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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Outcome of epidural catheterization for delivery of analgesics in horses: 43 cases (1998-2001).
Journal of the American Veterinary Medical Association    May 24, 2003   Volume 222, Issue 10 1394-1398 doi: 10.2460/javma.2003.222.1394
Martin CA, Kerr CL, Pearce SG, Lansdowne JL, Bouré LP.To determine reasons for epidural catheter placement among horses examined at a veterinary teaching hospital, efficacy of epidural administration of analgesics, duration of catheter placement, reasons for catheter removal, and complications encountered. Methods: Retrospective study. Methods: 43 horses. Methods: Medical records were reviewed. Results: A total of 50 epidural catheters were placed in the 43 horses. Underlying conditions included fractures, lacerations, septic arthritis, myositis, perineal injuries, and cellulitis. Horses ranged from 2 to 21 years old and weighed between 365 and 7...
Bilateral optic disc colobomas in a Quarter Horse filly.
Equine veterinary journal    May 21, 2003   Volume 35, Issue 3 325-327 doi: 10.2746/042516403776148237
Bildfell R, Watrous B, Maxwell S, Schlipf J, Reynolds M.No abstract available
Spectral analysis of respiratory noise in horses with upper airway disorders.
Equine veterinary journal    May 21, 2003   Volume 35, Issue 3 264-268 doi: 10.2746/042516403776148228
Franklin SH, Usmar SG, Lane JG, Shuttleworth J, Burn JF.It has long been recognised that the production of abnormal respiratory sounds by horses during exercise is frequently associated with upper airway obstructions. Respiratory acoustic measurements have shown promise in investigation of upper airway disorders in man and, more recently, in horses with experimentally-induced obstructions. Objective: To evaluate sounds from exercising horses with naturally occurring dynamic obstructions of the upper respiratory tract and to compare these with those from normal horses in order to determine whether different obstructions produce characteristic spectr...
Pain associated with the sacroiliac joint region: a clinical study of 74 horses.
Equine veterinary journal    May 21, 2003   Volume 35, Issue 3 240-245 doi: 10.2746/042516403776148255
Dyson S, Murray R.There has been no large study of horses with suspected sacroiliac (SI) joint region pain in which the clinical diagnosis has been supported by either abnormal radiopharmaceutical activity in the SI joint region or by periarticular infiltration of local anaesthetic solution. Objective: To describe the clinical features of horses with SI joint region pain, to document the age, breed, sex, discipline, size and conformation of affected horses and to compare these with the author's (SD) normal case population and to document the results of infiltration of local anaesthetic solution around the SI jo...
Idiopathic mucosal lesions of the arytenoid cartilages of 21 Thoroughbred yearlings: 1997-2001.
Equine veterinary journal    May 21, 2003   Volume 35, Issue 3 276-281 doi: 10.2746/042516403776148318
Kelly G, Lumsden JM, Dunkerly G, Williams T, Hutchins DR.Mucosal ulcers and, occasionally, small granulomas on the axial surface of one or both arytenoid cartilages have been found in TB yearlings presented for post sale endoscopic examination. Objective: To determine the incidence, endoscopic characteristics and outcome of a group of Thoroughbred yearlings affected with mucosal ulcers and granulomas of the arytenoid cartilage. Objective: The incidence of mucosal ulceration of the arytenoid cartilages of yearling Thoroughbreds is relatively high compared to other upper airway abnormalities; and that the majority of mucosal ulcers heal uneventfully, ...
Corneal esthesiometry in the healthy horse.
Veterinary ophthalmology    May 20, 2003   Volume 6, Issue 2 151-155 doi: 10.1046/j.1463-5224.2003.00283.x
Kaps S, Richter M, Spiess BM.To determine corneal sensitivity in healthy adult horses in order to establish reference values. Methods: One hundred eyes of 50 healthy adult horses. Methods: Corneal sensitivity was determined by evaluating the corneal touch threshold (CTT) in five different corneal regions using a Cochet-Bonnet esthesiometer. Results: Comparing CTT values (in mm filament length) of the five prescribed corneal regions revealed regional variations in corneal sensitivity, with the central region (21.15 +/- 6.23 mm) being the most sensitive, followed by the nasal (20.75 +/- 5.14 mm), temporal (20.70 +/- 5.37 mm...
Laryngeal reinnervation in the horse.
