an equine model of cartilage defect repair. Methods: Chondrocyt...
Are uniform regional safety factors an objective of adaptive modeling/remodeling in cortical bone?
The Journal of experimental biology    June 11, 2003   Volume 206, Issue Pt 14 2431-2439 doi: 10.1242/jeb.00466
Skedros JG, Dayton MR, Sybrowsky CL, Bloebaum RD, Bachus KN.It has been hypothesized that a major objective of morphological adaptation in limb-bone diaphyses is the achievement of uniform regional safety factors between discrete cortical locations (e.g. between cranial and caudal cortices at mid-diaphysis). This hypothesis has been tested, and appears to be supported in the diaphyses of ovine and equine radii. The present study more rigorously examined this question using the equine third metacarpal (MC3), which has had functionally generated intracortical strains estimated by a sophisticated finite element model. Mechanical properties of multiple mid...
Non-fatal aflatoxicosis in Arabian horses in Iraq.
The Veterinary record    June 7, 2003   Volume 152, Issue 21 657-658 doi: 10.1136/vr.152.21.657
Hasso SA.No abstract available
Aid to the antemortem diagnosis of Fell pony foal syndrome by the analysis of B lymphocytes.
The Veterinary record    June 7, 2003   Volume 152, Issue 20 618-621 doi: 10.1136/vr.152.20.618
Thomas GW, Bell SC, Phythian C, Taylor P, Knottenbelt DC, Carter SD.Fell pony foals are affected by a congenital fatal immunodeficiency that commonly leads to anaemia and lymphopenia. Previous work has shown that the foals' circulating subpopulations of CD4 and CD8 T lymphocytes are unaffected. In this study it was shown that the mean population of B lymphocytes in 10 affected foals was less than 10 per cent of that in normal foals.
The prevalence and transmission to exotic equids (Equus quagga antiquorum, Equus przewalskii, Equus africanus) of intestinal nematodes in contaminated pasture in two wild animal parks.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians    June 7, 2003   Volume 32, Issue 2 209-216 doi: 10.1638/1042-7260(2001)032[0209:TPATTE]2.0.CO;2
Epe C, Kings M, Stoye M, Böer M.Wild equids maintained in large enclosures may suffer from helminth diseases because common hygiene practices have only limited effects on parasite populations. Weekly monitoring of helminth prevalences and pasture infestation was performed for 1 yr in several extensive maintenance systems of two wildlife parks with similar climates to determine when veterinary intervention to control parasites would be useful. We also sought evidence of natural immunogenic reactions among herds of Chapman zebras (Equus quagga antiquorum), Przewalski's horses (Equus przewalskii) and dwarf donkeys (Equus asinus...
Chondrocyte apoptosis, inflammatory mediators and equine osteoarthritis.
Veterinary journal (London, England : 1997)    June 6, 2003   Volume 166, Issue 1 3-4 doi: 10.1016/s1090-0233(02)00270-8
Clegg PD, Mobasheri A.No abstract available
Articular chondrocyte apoptosis in equine osteoarthritis.
Veterinary journal (London, England : 1997)    June 6, 2003   Volume 166, Issue 1 52-57 doi: 10.1016/s1090-0233(02)00305-2
Kim DY, Taylor HW, Moore RM, Paulsen DB, Cho DY.Osteoarthritis (OA) is the most common joint disease in horses. Chondrocyte apoptosis has been implicated as a major pathological OA change in humans and experimental animals but no studies have been performed on equine OA. Articular cartilage was collected from three normal and five OA horses. Histopathological changes were scored by a modified Mankin grading system. A terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) assay was performed to identify chondrocyte apoptosis. Nitric oxide (NO) production from chondrocytes was indirectly evaluated by immunohistochemistr...
Heightened security precautions may cause problems for horse transportation.
Journal of the American Veterinary Medical Association    June 6, 2003   Volume 222, Issue 11 1495-1496 
No abstract available
Results of the 2002 AVMA survey of US pet-owning households regarding use of veterinary services and expenditures.
Journal of the American Veterinary Medical Association    June 6, 2003   Volume 222, Issue 11 1524-1525 doi: 10.2460/javma.2003.222.1524
Wise JK, Heathcott BL, Shepherd AJ.No abstract available
Effects of novelty stress on neuroendocrine activities and running performance in thoroughbred horses.