The Veterinary clinics of North America. Equine practice    May 16, 2003   Volume 19, Issue 1 189-viii doi: 10.1016/s0749-0739(02)00073-1
Fulton IC, Stick JA, Derksen FJ.Left laryngeal hemiplegia is a frustrating condition for the equine athlete and equine veterinarian. Treatment for the past 30 years has centered on the prosthetic laryngoplasty ("tie-back") with or without ventriculectomy. Laryngeal reinnervation has been used successfully in people and has been shown experimentally to benefit affected horses. This article reviews equine laryngeal reinnervation using the nerve muscle pedicle graft and describes the surgical technique, its complications, and the follow-up in 146 cases treated over the past 10 years. Also discussed is ongoing research into stim...
Descriptive epidemiology of late-term abortions associated with the mare reproductive loss syndrome in central Kentucky. Cohen ND, Carey VJ, Donahue JG, Seahorn JL, Harrison LR.Epidemiological and pathological findings of 433 late-term abortions associated with the mare reproductive loss syndrome (MRLS) in central Kentucky were identified by reviewing the records of the University of Kentucky Livestock Diseases Diagnostic Center. The distribution of dates of abortion was clustered during a brief period of time, presumably from a simultaneous environmental exposure. The most common pathological findings were microscopic pulmonary lesions consisting of squamous epithelial cells present in alveoli with or without concurrent infiltration of inflammatory cells (neutrophil...
West Nile virus encephalomyelitis in horses: 46 cases (2001).
Journal of the American Veterinary Medical Association    May 3, 2003   Volume 222, Issue 9 1241-1247 doi: 10.2460/javma.2003.222.1241
Porter MB, Long MT, Getman LM, Giguère S, MacKay RJ, Lester GD, Alleman AR, Wamsley HL, Franklin RP, Jacks S, Buergelt CD, Detrisac CJ.To determine signalment, clinical findings, results of diagnostic testing, outcome, and postmortem findings in horses with West Nile virus (WNV) encephalomyelitis. Methods: Retrospective study. Methods: 46 horses with WNV encephalomyelitis. Methods: Clinical data were extracted from medical records of affected horses. Results: On the basis of clinical signs and results of serologic testing, WNV encephalomyelitis was diagnosed in 46 of 56 horses with CNS signs. Significantly more males than females were affected. Increased rectal temperature, weakness or ataxia, and muscle fasciculations were t...
Ultrasonographic findings in horses with right dorsal colitis: five cases (2000-2001).
Journal of the American Veterinary Medical Association    May 3, 2003   Volume 222, Issue 9 1248-1251 doi: 10.2460/javma.2003.222.1248
Jones SL, Davis J, Rowlingson K.To determine whether ultrasonography would be useful in the diagnosis of right dorsal colitis in horses. Methods: Retrospective study. Methods: 5 horses with right dorsal colitis and 15 healthy adult horses. Methods: Mural thickness and appearance of the right dorsal colon were determined from ultrasonographic images obtained at right intercostal spaces 10, 11, 12, 13, and 14. Results: The right dorsal colon could be imaged most consistently at the right 11th, 12th, and 13th intercostal spaces, below the margin of the lung and axial to the liver. Mural thickness measured from ultrasonographic ...
Diagnostic methods applied to analysis of an outbreak of equine influenza in a riding school in which vaccine failure occurred.
Veterinary microbiology    April 26, 2003   Volume 93, Issue 4 291-306 doi: 10.1016/s0378-1135(03)00029-4
van Maanen C, van Essen GJ, Minke J, Daly JM, Yates PJ.An outbreak of equine influenza H3N8 in a riding school is described retrospectively with emphasis on diagnosis and putative vaccine failure. In March 1995 an outbreak of equine influenza occurred among 11 horses in a riding school, where most horses had received basic primary immunizations and several booster vaccinations against influenza. Six of the 11 diseased horses had received their last booster vaccination within 5 months of the outbreak. Nevertheless, the influenza infection spread rapidly and clinical manifestations were prominent with frequent, harsh, dry coughing often accompanied ...
Characterization of Clostridium difficile isolates from foals with diarrhea: 28 cases (1993-1997).