Journal of neuroendocrinology    June 6, 2003   Volume 15, Issue 7 638-648 doi: 10.1046/j.1365-2826.2003.01042.x
Hada T, Onaka T, Takahashi T, Hiraga A, Yagi K.This study investigated the effects of novelty stress on neuroendocrine activities and running performance in Thoroughbred horses. First, to examine the neuroendocrine responses to novelty stress, we exposed horses to two types of novel environmental stimuli (audiovisual or novel field stimuli). After the stimuli, plasma concentrations of vasopressin, catecholamines and adrenocorticotropin (ACTH), as well as heart rates, were significantly increased in each experiment. Second, we investigated neuroendocrine activities during incremental exercise. Plasma concentrations of vasopressin, catechola...
Advanced technology brings equine dentistry into light of day.
Dentistry today    June 5, 2003   Volume 22, Issue 5 38-40 
No abstract available
Platelet-rich plasma gel promotes differentiation and regeneration during equine wound healing.
Experimental and molecular pathology    June 5, 2003   Volume 74, Issue 3 244-255 doi: 10.1016/s0014-4800(03)00017-0
Carter CA, Jolly DG, Worden CE, Hendren DG, Kane CJ.Nonhealing wounds of the lower equine limb represent a challenging model. The platelet is a natural source of a myriad of growth factors and cytokines that promote wound healing. This study evaluates the potential of platelet derived factors to enhance wound healing in the lower equine limb. Platelets were isolated from horse blood and activated with thrombin, a process known to induce growth factor release. This produced a platelet gel composed of platelet-rich plasma (PRP). To test this all-natural wound healant, 2.5-cm(2) full thickness cutaneous wounds were created below the knee and hock ...
Intravascular hemolysis associated with liver disease in a horse with marked neutrophil hypersegmentation.
Journal of veterinary internal medicine    May 31, 2003   Volume 17, Issue 3 360-363 
Ramaiah SK, Harvey JW, Giguère S, Franklin RP, Crawford PC.No abstract available
Genetics. First cloned mule races to finish line.
Science (New York, N.Y.)    May 31, 2003   Volume 300, Issue 5624 1354 doi: 10.1126/science.300.5624.1354a
Holden C.No abstract available
Effect of growth hormone (GH) on in vitro nuclear and cytoplasmic oocyte maturation, cumulus expansion, hyaluronan synthases, and connexins 32 and 43 expression, and GH receptor messenger RNA expression in equine and porcine species.
Biology of reproduction    May 28, 2003   Volume 69, Issue 3 1013-1022 doi: 10.1095/biolreprod.103.015602
Marchal R, Caillaud M, Martoriati A, Gérard N, Mermillod P, Goudet G.The aim of this study was to investigate the role of growth hormone (GH) on in vitro cumulus expansion and oocyte maturation in equine and porcine cumulus-oocyte complexes (COCs), and to approach its way of action. Equine COCs were cultured in a control medium (TCM199, 5 mg/ml BSA, 1 microg/ml estradiol, and antibiotics) supplemented with either 0.5 microg/ml equine GH or 5 microg/ml equine LH. Porcine COCs were cultured in a basal medium (TCM199 with 570 microM cysteamine) supplemented with 0, 0.1, 0.5, or 1 microg/ml porcine GH or in a control medium (basal medium with 10 ng/ml epidermal gro...
Equine passports.
The Veterinary record    May 24, 2003   Volume 152, Issue 19 604 
Ellis RN.No abstract available
Case-control study to investigate risk factors for horse falls in hurdle racing in England and Wales.
The Veterinary record    May 24, 2003   Volume 152, Issue 19 583-587 doi: 10.1136/vr.152.19.583
Pinchbeck GL, Clegg PD, Proudman CJ, Morgan KL, French NP.Between March 1, 2000 and August 31, 2001, a case-control study was conducted on 12 racecourses in England and Wales to identify and quantify the risk factors associated with horse falls in hurdle races. The cases and controls were defined so that variables relating to the horse, the jockey, the race and racecourse, and the jump could be considered. The cases were defined as a jumping effort at a hurdle flight that resulted in a fall, and the controls were defined as a successful jump over a hurdle at any of the 12 racecourses within 14 days before or after the case fall. Conditional logistic ...