Journal of the American Veterinary Medical Association    April 12, 2003   Volume 220, Issue 1 67-73 doi: 10.2460/javma.2002.220.67
Magdesian KG, Hirsh DC, Jang SS, Hansen LM, Madigan JE.To determine molecular characteristics of Clostridium difficile isolates from foals with diarrhea and identify clinical abnormalities in affected foals. Methods: Retrospective study. Methods: 28 foals with C difficile-associated diarrhea. Methods: Toxigenicity, molecular fingerprinting, and antibiotic susceptibility patterns were determined. Information on signalment, clinical findings, results of clinicopathologic testing, whether antimicrobials had been administered prior to development of diarrhea, and outcome was obtained from the medical records. Results: Twenty-three (82%) foals survived...
Evaluation of a commercially available hyperimmune plasma product for prevention of naturally acquired pneumonia caused by Rhodococcus equi in foals.
Journal of the American Veterinary Medical Association    April 12, 2003   Volume 220, Issue 1 59-63 doi: 10.2460/javma.2002.220.59
Giguère S, Gaskin JM, Miller C, Bowman JL.To determine efficacy of a commercially available hyperimmune plasma product for prevention of naturally acquired pneumonia caused by Rhodococcus equi in foals. Methods: Randomized clinical trial. Methods: 165 foals. Methods: Foals were randomly assigned to 1 of 2 groups (hyperimmune plasma or nontreated controls). Foals with failure of passive transfer (FPT) of immunity were treated with hyperimmune plasma and evaluated as a third group. Foals that received plasma were given 950 ml between 1 and 10 days of age and between 30 and 50 days of age. A tracheobronchial aspirate was obtained from fo...
Desmitis of the straight sesamoidean ligament in horses: 9 cases (1995-1997).
Journal of the American Veterinary Medical Association    April 11, 2003   Volume 222, Issue 7 973-977 doi: 10.2460/javma.2003.222.973
Schneider RK, Tucker RL, Habegger SR, Brown J, Leathers CW.To determine clinical signs, diagnostic findings, and outcome for horses with desmitis of the straight sesamoidean ligament (SSL) near its insertion on the middle phalanx. Methods: Retrospective study. Methods: 9 horses. Methods: Medical records were reviewed, and information on signalment, history, clinical signs, diagnostic findings, and treatment was obtained. Follow-up information was obtained through telephone conversations with owners. Results: In all horses, the diagnosis was made by use of high-resolution ultrasonography. Seven horses had moderate lameness on initial examination; lamen...
Pharmacokinetics and clinical utility of sodium bromide (NaBr) as an estimator of extracellular fluid volume in horses.
Journal of veterinary internal medicine    April 10, 2003   Volume 17, Issue 2 213-217 doi: 10.1111/j.1939-1676.2003.tb02436.x
Fielding CL, Magdesian KG, Elliott DA, Craigmill AL, Wilson WD, Carlson GP.The purpose of this study was to describe the pharmacokinetics of bromide in horses and to evaluate the corrected bromide space as an indicator of extracellular fluid volume (ECFV) in horses after the administration of a single dose of bromide by intravenous infusion. Sodium bromide (30 mg/kg of body weight, IV) was administered to 6 clinically healthy mares over a period of 3 minutes. Blood samples were collected before infusion and at intervals between 0.5 hours and 53 days after infusion. Mean elimination half-life (harmonic mean) was 126 hours (5.2 days), clearance was 1.4 +/- 0.09 mL/(kg ...
Quantitative electromyographic examination in myogenic disorders of 6 horses.
Journal of veterinary internal medicine    April 10, 2003   Volume 17, Issue 2 185-193 doi: 10.1111/j.1939-1676.2003.tb02432.x
Wijnberg ID, Franssen H, Jansen GH, Back W, van der Kolk JH.Electromyographic needle examination (EMG), including the semiautomatic quantitative analysis of motor unit action potential (MUAP), is an important diagnostic tool for myopathy in humans. The diagnostic possibilities of this technique have not been fully explored in horses; however, recent studies have shown that MUAP analysis can be performed in conscious horses. To determine the diagnostic possibilities of EMG in horses, we compared the EMG results of the subclavian muscle, the triceps, and the lateral vastus muscle in 6 equine patients thought to have myogenic disorders with those in 7 nor...