Prevalence of strongyle nematodes in naturally infected ponies of different ages and during different seasons of the year in Louisiana.
The Journal of parasitology    May 23, 2003   Volume 89, Issue 2 309-314 doi: 10.1645/0022-3395(2003)089[0309:POSNIN]2.0.CO;2
Chapman MR, French DD, Klei TR.One hundred and seventeen ponies were surveyed for the seasonal prevalence of strongyloid parasites, particularly cyathostomes, and for host- and age-related differences in these infections. For 56 ponies, all stages of the cyathostome life cycle, both mucosal and luminal, were enumerated. Total numbers of cyathostomes and percentage of developing larvae (DL) encysted in the mucosa remained constant in all 4 seasons of the year, whereas a significant increase in the percentage of adults in the cyathostome population occurred in fall. In yearling ponies, encysted early third-stage larvae consti...
Prevalence of Sarcocystis infection in horses in Mongolia.
The Southeast Asian journal of tropical medicine and public health    May 22, 2003   Volume 33, Issue 4 718-719 
Fukuyo M, Battsetseg G, Byambaa B.Sarcocystis infection was detected in 93% of horses in Mongolia. Using the compress method, sarcocysts were found in the muscles of the diaphragm, heart and tongue in 40 of the 43 horses that were slaughtered at the Makh Impex Meat Company in Ulaan Baatar in July 1998. The muscle of the tongue showed the highest rate (97.5%) of infection. The distribution of sarcocysts in the muscles was positively correlated with horse age; the rate of detection was significantly lower (p=0.01) in the under 10 year old group than the older group. All horses were apparently healthy and were slaughtered for hum...
[Effects of excess caloric fat feeding on the lipid metabolism in Shetland ponies].
DTW. Deutsche tierarztliche Wochenschrift    May 22, 2003   Volume 110, Issue 4 170-174 
Dühlmeier R, Gück T, Deegen E, Busche R, Sallmann HP.To investigate the influence of overweight and dietary fat supplementation on lipid and insulin glucose metabolism of Shetland ponies, eight Shetland pony geldings were fed a hypercaloric (30 MJ DE/150 kg bwt. and day) fat diet (10% fat as soybean oil) or a carbohydrate control diet for nine months until ponies gained an overweight of 15%. Afterwards oral glucose tolerance tests (oGTT; 5, 6 mmol/kg bwt.) were performed after a 12 hour fast and after a fast which led to an increase of plasma triglyceride concentrations to a threshold of 3 mmol/l (36-65 hrs.). Plasma concentrations of glucose, i...
Excessive airway mucus in horses with pulmonary disease: is it caused by mucus overproduction, decreased clearance or both?
Equine veterinary journal    May 21, 2003   Volume 35, Issue 3 222-223 doi: 10.2746/042516403776148192
Dixon PM, Pirie RS.No abstract available
A practical approach to anthelmintic resistance.
Equine veterinary journal    May 21, 2003   Volume 35, Issue 3 218-219 doi: 10.2746/042516403776148174
Sangster N.No abstract available
Are the material properties and matrix composition of equine flexor and extensor tendons determined by their functions?
Equine veterinary journal    May 21, 2003   Volume 35, Issue 3 314-318 doi: 10.2746/042516403776148327
Batson EL, Paramour RJ, Smith TJ, Birch HL, Patterson-Kane JC, Goodship AE.Injury to the superficial digital flexor tendon (SDFT) is common in competition horses. The SDFT contributes to locomotory efficiency by storing energy; such tendons have low safety margins. Tendons which merely position the limb, including the opposing common digital extensor tendon (CDET), are rarely injured. The current failure of strategies to prevent or effectively treat injury to the SDFT indicates the importance of understanding how it differs from tendons which are not injury-prone. Objective: That the structural and material properties and matrix composition of the SDFT and CDET diffe...
Practice is alive with the sounds of horses.
Equine veterinary journal    May 21, 2003   Volume 35, Issue 3 224-225 doi: 10.2746/042516403776148345
Derksen FJ.No abstract available