Idiopathic systemic granulomatous disease with encephalitis in a horse.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine    April 2, 2003   Volume 50, Issue 2 108-112 doi: 10.1046/j.1439-0442.2003.00492.x
Peters M, Graf G, Pohlenz J.A 14-year-old standardbred mare with clinically suspected acute bronchitis was killed because of rapidly progressing central nervous disturbances. Necropsy revealed systemic granulomatous inflammation and vasculitis involving the lungs, thoracic lymph nodes, ribs, and liver. In the cerebrum there was a severe subacute bilateral encephalitis and malacia predominately affecting the white matter, and vasculitis with perivascular infiltration of lymphocytes, macrophages, and giant cells. A causative infectious agent could not be detected by Ziehl-Neelsen, Grocott, or Giemsa stains, by periodic aci...
Overview of suspected adverse reactions to veterinary medicinal products reported in South Africa (March 2001 – February 2002).
Journal of the South African Veterinary Association    April 1, 2003   Volume 73, Issue 4 227-229 doi: 10.4102/jsava.v73i4.594
Naidoo V, Gehring R.An overview of reports of suspected adverse drug reactions received by the Veterinary Pharmacovigilance and Medicines Information Centre during the period March 2001 to February 2002 is given. A total of 77 reports were received. The majority of reports involved suspected adverse reactions that occurred in dogs and cats. Most products implicated in the reports were Stock Remedies. The products were predominantly administered either by veterinarians or trained paraveterinary professionals. Although the majority of reports were received from veterinary pharmaceutical companies, the proportion of...
Equine immune-mediated hemolytic anemia associated with Clostridium perfringens infection.
Veterinary clinical pathology    March 26, 2003   Volume 32, Issue 1 22-26 doi: 10.1111/j.1939-165x.2003.tb00308.x
Weiss DJ, Moritz A.Previous studies have suggested an association between equine immune-mediated hemolytic anemia and clostridial infections or neck abscesses. Objective: The purpose of this report was to describe and characterize the hematologic abnormalities in a horse with Clostridium-associated immune-mediated hemolytic anemia. We also retrospectively evaluated hematologic abnormalities in 8 horses with clostridial myositis or subcutaneous emphysema. Methods: A 7-year-old Foreign Warm-Blood gelding was evaluated for anemia and a cervical abscess. CBCs and reticulocyte counts were obtained using an Advia 120 ...
[Clinical treatment of equestrian injuries in Groningen, 1990-1998: serious long-term effects].
Nederlands tijdschrift voor geneeskunde    March 21, 2003   Volume 147, Issue 5 204-208 
Dekker R, Groothoff JW, Eisma WH, ten Duis HJ.To determine whether equestrian injuries result in long-term residual symptoms and to establish the risk factors for these outcomes. Methods: Retrospective, descriptive. Methods: A total of 88 patients older than 17 years of age who had been admitted to the Department of Surgery, University Hospital Groningen during the period 1990-1998 because of an equestrian injury were included in the study. After an average period of five years an inventory was made using the Sickness Impact Profile 68 (SIP68), if absenteeism from work or sport and disabilities or handicaps were experienced. Following thi...
Nonmosaic X trisomy, detected by chromosome painting, in an infertile mare.
Equine veterinary journal    March 18, 2003   Volume 35, Issue 2 209-210 doi: 10.2746/042516403776114207
Bugno M, Slota E, Wieczorek M, Yang F, Buczynski J, Switonski M.No abstract available
Invasive ductal carcinoma of the mammary gland in a mare.
Veterinary pathology    March 12, 2003   Volume 40, Issue 1 86-91 doi: 10.1354/vp.40-1-86
Hirayama K, Honda Y, Sako T, Okamoto M, Tsunoda N, Tagami M, Taniyama H.A 21-year-old thoroughbred mare had a 35 x 14 x 10 cm mass involving the mammary gland. Metastases were found in the kidneys, lungs, skeletal muscles, and regional lymph nodes. Histopathologic examination of the tumor revealed a ductal solid carcinoma with extensive intraductal and intralobular involvement and focal infiltration of the adjacent stroma. The intralobular neoplasms were divided into irregularly shaped islands and sheets of polygonal and spindle-shaped epithelial cells by thick or thin fibrous connective tissue bundles. The neoplastic cells had a small or moderate amount of cytopl...
Camelid mucoutaneous fibropapillomas: clinicopathologic findings and association with papillomavirus.
Veterinary pathology    March 12, 2003   Volume 40, Issue 1 103-107 doi: 10.1354/vp.40-1-103
Schulman FY, Krafft AE, Janczewski T, Reupert R, Jackson K, Garner MM.Five camelid mucocutaneous fibropapillomas with histologic features similar to equine sarcoids were diagnosed. They were characterized by a dermal fibroblastic proliferation and overlying, often ulcerated hyperplastic epidermis with thin rete pegs extending down into the dermis. Two of the tumors came from llamas and three from alpacas. Four of the animals were 6-year-old females. The fifth was a 6-year-old castrated male. The fibropapillomas were located on the nose, lip, and cheeks. One of the llama tumors waxed and waned before surgery and recurred and spread after surgery. None of the othe...
Equine referrals for two ongoing studies.
The Veterinary record    March 7, 2003   Volume 152, Issue 7 216 
Jeffcott LB, Dobson J, Roberts C, Slater J, Henson F.No abstract available
Alkaline phosphatase in stallion semen: characterization and clinical applications.
Theriogenology    March 7, 2003   Volume 60, Issue 1 1-10 doi: 10.1016/s0093-691x(02)00956-1
Turner RM, McDonnell SM.Significant amounts of alkaline phosphatase (AP) activity have been found in semen plasma from numerous species. In species in which the majority of semen plasma AP (SPAP) activity originates from the epididymis and testicle, SPAP activity can be used clinically as a marker to differentiate testicular origin azoospermia or oligospermia from ejaculatory failure. Information on SPAP activity in stallions to date has been limited. In this study, a standard clinical chemistry analyzer was used to determine AP activity in pre-ejaculatory fluid and ejaculates from groups of normal stallions. Additio...
Stress fractures of the tibia and humerus in Thoroughbred racehorses: 99 cases (1992-2000).
Journal of the American Veterinary Medical Association    February 25, 2003   Volume 222, Issue 4 491-498 doi: 10.2460/javma.2003.222.491
O'Sullivan CB, Lumsden JM.To determine clinical characteristics of and outcome in Thoroughbred racehorses with tibial or humeral stress fractures. Methods: Retrospective study. Methods: 99 Thoroughbreds with tibial or humeral stress fractures. Methods: Information obtained from the medical records included history, signalment, and clinical, radiographic, and scintigraphic findings. Outcome was determined by interviewing trainers, performing follow-up examinations, and analyzing race records. Results: Seventy-four tibial stress fractures were identified in 61 Thoroughbreds, and 48 humeral stress fractures were identifie...
Bacteriological and mycological findings, and in vitro antibiotic sensitivity of pathogenic staphylococci in equine skin infections.
The Veterinary record    February 15, 2003   Volume 152, Issue 5 138-141 doi: 10.1136/vr.152.5.138
Chiers K, Decostere A, Devriese LA, Haesebrouck F.No abstract available
Malignant granulosa-theca cell tumor in a two-year-old Miniature Horse. Patrick DJ, Kiupel M, Gerber V, Carr EA.A 2-year-old female Miniature Horse that presented with a history of progressive weight loss, depression, and diarrhea was diagnosed at necropsy with a highly malignant abdominal neoplasm involving the left ovary, kidneys, adrenal glands, intestines, and various abdominal and thoracic lymph nodes. Microscopic examination of these masses revealed large pleomorphic cells that stained positive for vimentin and inhibin and negative for epithelial membrane antigen and placental alkaline phosphatase. Ultrastructural examination of the cells revealed a high nucleocytoplasmic ratio and indented euchro...
What is your diagnosis? Cholestasis, hepatic cholelithiasis.
Journal of the American Veterinary Medical Association    February 5, 2003   Volume 222, Issue 3 289-290 doi: 10.2460/javma.2003.222.289
Brandon B, Stanley C.No abstract available
Influence of liver copper status of mare and newborn foal on the development of osteochondrotic lesions.
Equine veterinary journal    January 30, 2003   Volume 35, Issue 1 67-71 doi: 10.2746/042516403775467469
van Weeren PR, Knaap J, Firth EC.To elucidate the highly contentious role of copper in the pathogenesis of osteochondrosis. Objective: There would be no relationship between liver copper concentration of mares and foals and incidence of radiographically detectable osteochondrotic lesions in foals and yearlings was tested. Methods: Liver copper concentration was assessed in biopsies taken within 4 days after birth from both mares and foals and from the same foals at age 5 months. Biopsies were taken in the standing, sedated animal under ultrasonographic guidance. Radiographs were taken of both hocks (lateromedial, dorsoplantar...